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Young
Kinds of Young Terms modified by Young Selected AbstractsTHE YOUNG HELD TO RANSOM , A PUBLIC CHOICE ANALYSIS OF THE UK STATE PENSION SYSTEMECONOMIC AFFAIRS, Issue 1 2008Philip Booth As populations age, it will become increasingly difficult to reform state pension systems. Reform will not be impossible, but the process of ,buying off' interest groups will be expensive. State pension provision must use the contributory principle combined with an accruals system , though private pension provision would be better still. There are serious flaws in the so-called ,citizens pension' much promoted by interest groups in the UK. [source] Osteointegration of titanium and hydroxyapatite rough surfaces in healthy and compromised cortical and trabecular bone: in vivo comparative study on young, aged, and estrogen-deficient sheepJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 9 2007Veronica Borsari Abstract The osteointegration rate of titanium (Ti; TI01) and duplex Ti plus HA (HT01) coating systems with high surface roughness was investigated in healthy, aged, and oestrogen-deficient sheep. After having evaluated the bone quality, TI01 and HT01 rods were implanted in the tibial diaphyses (two implants for each tibia) and epiphyses (1 implant for each tibia) of five young (YOUNG), five aged (AGED), and five aged and ovariectomized (OVX) sheep. The iliac crest trabecular bone volume (BV/TV) and number (Tb.N) in OVX sheep were respectively 33.5% and 28.5% lower than in YOUNG sheep (p,<,0.005) and lower than in the AGED group (BV/TV, ,17%; Tb.N, ,13.5%; not significant); in the OVX group the trabecular separation was 77.9% higher than in YOUNG (p,<,0.05) and 30.9% higher than in AGED animals. Lumbar vertebrae L5 bone mineral density was significantly lower in AGED (8.9%, p,<,0.05) and OVX sheep (19.3%, p,<,0.0005) when compared with YOUNG animals. Five samples of five sheep from each group were analyzed for each observation. At 3 months, in cortical bone both affinity index and pushout test results showed no significant differences between the two materials in each group of animals. In trabecular bone, the affinity index of HT01 was significantly higher than that of TI01 in each group of animals (YOUNG, 90.7%; AGED, 76.9%; OVX, 49.9%) with no significant differences between groups. In conclusion, the performance of TI01 and HT01 surfaces was high not only in YOUNG, but also in OVX animals and, therefore, they might be useful for aged and osteoporotic patients. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 25:1250,1260, 2007 [source] CHEWING PATTERNS OF VARIOUS TEXTURE FOODS STUDIED BY ELECTROMYOGRAPHY IN YOUNG AND ELDERLY POPULATIONSJOURNAL OF TEXTURE STUDIES, Issue 4 2002KAORU KOHYAMA ABSTRACT The effects of food texture on the chewing patterns of elderly and young people, masticatory recordings using electromyography (EMG) were carried out. Fourteen French adults (mean 29.4 years) and 23 elderly (mean 67.7 years) participated. Six food products (rice, beef, cheese, crispy bread, apple and peanuts) were tested. The chewing pattern of elderly subjects was characterized by a significant increase of number of chews and chewing duration for all foods except rice. Whatever the food type, muscle activity per chew (mean amplitude × burst duration) was lower for elderly than for young subjects. Single chews appeared less effective for food reduction in elderly than in young subjects. This can be partly compensated for by increasing the chewing duration and number of chews. No significant difference was found between both groups of subject for the total amount of EMG activity required prior to swallow whatever the food chewed. [source] THE DIVISION OF LABOR AND ROUNDABOUT PRODUCTION: ALLYN YOUNG REVISITEDPACIFIC ECONOMIC REVIEW, Issue 3 2003Guang-Zhen Sun First, apart from advancing the state of knowledge, the progressive division of labor that can occur within a given population encourages the adoption of more specialized, differentiated intermediate goods in the production process. Second, the level of division of labor and the extent of the market depend on each other. Using a general equilibrium model with increasing returns to specialization, economies of complementarity between intermediate goods, and transaction costs, we demonstrate that the level of division of labor and the number of intermediate goods increase concurrently as transaction conditions are improved. [source] FARM-RELATED FATAL INJURY OF YOUNG AND OLDER ADULTS IN AUSTRALIA, 1989,1992AUSTRALIAN JOURNAL OF RURAL HEALTH, Issue 4 2002Rebecca J. Mitchell ABSTRACT: This paper describes the types of, and circumstances surrounding, unintentional farm-related fatal injuries involving young and older adults in Australia. Information