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Terms modified by Utah Selected AbstractsWAL-MART AND BANKS: SHOULD THE TWAIN MEET?CONTEMPORARY ECONOMIC POLICY, Issue 4 2009A PRINCIPLES-BASED APPROACH TO THE ISSUES OF THE SEPARATION OF BANKING AND COMMERCE The application in July 2005 by Wal-Mart to obtain a specialized bank charter from the state of Utah and to obtain federal deposit insurance reopened a national debate concerning the separation of banking and commerce. Though Wal-Mart withdrew its application in March 2007, the issue and the debate continue. This article offers a principles-based approach to this issue that begins with the recognition that banks are special and that safety and soundness regulation of banks is therefore warranted. Building on that recognition, the article lays out the principle that the "examinability and supervisability" of an activity should determine if that activity should be undertaken by a bank. Even if an otherwise legitimate activity is not suitable for a bank, it should be allowed for a bank's owners (whether the owners are individuals or a holding company), so long as the financial transactions between the bank and its owners are closely monitored by bank regulators. The implications of this set of ideas for the Wal-Mart case and for banking and commerce generally are then discussed. (JEL G21, G28) [source] A Comparison of Four Mohs Tissue Preparation Methods Using Porcine SkinDERMATOLOGIC SURGERY, Issue 9 2010FRCPC, WILLIAM LEAR MD OBJECTIVE Mohs surgery relies on high-quality, rapid tissue preparation and processing. This study evaluated four currently performed tissue preparation and processing methods for speed of processing and depth of cut into the tissue block to achieve a complete high-quality section. METHODS The following four methods were tested: cryoEMBEDDER, float, heat sink, and slide. Standardized specimens of porcine skin were used to ensure uniformity. We measured the time required for a technician to flatten, embed, and cut to the first complete section of each specimen. Additionally, we measured the depth in microns required to cut into an embedded specimen to achieve a complete section. RESULTS There were advantages and disadvantages of each method, and our findings suggest that the heat sink and float methods are more time efficient but that the slide and cryoEMBEDDER methods require less cutting into the specimen to obtain a complete section. The cryoEMBEDDER device used in this study was loaned by cryoEMBEDDER (Salt Lake City, Utah). [source] Conversion of sagebrush shrublands to exotic annual grasslands negatively impacts small mammal communitiesDIVERSITY AND DISTRIBUTIONS, Issue 5 2009Steven M. Ostoja Abstract Aim, The exotic annual cheatgrass (Bromus tectorum) is fast replacing sagebrush (Artemisia tridentata) communities throughout the Great Basin Desert and nearby regions in the Western United States, impacting native plant communities and altering fire regimes, which contributes to the long-term persistence of this weedy species. The effect of this conversion on native faunal communities remains largely unexamined. We assess the impact of conversion from native perennial to exotic annual plant communities on desert rodent communities. Location, Wyoming big sagebrush shrublands and nearby sites previously converted to cheatgrass-dominated annual grasslands in the Great Basin Desert, Utah, USA. Methods, At two sites in Tooele County, Utah, USA, we investigated with Sherman live trapping whether intact sagebrush vegetation and nearby converted Bromus tectorum -dominated vegetation differed in rodent abundance, diversity and community composition. Results, Rodent abundance and species richness were considerably greater in sagebrush plots than in cheatgrass-dominated plots. Nine species were captured in sagebrush plots; five of these were also trapped in cheatgrass plots, all at lower abundances than in the sagebrush. In contrast, cheatgrass-dominated plots had no species that were not found in sagebrush. In addition, the site that had been converted to cheatgrass longer had lower abundances of rodents than the site more recently converted to cheatgrass-dominated plots. Despite large differences in abundances and species richness, Simpson's D diversity and Shannon-Wiener diversity and Brillouin evenness indices did not differ between sagebrush and cheatgrass-dominated plots. Main conclusions, This survey of rodent communities in native sagebrush and in converted cheatgrass-dominated vegetation suggests that the abundances and community composition of rodents may be shifting, potentially at the larger spatial scale of the entire Great Basin, where cheatgrass continues to invade and dominate more