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Selected AbstractsAPEX-Map: a parameterized scalable memory access probe for high-performance computing systems,CONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 17 2007Erich Strohmaier Abstract The memory wall between the peak performance of microprocessors and their memory performance has become the prominent performance bottleneck for many scientific application codes. New benchmarks measuring data access speeds locally and globally in a variety of different ways are needed to explore the ever increasing diversity of architectures for high-performance computing. In this paper, we introduce a novel benchmark, APEX-Map, which focuses on global data movement and measures how fast global data can be fed into computational units. APEX-Map is a parameterized, synthetic performance probe and integrates concepts for temporal and spatial locality into its design. Our first parallel implementation in MPI and various results obtained with it are discussed in detail. By measuring the APEX-Map performance with parameter sweeps for a whole range of temporal and spatial localities performance surfaces can be generated. These surfaces are ideally suited to study the characteristics of the computational platforms and are useful for performance comparison. Results on a global-memory vector platform and distributed-memory superscalar platforms clearly reflect the design differences between these different architectures. Published in 2007 by John Wiley & Sons, Ltd. [source] Constructing Vulnerability: The Historical, Natural and Social Generation of Flooding in Metropolitan ManilaDISASTERS, Issue 3 2003Greg Bankoff Flooding is not a recent hazard in the Philippines but one that has occurred throughout the recorded history of the archipelago. On the one hand, it is related to a wider global ecological crisis to do with climatic change and rising sea levels but on the other hand, it is also the effect of more localised human activities. A whole range of socio-economic factors such as land use practices, living standards and policy responses are increasingly influencing the frequency of natural hazards such as floods and the corresponding occurrence of disasters. In particular, the reason why flooding has come to pose such a pervasive risk to the residents of metropolitan Manila has its basis in a complex mix of inter-relating factors that emphasise how the nature of vulnerability is constructed through the lack of mutuality between environment and human activity over time. This paper examines three aspects of this flooding: first, the importance of an historical approach in understanding how hazards are generated; second, the degree of interplay between environment and society in creating risk; and third, the manner in which vulnerability is a complex construction. [source] Capital Versus the Districts: A Tale of One Multinational Company's Attempt to Disembed ItselfECONOMIC GEOGRAPHY, Issue 2 2004N. A. Phelps Abstract: The process of international economic integration in which multinational enterprises (MNEs) play a significant orchestrating role is a contradictory one of a space of flows, on the one hand, and a space of places, on the other hand. It is this contradiction that produces a variegated landscape of relations within and among MNEs and a whole range of territorially rooted organizations and institutions. As a result, interest in global production networks, as part of a broader relational turn in economic geography, has sought to highlight and uncover these webs of relations within which MNEs are embedded. In reviewing this literature, we emphasize the economic imperatives underlying such relations or, rather, their political-economic nature and the discontinuities in industrial restructuring they can produce. We then present an empirical illustration of these points and some of the key concerns within the literature on global production networks. We consider a recent round of restructuring by Black & Decker Corporation, focusing on the politico-economic ramifications of closing one of two European factories. Our reading of the literature, coupled with our empirical findings, suggests the continuing tendency for international integration as a space of flows to eclipse the coherence of places. Localized points of resistance can moderate the powers exercised by MNEs internally and across a network of organizations, although there are limits to the transferability of such tactics of resistance. [source] Does Italy's plight threaten European Monetary Union?ECONOMIC OUTLOOK, Issue 3 2005Article first published online: 27 JUL 200 The Italian economy is in a mess. GDP is expected to contract by 0.6% this year and the budget deficit is heading towards 4% of GDP , it is hard to see a way out of the mire. And after the rejection of the European constitution in France and the Netherlands, questions are being asked about the very future of the European project. With Italy fundamentally uncompetitive across a whole range of both price and non-prices measures, and with an industrial structure ill-equipped to deal with the challenges of globalisation, Italy's long-term membership of the Euro is being debated. This article by Keith Church sets out Italy's problems and argues that, if the economy stagnates for a prolonged period, pressure to leave EMU will become irresistible. This can be avoided if the government finally implements structural reforms instead of continually ,muddling through'. At the same time, the ECB needs to realise the urgency of