was obtained from an inspection of coronial files for the period 1989,1992. Around 14% of all farm-related fatalities in Australia during 1989,1992 were of young adults aged 15,24 years and approximately one-quarter were of older adults aged? 55 years. Young adults were commonly fatally injured in motor vehicle incidents and in incidents involving firearms. Tractors were the most common agent involved in fatal incidents involving older adults. Intervention measures to prevent fatalities of older adults in agriculture should focus on the safe use of tractors, while for young adults it appears prevention efforts should centre around safe use of firearms and operation of motor vehicles on the farm. Ways to overcome barriers to the use of injury prevention measures in rural Australia should be further explored. [source] In Memoriam Iris Young 1949-2006CONSTELLATIONS: AN INTERNATIONAL JOURNAL OF CRITICAL AND DEMOCRATIC THEORY, Issue 4 2006Jodi Dean No abstract is available for this article. [source] The Chocolate Tree: A Natural History of Cacao by Allen M. YoungCULTURE, AGRICULTURE, FOOD & ENVIRONMENT, Issue 1-2 2008Nicholas C. Kawa No abstract is available for this article. [source] Packaging design, consumer research, and business strategy: The march toward accountabilityDESIGN MANAGEMENT REVIEW, Issue 4 2002Scott Young It may not be science, but there are research techniques to measure the effectiveness and leverage the results of package designs. Scott Young articulates the possibilities, the limits, and the best uses of this type of design research. Perhaps more valuable, he recommends specific steps managers can take to build collaborative and productive relationships among designers, experts in research, and decision makers in marketing and sales. [source] Respiratory cytology: Differential diagnosis and pitfallsDIAGNOSTIC CYTOPATHOLOGY, Issue 4 2010F.R.C.P.C., Ph.D., Reda S. Saad M.D. Abstract Pulmonary cytology can be challenging and has its share of diagnostic pitfalls. Reactive atypia can occasionally be alarming, leading to diagnostic pitfall for a false-positive diagnosis of malignancy, even for experienced cytopathologists (Naryshkin and Young, Diagn Cytopathol 1993;9:89,97). In addition, cytologic preparations can show an absence of architectural clues, leading to diagnostic difficulties. Some conditions can cytologically as well as clinically and radiographically mimic malignancies, making these pitfalls even more frequent (Bedrossian et al., Lab Med 1983;14:86,95). A recent report stated that "no laboratory that aims to make definitive diagnoses in pulmonary cytology can be spared from false-positive results"(Policarpio-Nicolas and Wick, Diagn Cytopathol 2008;36:13,19). A false-positive finding could produce unnecessary treatment and morbidity, whereas false-negative diagnosis could result in delayed diagnosis and treatment. This review analyzes and illustrates cellular changes and benign entities that can mimic malignancy in respiratory cytology as well as neoplasms that could lead to a false-negative diagnosis. In addition, some specific challenging and difficult aspects in classification of pulmonary malignancies will be discussed. Guidelines and clues are presented to avoid such pitfalls. Diagn. Cytopathol. 2010. © 2009 Wiley-Liss, Inc. [source] Locating Responsibility: The Sphere Humanitarian Charter and Its RationaleDISASTERS, Issue 2 2004James Darcy Criticised by some as a technical initiative that neglects core principles, Sphere was seen by its originators precisely as an articulation of principle. The Humanitarian Charter was the main vehicle through which this was expressed, but its relationship to the Minimum Standards has remained a matter of uncertainty. Specifically, it was unclear in the original (1999) edition of Sphere how the concept of rights informed the Minimum Standards. The revised (2004) edition goes some way to clarifying this in the way the standards are framed, yet the link between the standards and the charter remains unclear. The concern with the quality and accountability of humanitarian assistance, which motivated the attempt to establish system-wide standards through the Sphere Project, was accompanied by a desire to establish such actions in a wider framework of legal and political responsibility. In part, this reflects the conditional nature of the undertaking that agencies make when they adopt Sphere. This aspect of the charter has been neglected, but it is fundamental to an understanding of the standards and their application. This paper considers the rationale of the Sphere Humanitarian Charter and the conceptual model that underpins it. It discusses the relationship between the charter and the Minimum Standards, and the sense in which the latter are properly called ,rights-based' (explored