landscape at a rapid rate. [source] Relation between flow, surface-layer armoring and sediment transport in gravel-bed riversEARTH SURFACE PROCESSES AND LANDFORMS, Issue 8 2008John Pitlick Abstract This study investigates trends in bed surface and substrate grain sizes in relation to reach-scale hydraulics using data from more than 100 gravel-bed stream reaches in Colorado and Utah. Collocated measurements of surface and substrate sediment, bankfull channel geometry and channel slope are used to examine relations between reach-average shear stress and bed sediment grain size. Slopes at the study sites range from 0·0003 to 0·07; bankfull depths range from 0·2 to 5 m and bankfull widths range from 2 to 200 m. The data show that there is much less variation in the median grain size of the substrate, D50s, than there is in the median grain size of the surface, D50; the ratio of D50 to D50s thus decreases from about four in headwater reaches with high shear stress to less than two in downstream reaches with low shear stress. Similar trends are observed in an independent data set obtained from measurements in gravel-bed streams in Idaho. A conceptual quantitative model is developed on the basis of these observations to track differences in bed load transport through an idealized stream system. The results of the transport model suggest that downstream trends in total bed load flux may vary appreciably, depending on the assumed relation between surface and substrate grain sizes. Copyright © 2007 John Wiley & Sons, Ltd. [source] Assessing ecosystem threats from global and regional change: hierarchical modeling of risk to sagebrush ecosystems from climate change, land use and invasive species in Nevada, USAECOGRAPHY, Issue 1 2010Bethany A. Bradley Global change poses significant challenges for ecosystem conservation. At regional scales, climate change may lead to extensive shifts in species distributions and widespread extirpations or extinctions. At landscape scales, land use and invasive species disrupt ecosystem function and reduce species richness. However, a lack of spatially explicit models of risk to ecosystems makes it difficult for science to inform conservation planning and land management. Here, I model risk to sagebrush (Artemisia spp.) ecosystems in the state of Nevada, USA from climate change, land use/land cover change, and species invasion. Risk from climate change is based on an ensemble of 10 atmosphere-ocean general circulation model (AOGCM) projections applied to two bioclimatic envelope models (Mahalanobis distance and Maxent). Risk from land use is based on the distribution of roads, agriculture, and powerlines, and on the spatial relationships between land use and probability of cheatgrass Bromus tectorum invasion in Nevada. Risk from land cover change is based on probability and extent of pinyon-juniper (Pinus monophylla; Juniperus spp.) woodland expansion. Climate change is most likely to negatively impact sagebrush ecosystems at the edges of its current range, particularly in southern Nevada, southern Utah, and eastern Washington. Risk from land use and woodland expansion is pervasive throughout Nevada, while cheatgrass invasion is most problematic in the northern part of the state. Cumulatively, these changes pose major challenges for conservation of sagebrush and sagebrush obligate species. This type of comprehensive assessment of ecosystem risk provides managers with spatially explicit tools important for conservation planning. [source] Idol and Gift in VolponeENGLISH LITERARY RENAISSANCE, Issue 3 2005KATHARINE EISAMAN MAUS For their helpful comments on a draft of this essay, I thank John Portmann, Michael Murrin, Howard Marchitello and members of audiences to my lecture version of this material, as presented at the University of Maryland, Cambridge University, University of Virginia, University of Newcastle, University of Liverpool, University of Leeds, the Shakespeare Institute of the University of Birmingham at Stratford-upon-Avon, the Pittsburgh Renaissance Consortium, and the University of Utah. [source] Selenium and mercury concentrations in California gulls breeding on the Great Salt Lake, Utah, USAENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 2 2009Michael R. Conover Abstract We examined selenium (Se) and mercury (Hg) concentrations in adult California gulls (Larus californicus) nesting on the Great Salt Lake, Utah, USA, during 2006 and 2007. During 2006, the mean Se concentration (± standard error) was 18.1 ± 1.5 ,g/g in blood on a dry-weight basis and 8.1 ± 0.4 ,g/g in liver. During 2007, Se concentrations were 15.7 ± 1.5 ,g/g in blood and 8.3 ± 0.4 ,g/g in liver; Hg concentrations were 2.4 ± 0.3 ,g/g in blood and 4.1 ± 0.5 ,g/g in