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Vitamin E Supplements (vitamin + e_supplement)

Distribution by Scientific Domains

Medical Sciences	75%

Selected Abstracts

Influence of glutamine and vitamin E on growth and antioxidant capacity of fish enterocytes

AQUACULTURE NUTRITION, Issue 4 2009
J. JIANG
Abstract The present study explored the effect of glutamine and vitamin E on growth and anti-oxidation capacity of isolated fish enterocytes. Fish enterocytes were cultured with six medium, respectively, containing 0, 2.0, 4.7, 6.8, 8.1, 9.2 mmol L,1 glutamine for 64 h. The results showed that glutamine could promote fish enterocytes proliferation and differentiation. Fish enterocytes were cultured with different medium containing 0, 2.5, 3.5, 4.5, 6.0, 7.0 ,g mL,1 vitamin E for 96 h. The results showed that cells proliferation and differentiation were not significantly enhanced, but anti-superoxide anion activity, anti-hydroxy radical activity, reduced glutathione concentration, the ratio between reduced and total glutathione in the cells were significantly enhanced, and the malondialdehyde concentration in the culture medium was significantly depressed with the vitamin E treatment. In the whole, the present results firstly indicated that glutamine could promote fish enterocytes growth, but vitamin E could not. Vitamin E could promote fish enterocytes antioxidant capacity and cellular structural integrity. These data would be instructive for glutamine and vitamin E supplement in aquaculture diets. [source]

Selenium and vitamin E supplements do not prevent prostate cancer: the importance of prospective RCTs for definitive practice guidelines

FOCUS ON ALTERNATIVE AND COMPLEMENTARY THERAPIES AN EVIDENCE-BASED APPROACH, Issue 3 2009
Article first published online: 3 JUN 2010
[source]

Vitamin E and K interactions , a 50-year-old problem

NUTRITION REVIEWS, Issue 11 2008
Maret G Traber
The mechanisms by which vitamin E interferes with vitamin K activity, especially blood clotting, are not known, but hypothetically this interference may involve metabolic pathways. Phylloquinone (K1) must be converted to menaquinone (MK-4, the most potent extrahepatic tissue vitamin K) by truncation of the K1 side chain and replacement with geranylgeranyl. Possible mechanisms for the vitamin E and K interaction include: 1) vitamin E competes for the yet undiscovered enzyme that truncates the K1 side chain; 2) vitamin E competes with K1 for the hypothetical cytochrome P450 enzyme that ,-hydroxylates the K1 side chain, thereby preventing its ,-oxidation and its removal for MK-4 formation; or 3) vitamin E increases xenobiotic pathways that increase hepatic metabolism and excretion of all vitamin K forms. Currently, the pathway for K1 conversion to MK-4 is unknown, the process for regulating vitamin K metabolism to urinary excretion products is unknown, and why vitamin E supplements have such a dramatic effect, causing bleeding in some individuals and not in others, remains a mystery. [source]

Intake of vitamin C and E in pregnancy and risk of pre-eclampsia: prospective study among 57 346 women

BJOG : AN INTERNATIONAL JOURNAL OF OBSTETRICS & GYNAECOLOGY, Issue 7 2009
ÅK Klemmensen
Objective, It has been suggested that vitamin C, alone or in combination with vitamin E, may protect against pre-eclampsia, whereas the safety of high-dose vitamin E supplements has been questioned. We investigated dietary intakes of vitamins C and E to see if they correlated with the incidence of pre-eclampsia. Design, Prospective cohort study. Setting, The Danish National Birth Cohort; a population-based pregnancy cohort; analyses were based on 57 346 pregnancies. Methods, Vitamin intake was estimated from a food frequency questionnaire completed in gestational week 25, recording intake from diet and supplements during the previous four weeks. Pre-eclampsia diagnoses were obtained from the Danish National Patient Registry; we worked with two entities, ,pre-eclampsia (all types)' and ,severe pre-eclampsia/eclampsia/HELLP'. We adjusted for confounding factors by logistic regression. Main outcome measures, A small increase in the incidence of severe disease was also seen in the group of women (64, n = 49 373) with a high intake of vitamin E from supplements and dietary sources. Results, The incidence of ,pre-eclampsia (all types)' did not correlate with dietary vitamin C and E intake. There was a decreasing trend (P = 0.01) in the incidence of ,severe pre-eclampsia/eclampsia/HELLP' with increasing dietary vitamin C intake; with an intake of 130,170 mg/day as reference, odds ratios ranged from 1.21 (95% confidence interval 0.83 to 1.75) for an intake below 70 mg/day to 0.70 (0.40 to 1.23) for an intake exceeding 275 mg/day (total n = 57 346). For vitamin E intake aggregated from diet and supplements (n = 49 373), with an intake of 10.5,13.5 mg/day as reference, the ,severe pre-eclampsia/eclampsia/HELLP' odds ratio was 1.46 (1.02 to 2.09) for an intake exceeding 18 mg/day. Conclusions, Low dietary intake of vitamin C was associated with a trend towards an increased incidence of either severe pre-eclampsia, eclampsia or HELLP. A small increase in the incidence of severe disease was also seen in the group of women with a high intake of vitamin E from supplements and dietary sources. [source]