further in a related paper herein by Young and Taylor). The author was closely involved in the conception and drafting of the charter, and this paper attempts to convey some of the thinking that lay behind it. [source] Review article: What's new in early medieval burial archaeology?EARLY MEDIEVAL EUROPE, Issue 1 2002Tania M. Dickinson Books reviewed in this article: John Hines, Karen Høilund Nielsen and Frank Siegmund (eds), The Pace of Change. Studies in Early,Medieval Chronology. Catherine E. Karkov, Kelley M. Wickham,Crowley and Bailey K. Young (eds), Spaces of the Living and the Dead: An Archaeological Dialogue. Sam Lucy, The Early Anglo,Saxon Cemeteries of East Yorkshire. An Analysis and Reinterpretation. Elizabeth O'Brien, Post,Roman Britain to Anglo,Saxon England: Burial Practices Reviewed. Nick Stoodley, The Spindle and the Spear. A Critical Enquiry into the Construction and Meaning of Gender in the Early Anglo,Saxon Burial Rite. [source] Alcohol, suppressed anger and violenceADDICTION, Issue 9 2010Thor Norström ABSTRACT Aims Is alcohol related causally to violence, and if so, is the effect of drinking contingent on suppressed anger such that it is strongest among individuals who are highly inclined to withhold angry feelings? We addressed these questions by analysing panel data using a method that diminishes the effects of confounding factors. Design We analysed data on heavy episodic drinking and violent behaviour from the second (1994) and third (1999) waves of the Young in Norway Longitudinal Study (n = 2697; response rate: 67%). The first difference method was applied to estimate the association between these behaviours, implying that changes in the frequency of violence were regressed on changes in the frequency of drinking. Hence, the effects of time-invariant confounders were eliminated. Analyses were conducted for the whole sample, and for groups scoring low, medium and high on a short version of the STAXI anger suppression scale. Findings Changes in drinking were related positively and significantly to changes in violent behaviour, but the alcohol effect varied with the level of suppressed anger: it was strongest in the high-anger group (elasticity estimate = 0.053, P = 0.011) and weakest (and insignificant) in the low-anger group (elasticity estimate = 0.004, P = 0.806). Conclusions Alcohol use may be related causally to violence, but the effect of drinking is confined to individuals who are inclined to suppress their angry feelings. [source] Cannabis and crime: findings from a longitudinal studyADDICTION, Issue 1 2010Willy Pedersen ABSTRACT Aim To examine the association between cannabis use during adolescence and young adulthood, and subsequent criminal charges. Methods Data were obtained from the Young in Norway Longitudinal Study. A population-based sample (n = 1353) was followed from 13 to 27 years of age. Data were gathered on cannabis use, alcohol consumption and alcohol problems, and use of other illegal substances such as amphetamines, cocaine and opiates. In addition, extensive information on socio-demographic, family and personal factors was collected. This data set was linked to individual-level information from official Norwegian crime statistics. Findings We found robust associations between cannabis use and later registered criminal charges, both in adolescence and in young adulthood. These associations were adjusted for a range of confounding factors, such as family socio-economic background, parental support and monitoring, educational achievement and career, previous criminal charges, conduct problems and history of cohabitation and marriage. In separate models, we controlled for alcohol measures and for use of other illegal substances. After adjustment, we still found strong associations between cannabis use and later criminal charges. However, when eliminating all types of drug-specific charges from our models, we no longer observed any significant association with cannabis use. Conclusions The study suggests that cannabis use in adolescence and early adulthood may be associated with subsequent involvement in criminal activity. However, the bulk of this involvement seems to be related to various types of drug-specific crime. Thus, the association seems to rest on the fact that use, possession and distribution of drugs such as cannabis is illegal. The study strengthens concerns about the laws relating to the use, possession and distribution of cannabis. [source] Why Do the Young and Educated in LDCs Concentrate in Large Cities?ECONOMICA, Issue 285 2005Evidence from Migration Data Do the young and educated in LDCs have a greater preference to locate in big cities? If so, this may help to explain how cities spatially concentrate the educated and young, and why the rising share of these