the current situation and start to show greater flexibility. [source] Has Finance Made the World Riskier?EUROPEAN FINANCIAL MANAGEMENT, Issue 4 2006Raghuram G. Rajan G20; G21; G22 Abstract Developments in the financial sector have led to an expansion in its ability to spread risks. The increase in the risk bearing capacity of economies, as well as in actual risk taking, has led to a range of financial transactions that hitherto were not possible, and has created much greater access to finance for firms and households. On net, this has made the world much better off. Concurrently, however, we have also seen the emergence of a whole range of intermediaries, whose size and appetite for risk may expand over the cycle. Not only can these intermediaries accentuate real fluctuations, they can also leave themselves exposed to certain small probability risks that their own collective behaviour makes more likely. As a result, under some conditions, economies may be more exposed to financial-sector-induced turmoil than in the past. The paper discusses the implications for monetary policy and prudential supervision. In particular, it suggests market-friendly policies that would reduce the incentive of intermediary managers to take excessive risk. [source] Incorporation of Aluminium and Iron into the Zeolite MCM-58EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 6 2005Gabriela Ko Abstract The hydrothermal synthesis of zeolite MCM-58 is investigated with N -benzylquinuclidinium bromide as a structure-directing agent in order to isomorphously substitute aluminium or iron for silicon. Al-MCM-58 was synthesised in a wide range of nSi/nAl ratios (from 19 to 56), and Fe-MCM-58 was successfully prepared in a narrower range of nSi/nFe ratios (from 18 to 36). The obtained products were characterised by XRD, SEM, 27Al MAS NMR, 29Si MAS NMR, FTIR, and ESR spectroscopy. Two different calcination procedures, viz. in a stream of nitrogen and air or in a stream of ammonia, were used in order to modify the acid sites in the zeolite. FTIR spectroscopy before and after the adsorption of [D3]acetonitrile and pyridine was employed to determine the concentration and type of the acid sites. The acid forms of Al(Fe)-MCM-58 are characterised by the vibrations of bridging Si,OH,Al(Fe) groups at 3628 cm,1 and 3564 cm,1 (Al-MCM-58) or 3646 cm,1 and 3520 cm,1 (Fe-MCM-58). The acid sites of both zeolites Al-MCM-58 and Fe-MCM-58 are accessible for [D3]acetonitrile and pyridine, and all materials contain substantial numbers of Lewis sites (Al-MCM-58: 50,% of the total acid sites; Fe-MCM-58: 90,%) over the whole range of nSi/nAl (nSi/nFe) ratios studied. Only a small increase in the concentration of Brønsted acid sites was achieved after calcination of the as-synthesised samples in a flow of ammonia. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source] Thalidomide, BSE and the single market: An historical-institutionalist approach to regulatory regimes in the European UnionEUROPEAN JOURNAL OF POLITICAL RESEARCH, Issue 1 2007SEBASTIAN KRAPOHL In the last decade, the regulatory regime for pharmaceuticals has functioned without raising public concerns. The establishment of a European agency for pharmaceuticals in the early 1990s has been evaluated positively by both producers and consumers, and there have been no large scandals so far. At the same time, the food sector was subject to a whole range of crises, of which the BSE scandal was certainly the most significant one. In reaction to this, the regulatory regime for foodstuffs was reformed by setting up the European Food Safety Agency in 2002. This article adopts an historical-institutionalist approach, and thus tries to give an explanation for the striking differences between the two regulatory regimes. Accordingly, the development of supranational regulatory regimes is distinguished by two critical junctures: a crisis of consumer confidence and the establishment of a single market. It is crucial which of these occurred first. If a crisis of consumer confidence leads to the establishment of national regulatory authorities, these authorities act as stakeholders, which could be an obstacle for harmonization, but also ensures a necessary commitment to health and consumer protection once a single market is set up. If national regulatory authorities are missing, it might be easier to set up a single market, but a regulatory deficit is more likely to occur and, in case of a crisis, the whole regulatory regime has to be established at the supranational level. [source] Moving up, moving down: Political careers across territorial levelsEUROPEAN JOURNAL OF POLITICAL RESEARCH, Issue 2 2003Klaus Stolz In the sparse literature on political careers in federal systems, regional positions are often seen as mere stepping stones on the way to federal office. But are they really? The recent professionalization of state politics in federal systems and the regionalization of former unitary states point to the strengthening of the regional level as a career arena in its own right. Could this lead to the emergence of a regional political class with a set of career interests distinct from those of national politicians? This article takes a first, comparative look at current patterns of career movements between regional and national parliaments in a wide range of federal and newly regionalized systems. The study shows that, contrary to general belief, the number of deputies actually moving from the regional to federal level is generally relatively low. While some cases show fairly integrated