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Selected AbstractsFlexMaster: a universal systemENDODONTIC TOPICS, Issue 1 2005David Sonntag FlexMaster® NiTi files have been in successful application for some years, not only in Germany but also worldwide, and their use is becoming increasingly widespread. The cutting blade design of K-type files provides for efficient working and effective removal of dentinal debris. Due to their convex cross-sectional profile, these instruments are moreover equipped with a more solid instrument core which reduces the risk of fractures and deformations. FlexMaster® instruments are among the most comprehensively investigated rotary NiTi instruments. Very good results have been reported both in numerous in vitro studies and in an in vivo setting. The present article elucidates and assesses both the scientific setting and the clinical aspects of the system. [source] ROLE OF SATURATED FATTY ACIDS IN LIPASE PRODUCTION , USING PSEUDOMONAS AERUGINOSAJOURNAL OF FOOD BIOCHEMISTRY, Issue 6 2007A.N. SARAVANAN ABSTRACT Complex substrates always induce substantial amount of enzyme production during hydrolysis by microorganisms. In this study, ghee was taken for its saturated fatty acid content and analyzed as an inducer for the production of lipase. With ghee emulsion, the bacterium Pseudomonas aeruginosa at optimal condition produced 60 units/min/L at 72 h. With olive oil emulsion, this organism produced only 41 units/min/L as maximum at 96 h. The saturated fatty acids present in ghee make it a hard substance for hydrolysis, which is the reason for the increased enzyme production. This was evaluated by the iodine number experiment. Ghee can also reduce the production cost whereas the costlier olive oil constitutes 25,50% of the total production cost for a commercial scale. The experimental results showed that the saturated fatty acids play an important role in lipase enzyme induction by P. aeruginosa. The use of ghee is cost-effective; hence, it can be used as a potential inducer for lipase production. PRACTICAL APPLICATIONS Lipases are industrially very important enzymes. They are used in pharmaceutical, food, soap and other industries. In lipase production, olive oil is the main constituent. Comparatively, olive oil is costlier; hence, it increases the production cost of lipase. So, this study was done to replace olive oil with a much cheaper ghee using Pseudomonas aeruginosa. The ghee-containing medium gave a very good result because of the presence of complex saturated fatty acids. The ghee-containing medium produced 60 units/min/L at 72 h. The olive oil medium, which contains mainly unsaturated fatty acids, produced only 41 units/min/L as maximum at 96 h. Hence, in the commercial scale, ghee can reduce raw material cost as well as operation time cost significantly when it is used as substrate. [source] Diagnostic criteria and surgical procedure for megaesophagus , a personal experienceDISEASES OF THE ESOPHAGUS, Issue 4 2009A. Lewandowski SUMMARY Megaesophagus is the end-stage of achalasia cardiae. It is the result of peristaltic disorders and slow decompensation of the muscular layer of the esophagus. The aim of this article is to detail the diagnostic criteria and surgical management of megaesophagus. Criteria were acute bending of esophagus axis; lack of esophagus peristalsis, and no response to stimulation in the manometric test; and Los Angeles C/D esophagitis in the endoscopic examination. Between 1991 and 2004 seven patients (5 females, 2 males; age, 51,67 years; average age, 59 ± 8 years) were treated. A bypass made from the pedunculated part of the jejunum connecting the part of esophagus above the narrowing with the praepyloric part of the stomach was made. Access was by an abdominal approach. A jejunum bypass was made in six patients with megaesophagus. A transhiatal esophageal resection was carried out, and in the second stage a supplementary esophagus was made from the right half of the colon on the ileocolic vessels in one patient who had experienced two earlier unsuccessful operations. Symptoms of dysphagia, recurrent inflammation of the respiratory tract, and pain subsided in all patients. Complications were not reported in the postoperative period. All patients survived. Subsequent radiographic and endoscopic examination showed very good outcome. The jejunum bypass gave very good results in the surgical treatment of megaesophagus. [source] A gradient smoothing method (GSM) for fluid dynamics problemsINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 10 2008G. R. Liu Abstract A novel gradient smoothing method (GSM) based on irregular cells and strong form of governing equations is presented for fluid dynamics problems with arbitrary geometries. Upon the analyses