workers in many LDCs may contribute to city growth. This paper explores migration flows into and out of Egypt's three largest cities. We study whether the higher shares of such workers in cities arise because these workers perceive relatively greater benefits from living in cities, given relative urban/rural wage rates, or because the relative demand for these workers rises with city size. [source] Education and the Politics of Difference: Iris Young and the politics of educationEDUCATIONAL PHILOSOPHY AND THEORY, Issue 1 2006Avigail Eisenberg Abstract Three key contributions of Iris Young to democratic political theory, and three challenges that have arisen in response to Young's theory, are examined here in relation to education. First, Young has argued that oppression and domination, not distributive inequality, ought to guide discussions about justice. Second, eliminating oppression requires establishing a politics that welcomes difference by dismantling and reforming structures, processes, concepts and categories that sustain difference-blind, impartial, neutral, universal politics and policies. The infatuation with merit and standardized tests, both of which are central to measuring educational achievement, are chief amongst the targets in need of reform. Third, a politics of difference requires restructuring the division of labour and decision-making so as to include disadvantaged social groups but allow them to contribute without foregoing their particularities. The challenges that have arisen in response to Young's theory are first, that difference is merely another way of getting at inequality of resources or opportunities, and if it is not, then, second, a politics of difference values difference for the sake of difference rather than for the sake of alleviating social disadvantage. Third, in theory and in practice a politics that focuses on difference putatively jeopardizes a politics whose aim is to improve the redistribution of resources. [source] Smoking, nicotine dependence and mental health among young adults: a 13-year population-based longitudinal studyADDICTION, Issue 1 2009Willy Pedersen ABSTRACT Aims To investigate prospectively the associations between daily smoking and nicotine dependence and anxiety, depression and suicide attempts. Methods Data were from the Young in Norway Longitudinal Study. A population-based sample (n = 1501) was followed for 13 years from ages 13,27 years. Data were gathered on smoking patterns and nicotine dependence; and depression, anxiety and parasuicide. Extensive information on socio-demographic factors, parental and family conditions, parental rearing practices, educational career, conduct problems, alcohol problems and use of illegal substances was also collected. Results Young adults who were nicotine-dependent had clearly elevated rates of anxiety, depression and parasuicide. These rates declined after controlling for a previous history of mental health problems and potential confounding factors. After adjustment, nicotine dependence was still associated with anxiety, depression and parasuicide. There was also a significant association with later depression in the group of non-dependent daily smokers. Measures of reduced mental health did not predict later smoking initiation or the development of nicotine dependence. Conclusions Mental health was reduced more seriously in nicotine-dependent smokers than in non-dependent smokers. These findings are consistent with the hypothesis that smoking, in particular nicotine dependence, influences mental health. [source] Childbirth, abortion and subsequent substance use in young women: a population-based longitudinal studyADDICTION, Issue 12 2007Willy Pedersen ABSTRACT Aims To investigate the possible linkages between deliveries, abortions and subsequent nicotine dependence, alcohol problems and use of cannabis and other illegal drugs from the ages of 15,27 years. Methods Data were gathered as part of the Young in Norway Longitudinal Study, an 11-year follow-up of a representative sample of Norwegian adolescents and young adults. Design, setting and participants Information was obtained on (i) the history of childbirths and induced abortions for the participants between the ages of 15,27 years; (ii) measures of nicotine dependence, alcohol problems and use of cannabis and other illegal drugs; and (iii) socio-demographic, family and individual confounding factors. Results Those who had had an abortion had elevated rates of substance use and problems. Those who gave birth to a child had reduced rates of alcohol problems and cannabis use. These associations persisted after control for confounders. However, those women who still lived with the father of the aborted fetus were not at increased risk. Conclusions Abortion in women may, under some