career structures, others exhibit a pattern of career development in which state or regional office functions as the main focus of political careers. The territorial structure of the political class is dependent upon a whole range of social, cultural and institutional factors. At the same time, it is also an important factor in the mechanics and institutional development of each federal system in question. [source] Mitigation of the produced voltages in AC overhead power-lines/pipelines parallelism during power frequency and lightning conditionsEUROPEAN TRANSACTIONS ON ELECTRICAL POWER, Issue 4 2005I. A. Metwally Abstract This paper presents a theoretical simulation for a pipeline running in parallel to AC overhead power lines using the ,CONCEPT II' package. This package is based on the method of moment combined with a transmission-line model. A 1,km long, 132,kV, three-phase, double-circuit transmission line, and a 2,km long, 40,cm diameter, 1,m high above-ground pipeline are modelled. Extra shielding wires (ESW) under the phase conductors are investigated. Produced voltages in the pipeline are computed under steady-state power frequency (50,Hz) as well as under direct and indirect lightning strikes to the power line. Different current waveforms are simulated to cover the whole range of those of the anticipated lightning. Under lightning strikes, the voltages across line insulators are computed, too. The results reveal that the ESW give many advantages; namely, (1) reducing the power-frequency electric and magnetic fields at the ground level to meet the regularity limits, (2) improving the shielding effectiveness during lightning strikes by reducing the insulator voltages, (3) mitigating the induced voltages in any metallic structure near the power lines, e.g., pipelines, and (4) using them as optical ground wires for telecommunication purposes, where the probability of lightning strikes to such ESW is much lower than that for the normally used grounding wire(s) at the tower top. Copyright © 2005 John Wiley & Sons, Ltd. [source] Characterization of Ti-Ta Alloys Synthesized by Cold Crucible Levitation Melting,ADVANCED ENGINEERING MATERIALS, Issue 8 2008D.-M. Gordin Ti-Ta alloys are potentially interesting for many applications including chemistry industries, marine environment and biomedical devices. In this study, the Ti-Ta alloys were synthesized by cold crucible levitation melting (CCLM) in the whole range of composition. The different microstructures were characterized by X-ray diffraction and optical microscopy, the ,-transus was detected by electrical resistivity, the mechanical properties were evaluated by compression tests and microhardness measurements and the electrochemical behavior was carried out in Ringer's solution. [source] PERSPECTIVE: THE SIZE-COMPLEXITY RULEEVOLUTION, Issue 9 2004J. T. Bonner Abstract It is widely accepted that bigger entities have a greater division of labor than smaller ones and this is reflected in the fact that larger multicellular organisms have a corresponding increase in the number of their cell types. This rule is examined in some detail from very small organisms to large animals, and plants, and societies. Compared to other size-related rules, the size-complexity rule is relatively rough and approximate, yet clearly it holds throughout the whole range of living organisms, as well as for societies. The relationship between size and complexity is analyzed by examining the effects of size increase and decrease: size increase requires an increase in complexity, whereas size decrease permits, and sometimes requires, a decrease in complexity. Conversely, an increase or decrease in complexity permits, but does not require changes in size. An especially compelling argument for the close relation between size and complexity can be found in size quorum sensing in very small multicellular organisms. [source] Quo vadis neurohypophysial hormone research?EXPERIMENTAL PHYSIOLOGY, Issue 2000Alison J. Douglas Here we highlight just a few of the outstanding questions in the field of neurohypophysial hormones that we envisage will be addressed successfully in the new millennium. To begin, we focus on the regulation of receptors. Despite intensive investigation with new drugs, molecular modelling and transgenic models, the determinants of receptor selectivity remain elusive; there may even be more vasopressin or oxytocin receptor subtypes to be discovered. We discuss the controversy over the interesting studies that indicate modulation of oxytocin receptor-binding by steroids. Oxytocin and vasopressin release and action in the brain are discussed from several aspects. Dendritically released oxytocin acting locally is important for the milk ejection reflex, and similarly released vasopressin is important in regulating patterning of vasopressin neurone activity. Such dendritically released oxytocin and vasopressin is likely to be important in paracrine modulation of neural circuitry involved in neuroendocrine control, and for a range of behaviours. Is it possible that the whole range of behaviours that comprise ,social' (or ,anti-social') or ,maternal' behaviour can be engineered by modifying the expression of just these one or two peptides and their receptors? However, whether gene expression and knockout approaches will answer all the open questions about the real functions of oxytocin and vasopressin remains to be shown. [source] Influence of inclusion size on S-N curve characteristics of high-strength steels in the giga-cycle fatigue regimeFATIGUE & FRACTURE OF