about the compactness and the positivity of coefficients of influence of their stencils for approximating a derivative, four favorable schemes (II, VI, VII and VIII) with second-order accuracy are selected among the total eight proposed discretization schemes. These four schemes are successively verified and carefully examined in solving Poisson's equations, subjected to changes in the number of nodes, the shapes of cells and the irregularity of triangular cells, respectively. Numerical results imply us that all the four schemes give very good results: Schemes VI and VIII produce a slightly better accuracy than the other two schemes on irregular cells, but at a higher cost in computation. Schemes VII and VIII that consistently rely on gradient smoothing operations are more accurate than Schemes II and VI in which directional correction is imposed. It is interestingly found that GSM is insensitive to the irregularity of meshes, indicating the robustness of the presented GSM. Among the four schemes of GSM, Scheme VII outperforms the other three schemes, for its outstanding overall performance in terms of numerical accuracy, stability and efficiency. Finally, GSM solutions with Scheme VII to some benchmarked compressible flows including inviscid flow over NACA0012 airfoil, laminar flow over flat plate and turbulent flow over an RAE2822 airfoil are presented, respectively. Copyright © 2008 John Wiley & Sons, Ltd. [source] Recent Activities of HTS Power Application in KoreaINTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY, Issue 3 2007Minwon Park From April 2007, DAPAS (Development of the Advanced Power system by Applied Superconductivity technologies), which is a 10-year-long program, entered the final phase with 4 years. For the last 7 years, the significant achievement of DAPAS is that a 10 m long and 100 A critical current-coated conductor and core technologies of distribution line voltage class HTS power systems including cables, transformers, fault current limiters (FCLs), and motors have been developed. In particular, a 100 m length HTS power cable was installed and is operating well in the Gochang power system test center. Two different types of FCL were successfully developed and demonstrated very good results of fault current test with 22.9 kV distribution line voltage class. In the case of the HTS motor, it was well operated too on connecting to 2 units of a 1.1 MVA conventional induction motor each as a load. In addition, the coated conductor project team achieved a 30 m length and 185 A critical current-coated conductor tape after 6 months since the hardware was set up. [source] Evaluation of the intramolecular basis set superposition error in the calculations of larger molecules: [n]helicenes and Phe-Gly-Phe tripeptideJOURNAL OF COMPUTATIONAL CHEMISTRY, Issue 6 2008Haydée Valdés Abstract Correlated ab initio calculations on large systems, such as the popular MP2 (or RI-MP2) method, suffer from the intramolecular basis set superposition error (BSSE). This error is typically manifested in molecules with folded structures, characterized by intramolecular dispersion interactions. It can dramatically affect the energy differences between various conformers as well as intramolecular stabilities, and it can even impair the accuracy of the predictions of the equilibrium molecular structures. In this study, we will present two extreme cases of intramolecular BSSE, the internal stability of [n]helicene molecules and the relative energies of various conformers of phenylalanyl-glycyl-phenylalanine tripeptide (Phe-Gly-Phe), and compare the calculated data with benchmark values (experimental or high-level theoretical data). As a practical and cheap solution to the accurate treatment of the systems with large anticipated value of intramolecular BSSE, the recently developed density functional method augmented with an empirical dispersion term (DFT-D) is proposed and shown to provide very good results in both of the above described representative cases. © 2007 Wiley Periodicals, Inc. J Comput Chem 2008 [source] Gaussian Process Functional Regression Modeling for Batch DataBIOMETRICS, Issue 3 2007J. Q. Shi Summary A Gaussian process functional regression model is proposed for the analysis of batch data. Covariance structure and mean structure are considered simultaneously, with the covariance structure modeled by a Gaussian process regression model and the mean structure modeled by a functional regression model. The model allows the inclusion of covariates in both the covariance structure and the mean structure. It models the nonlinear relationship between a functional output variable and a set of functional and nonfunctional covariates. Several applications and simulation studies are reported and show that