liver. Gulls collected from a freshwater colony located within the watershed of the Great Salt Lake had similar levels of Se in the blood and liver as gulls collected on the Great Salt Lake but lower Hg concentrations. Body mass of adult gulls was not correlated with Se or Hg concentrations in their blood or liver. Selenium concentration in California gull eggs collected during 2006 was 3.0 ± 0.10 ,g/g. Of 72 eggs randomly collected from Great Salt Lake colonies, only one was infertile, and none of the embryos exhibited signs of malposition or deformities. We examined 100 newly hatched California gull chicks from Great Salt Lake colonies for teratogenesis; all chicks appeared normal. Hence, the elevated Se and Hg concentrations in adult gulls nesting on the Great Salt Lake did not appear to impair gulls' health or reproductive ability. [source] Borrower- and Mortgage-Related Factors Associated With FHA ForeclosuresFAMILY & CONSUMER SCIENCES RESEARCH JOURNAL, Issue 3 2006Lucy Delgadillo The study identifies which household factors contribute to the likelihood of foreclosure by responding to the question: What borrower-related and mortgage-related factors are correlated with home foreclosure? Data used are from an inventory of active and foreclosed FHAhomes in Utah from the years 2000 to 2001. The sample consisted of 179 cases. The borrower-related factors included age of borrower, job tenure, self-employed, race of borrower, first-time homebuyer, number of dependents, homeownership counseling, and borrower's income. The mortgage-related factors included loan-to-value ratio, payment-to-income ratio, back-end ratio, gift amount, size of down payment, and interest rate. Results revealed that race, front-end ratio, and interest rate were statistically significant factors associated with the probability of foreclosure. The multiple interaction regression model indicated that the interaction between race and front-end ratio was statistically significant, which suggests that the effect of front-end ratio differs between Whites and non-Whites. [source] A Model of Factors Correlated to Homeownership: The Case of UtahFAMILY & CONSUMER SCIENCES RESEARCH JOURNAL, Issue 1 2001Lucy Delgadillo This article examines the relationship between homeownership and socioeconomic, demographic, and market factors in Utah. Units of analyses were census-designated places. The goal was to provide a model that can be replicated by housing specialists and consumer scientists to gain a better understanding of how homeownership (dependent variable) differs from place to place and how this variation relates to socioeconomic index, population density, affordability ratio, and the median value of owner occupied housing units (independent variables). The 1990 data set was analyzed using bivariate and multivariate analyses. Homeownership percentages were regressed on the linear combination of the socioeconomic scale, log of population density, and affordability ratios. Log of population density was the factor that explained most of the variance. The interaction equation slightly improved the explanatory power, accounting for more than 50% of the variance. [source] Diversity of sulfate-reducing bacteria from an extreme hypersaline sediment, Great Salt Lake (Utah)FEMS MICROBIOLOGY ECOLOGY, Issue 2 2007Kasper Urup Kjeldsen Abstract The diversity of sulfate-reducing bacteria (SRB) inhabiting the extreme hypersaline sediment (270 g L,1 NaCl) of the northern arm of Great Salt Lake was studied by integrating cultivation and genotypic identification approaches involving PCR-based retrieval of 16S rRNA and dsrAB genes, the latter encoding major subunits of dissimilatory (bi) sulfite reductase. The majority (85%) of dsrAB sequences retrieved directly from the sediment formed a lineage of high (micro) diversity affiliated with the genus Desulfohalobium, while others represented novel lineages within the families Desulfohalobiaceae and Desulfobacteraceae or among Gram-positive SRB. Using the same sediment, SRB enrichment cultures were established in parallel at 100 and at 190 g L,1 NaCl using different electron donors. After 5,6 transfers, dsrAB and 16S rRNA gene-based profiling of these enrichment cultures recovered a SRB community composition congruent with the cultivation-independent profiling of the sediment. Pure culture representatives of the predominant Desulfohalobium -related lineage and of one of the Desulfobacteraceae -affilated lineages were successfully obtained. The growth performance of these isolates and of the enrichment cultures suggests that the sediment SRB community of the northern arm of Great Salt Lake consists of moderate halophiles, which are salt-stressed at the in situ salinity of 27%. [source] The