circumstances, be associated with increased risk of nicotine dependence, alcohol problems and use of cannabis and other illegal drugs. The birth of a child may reduce the use of some substances. [source] Diazepam Terminates Brief but Not Prolonged Seizures in Young, Naïve RatsEPILEPSIA, Issue 8 2003Howard P. Goodkin Summary: Purpose: Ample evidence exists from both clinical and animal studies that the success of benzodiazepine intervention during status epilepticus (SE) in the mature nervous system is inversely related to seizure duration. This relationship has not been well studied in the developing nervous system. Methods: The objective of this study was to investigate the relation of age and success of diazepam (DZP) treatment in the lithium-pilocarpine model of secondarily generalized seizure in the rat by using naïve rats of three age groups, roughly corresponding to the human ages of infancy (P15), adolescence (P20), and adult (P60). Results: In all age groups, the dosage of DZP that stopped the seizures at 5 min was not effective in terminating seizures at 60 min. This decline in efficacy was present as early as 15 min after seizure onset. Conclusions: These findings demonstrate that the inverse relation between the success of benzodiazepine intervention and seizure duration is observed in young as well as in adult rats and provide further evidence that intervention for SE should commence early. [source] Lactating Females Do Not Discriminate Between Their Own Young and Unrelated Pups in the Communally Breeding Rodent, Octodon degusETHOLOGY, Issue 9 2006Luis A. Ebensperger Females in numerous rodent species engage in communal nesting and breeding, in which they share one or more nests to rear their young. A potential cost of communal nesting and breeding is that mothers divert resources to unrelated offspring. One way mothers could avoid this cost is to recognize and favour their own young over unrelated offspring when allocating maternal effort. We assessed whether female degus (Octodon degus), a communally nesting and breeding caviomorph rodent, discriminate between their own and unrelated offspring during lactation. Female degus previously have been shown to distinguish between their own and unrelated pups when exposed to odours from both. We measured pup discrimination based on differences in the retrieval behaviour of females that were in early or intermediate lactation directed towards their own and unrelated offspring; offspring presented were of similar or different age. Before any event of pup retrieval, lactating females spent similar amounts of time and interacted to a similar extent with their own and unrelated pups. During pup retrieval, all lactating females transported both pups to the nest. Neither relatedness to pups, nor pup-age differences, influenced the order in which pups were retrieved to the nest. Dams waited similar amounts of time before retrieving the first pup when the first transported young was their own or unrelated. Likewise, females waited similar amounts of time before retrieving the second pup when the pup transported first was their own or unrelated. The time between first and second pup transport events was longer when dams were in early when compared with intermediate lactation, but only when pups were of similar age. All experimental subjects nursed unrelated pups after they were retrieved. Collectively, our results do not support the hypothesis that communally breeding female degus use their recognition ability to discriminate against unrelated offspring in favour of their own young. [source] Polymerase,, is up-regulated during the T,cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblastsEUROPEAN JOURNAL OF IMMUNOLOGY, Issue 5 2005Daniel Lucas Abstract Mammalian DNA polymerase,, (Pol,), preferentially expressed in secondary lymphoid organs, is shown here to be up-regulated in germinal centers after immunization. Alternative splicing appears to be part of Pol, regulation during an immune response. We generated Pol,-deficient mice that are viable and show no anatomical malformation or serious alteration in lymphoid populations, with the exception of an underrepresentation of the B,cell compartment. Young and aged homozygous Pol,,/, mice generated similar immune responses after immunization with the hapten (4-hydroxy-3-nitrophenyl)acetyl (NP) coupled to chicken gammaglobulin (CGG), compared with their wild-type littermates. Nonetheless, the kinetics of development of the centroblast population showed significant differences. Hypermutation analysis of the rearranged heavy chain intron region in centroblasts isolated from NP-CGG-immunized Pol,,/, mice showed a similar quantitative and qualitative somatic mutation spectrum, but a lower representation of heavily mutated clones. These results