the method provides very good results for curve fitting and prediction. [source] Uretero-ureterocutaneostomy (wrapped by omentum)BJU INTERNATIONAL, Issue 3 2005Michele Lodde The tubularized-incised plate urethroplasty has traditionally been used in children for repairing hypospadias. As shown here, it can also be used successfully in adults, with very good results. The rate of wound healing, infection and complications is the same as in children, as are the cosmetic and functional outcomes. OBJECTIVES To evaluate the outcome of uretero-ureterocutaneostomy (UUC) wrapped by omentum for palliative cystectomy in symptomatic elderly high-risk patients with high-stage bladder cancer. PATIENTS AND METHODS The study included 15 patients (14 men and one woman, aged 72,87 years, American Society of Anesthesiology score 3) with symptomatic recurrent bleeding bladder cancer (T2/T3) who were treated with palliative cystectomy. UUC was performed by mobilizing the right pre-vesical divided ureter up to the pelvi-ureteric junction and a high retroperitoneal crossover to the divided left ureter. A stoma was created with a circular 2-cm skin excision and resecting the fatty subcutaneous tissue. Wrapped by the omentum, both well-vascularized ureteric stumps were pulled through a cross-like fascia incision up to skin level. Spatulated and everted, the ,butterfly' flaps were fixed to the skin and underlying omentum. Soft splints were inserted for 21 days and a Karaya ring placed. RESULTS The postoperative course and stoma healing was normal in 14 of the 15 patients; the sigmoid was resected because of sigmoid diverticulitis in one. The median (range) follow-up was 15 (6,24) months. There was pyelonephritis in one patient, and the dilatation of the upper tract (grade 3) in two returned to grade 2, with new asymptomatic grade 1 dilatation in one other. All patients were without stents and stoma care was provided at home. CONCLUSIONS This modified UUC by omental wrapping in 15 high-risk patients after palliative cystectomy was simple and safe, and their recovery was uneventful. To date the few patients with stomal obstruction were managed by J catheters, changed every 4,6 months. [source] Single-tooth replacement by immediate implant and connective tissue graft: a 1,9-year clinical evaluationCLINICAL ORAL IMPLANTS RESEARCH, Issue 3 2004Andrea E. Bianchi Abstract Objectives: The aim of the present study was to evaluate the long-lasting efficacy of a combined surgical protocol, using immediate implant and subepithelial connective tissue graft for single-tooth replacement. The advantages of this single-center, longitudinal, randomized, blind examiner research were the following: preservation of both keratinized mucosa amount and bone tissue, optimal peri-implant marginal sealing, satisfactory aesthetic results, reduction in treatment time. Materials and methods: In the time period from 1990 to 1998, 116 patients were consecutively admitted for treatment with a total of 116 solid screw ITI-implants supporting single crowns. Ninety-six patients underwent the proposed combined treatment (test group), while 20 received only single immediate implants (control group). The observation time extended from 1 up to 9 years. Results: The 9-year cumulative survival rate was 100% for both test and control groups. Comparative statistical analysis of soft and hard tissue peri-implant parameters demonstrated better results in the test group than in the control during every single 3-year analysis and especially in the last observation interval. The test group also showed very good results in terms of aesthetic parameters, which estimated the keratinized mucosa width, the alignment of crown emergence profile and the patient's satisfaction. Conclusion: Single-tooth replacement by immediate solid screw ITI implants in association with connective tissue autograft was demonstrated to be a predictable procedure. Moreover, this treatment can be considered as a sure system to reach an excellent functional and harmonious aesthetic restoration. Résumé Le but de l'étude présente a été d'évaluer l'efficacitéà long terme d'un protocole chirurgical combiné utilisant l'implant placé immédiatement et un greffon tissulaire de tissu conjonctif sous-épithélial pour le remplacement d'une dent unique. Les avantages de cette recherche randomisée longitudinale dans un seul centre et en aveugle étaient les suivants : préservation de la quantité de muqueuse kératinisée et du tissu osseux, une fermeture marginale paroïmplantaire optimale, des résultats esthétiques satisfaisants et une réduction du temps de traitement. Durant les années 1990 à 1998, 116 patients ont été admis pour le traitement de 116 implants ITI en vis pleines portant des couronnes uniques. Nonante-six patients