ENGINEERING MATERIALS AND STRUCTURES, Issue 8 2009L. T. LU ABSTRACT Fatigue fracture of high-strength steels often occurs from small defect on the surface of a material or from non-metallic inclusion in the subsurface zone of a material. Under rotating bending loading, the S-N curve of high-strength steels consists of two curves corresponding to surface defect-induced fracture and internal inclusion-induced fracture. The surface defect-induced fracture occurs at high stress amplitude levels and low cycles. However, the subsurface inclusion-induced fracture occurs at low stress amplitude levels and high-cycle region of more than 106 cycles (giga-cycle fatigue life). There is a definite stress range in the S-N curve obtained from the rotating bending, where the crack initiation site changes from surface to subsurface, giving a stepwise S-N curve or a duplex S-N curve. On the other hand, under cyclic axial loading, the S-N curve of high-strength steels displays a continuous decline and surface defect-induced or internal inclusion-induced fracture occur in the whole range of amplitudes. In this paper, influence factors on S-N curve characteristics of high-strength steels, including size of inclusions and the stress gradient of bending fatigue, were investigated for rotating bending and cyclic axial loading in the giga-cycle fatigue regime. Then, based on the estimated subsurface crack growth rate from the S-N data, effect of inclusion size on the dispersion of fatigue life was explained, and it was clarified that the shape of S-N curve for subsurface inclusion-induced fracture depends on the inclusion size. [source] Biofilms in chronic bacterial prostatitis (NIH-II) and in prostatic calcificationsFEMS IMMUNOLOGY & MEDICAL MICROBIOLOGY, Issue 3 2010Sandra Mazzoli Abstract The prevalence of inflammatory conditions of the prostate gland is increasing. In Italy, there is a high incidence of prostatitis (13.3%), also accompanied by prostatic calcifications. Cat NIH-II chronic bacterial prostatitis (CBPs) are the most frequent. Their aetiology theoretically involves the whole range of bacterial species that are able to form biofilms and infect prostate cells. The aim of our study was to isolate potential biofilm-producing bacteria from CBP patients, to evaluate their ability to produce in vitro biofilms, and to characterize intraprostatic bacteria and prostatic calcifications using scanning electron microscopy. The 150 clinical bacterial strains isolated from chronic prostatitis NIH-II patients were: 50 Enterococcus faecalis; 50 Staphylococcus spp.; 30 Escherichia coli; 20 gram-negative miscellanea. Quantitative assay of biofilm production and adhesion was performed according to the classic Christensen microwell assay. Isolates were classified as nonproducers, weak, moderate or strong producers. The majority of E. coli, gram-negative bacteria, Staphylococci and Enterococci strains were strong or medium producers: 63,30%, 75,15%, 46,36%, and 58,14%, respectively. Prostatic calcifications consisted of bacteria-like forms similar to the species isolated from biological materials and calcifications of patients. Our study proves, for the first time, that bacterial strains able to produce biofilms consistently are present in CBP. Additionally, prostatic calcifications are biofilm-related. [source] Fluid-induced seismicity: Pressure diffusion and hydraulic fracturingGEOPHYSICAL PROSPECTING, Issue 2 2009S.A. Shapiro ABSTRACT Borehole fluid injections are common for the development of hydrocarbon and geothermic reservoirs. Often they induce numerous microearthquakes. Spatio-temporal dynamics of such induced microseismic clouds can be used to characterize reservoirs. However, a fluid-induced seismicity can be caused by a wide range of processes. Here we show that linear pore pressure relaxation and a hydraulic fracturing are two asymptotic end members of a set of non-linear diffusional phenomena responsible for seismicity triggering. To account for the whole range of processes we propose a rather general non-linear diffusional equation describing the pore pressure evolution. This equation takes into account a possibly strong enhancement of the medium permeability. Both linear pore pressure relaxation and hydraulic fracturing can be obtained as special limiting cases of this equation. From this equation we derive the triggering front of fluid induced seismicity, which is valid in the general case of non-linear pore pressure diffusion. We demonstrate corresponding seismicity signatures on different case studies. [source] An emotive subject: insights from social, voluntary and healthcare professionals into the feelings of family carers for people with mental health problems,HEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 2 2009Ben Gray BA PhD Senior Research Fellow CCCU Abstract Caring for people with mental health problems can generate a whole range of positive and negative emotions, including fear, disbelief, guilt and chaos as well as a sense of purpose, pride and achievement. This paper explores the emotions of family carers from the perspectives of social, voluntary and healthcare professionals. Sixty-five participants were interviewed, the sample included directors, managers and senior staff from social, voluntary and healthcare organisations. Participants were encouraged to talk in detail about their understanding of the emotions of family carers. Findings highlight a rich understanding of the broad spectrum of carer emotions and the huge emotional adjustments that are often involved. Diagnosis