suggest that although it is not a critical partner, Pol, modulates the in vivo somatic hypermutation process. [source] Peripheral T,cell tolerance occurs early during spontaneous prostate cancer development and can be rescued by dendritic cell immunizationEUROPEAN JOURNAL OF IMMUNOLOGY, Issue 1 2005Elena Degl'Innocenti Abstract In the tumor-prone transgenic adenocarcinoma mouse prostate (TRAMP) mouse model we followed the fate of the immune response against the SV40 large T,antigen (Tag) selectively expressed in the prostate epithelium during the endogenous transformation from normal cells to tumors. Young (5,7-week-old) male TRAMP mice, despite a dim and patchy expression of Tag overlapping foci of mouse prostate intraepithelial neoplasia, displayed a strong Tag-specific cytotoxic T,lymphocyte (CTL) response after an intradermal injection of peptide-pulsed dendritic cells (DC). This response was weaker than the one found in vaccinated wild-type littermates, and was characterized by a reduced frequency and avidity of Tag-specific CTL. Early DC vaccination also subverted the profound state of peripheral tolerance typically found in TRAMP mice older than 9,10,weeks. The DC-induced CTL response indeed was still detectable in TRAMP mice of 16,weeks, and was associated with histology evidence of reduced disease progression. Our findings suggest that tumor antigens are handled as self antigens, and peripheral tolerance is associated with in situ antigen overexpression and cancer progression. Our data also support a relevant role for DC-based vaccines in controlling the induction of peripheral tolerance to tumor antigens. [source] Timing primate evolution: Lessons from the discordance between molecular and paleontological estimatesEVOLUTIONARY ANTHROPOLOGY, Issue 4 2008M. E. Steiper Abstract The molecular clock has become an increasingly important tool in evolutionary biology and biological anthropology. Nevertheless, a source of contention with respect to this method is the frequent discordance with fossil-based estimates of divergence times. The primate radiation is a case in point: Numerous studies have dated the major primate nodes (reviewed in Steiper and Young,1, 2) and there are many instances where molecular and fossil-based estimates of divergence times differ (Fig. 1). Some investigators have recently focused on phenomena such as stratigraphic dating, the stochastic nature of molecular time estimates, and other sources as potential biases in molecular clock estimates.3, 4 In this paper we do not focus on accuracy or statistical error; rather, we argue that discordance is a predictable phenomenon that provides valuable information about the tempo and mode of primate molecular and morphological evolution. Using this perspective, we reexamine the principal theoretical and methodological factors that lead to discordance between molecular and fossil estimates of the origins of taxa and discuss how a better understanding of these factors can help to improve our understanding of primate evolution. [source] Cardiovascular Response to Graded Lower Body Negative Pressure in Young and Elderly ManEXPERIMENTAL PHYSIOLOGY, Issue 3 2001R. van Hoeyweghen Lower body negative pressure (LBNP) reduces central venous pressure (CVP) and cardiac output. The elderly are reported to have a limited capacity to increase cardiac output by increasing heart rate (HR), are especially dependent on end diastolic volume to maintain stroke volume and therefore should be especially vulnerable to LBNP. The present study compared the effects of LBNP in the young and old. Stroke volume was assessed non-invasively as stroke distance (SD) by aortovelography. Two groups of healthy male volunteers were studied: eight young (29.7 ± 2.0 years, mean ± S.E.M.) and nine old (70.1 ± 0.9 years). LBNP was applied progressively at 17.5, 35 and 50 mmHg in 20 min steps, with measurements taken during each steady state. There were similar, significant, falls in CVP in both groups. SD fell significantly in both groups from respective control values of 24.8 ± 1.6 and 16.6 ± 0.9 cm to 12.5 ± 1.3 and 8.9 ± 0.4 cm at a LBNP of 50 mmHg. Although SD in the elderly was significantly lower than in the young, the LBNP-induced changes were not different between groups. Both groups produced similar significant increases in vascular resistance, HR, plasma vasopressin (AVP) and noradrenaline. Mean arterial blood pressure (MBP) and plasma adrenaline did not change significantly. Therefore healthy old men respond to LBNP in a similar manner to the young, although MBP and SD are regulated around different baselines in the two groups. [source] Save the Young,the Elderly Have Lived Their Lives: Ageism in Marriage and Family Therapy,FAMILY PROCESS, Issue 2 2000David C. Ivey Ph.D. The paucity of literature