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VO2 Max (vo2 + max)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

A Study to Evaluate the Feasibility of an Aerobic Exercise Program in Patients With Migraine

HEADACHE, Issue 4 2009
Emma Varkey RPT
Objectives., The aim of this study was to develop and evaluate an exercise program to improve maximum oxygen uptake (VO2 max) in untrained patients with migraine without making their migraines worse. Patients and methods., Twenty-six patients were studied at a headache clinic in Sweden. The exercise program, based on indoor cycling, was performed 3 times per week during 12 weeks. VO2 max, migraine status, side effects, and quality of life were evaluated. Results., VO2 max increased from 32.9 mL/kg/minute to 36.2 mL/kg/minute (P = .044). Quality of life increased and significant improvements in migraine status (attack frequency, symptom intensity, and intake of medicine) were seen. During the 12 weeks of exercise, on one occasion one patient had a migraine attack, which started immediately after training. No other side effects were reported. Conclusions., The evaluated exercise program was well tolerated by the patients and improved their VO2 max with no deterioration of migraine status. [source]

Oxygen cost of ventilation during incremental exercise to VO2 max

RESPIROLOGY, Issue 2 2006
Chantal A. VELLA
Objective: Evidence of significant oxygen requirements for ventilation during exercise (exercise hyperpnoea) prompted the investigation into whether the oxygen cost of ventilation affects the presence of a whole-body VO2 plateau at maximal exercise. The purposes of this study were to: (i) use isocapnic hyperpnoea trials to determine the oxygen cost of ventilation (VO2VENT) across a range of ventilation (VE); (ii) determine the mean VO2VENT at maximal exercise expressed as a percentage of whole-body VO2 max; and (iii) determine if a plateau in VO2 is more evident when the VO2VENT is subtracted from whole-body VO2 at maximal exercise. Methods: A total of 21 subjects performed a VO2 max test on the cycle ergometer to determine the range of VE for each subject. From the initial VO2 max test, nine VE values across the range of VE were selected for each subject and the oxygen cost of each was measured. Results: The mean maximal VO2VENT equalled 8.8 ± 3.3% of VO2 max and ranged from 5.0% to 17.6%. VO2VENT increased exponentially with increasing VE, but there was considerable subject variability in the oxygen cost per litre of VE as VE increased. Subtracting the VO2VENT from whole-body VO2 at maximal exercise increased the detection of a plateau in VO2 at VO2 max. Conclusions: The data of the present study indicate that the VO2VENT is a significant portion of VO2 max and may be a limiting factor of maximal exercise performance in some subjects. [source]

Airway limitation and exercise intolerance in well-regulated myasthenia gravis patients

ACTA NEUROLOGICA SCANDINAVICA, Issue 2010
A. Elsais
Elsais A, Johansen B, Kerty E. Airway limitation and exercise intolerance in well-regulated myasthenia gravis patients. Acta Neurol Scand: 2010: 122 (Suppl. 190): 12,17. © 2010 John Wiley & Sons A/S. Objectives,,, Myasthenia gravis (MG) is an autoimmune disease of neuromuscular synapses, characterized by muscular weakness and reduced endurance. Remission can be obtained in many patients. However, some of these patients complain of fatigue. The aim of this study was to assess exercise capacity and lung function in well-regulated MG patients. Patients and methods,,, Ten otherwise healthy MG patients and 10 matched controls underwent dynamic spirometry, and a ramped symptom-limited bicycle exercise test. Spirometric variables included forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), and maximum voluntary ventilation (MVV). Exercise variables included maximal oxygen uptake (VO2 max), anaerobic threshold (VO2 AT) maximum work load (W), maximum ventilation (VE max), and limiting symptom. Results,,, Myasthenia gravis patients had significantly lower FEV1/FVC ratio than controls. This was more marked in patients on acetylcholine esterase inhibitors. On the contrary, patients not using acetylcholine esterase inhibitors had a significantly lower exercise endurance time. Conclusion,,, Well-regulated MG patients, especially those using pyridostigmine, tend to have an airway obstruction. The modest airway limitation might be a contributing factor to their fatigue. Patients who are not using acetylcholinesterase inhibitor seem to have diminished exercise endurance in spite of their clinically complete remission. [source]