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Visualization Studies (visualization + studies)
Kinds of Visualization Studies Selected AbstractsFlow Visualization Studies of Exhaust Smoke-Superstructure Interaction on Naval ShipsNAVAL ENGINEERS JOURNAL, Issue 1 2005P.R. Kulkarni The problem of ship funnel exhaust is often studied through flow visualisation using smoke in a wind tunnel. It is a very useful tool for the naval architect to ensure that the funnel exhaust will not interfere during operation. Naval ships are particularly prone to the problem of smoke nuisance because they tend to favor short funnel heights because of competition for topside space. This paper presents the flow visualization studies undertaken to understand the interaction between a bluff body air wake (of the funnel and superstructure/mast) and the ship's exhaust on naval ships. As a first step, the analysis of the exhaust smoke-superstructure interaction was carried out in a wind tunnel for a generic frigate shape. Four variants of the superstructure configuration with progressive introduction of the structures on the topside (i.e. the superstructure/mast upstream and downstream of the funnel) were investigated in the wind tunnel at two velocity ratios through flow visualization studies to understand their effect on the exhaust plume path. Apart from providing an insight into the process of plume dispersion in the vicinity of the funnel and other structures on topside of naval ships, the results of the flow visualization studies presented can also be used for validation of the computational fluid dynamics (CFD) simulations (including particle tracing) of the exhaust smoke-superstructure interaction for cruise vessels, ferries, yachts, as well as naval ships. [source] Laser Doppler Velocimetry and Flow Visualization Studies in the Regurgitant Leakage Flow Region of Three Mechanical Mitral ValvesARTIFICIAL ORGANS, Issue 4 2001Richard S. Meyer Abstract: Streak line flow visualization and laser Doppler velocimetry (LDV) were conducted in the regurgitant leakage flow region of 3 mechanical heart valve types: CarboMedics, Medtronic Hall, and St. Jude Medical. Streak line flow visualization identified regions of high regurgitant flow, and LDV measurements were focused on those locations. Maximum regurgitant flow velocities after valve closure ranged from 0.7 to 2.6 m/s, and maximum Reynolds shear stress after valve closure ranged from 450 to 3,600 dyne/cm2. These data indicate that leakage flows can generate turbulent jets with elevated Reynolds stresses even in bileaflet valves. [source] Two similar enhanced root-colonizing Pseudomonas strains differ largely in their colonization strategies of avocado roots and Rosellinia necatrix hyphaeENVIRONMENTAL MICROBIOLOGY, Issue 12 2008Clara Pliego Summary Pseudomonas alcaligenes AVO73 and Pseudomonas pseudoalcaligenes AVO110 were selected previously as efficient avocado root tip colonizers, displaying in vitro antagonism towards Rosellinia necatrix, causal agent of avocado white root rot. Despite the higher number of antagonistic properties shown in vitro by AVO73, only AVO110 demonstrated significant protection against avocado white root rot. As both strains are enhanced root colonizers, and as colonization is crucial for the most likely biocontrol mechanisms used by these strains, namely production of non-antibiotic antifungal compounds and competition for nutrients and niches, we decided to compare the interactions of the bacterial strains with avocado roots as well as with R. necatrix hyphae. The results indicate that strain AVO110 is superior in biocontrol trait swimming motility and establishes on the root tip of avocado plants faster than AVO73. Visualization studies, using Gfp-labelled derivatives of these strains, showed that AVO110, in contrast to AVO73, colonizes intercellular crevices between neighbouring plant root epidermal cells, a microhabitat of enhanced exudation. Moreover, AVO110, but not AVO73, also colonizes root wounds, described to be preferential penetration sites for R. necatrix infection. This result strongly suggests that AVO110 meets, and can attack, the pathogen on the root. Finally, when co-inoculated with the pathogen, AVO110 utilizes hyphal exudates more efficiently for proliferation than AVO73 does, and colonizes the hyphae more abundantly than AVO73. We conclude that the differences between the strains in colonization levels and strategies are likely to contribute to, and even can explain, the difference in disease-controlling abilities between the strains. This is the first report that shows that two similar bacterial strains, selected by their ability to colonize avocado root, use strongly different root colonization strategies and suggests that in addition to the total bacterial root colonization level, the sites occupied on the root are important for biocontrol. [source] An investigation of pulsatile flow in a model cavo-pulmonary vascular systemINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Issue 11 2009K. Chitra Abstract The complexities in the flow pattern in a cavo-pulmonary vascular system,after application of the Fontan procedure in the vicinity