addressing mental health issues concerning geriatric populations represents the perpetuation of ageist practices and beliefs in the field of marriage and family therapy. The purpose of this study was to assess whether client age and clinical training relate to the evaluation of couples who present for conjoint therapy. Written vignettes describing two couples, one older and one younger, who report issues involving the absence of sexual intimacy, increased frequency of arguments, and increased use of alcohol were evaluated by practicing marriage and family therapists, therapists-in-training, and individuals with no clinical background. It was hypothesized that respondents' views would vary in connection with the age of the couple and with the three levels of participant training. Results indicate that client age and participant training are associated with perceptions of individual and couple functioning. Our findings suggest that the relational and mental health concerns experienced by elder couples are not perceived as seriously as are identical concerns experienced by younger couples. Contrary to our expectations the observed differences between views of the two age conditions did not significantly differ between levels of participant training. Training and experience in marriage and family therapy may not significantly mitigate vulnerability to age-discrepant views. [source] Reproductive strategies of Gammarus lacustris (Crustacea: Amphipoda) along an elevation gradientFUNCTIONAL ECOLOGY, Issue 4 2000Wilhelm F. M. Abstract 1.,The number of eggs, their size, mass and development time, and the starvation time of newly hatched young, was examined in four populations of Gammarus lacustris along an elevation gradient from prairie to alpine lakes (730 m to > 2300 m above sea level). Water temperature and ice-free season decreased with increasing altitude. 2.,Females in the alpine lake produced fewer but larger and heavier eggs than females in the prairie lake. Eggs produced by females in montane and subalpine lakes were intermediate in size, mass and number. Within populations, egg size was not related to the number of eggs or female size. 3.,The development time of eggs declined with an increase in incubation temperature. At all incubation temperatures, large eggs had a longer incubation time than small eggs. All eggs incubated at 4 °C failed to produce young. Young from large eggs were larger in size than young from small eggs. 4.,The starvation time of newly hatched young increased with decreasing temperature. However, slopes of regressions relating starvation time to temperature differed among populations. At 4 °C young from large eggs survived longer than young from small eggs. 5.,The high phenotypic plasticity in reproductive traits contributes to the success of G. lacustris in a wide range of aquatic habitats. It is predicted that in response to climate-induced warming, populations in currently cold montane and alpine lakes would shift their reproduction to produce more eggs of smaller size. However, the accurate prediction of the fate of populations between ecoregions will require knowledge of the extent to which these traits are under genetic control. [source] Functional alterations of liver innate immunity of mice with aging in response to CpG-oligodeoxynucleotide,HEPATOLOGY, Issue 5 2008Toshinobu Kawabata Immune functions of liver natural killer T (NKT) cells induced by the synthetic ligand ,-galactosylceramide enhanced age-dependently; hepatic injury and multiorgan dysfunction syndrome (MODS) induced by ligand-activated NKT cells were also enhanced. This study investigated how aging affects liver innate immunity after common bacteria DNA stimulation. Young (6 weeks) and old (50-60 weeks) C57BL/6 mice were injected with CpG oligodeoxynucleotides (CpG-ODN), and the functions of liver leukocytes were assessed. A CpG-ODN injection into the old mice remarkably increased tumor necrosis factor (TNF) production in Kupffer cells, and MODS and lethal shock were induced, both of which are rarely seen in young mice. Old Kupffer cells showed increased Toll-like receptor-9 expression, and CpG-ODN challenge augmented TNF receptor and Fas-L expression in liver NKT cells. Experiments using mice depleted of natural killer (NK) cells by anti-asialoGM1 antibody (Ab), perforin knockout mice, and mice pretreated with neutralizing interferon (IFN)-, Ab demonstrated the important role of liver NK cells in antitumor immunity. The production capacities of old mice for IFN-,, IFN-,, and perforin were much lower than those of young mice, and the CpG-induced antitumor cytotoxicity of liver NK cells lessened. Lethal shock and MODS greatly decreased in old mice depleted/deficient in TNF, FasL, or NKT cells. However, depletion of NK cells also decreased serum