MLH1 ,93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancerGENES, CHROMOSOMES AND CANCER, Issue 10 2008Wade S. Samowitz The MLH1 ,93 G>A promoter polymorphism has been reported to be associated with an increased risk of microsatellite unstable colorectal cancer. Other than microsatellite instability, however, the genetic and most epigenetic changes of tumors associated with this polymorphism have not been studied. We evaluated associations between the ,93 G>A polymorphism and CpG island methylator phenotype (CIMP), BRAF V600E mutations, and MLH1 methylation in tumors from a sample of 1,211 individuals with colon cancer and 1,968 controls from Utah, Northern California, and Minnesota. The ,93 G>A polymorphism was determined by the five prime nuclease assay. CIMP was determined previously by methylation-specific PCR of CpG islands in MLH1, methylated in tumors (MINT)1, MINT2, MINT31, and CDKN2A (p16). The BRAF V600E mutation was determined by sequencing exon 15. The MLH1 ,93 G>A promoter polymorphism was associated with CIMP (odds ratio (OR) 3.44, 95% confidence interval (CI) 1.85, 6.42), MLH1 methylation (OR 4.16, 95%CI 2.20, 7.86), BRAF mutations (OR 4.26, 95%CI 1.83, 9.91), and older age at diagnosis (OR 3.65, 95%CI 2.08, 6.39) in microsatellite unstable tumors. These associations were not observed in stable tumors. Increased age at diagnosis and tumor characteristics of microsatellite unstable tumors associated with MLH1 ,93 G>A suggests the polymorphism is acting at a relatively late stage of colorectal carcinogenesis to drive CIMP+ tumors down the microsatellite instability pathway. © 2008 Wiley-Liss, Inc. [source] Evaluation of soluble benzene migration in the Uinta BasinGEOFLUIDS (ELECTRONIC), Issue 2 2005Y. ZHANG Abstract Field sampling and mathematical modeling are used to study the long-distance transport and attenuation of petroleum-derived benzene in the Uinta Basin, Utah. Benzene concentration was measured from oil and oil field formation waters of the Altamont-Bluebell and Pariette Bench oil fields in the basin. It was also measured from springs located in the regional groundwater discharge areas, hydraulically down-gradient from the oil fields sampled. The average benzene concentration in oils and co-produced waters is 1946 and 4.9 ppm at the Altamont-Bluebell field and 1533 and 0.6 ppm at the Pariette Bench field, respectively. Benzene concentration is below the detection limit in all springs sampled. Mathematical models are constructed along a north,south trending transect across the basin through both fields. The models represent groundwater flow, heat transfer and advective/dispersive benzene transport in the basin, as well as benzene diffusion within the oil reservoirs. The coupled groundwater flow and heat transfer model is calibrated using available thermal and hydrologic data. We were able to reproduce the observed excess fluid pressure within the lower Green River Formation and the observed convective temperature anomalies across the northern basin. Using the computed best-fit flow and temperature, the coupled transport model simulates water washing of benzene from the oil reservoirs. Without the effect of benzene attenuation, dissolved benzene reaches the regional groundwater discharge areas in measurable concentration (>0.01 ppm); with attenuation, benzene concentration diminishes to below the detection limit within 1,4 km from the reservoirs. Attenuation also controls the amount of water washing over time. In general, models that represent benzene attenuation in the basin produce results more consistent with field observations. [source] An exhumed palaeo-hydrocarbon migration fairway in a faulted carrier system, Entrada Sandstone of SE Utah, USAGEOFLUIDS (ELECTRONIC), Issue 3 2001I. R. Garden Abstract The Moab Anticline, east-central Utah, is an exhumed hydrocarbon palaeo-reservoir which was supplied by hydrocarbons that migrated from the Moab Fault up-dip towards the crest of the structure beneath the regional seal of the Tidwell mudstone. Iron oxide reduction in porous, high permeability aeolian sandstones records the secondary migration of hydrocarbons, filling of traps against small sealing faults and spill pathways through the Middle Jurassic Entrada Sandstone. Hydrocarbons entered the Entrada Sandstone carrier system from bends and other leak points on the Moab Fault producing discrete zones of reduction that extend for up to 400 m from these leak points. They then migrated in focused stringers, 2,5 m in height, to produce accumulations on the crest of the anticline. Normal faults on the anticline were transient permeability barriers to hydrocarbon migration producing a series of small compartmentalized accumulations. Exsolution