of the superior vena cava, inferior vena cava, and the confluence at the T-junction,are analysed. A characteristic-based split (CBS) finite element scheme involving the artificial compressibility approach is employed to compute the resulting flow. Benchmarking of the CBS scheme is carried out using standard problems and with the flow features observed in an experimental model with the help of a dye visualization technique in model scale. The transient flow variations in a total cavo-pulmonary connection (TCPC) under pulsatile conditions are investigated and compared with flow visualization studies. In addition to such qualitative flow investigations, quantitative analysis of energy loss and haemodynamic stresses have also been performed. The comparisons show good agreement between the numerical and experimental flow patterns. The numerically predicted shear stress values indicate that the pulsatile flow condition is likely to be more severe than steady flow, with regard to the long-term health of the surgically corrected TCPC. Copyright © 2008 John Wiley & Sons, Ltd. [source] Heterogeneity in skin treated with low-frequency ultrasoundJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 10 2008Joseph Kushner IV Abstract Recent experimental evidence using colored, fluorescent permeants suggests that skin treated with low-frequency sonophoresis (LFS) is perturbed in a heterogeneous manner. Macroscopic and microscopic visualization studies, topical penetration studies, transdermal permeability studies, and skin electrical resistivity measurements have shown that discrete domains, referred to as localized transport regions (LTRs), which are formed during LFS treatment of the skin, possess greatly reduced barrier properties, and therefore exhibit increased permeant skin penetration, compared to the surrounding regions of LFS-treated skin. The transformation of LTR formation from a heterogeneous to a homogeneous phenomenon has the potential benefit of increasing the maximum level of transdermal permeability or of reducing the area of skin required to deliver a desired dose of drug transdermally. Future studies, aimed at elucidating both the mechanisms of LTR formation and the limits of nondamaging formation of LTRs in the skin, are required to incorporate these proposed improvements to enhance the efficacy and practical utility of low-frequency sonophoresis. © 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97:4119,4128, 2008 [source] Flow Visualization Studies of Exhaust Smoke-Superstructure Interaction on Naval ShipsNAVAL ENGINEERS JOURNAL, Issue 1 2005P.R. Kulkarni The problem of ship funnel exhaust is often studied through flow visualisation using smoke in a wind tunnel. It is a very useful tool for the naval architect to ensure that the funnel exhaust will not interfere during operation. Naval ships are particularly prone to the problem of smoke nuisance because they tend to favor short funnel heights because of competition for topside space. This paper presents the flow visualization studies undertaken to understand the interaction between a bluff body air wake (of the funnel and superstructure/mast) and the ship's exhaust on naval ships. As a first step, the analysis of the exhaust smoke-superstructure interaction was carried out in a wind tunnel for a generic frigate shape. Four variants of the superstructure configuration with progressive introduction of the structures on the topside (i.e. the superstructure/mast upstream and downstream of the funnel) were investigated in the wind tunnel at two velocity ratios through flow visualization studies to understand their effect on the exhaust plume path. Apart from providing an insight into the process of plume dispersion in the vicinity of the funnel and other structures on topside of naval ships, the results of the flow visualization studies presented can also be used for validation of the computational fluid dynamics (CFD) simulations (including particle tracing) of the exhaust smoke-superstructure interaction for cruise vessels, ferries, yachts, as well as naval ships. [source] The Importance of dQ/dt on the Flow Field in a Turbodynamic Pump With Pulsatile FlowARTIFICIAL ORGANS, Issue 9 2009Fangjun Shu Abstract Fluid dynamic analysis of turbodynamic blood pumps (TBPs) is often conducted under steady flow conditions. However, the preponderance of clinical applications for ventricular assistance involves unsteady, pulsatile flow,due to the residual contractility of the native heart. This study was undertaken to demonstrate the importance of pulsatility and the associated time derivative of the flow rate (dQ/dt) on hemodynamics within a clinical-scale TBP. This was accomplished by performing flow visualization studies on a transparent model of a centrifugal TBP interposed within a cardiovascular simulator with controllable heart rate and stroke volume. Particle image velocimetry triggered to both the rotation angle of the impeller and phase of the cardiac cycle was used to quantify the velocity field in the outlet volute and in between the impeller blades for 16 phases of the cardiac cycle. Comparison of the unsteady flow fields to corresponding steady