TNF levels and FasL expression of NKT cells, which resulted in improved hepatic injury and survival, suggesting that NK cells are indirectly involved in MODS/lethal shock induced by NKT cells. Neutralization of TNF did not reduce the CpG-induced antitumor effect in the liver. Conclusion: Hepatic injury and MODS mediated by NKT cells via the TNF and FasL-mediated pathway after CpG injection increased, but the antitumor activity of liver NK cells decreased with aging. (HEPATOLOGY 2008.) [source] Home and Identity: In Memory of Iris Marion YoungHYPATIA, Issue 3 2008ALLISON WEIR Drawing on Iris Marion Young's essay, "House and Home: Feminist Variations on a Theme,'' Weir argues for an alternative ideal of home that involves: (1) the risk of connection, and of sustaining relationship through conflict; (2) relational identities, constituted through both relations of power and relations of mutuality, love, and flourishing; (3) relational autonomy: freedom as the capacity to be in relationships one desires, and freedom as expansion of self in relationship; and (4) connection to past and future, through reinterpretive preservation and transformative identification. [source] Politics Improper: Iris Marion Young, Hannah Arendt, and the Power of PerformativityHYPATIA, Issue 4 2007JANE MONICA DREXLER This essay explores the value of oppositional, performative political action in the context of oppression, domination, and exclusionary political spheres. Rather than adopting Iris Marion Young's approach, Drexler turns to Hannah Arendt's theories of political action in order to emphasize the capacity of political action as action to intervene in and disrupt the constricting, politically devitalizing, necrophilic normalizations of proceduralism and routine, and thus to reorient the importance of contestatory action as enabling and enacting creativity, spontaneity, and resistance. [source] Dispersal and migration of juvenile African Black Oystercatchers Haematopus moquiniIBIS, Issue 3 2003Philip A. R. Hockey African Black Oystercatchers Haematopus moquini are sedentary as adults. However, colour-ringing of more than 700 juveniles has revealed complex post-fledging movements that vary geographically. Young from the western part of the breeding range either remain within 150 km of their natal site or migrate 1500,2000 km to one of five discrete nursery areas on the Namib Desert coast of central and northern Namibia, and southern Angola. These nurseries all lie north of the species' breeding range. We calculate that 36,46% of all juveniles born in South Africa migrate to nurseries. Birds return to their natal sites from nurseries at 2,3 years old, but never migrate again. Juveniles from the eastern part of the range undertake ,diffusion dispersal', regularly up to 1000 km, but these journeys mostly end within the breeding range, where there are no nurseries. Very few eastern birds reach nurseries. There is no evidence that movements of western birds are density-dependent responses to hatching date, but long-distance migrants are significantly heavier as chicks than are short-distance dispersers. We hypothesize that a genetic basis exists to these movements, possibly triggered by body condition, that could account not only for the highly dichotomous behaviour of western birds, but also for the intermediate behaviour of eastern birds. [source] Designing and Implementing an Information System for the Dental Office of Branckowitz & YoungACCOUNTING PERSPECTIVES, Issue 4 2008Alex Nikitkov ABSTRACT This case provides students with the opportunity to create a functional information system (IS) for a service company. The case facilitates a guided hands-on experience where students learn to analyze a business entity in the context of its environment; recognize what business processes comprise an entity's value chain; and develop, document, and implement a tailor-made IS to support the entity's operation. In order to keep the amount of development realistic and the system transparent for students, the case focuses on a small service company: a dental office. The case uses a resource,events,agents (REA) analytical framework for modeling and Microsoft Access for IS implementation. The case is structured modularly, enabling instructors to either explain material or demonstrate analysis/development of a segment of an IS in class and then challenge the students to complete the module's development following the instructor's example. Instructors have the flexibility to give students fewer (or additional) directions in developing the information system, depending on the students' backgrounds and abilities. Instructors also have a choice to limit the scope of the development and implementation to any number of four business processes. [source] | |||||||||||||||||||||||||||||||