Home About us Contact
|
Home About us Contact | ||
|
|
||
Wider Acceptance (wider + acceptance)
Selected AbstractsLongitudinal Diminution of Tumor Size for Basal Cell Carcinoma Suggests Shifting Referral Patterns for Mohs SurgeryDERMATOLOGIC SURGERY, Issue 1 2008ANDREW L. KAPLAN MD BACKGROUND The Mohs technique for removal of cutaneous malignancies offers tissue-sparing benefits compared with other treatment methods. With wider acceptance and availability of Mohs surgery, referral patterns may be shifting toward the treatment of smaller, lower-risk tumors. OBJECTIVE The objective was to examine whether referral patterns for basal cell carcinoma (BCC) at an academic Mohs surgery practice have shifted over recent years toward referral for smaller, lower risk tumors. METHODS A retrospective longitudinal comparison of tumor characteristics was performed for BCCs treated at our institution from a recent year (2004) and a past year (1996). Statistical analyses were used to identify differences in tumor size, distribution by anatomic site, and primary versus recurrent status. RESULTS Complete data were available for 603 BCCs treated in 1996 and 1,514 BCCs treated in 2004. A 24% decrease in preoperative tumor surface area was observed from 1996 (1.25 cm2) to 2004 (0.95 cm2). Tumors were twice as likely to be recurrent in 1996 (15.1%) than in 2004 (7.4%). There were no significant differences in the anatomic distribution of lesions in the years compared. CONCLUSIONS Findings at our institution suggest that in recent years, referral patterns have shifted toward a preference for Mohs surgery for the treatment of smaller, primary BCCs. This may be a result of increased awareness by the dermatologic and medical community of the numerous advantages of Mohs surgery and a greater appreciation of its tissue-sparing properties, which may result in less complex and more successful aesthetic reconstructions. [source] Estimating the monetary value of health care: lessons from environmental economicsHEALTH ECONOMICS, Issue 1 2003Nick Hanley In the recent past, considerable effort in health economics has been made on applying stated preference methods such as contingent valuation and choice experiments. Despite this increased use, there is still considerable scepticism concerning the value of these approaches. The application of contingent valuation in environmental economics has a long history and has been widely accepted. Whilst choice experiments were introduced to the environmental and health economics literature at a similar time, the wider acceptance of monetary measures of benefit in environmental economics has meant that they have also been more widely applied. The purpose of this paper is to identify some of the key issues and debates that have taken place in the environmental economics literature, summarise the state of the art with respect to these issues, and consider how health economists have addressed these issues. Important areas for future research in health economics are identified. Copyright © 2002 John Wiley & Sons, Ltd. [source] The International Quotidian Dialysis Registry: Annual report 2006HEMODIALYSIS INTERNATIONAL, Issue 3 2006Gihad E. NESRALLAH Abstract Interest in short daily and nocturnal hemodialysis (HD) regimens continues to grow worldwide. Despite growing optimism that these therapies will afford better patient outcomes over conventional HD, the current literature has not been viewed as sufficiently compelling to affect widespread implementation in most jurisdictions. Before these therapies can gain wider acceptance, larger and more rigorous studies will likely be needed. In June 2004, the Quotidian Dialysis Registry, based at the Lawson Health Research Institute at the University of Western Ontario, Canada, began recruiting patients across North America. By using an Internet-based data entry platform, patients from various centers worldwide will eventually be recruited, and studied prospectively. This paper constitutes the second annual update on patient and center recruitment, patient and treatment characteristics, and future directions for the registry. [source] Liquid membrane technology: fundamentals and review of its applicationsJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 1 2010M. F. San Román Abstract OVERVIEW: During the past two decades, liquid membrane technology has grown into an accepted unit operation for a wide variety of separations. The increase in the use of this technology owing to strict environmental regulations and legislation together with the wider acceptance of this technology in preference to conventional separation processes has led to a spectacular advance in membrane development, module configurations, applications, etc. IMPACT: Liquid membrane technology makes it possible to attain high selectivity as well as efficient use of energy and material relative to many other separation systems. However, in spite of the known advantages of liquid membranes, there are very few examples of industrial applications because of the problems associated with the stability of the liquid membrane. APPLICATIONS: Liquid membrane technology has found applications in the fields of chemical and pharmaceutical technology, biotechnology, food processing and environmental engineering. On the other hand, its use in other fields, such as in the case of hydrogen separation, the recovery of aroma compounds from fruits, the application of ionic liquids in the membrane formulation, etc., is increasing rapidly. Copyright © 2009 Society of Chemical Industry [source] Wear mechanisms in metal-on-metal bearings: The importance of tribochemical reaction layersJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 4 2010Markus A. Wimmer Abstract Metal-on-metal (MoM) bearings are at the forefront in hip resurfacing arthroplasty. Because of their good wear characteristics and design flexibility, MoM