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Very Dissimilar (very + dissimilar)
Selected AbstractsA systematic review of counselling for HIV testing of pregnant womenJOURNAL OF CLINICAL NURSING, Issue 13 2009Karin S Minnie Background., Evidence-based strategies have made it possible to limit mother-to-child transmission of the HI-virus to a large extent and enable HIV-positive women to stay healthy for longer, provided their HIV status is known. Although voluntary counselling and testing for HIV is part of routine antenatal care in South Africa, the uptake of testing varies and a large number of pregnant women's HIV status is not known at the time of birth. Aim., The aim of the study was to establish research evidence regarding factors influencing counselling for HIV testing during pregnancy by means of systematic review, forming part of a larger study using a variety of evidence to develop best practice guidelines. Design., Systematic review. Methods., The question steering the review was: ,What factors influence counselling for HIV testing during pregnancy?'. A multi-stage search of relevant research studies was undertaken using a variety of sources. A total of 33 studies were retrieved and critically appraised. Data were extracted from the studies and assessed according to its applicability in the South African context. Results., The results are presented according to the following themes: effects of counselling, quality of counselling, group vs. individual counselling, ways of offering HIV testing, rapid testing, counselling and testing during labour, couple counselling and testing, counsellor and organisational factors. Conclusions., According to research evidence, factors such as whether counselling is presented in a group or individually, different ways to present HIV testing as well as counsellor and organisational factors can influence counselling for HIV testing during pregnancy. When developing best practice guidelines for settings very dissimilar from where the research was done, research evidence must be contextualised. Relevance to clinical practice., Implementation of the best practice guidelines may lead to the increased uptake of HIV testing in pregnancy in developing countries like South Africa and thus to an increase in the number of women whose status is known when their babies are born. [source] Image Segmentation and Bruise Identification on Potatoes Using a Kohonen's Self-Organizing MapJOURNAL OF FOOD SCIENCE, Issue 7 2005Thierry Marique ABSTRACT: Potato quality includes a low incidence of colored bruises resulting from bad storage or manipulation practices. We developed a procedure to process and segment potato images by using Kohonen's self-organizing map. Anomalous regions could be distinguished on 3 potato varieties. Bruises that were very dissimilar in appearance were correctly identified, and some particular defects such as green spots could be located as well. [source] Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell linesTHE PROSTATE, Issue 2 2004Alvin Y. Liu Abstract BACKGROUND LNCaP and its derivative cell lines, which include C4-2 (and the related C4-2B) and CL1, are used as models of prostate cancer. Unlike LNCaP, the other cell lines show features of progressed disease such as metastatic capability and hormone independence. Analyses were done to determine if C4-2 or CL1 cells were selected from pre-existent subpopulations in LNCaP. METHODS Prostate cancer cells were characterized by cluster designation (CD) phenotyping. Specific cell populations were sorted by flow cytometry. DNA array analysis was used to probe differential gene expression. RESULTS CD phenotyping showed that CL1 and C4-2 (and C4-2B) were very dissimilar, and C4-2 was more similar to LNCaP. One common difference between LNCaP and its derivatives was CD26, in which virtually all C4-2 or CL1 cells were CD26+ but only ,10% of LNCaP cells were CD26+. The CD26+ subpopulation of LNCaP was isolated and cultured in vitro. After culture, a high percentage of the cells (descended from the sorted cells) were CD26+, in contrast to those sorted by CD13 or CD44. The cultured CD13 and CD44 populations did not show a high percentage of CD13+ and CD44+ cells, respectively. CD13 and CD44 are markers, in addition to CD26, for CL1 but not for C4-2. CONCLUSIONS C4-2 arose probably from CD26+ LNCaP cells, while CL1 arose de novo. © 2004 Wiley-Liss, Inc. [source] Cost of disorders of the brain in NorwayACTA NEUROLOGICA SCANDINAVICA, Issue 2010L. J. Stovner Stovner LJ, Gjerstad L, Gilhus NE, Storstein A, Zwart JA. Cost of disorders of the brain in Norway. Acta Neurol Scand: 2010: 122 (Suppl. 190): 1,5. © 2010 John Wiley & Sons A/S. Background,,, Little is known about the cost of neurological disorders in Norway. Objectives,,, To estimate the cost of disorders of the brain, including the main psychiatric, neurological and neurosurgical conditions in Norway. Methods,,, Most of the data are extrapolations from a large European cost study that collected the best available epidemiological and health economical evidence for the year 2004. Some epidemiological data are available from Norway, but very little on costs. Results,,, Brain disorders seemed to affect 1.5 million Norwegians in 2004, and the total cost amounted to 5.8 billion Euros. The most prevalent disorders are anxiety disorders and migraine, and the most costly are affective disorders, addiction and dementia. Migraine is the most costly of the purely neurological conditions, followed by stroke, epilepsy and Parkinson's disease. The indirect costs account for more than half of the total costs. Discussion,,, Although the different brain disorders are very dissimilar in appearance, from health economic and public health perspectives, it is relevant to view them as a whole, since many of them share important pathophysiological mechanisms. This means that new insights into one disorder can have relevance for many other disorders. Conclusion,,, As a result of the high impact on individuals and society, more resources should be allocated to treatment and research into brain disorders. [source] | ||||||||||