of CO2 as local fault seals were breached resulted in calcite cementation on the up-dip side of faults. Field observations on the distribution of iron oxide reduction and calcite cements within the anticline indicate that the advancing reduction fronts were affected neither by individual slip bands in damage zones around faults nor by small faults with sand: sand juxtapositions. Faults with larger throws produced either sand: mudstone juxtapositions or sand: sand contacts and fault zones with shale smears. Shale-smeared fault zones provided seals to the reducing fluid which filled the structural traps to spill points. [source] EARLY INTELLECTUAL INFLUENCES ON D. W. MEINIG: A FORMER STUDENT'S FOND MEMORIES,GEOGRAPHICAL REVIEW, Issue 3 2009BRUCE BIGELOW ABSTRACT. As an undergraduate and graduate student in the 1940s and a young professor at the University of Utah in the 1950s, D. W. Meinig was influenced by a number of scholars. They included six historians, three geographers, two anthropologists, and two philosophers. I identify the influence of the thirteen scholars on Meinig's major achievements: the culture area model, geography as an art, the historical imperative for geography, cultures and civilizations, and geopolitics and imperialism. [source] Regional monitoring of infrasound events using multiple arrays: application to Utah and Washington StateGEOPHYSICAL JOURNAL INTERNATIONAL, Issue 1 2008Stephen J. Arrowsmith SUMMARY In this paper, we present an integrated set of algorithms for the automatic detection, association, and location of low-frequency acoustic events using regional networks of infrasound arrays. Here, low-frequency acoustic events are characterized by transient signals, which may arise from a range of natural and anthropogenic sources, examples of which include (but are not limited to) earthquakes, volcanic eruptions, explosions, rockets and bolides. First, we outline a new technique for detecting infrasound signals that works successfully in the presence of correlated noise. We use an F -statistic, sequentially adapted to ambient noise conditions, in order to obtain detections at a given statistical significance while accounting for real background noise. At each array, individual arrivals are then grouped together based on measured delay-times and backazimuths. Each signal is identified as either a first or later arrival. First arrivals at spatially separated arrays are then associated using a grid-search method to form events. Preliminary event locations are calculated from the geographic means and spreads of grid nodes associated with each event. We apply the technique to regional infrasound networks in Utah and Washington State. In Utah, over a period of approximately 1 month, we obtain a total of 276 events recorded at three arrays in a geographic region of 6 × 4°. For four ground-truth explosions in Utah, the automatic algorithm detects, associates, and locates the events within an average offset of 5.4 km to the actual explosion locations. In Washington State, the algorithm locates numerous events that are associated with a large coalmine in Centralia, Washington. An example mining-explosion from Centralia is located within 8.2 km of the mine. The methodology and results presented here provide an initial framework for assessing the capability of infrasound networks for regional infrasound monitoring, in particular by quantifying detection thresholds and localization errors. [source] 3D imaging of a reservoir analogue in point bar deposits in the Ferron Sandstone, Utah, using ground-penetrating radarGEOPHYSICAL PROSPECTING, Issue 3 2004Xiaoxian Zeng ABSTRACT Most existing reservoir models are based on 2D outcrop studies; 3D aspects are inferred from correlation between wells, and so are inadequately constrained for reservoir simulations. To overcome these deficiencies, we have initiated a multidimensional characterization of reservoir analogues in the Cretaceous Ferron Sandstone in Utah. Detailed sedimentary facies maps of cliff faces define the geometry and distribution of reservoir flow units, barriers and baffles at the outcrop. High-resolution 2D and 3D ground-penetrating radar (GPR) images extend these reservoir characteristics into 3D to allow the development of realistic 3D reservoir models. Models use geometric information from mapping and the GPR data, combined with petrophysical data from surface and cliff-face outcrops, and laboratory analyses of outcrop and core samples. The site of the field work is Corbula Gulch, on the western flank of the San Rafael Swell, in east-central Utah. The outcrop consists of an 8,17 m thick sandstone body which contains various sedimentary structures, such as cross-bedding, inclined stratification and erosional surfaces, which range in scale from less than a metre to hundreds of metres. 