bearings are gaining wider acceptance with market share reaching nearly 10% worldwide. However, concerns remain regarding potential detrimental effects of metal particulates and ion release. Growing evidence is emerging that the local cell response is related to the amount of debris generated by these bearing couples. Thus, an urgent clinical need exists to delineate the mechanisms of debris generation to further reduce wear and its adverse effects. In this study, we investigated the microstructural and chemical composition of the tribochemical reaction layers forming at the contacting surfaces of metallic bearings during sliding motion. Using X-ray photoelectron spectroscopy and transmission electron microscopy with coupled energy dispersive X-ray and electron energy loss spectroscopy, we found that the tribolayers are nanocrystalline in structure, and that they incorporate organic material stemming from the synovial fluid. This process, which has been termed "mechanical mixing," changes the bearing surface of the uppermost 50 to 200 nm from pure metallic to an organic composite material. It hinders direct metal contact (thus preventing adhesion) and limits wear. This novel finding of a mechanically mixed zone of nanocrystalline metal and organic constituents provides the basis for understanding particle release and may help in identifying new strategies to reduce MoM wear. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:436,443, 2010 [source] Bilateral pulmonary edema after endoscopic sympathectomy in a patient with glucose-6-phosphate dehydrogenase deficiencyACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 1 2001C.-J. Lan Transaxillary endoscopic sympathectomy of thoracic ganglia (T2,T3) has recently gained wider acceptance as the treatment of choice for palmar hyperhidrosis. It requires one-lung ventilation to facilitate the surgery. One-lung ventilation, however, is not without complications, among which acute pulmonary edema has been reported. In this case report, we present a patient with palmar hyperhidrosis complicated by glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, who received bilateral endoscopic sympathectomy under alternate one-lung anesthesia, and developed acute pulmonary edema immediately after recruitment of the successive collapsed lung. The effects of hypoxemia, G-6-PD deficiency and sympathectomy might all add to the development of acute pulmonary edema secondary to reexpansion of each individual lung after alternate one-lung ventilation. The possibilities of the inferred causes are herein discussed. [source] The impact of medical technology on office workflowORTHODONTICS & CRANIOFACIAL RESEARCH, Issue 2003SP McEvoy Abstract Author, McEvoy SP Digital technologies are gaining wider acceptance within the medical and dental professions. The lure of increased productivity and improved quality entice practices to adapt. These systems are beginning to have a profound impact on the workflows within the practice, as well as putting new demands on existing resources. To successfully implement a new technology within your practice, you must look beyond advertising and discover the real requirements of the system. Vendors rarely try to help beyond the sale and installation of their equipment, nor do they consider how their product might require you to modify the way you and your staff work. Acquiring the necessary knowledge through self-education, a consultant, or (preferably) a combination of the two is the best way to integrate a new technology with your practice. [source] An Application of Six Sigma to Reduce WasteQUALITY AND RELIABILITY ENGINEERING INTERNATIONAL, Issue 6 2005Ricardo Bañuelas Abstract Six Sigma has been considered a powerful business strategy that employs a well-structured continuous improvement methodology to reduce process variability and drive out waste within the business processes using effective application of statistical tools and techniques. Although there is a wider acceptance of Six Sigma in many organizations today, there appears to be virtually no in-depth case study of Six Sigma in the existing literature. This involves how the Six Sigma methodology has been used, how Six Sigma tools and techniques have been applied and how the benefits have been generated. This paper presents a case study illustrating the effective use of Six Sigma to reduce waste in a coating process. It describes in detail how the project was selected and how the Six Sigma methodology was applied. It also shows how various tools and techniques within the Six Sigma methodology have been employed to achieve substantial financial benefits. Copyright © 2005 John Wiley & Sons, Ltd. [source] Radioiodine treatment for benign thyroid diseasesCLINICAL ENDOCRINOLOGY, Issue 6 2007Anthony P. Weetman Summary Radioiodine has been in use for over 60 years as a treatment for hyperthyroidism. Major changes in clinical practice have occurred with the realization that accurate dosimetry is incapable of avoiding the risks of hypothyroidism, while more accurate assessment of the risks of other adverse effects of radioiodine such as ophthalmopathy and carcinogenesis have become available. More is also known of the potential for pretreatment with an antithyroid drug to affect the outcome of radioiodine treatment. However, we are still uncertain of the benefits of radioiodine treatment in subclinical hyperthyroidism. During the last two decades there has been wider acceptance of radioiodine as a safe and effective therapy for benign, nontoxic goitre, coupled with waning enthusiasm for the use of levothyroxine, as the risks and benefits of this option have become more apparent. The use of recombinant TSH offers the prospect that radioiodine treatment of nontoxic goitre can be simplified and improved, although more studies of this strategy are urgently required. [source] | ||||||||||