was seen to be imbued with negative emotions, such as fear, anger and denial. However, feelings of hopelessness and desolation were often counterbalanced by feelings of hope, satisfaction and the emotional rewards of caring for a loved one. Participants noted a clear lack of emotional support for family carers, with accompanying feelings of marginalisation, particularly during transitions and especially involving young carers as well as ethnic minorities. By way of contrast, carer support groups were suggested by professionals to be a holistic, effective and economical way of meeting carers' emotional needs. This paper explores the challenge of family carer emotions from the perspective of managers and practitioners and draws out implications for research, policy and practice. [source] Valuing health: a new proposalHEALTH ECONOMICS, Issue 3 2010Daniel M. Hausman Abstract After criticizing existing systems of health measurement for their unargued commitment to evaluating health states in terms of preferences or well-being, this essay argues that public rather than private values of health states should help guide the allocation of health-related resources. Private evaluation of health states is relative to a prior individual choice of specific activities and goals, while public evaluation is relative to the whole range of important activities and goals. Public evaluation is concerned with securing a wide range of choices as well as with success given one's choice. A reasonable simplification from the public perspective is to focus on just two features of health states: the subjective feelings attached to health states and the limitations that health states imply on the range of important activities that individuals can pursue. Focusing on just these two dimensions permits the construction of a parsimonious classification of health states with regard to what matters most from the public perspective. This classification, which resembles those in the HALex and the Rosser and Kind Disability and Distress Index, might best be built on top of existing health-state classifications, by mapping the health states they define to activity-limitation/feeling pairs. To assign values to these pairs, I propose relying on deliberative groups to make comparisons among the pairs with respect to the relation ,is a more serious limitation on the range of objectives and good lives available to members of the population'. A ranking according to this property, is not a preference ranking, because it is not a ranking in terms of everything that matters to individuals. Working back from the weights attached to the activity-limitation/feeling pairs, one can impute weights for the health states in other classification systems that were mapped to those pairs. If those weights coincide roughly with current weights, then one legitimizes current weights and provides a vehicle for their public discussion and possible revision. If those weights do not coincide, then one has both an argument for revising current views of the cost effectiveness of treatments and policies and a method to carry out such a revision. Copyright © 2009 John Wiley & Sons, Ltd. [source] Quality safeguards and regulation of online pharmaciesHEALTH ECONOMICS, Issue 4 2004Benito ArruñadaArticle first published online: 25 JUN 200 Abstract Using econometric evidence, this article confirms that distribution of medicines online is split into two market segments of very diverse quality, and identifies the factors that drive quality and quality assurance in this activity. Unlike fraudulent, ,rogue,' websites, which offer scant guarantees and usually sell just a few medicines without prescription, online pharmacies offering insurance coverage and linked to conventional pharmacies typically sell a whole range of drugs, require third-party medical prescriptions and provide abundant information to patients. It is shown that, where online pharmacies are allowed to act legally, market forces enhance quality, as private insurers require professional standards, and specialized third parties make a business of certifying them. Furthermore, older online pharmacies and those running conventional operations offer higher quality, probably because of reputational investments. Overall, this evidence supports licensing online pharmacies, especially considering that prohibiting them is ineffective against fraudulent sites. Copyright © 2003 John Wiley & Sons, Ltd. [source] Effect of halothane on type 2 immobility-related hippocampal theta field activity and theta-on/theta-off cell dischargesHIPPOCAMPUS, Issue 1 2003Brian H. Bland Abstract Rats were studied in acute and chronic (freely moving) recording conditions during exposure to different levels of the volatile anesthetic halothane, in order to assess effects on hippocampal theta field activity in the chronic condition and on theta-related cellular discharges in the acute condition. Previous work has shown that the generation of hippocampal type 2 theta depends on the coactivation of cholinergic and GABAergic inputs from the medial septum. Based on these data and recent findings that halothane acts on interneuron GABAA receptors, we predicted that exposure of rats to subanesthetic levels would result in the induction of type 2 theta field activity. In the chronic condition, exposure to subanesthetic levels of halothane (0.5,1.0 vol %) was found to induce theta field activity during periods of immobility (type 2 theta) with a mean increase of 39% in amplitude (mV) compared to control levels during movement. The total