ont recu le traitement proposé (groupe test) tandis que 20 autres n'ont reçu que des implants placés immédiatement en une étape (groupe contrôle). Le temps d'observation s'échelonnait de un à neuf ans. Le taux de survie cumulatif à neuf années était de 100% dans les deux groupes. L'analyse statistique comparative des tissus mous et durs paroïmplantaires a constaté des meilleurs résultats dans le groupe test que dans le groupe contrôle durant chaque analyse de trois ans et spécialement dans la dernière période d'observation. Le groupe test montrait également de très bons résultats esthétiques concernant la largeur de la muqueuse kératinisée, l'alignement du profil de l'émergence de la couronne et la satisfaction du patient. Le remplacement de dents uniques par des implants ITI en vis pleines placées immédiatement en association avec une greffe de tissu conjonctif est un processus prévisible. De plus, ce traitement peut être considéré comme un système sûr pouvant apporter une restauration fonctionnelle harmonieuse et esthétique. Zusammenfassung Ziele: Das Ziel dieser Studie war es, den Langzeiterfolg eines chirurgischen Protokolls zu untersuchen, das den Einzelzahnersatz mit einem Sofortimplantat in Kombination mit einem subepithelialen Bindegewebstransplantat vorsah. Die Vorteile dieser an einem Zentrum durchgeführten randomisierten, longitudinalen Blindstudie waren die folgenden: Erhaltung sowohl der gesamten keratinisierten Mukosa wie auch des Knochengewebes, der optimale perimplantäre marginale Abschluss, die befriedigenden ästhetischen Resultate und die Verkürzung der Behandlungszeit. Material und Methoden: In der Zeit von 1990 bis 1998 bekamen in der Folge 116 Patienten insgesamt 116 ITI-Vollschraubenimplantate, die mit Einzelkronen versorgt wurden. 96 Patienten wurden nach der vorgestellten kombinierten Methode behandelt (Testgruppe), währenddem die übrigen 20 Patienten einzig das Sofortimplantat erhielten (Kontrollgruppe). Die Beobachtungszeit reichte von 1 bis zu 9 Jahren. Resultate: Die kumulative Überlebensrate nach 9 Jahren betrug für Test- und Kontrollgruppe 100%. Eine statistische Vergleichsanalyse der Parameter von Weich- und Hartgeweben zeigte während jeder der dreijährigen Beobachtungsphasen (insbesondere in der letzten) in der Testgruppe bessere Resultate als in der Kontrollgruppe. Die Testgruppe zeigte auch bezüglich ästhetischen Parametern (Breite der keratinisierten Gingiva, Lokalisation der Durchtrittsstelle der Krone, Zufriedenheit des Patienten) sehr schöne Resultate. Zusammenfassung: Der Einzelzahnersatz mittels Sofortimplantation einer ITI-Vollschraube in Verbindung mit einem freien Bindegewebetransplantat erwies sich als gut beherrschbare Methode. Man kann diese Behandlung sogar als sicher für den Erhalt einer hervorragenden funktionellen, harmonischen und ästhetischen Rekonstruktion empfehlen. Resumen Objetivos: La intención del presente estudio fue evaluar la eficacia a largo plazo de un protocolo quirúrgico combinado, usando implantes inmediatos e injertos de tejido conectivo subepitelial para reemplazar dientes unitarios. Las ventajas de esta investigación unicentro, longitudinal, aleatoria, examinador ciego fueron las siguientes: preservación de tanto de la cantidad de mucosa queratinizada como del tejido óseo, sellado marginal periimplantario óptimo, resultados estéticos satisfactorios, reducción del tiempo del tratamiento. Material y métodos: En el periodo de tiempo desde 1990 a 1998, se admitieron 116 pacientes consecutivos para tratamiento con un total de 116 implantes macizos roscados ITI soportando coronas unitarias. Noventa y seis pacientes se sometieron al tratamiento propuesto (grupo de prueba), mientras 20 recibieron solo implantes inmediatos unitarios (grupo de control). El tiempo de observación se extendió de 1 9 años. Resultados: El índice acumulado de supervivencia a los 9 años fue del 100% tanto para el grupo de prueba como el de control. El análisis estadístico comparativo de los parámetros de los tejidos blandos y duros periimplantarios demostró mejores resultados en el grupo de prueba que en el de control, durante cada análisis de 3 años y especialmente en el último intervalo de observación. El grupo de prueba también mostró muy buenos resultados en términos de parámetros estéticos, que estimaron la anchura de la mucosa queratinizada, la alineación del perfil de emergencia de la corona y la satisfacción del paciente. Conclusión: La sustitución de un diente unitario por implantes macizos roscados inmediatos ITI en asociación con autoinjertos de tejido conectivo demostró ser un procedimiento predecible. Más aun, este tratamiento puede ser considerado como un sistema seguro para alcanzar una excelente restauración estética funcional y armónica. [source] | |||||||||||||