conditions at the same (instantaneous) flow rates revealed marked differences. In particular, deceleration of flow was found to promote separation within the outlet diffuser, while acceleration served to stabilize the velocity field. The notable differences between the acceleration and deceleration phases illustrated the prominence of inertial fluid forces. These studies emphasize the importance of dQ/dt as an independent variable for thorough preclinical validation of TBPs intended for use as a ventricular assist device. [source] Multimodal Flow Visualization and Optimization of Pneumatic Blood Pump for Sorbent Hemodialysis SystemARTIFICIAL ORGANS, Issue 4 2009Fangjun Shu Abstract:, Renal Solutions Allient Sorbent Hemodialysis System utilizes a two-chambered pneumatic pump (Pulsar Blood Pump, Renal Solutions, Inc., Warrendale, PA, USA) to avoid limitations associated with peristaltic pumping systems. Single-needle access is enabled by counter-pulsing the two pump chambers, thereby obviating compliance chambers or blood reservoirs. Each chamber propels 20 cc per pulse of 3 s (dual access) or 6 s (single access) duration, corresponding to a peak Reynolds number of approximately 8000 (based on inlet velocity and chamber diameter). A multimodal series of flow visualization studies (tracer particle, dye washout, and dye erosion) was conducted on a sequence of pump designs with varying port locations and diaphragms to improve the geometry with respect to risk of thrombogenesis. Experiments were conducted in a simplified flow loop using occluders to simulate flow resistance induced by tubing and dialyzer. Tracer visualization revealed flow patterns and qualitatively indicated turbulence intensity. Dye washout identified dwell volume and areas of flow stagnation for each design. Dye erosion results indicated the effectiveness and homogeneity of surface washing. Compared to a centered inlet which resulted in a fluid jet that produced two counter-rotating vortices, a tangential inlet introduced a single vortex, and kept the flow laminar. It also provided better surface washing on the pump inner surface. However, a tangential outlet did not present as much benefit as expected. On the contrary, it created a sharp defection to the flow when transiting from filling to ejection. [source] Concept for a New Hydrodynamic Blood Bearing for Miniature Blood Pumps,ARTIFICIAL ORGANS, Issue 10 2004Thomas Kink Abstract: The most crucial element of a long-term implantable rotary blood pump is the rotor bearing. Because of heat generation and power loss resulting from friction, seals within the devices have to be avoided. Actively controlled magnetic bearings, although maintenance-free, increase the degree of complexity. Hydrodynamic bearings for magnetically coupled rotors may offer an alternative solution to this problem. Additionally, for miniature pumps, the load capacity of hydrodynamic bearings scales slower than that of, for example, magnetic bearings because of the cube-square-law. A special kind of hydrodynamic bearing is a spiral groove bearing (SGB), which features an excellent load capacity. Mock-loop tests showed that SGBs do not influence the hydraulic performance of the tested pumps. Although, as of now, the power consumption of the SBG is higher than for a mechanical pivot bearing, it is absolutely contact-free and has an unlimited lifetime. The liftoff of the rotor occurs already at 10% of design speed. Further tests and flow visualization studies on scaled-up models must demonstrate its overall blood compatibility. [source] Improvement on the Auxiliary Total Artificial Heart (ATAH) Left Chamber Design,ARTIFICIAL ORGANS, Issue 5 2003Aron Andrade Abstract: The auxiliary total artificial heart (ATAH) is an electromechanically driven artificial heart with reduced dimensions, which is able to be implanted in the right thoracic or abdominal cavities of an average human patient without removing the natural heart or the heart neurohumoral inherent control mechanism for the arterial pressure. This device uses a brushless direct current motor and a mechanical actuator (roller screw) to move two diaphragms. The ATAH's beating frequency is regulated through the change of the left preload, based on Frank-Starling's law, assisting the native heart in obtaining adequate blood flow. The ATAH left and right stroke volumes are 38 ml and 34 ml, respectively, giving approximately 5 L/min of cardiac output at 160 bpm. Flow visualization studies were performed in critical areas on the ATAH left chamber. A closed circuit loop was used with water and glycerin (37%) at 25°C. Amberlite particles (80 mesh) were illuminated by a 1 mm planar helium-neon laser light. With left mean preload fixed at 10 mm Hg and the afterload at 100 mm Hg, the heart rate varied from 60 to 200 bpm. Two porcine valves were used on the inlet and outlet ports. The flow pattern images were obtained using a color micro-camera and a video recorder. Subsequently, these images were digitized using a PC computer. A persistent stagnant flow was detected in the left chamber inlet port. After improvement on the left chamber design, this stagnant flow disappeared. [source] | ||||||||||