percentage of signal power (V2) associated with peak theta frequencies (80% compared to control levels of 47%) was also increased by halothane. Over the whole range of administered halothane concentrations, theta field frequency progressively declined from a mean peak frequency of 6.5 ± 0.8 Hz at 0.5 vol % halothane to a mean peak frequency of 4.0 ± 1.8 Hz at 2.0 vol % halothane. Subsequent administration of a muscarinic cholinergic antagonist, atropine sulfate, selectively abolished all type 2 immobility-related theta field activity, while type 1 movement-related theta was still intact. At anesthetic levels (1.5,2.0 vol %) in acute experiments, hippocampal field activity spontaneously cycled between theta and large-amplitude irregular activity. Analysis of depth profiles in four experiments revealed they were identical to those previously described for rats under urethane anesthesia conditions. In addition, the discharge properties of 31 theta-related cells, classified as tonic and phasic theta-on and tonic and phasic theta-off cells, did not differ significantly from those described previously in rats anesthetized with urethane. These data provide further support for an involvement of GABAA receptors in the generation of hippocampal theta. Hippocampus 2003;13:38,47. © 2003 Wiley-Liss, Inc. [source] Energy-Level Alignment at Organic/Metal and Organic/Organic InterfacesADVANCED MATERIALS, Issue 14-15 2009Slawomir Braun Abstract In this Review, we summarize recent work on modeling of organic/metal and organic/organic interfaces. Some of the models discussed have a semiempirical approach, that is, experimentally derived values are used in combination with theory, and others rely completely of calculations. The models are categorized according to the types of interfaces they apply to, and the strength of the interaction at the interface has been used as the main factor. We explain the basics of the models, their use, and give examples on how the models correlate with experimental results. We stress that given the complexity of organic/metal and organic/organic interface formation, it is crucial to know the exact way in which the interface was formed before choosing the model that is applicable, as none of the models presented covers the whole range of interface interaction strengths (weak physisorption to strong chemisorption). [source] MR linear contact detection algorithmINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING, Issue 1 2006A. Munjiza Abstract Large-scale discrete element simulations, as well as a whole range of related problems, involve contact of a large number of separate bodies and an efficient and robust contact detection algorithm is necessary. There has been a number of contact detection algorithms with total detection time proportional to N ln(N) (where N is the total number of separate bodies) reported in the past. In more recent years algorithms with total CPU time proportional to N have been developed. In this work, a novel contact detection algorithm with total detection time proportional to N is proposed. The performance of the algorithm is not influenced by packing density, while memory requirements are insignificant. The algorithm is applicable to systems comprising bodies of a similar size. The algorithm is named MR (Munjiza,Rougier: Munjiza devised the algorithm, Rougier implemented it). In the second part of the paper the algorithm is extended to particles of different sizes. The new algorithm is called MMR (multi-step MR) algorithm. Copyright © 2005 John Wiley & Sons, Ltd. [source] Respiratory complications of obesityINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 6 2004A.S. Jubber Summary Obesity is known to be a major risk factor of a whole range of cardiovascular, metabolic and respiratory disorders. It has been recognised that the pattern of regional fat distribution plays an important role in the pre-disposition of obese subjects to certain obesity-related complications. Derangement of parameters of lung function is determined to a large extent by the quantity and distribution of excess body fat with its potential to interfere with the mechanics of pulmonary physiology. Clinical, laboratory and epidemiological observations have established links between obesity and several breathing problems including obstructive sleep apnoea, obesity hypoventilation syndrome and asthma. However, in many respects, the pathophysiology of these links is not fully explored. In this article, the impact of obesity on pulmonary physiology and its association with the above-mentioned clinical conditions is discussed. [source] Performance enhancement of gas turbines by inlet air-cooling in hot and humid climatesINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 10 2006Majed M. Alhazmy Abstract In this paper, a model to study the effect of inlet air-cooling on gas turbines power and efficiency is developed for two different cooling techniques, direct mechanical refrigeration and an evaporative water spray cooler. Energy analysis is used to present the performance improvement in terms of power gain ratio and thermal efficiency change factors. Relationships are derived for an open gas turbine cycle with irreversible compression and expansion processes coupled to air-cooling systems. The obtained results show that the power and efficiency improvements are functions of the ambient conditions and the gas turbine pressure ratio. The performance improvement is calculated for, ambient temperatures from 30 to 50°C, the whole range of humidity ratio (10,100%) and pressure