3D depth migration of the common-offset GPR data produces data volumes within which the inclined surfaces and erosional surfaces are visible. Correlation between fluid permeability, clay content, instantaneous frequency and instantaneous amplitude of the GPR data provides estimates of the 3D distribution of fluid permeability and clay content. [source] G-substrate gene promoter SNP (,1323T>C) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: Intra-familial association study in an eight-generation hyperlipidemic kindredGERIATRICS & GERONTOLOGY INTERNATIONAL, Issue 2 2004Yukiko Nobe Background: Plasma lipid and lipoprotein generally reflect the complex influences of multiple genetic loci, for instance, even familial hypercholesterolemia (FH), a representative example of monogenic hyperlipidemia, often presents with phenotypic heterogeneity. Methods: In the course of investigating familial coronary artery disease in Utah, we studied 160 members of an eight-generation extended family of FH, to examine possible genetic modification of lipoprotein phenotype by ,modifier locus'. G-substrate (GSBS) is an endogenous substrate for cGMP-dependent protein kinase. We carried out an intrafamilial correlation analysis of modifier effect of ,1323T>C substitution in the GSBS gene among 85 LDLR-mutation carriers and 75 non-carriers. Results: In the LDLR - mutation carriers, the plasma cholesterol levels were highest among ,1323C homozygotes (mean ± SD = 454 ± 101 mg/dL), lowest among ,1323T homozygotes (mean ± SD, 307 ± 72 mg/dL) and intermediate among ,1323T/C heterozygotes (mean ± SD, 314 ± 62 mg/dL; P = 0.015). Similarly, in the LDLR-mutation carriers, the plasma triglyceride levels were highest among ,1323C homozygotes (mean ± SD, 371 ± 381 mg/dL), lowest among ,323T homozygotes (mean ± SD, 171 ± 94 mg/dL), and intermediate among ,1323T/C heterozygotes (mean ± SD, 218 ± 130 mg/dL; P = 0.003). No such gene-interactive effect was observed among non-carriers of the LDLR-mutation. Conclusion: These results indicate a significant modification of the phenotype of FH with defective LDLR allele, by GSBS-1323C allele in the kindred studied. [source] International conference on prejudice and conflict Salt Lake City, Utah, December 2,4, 2005, pre-conference December 1, 2005INTERNATIONAL JOURNAL OF APPLIED PSYCHOANALYTIC STUDIES, Issue 3 2005Article first published online: 24 JAN 200 [source] Thymidylate synthase polymorphisms and colon cancer: Associations with tumor stage, tumor characteristics and survivalINTERNATIONAL JOURNAL OF CANCER, Issue 10 2007Karen Curtin Abstract Thymidylate synthase (TS) is a key enzyme in folate metabolism, a pathway that is important in colorectal carcinogenesis. We investigated the role of functional polymorphisms in the TS 5,-UTR promoter enhancer region (TSER, 3 or 2 repeats of a 28-bp sequence) and the 3,-UTR (1494delTTAAAG) and their association with colon tumor characteristics, including tumor stage and acquired mutations in p53, Ki- ras and microsatellite instability. Data from a population-based incident case,control colon cancer study in northern California, Utah and Minnesota (1,206 cases, 1,962 controls) was analyzed using unordered polytomous logistic regression models. In both men and women, individuals with variant TS alleles were at reduced risk of having an advanced stage tumor (metastatic disease: OR = 0.35, 95% CI: 0.2,0.6 vs. wildtype TSER and 3,-UTR). Stage-adjusted survival did not differ by genotype. Men with 1 or 2 variant alleles in both the TSER and 3,-UTR genotypes had a 50% reduced risk of a p53 -positive tumor (OR = 0.5, 95% CI: 0.3,0.9 vs. homozygous wildtype TSER and 3,-UTR). Women with 1 or 2 variant alleles for either the TSER or 3,-UTR polymorphism had reduced risk of having any colon tumor that did not vary by mutation status. This study provides some support for associations between TS genotype and colon cancer tumor characteristics. © 2007 Wiley-Liss, Inc. [source] The persistence of neuropsychiatric symptoms in dementia: the Cache County StudyINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 1 2004Martin Steinberg Abstract Objective To estimate the 18-month persistence of neuropsychiatric symptoms in dementia in a population-based sample, and to compare the severity of neuropsychiatric symptoms at baseline to the severity at 18-month follow-up. Methods A population-based sample of 329 residents of Cache County, Utah, diagnosed with dementia was rated on the Neuropsychiatric Inventory (NPI). Of the 204 participants with neuropsychiatric symptoms at baseline (defined as total NPI score >0), NPI data were obtained approximately 18 