ratio from 8 to 12. For direct mechanical refrigeration air-cooling, the power improvement is associated with appreciable drop in the thermal efficiency. The maximum power gain can be obtained if the air temperature is reduced to its lowest limit that is the refrigerant evaporation temperature plus the evaporator design temperature difference. Water spray cooling process is sensitive to the ambient relative humidity and is suitable for dry air conditions. The power gain and efficiency enhancement are limited by the wet bulb temperature. The performance of spray evaporative cooler is presented in a dimensionless working graph. The daily performance of the cooling methods is examined for an ABB-11D5 gas turbine operating under the hot humid conditions of Jeddah, Saudi Arabia. The results indicate that the direct mechanical refrigeration increased the daily power output by 6.77% versus 2.57% for the spray air-cooling. Copyright © 2005 John Wiley & Sons, Ltd. [source] Reconciling situational social psychology with virtue ethicsINTERNATIONAL JOURNAL OF MANAGEMENT REVIEWS, Issue 3 2008Surendra Arjoon For the past four decades, debate has occurred in respect of situational social psychology and virtue ethics. This paper attempts to reconcile this debate. Situationists propose a fragmentation theory of character (each person has a whole range of dispositions, each of which has a restricted situational application) and do not subscribe to a regularity theory of character (behaviour is regulated by long-term dispositions). In order to support this view, they cite a number of experiments. It is proposed that the substantive claims made by situationist social psychologists, for the most part, do not undermine or disagree with an Aristotelian virtue ethics perspective, but stem from a misunderstanding of concepts of moral character, faulty conclusions and generalizations in respect of experimental results. Situationists take a narrow view of character and morality. Evidence from organizational behaviour and managerial research literature supports the view that both situational (organizational) features and inner characteristics (including virtues) are powerful influences and determinants of morally upright and morally deviant behaviour. The role of practical judgement in bridging these views is discussed. As a way forward in reconciling situational social psychology with virtue ethics, the paper proposes an Aristotelian,Thomistic framework to overcome some of the problems associated with inadequate regulative ideals in building a normative moral theory. [source] Emotional intelligence, its measurement and implications for the workplaceINTERNATIONAL JOURNAL OF MANAGEMENT REVIEWS, Issue 2 2008Susan Cartwright The concept of emotional intelligence (EI) has attracted a huge amount of interest from both academics and practitioners and has become linked to a whole range of outcomes, including career success, life satisfaction and health. Yet the concept itself and the way in which it is measured continue to fuel considerable debate. This paper takes a critical review of the methodologies and robustness of the validation and application studies that have used EI measures. In addition, the links between EI and other related theoretical perspectives such as emotional labour are considered. [source] Highly Functionalised Enantiopure 4-Hydroxypyridine Derivatives by a Versatile Three-Component SynthesisADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7-8 2009Christian Eidamshaus Abstract The scope of a novel alkoxyallene-based pyridine synthesis was expanded to enantiopure carboxylic acids and nitriles as starting materials. The enantiomeric purity of the chiral ,-secondary carboxylic acids and nitriles was completely preserved during this reaction sequence thus allowing the one-pot preparation of a whole range of 4-hydroxypyridines or their 4-pyridinone tautomers in good yields. [source] Nonstationary spatio-temporal small rodent dynamics: evidence from long-term Norwegian fox bounty dataJOURNAL OF ANIMAL ECOLOGY, Issue 3 2009John-André Henden Summary 1The geographical pattern in Fennoscandian small rodent population dynamics with a southern noncyclic and a northern cyclic region, and with latitudinal gradients in density-dependent structure, cycle period length and spatial synchrony within the northern cyclic region, has been widely publicized and interpreted in the ecological literature. However, the time-series data on which these inferences have been established are relatively short and originate from a specific time period (mostly around 1970,90). Hence, it can be questioned whether the geographical population dynamics patterns are consistent over time (i.e. whether they are stationary). 2Here we analyse an almost century long (1880,1976) panel of fox bounty time series including 18 counties of Norway, thus spanning the whole range of latitudes of Fennoscandia (i.e. 15 latitudinal degrees). These fox time series mirror the dynamics of their dominant small rodent prey, in particular, with respect to cycle period length and spatial synchrony. 3While we found some evidence consistent with previous analyses showing a clearly patterned dynamics according to latitude, such patterns were not stationary on a longer time-scale. In particular, we observed a shift from an extensively synchronous (i.e. regionalized) 4-year cycle north of 60°N just after the ,Little Ice Age' (1880,1910) to a diversification of cycle period length (3,5 years) and eventually, partial loss of cyclicity and synchronicity in later periods. Incidents of loss of cyclicity appeared to be preceded by changes in cycle period (i.e. period lengthening and shortening). 4These results show that the dynamics of Fennoscandian small rodents, and their associated guild of predators, are more prone to change than previously acknowledged. [source] Generic representation and evaluation of properties as a function of position in reciprocal spaceJOURNAL OF APPLIED CRYSTALLOGRAPHY, Issue 6 2002Kevin Cowtan A generalized approach is described for evaluating arbitrary functions of position in reciprocal space. This is a generalization which subsumes a whole range of calculations that form a part of almost every crystallographic software application. Examples include scaling of structure factors, the calculation of structure-factor statistics, and some simple likelihood calculations for a single parameter. The generalized approach has a number of advantages: all these calculations may now be performed by a single software routine which need only be debugged and optimized once; the existing approach of dividing reciprocal space into resolution shells with discontinuities at the boundaries is no longer necessary; the implementation provided makes employing the new functionality extremely simple and concise. The calculation is split into three standard components, for which a number of implementations are provided for different tasks. A `basis function' describes some function of position in reciprocal space, the shape of which is determined by a small number of parameters. A `target function' describes the property for which a functional representation is required, for example . An `evaluator' takes a basis and target function and optimizes the parameters of the basis function to fit the target function. Ideally the components should be usable in any combination. [source] Properties of solid solutions of poly(ethylene oxide)/epoxidized natural rubber blends and LiClO4JOURNAL OF APPLIED POLYMER SCIENCE, Issue 1 2008C. H. Chan Abstract Solid solutions of blends of poly(ethylene oxide) (PEO) and epoxidized natural rubber (ENR) comprising 12 wt % of LiClO4 were studied. Two glass transition temperatures, corresponding to the Tgs of the constituents, confirm immiscibility of the polymers over the entire composition range. It turns out that the Tgs of both polymers slightly increase after addition of salt to the blends. This shift is approximately constant over the whole range of blend composition. Accordingly, Tg measurements reveal that the salt dissolves to approximately equal relative amounts in the two phases. The degree of crystallinity of PEO in blends with ENR descends only to a minor extent with ENR content. However, addition of salt leads first to decreasing crystallinity and second this decrease becomes more pronounced with the addition of ENR. It shows that under these experimental conditions the salt content in PEO increases as compared to ENR. As one expects, the rate of isothermal crystallization does not change in blends as long as PEO is in excess. The situation changes again when salt is added. The rate decreases in a certain range of crystallization temperatures when ENR is added, demonstrating that salt is favorably dissolved in PEO. Conductivity was measured in polymers comprising different salt concentrations. A power-law dependence of conductivity on salt concentration was found. It results that the mobility of charge carriers in PEO exceeds that of ENR by five orders of magnitude. Therefore, the conductivity in blends is primarily governed by PEO as long as PEO is in excess. Conductivity measurements reveal again that salt is preferably dissolved in PEO. The distribution coefficient is estimated. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 [source] Synthesis and simple method of estimating macroporosity of methyl methacrylate,divinylbenzene copolymer beadsJOURNAL OF APPLIED POLYMER SCIENCE, Issue 6 2008Muhammad Arif Malik Abstract Macroporous methyl methacrylate,divinylbenzene copolymer beads having diameter , 300 ,m were synthesized by free radical suspension copolymerization. The macroporosity was generated by diluting the monomers with inert organic liquid diluents. The macroporosity was varied in the range of ,0.1 to , 1.0 mL/g by varying a number of porosity controlling factors, such as the diluents, solvent to nonsolvent mixing ratios when employing a mixture of the two diluents, degree of dilution, and crosslinkage. Increase in pore volume from 0.1 to 0.45 mL/g resulted in a sharp increase in mesopores having diameters in the range of 3,20 nm whereas the macropores remained negligible when compared with mesopores. Increase in pore volume from 0.45 to 1 mL/g resulted in a sharp increase in macropores, whereas mesopores having diameters in the range of 3,20 nm remained almost constant. The mesopores having diameters in the range of 20,50 nm showed an increase with the increase in pore volume throughout the whole range of pore volume studied. Macroporosity characteristics, i.e., pore volume (Vm), surface area (SA), and pore size distributions were evaluated by mercury penetration method. Statistical analysis of the data obtained in the present study shows that the macroporosity characteristics can be estimated with a reasonable accuracy from the pore volumes, which in turn are determined from the densities of the copolymers. These results are explained on the basis of pore formation mechanism. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 [source] | |||||||||||||||||||||||||||||||||||||||||||||||||