months later on 117 who were alive and available for follow-up. Results Eighty-one percent of those with neuropsychiatric symptoms at baseline (defined as total NPI score>0) continued to have at least one symptom at follow-up. Sixty-seven percent of participants with a clinically significant total NPI score (defined as ,;4) at baseline continued to have a clinically significant total NPI score at follow-up. Among the ten neuropsychiatric domains assessed at baseline, delusions persisted in 65.5% of individuals, followed by depression (58.3%), and aberrant motor behavior (55.6%), while hallucinations and disinhibition persisted in only 25.0% and 11.1% respectively. In participants who were symptomatic at both baseline and follow-up, the mean severity scores at the two observation points were comparable in all ten neuropsychiatric domains. Conclusions Neuropsychiatric symptoms in dementia overall were highly persistent. Among those in whom symptoms did persist, symptom severity a year and a half later appeared to be comparable. Copyright © 2004 John Wiley & Sons, Ltd. [source] Ten Dimensions of Health and Their Relationships with Overall Self-Reported Health and Survival in a Predominately Religiously Active Elderly Population: The Cache County Memory StudyJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 2 2006Truls Østbye MD OBJECTIVES: To document the extent of healthy aging along 10 different dimensions in a population known for its longevity. DESIGN: A cohort study with baseline measures of overall self-reported health and health along 10 specific dimensions; analyses investigated the 10 dimensions as predictors of self-reported health and 10-year mortality. SETTING: Cache County, Utah, which is among the areas with the highest conditional life expectancy at age 65 in the United States. PARTICIPANTS: Inhabitants of Cache County aged 65 and older (January 1, 1995). MEASUREMENTS: Self-reported overall health and 10 specific dimensions of healthy aging: independent living, vision, hearing, activities of daily living, instrumental activities of daily living, absence of physical illness, cognition, healthy mood, social support and participation, and religious participation and spirituality. RESULTS: This elderly population was healthy overall. With few exceptions, 80% to 90% of persons aged 65 to 75 were healthy according to each measure used. Prevalence of excellent and good self-reported health decreased with age, to approximately 60% in those aged 85 and older. Even in the oldest old, the majority of respondents were independent in activities of daily living. Although vision, hearing, and mood were significant predictors of overall self-reported health in the final models, age, sex, and cognition were significant only in the final survival models. CONCLUSION: This population has a high prevalence of most factors representing healthy aging. The predictors of overall self-reported health are distinct from the predictors of survival in this age group and, being potentially modifiable, are amenable to clinical and public health efforts. [source] Apolipoprotein E Genotype and Mortality: Findings from the Cache County StudyJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 6 2005Kathleen M. Hayden PhD Objectives: To evaluate the association between apolipoprotein E (apo E) ,4 and mortality, the population attributable risk for mortality with ,4, and relative contributions of cardiovascular disease (CVD) and Alzheimer's disease (AD). Design: Population-based cohort study. Setting: Community-based. Participants: Permanent residents of Cache County, Utah, aged 65 and older as of January 1, 1995. Measurements: Participants were genotyped at the apo E locus using buccal-swab deoxyribonucleic acid. Cardiovascular health was ascertained using self- or proxy-report interviews at participants' residences. AD was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised, and National Institute of Neurological and Communicative Disorders and Stroke,Alzheimer's Disease and Related Disorders criteria. Utah Department of Vital Statistics quarterly reports were reviewed to identify participants who died. Results: Crude evaluations showed nonsignificantly greater risk of death for ,2/2 (hazard ratio (HR)=1.66, 95% confidence interval (CI)=0.92,2.76) and ,3/4 (HR=1.11, 95% CI=0.97,1.26) genotypes and significantly greater risk for ,4/4 (HR=1.48, 95% CI=1.09,1.96). After adjustment for age, age2, sex, and education, risks increased to 1.98 (95% CI=1.08,3.35), 1.28 (95% CI=1.12,1.46), and 2.02 (95% CI=1.47,2.71), respectively, compared with ,3/3 genotypes. Adjustment for presence of any CVD did not change the risk of death for ,3/4 and ,4/4. Adjustment for AD reduced the risk of death for ,3/4 (HR=1.13, 95% CI=0.99,1.30) and ,4/4 (HR=1.59, 95% CI=1.15,2.14). The population attributable risk of death for ,3/4 and ,4/4 genotypes combined is estimated at 9.6%. Conclusion: These findings suggested that the ,2/2, ,3/4, and ,4/4 genotypes have greater early mortality risks. Further analyses showed that AD partially mediates the association between ,3/4, ,4/4, and death. [source] Gene expression profiles associated with aging and mortality in humansAGING CELL, Issue 3 2009Richard A. Kerber Summary We investigated the hypothesis that gene expression profiles in cultured cell lines from adults, aged 57,97 years, contain information about the biological age and potential longevity of the donors. We studied 104 unrelated grandparents from 31 Utah CEU (Centre d'Etude du Polymorphisme Humain , Utah) families, for whom lymphoblastoid cell lines were established in the 1980s. Combining publicly available gene expression data from these cell lines, and survival data from the Utah Population Database, we tested the relationship between expression of 2151 always-expressed genes, age, and survival of the donors. Approximately 16% of 2151 expression levels were associated with donor age: 10% decreased in expression with age, and 6% increased with age. Cell division cycle 42 (CDC42) and CORO1A exhibited strong associations both with age at draw and survival after draw (multiple comparisons-adjusted Monte Carlo P -value < 0.05). In general, gene expressions that increased with age were associated with increased mortality. Gene expressions that decreased with age were generally associated with reduced mortality. A multivariate estimate of biological age modeled from expression data was dominated by CDC42 expression, and was a significant predictor of survival after blood draw. A multivariate model of survival as a function of gene expression was dominated by CORO1A expression. This model accounted for approximately 23% of the variation in survival among the CEU grandparents. Some expression levels were negligibly associated with age in this cross-sectional dataset, but strongly associated with inter-individual differences in survival. These observations may lead to new insights regarding the genetic contribution to exceptional longevity. [source] Targeted sugar provision promotes parasitism of the cereal leaf beetle Oulema melanopusAGRICULTURAL AND FOREST ENTOMOLOGY, Issue 1 2010Edward W. Evans 1Parasitoids may often lack access to sugar (e.g. floral nectar) in agricultural settings. Strategically timed spraying of host plants with sugar solution may provide one means of enhancing parasitism at the same time as minimizing nontarget effects (e.g. benefiting the pest itself). 2Sucrose was sprayed in wheat fields of northern Utah (U.S.A.) to assess the effects on parasitism of the cereal leaf beetle Oulema melanopus by the larval parasitoid Tetrastichus julis. 3Early-season sugar provisioning, when larvae of the pest were first hatching and parasitoid adults were newly emerged, did not affect the numbers of cereal leaf beetle larvae that matured in treated plots but increased parasitism rates of beetle larvae by four-fold in 2006 and by seven-fold in 2007. 4No net influx of adult parasitoids into plots was detected after the application of sugar. Locally-emerging parasitoids may have spent less time searching for their own food needs versus hosts. A laboratory experiment also confirmed that access to sucrose significantly increased parasitoid longevity. 5The field experimental results obtained demonstrate that applications of sugar, implemented to target a key time of the growing season when benefits are maximized for parasitoids and minimized for their hosts, can strongly promote parasitism of the cereal leaf beetle in wheat fields. [source] Reactive flow of mixed CO2,H2O fluid and progress of calc-silicate reactions in contact metamorphic aureoles: insights from two-dimensional numerical modellingJOURNAL OF METAMORPHIC GEOLOGY, Issue 7 2003X. Cui Abstract Previous models of hydrodynamics in contact metamorphic aureoles assumed flow of aqueous fluids, whereas CO2 and other species are also common fluid components in contact metamorphic aureoles. We investigated flow of mixed CO2,H2O fluid and kinetically controlled progress of calc-silicate reactions using a two-dimensional, finite-element model constrained by the geological relations in the Notch Peak aureole, Utah. Results show that CO2 strongly affects fluid-flow patterns in contact aureoles. Infiltration of magmatic water into a homogeneous aureole containing CO2,H2O sedimentary fluid facilitates upward, thermally driven flow in the inner aureole and causes downward flow of the relatively dense CO2 -poor fluid in the outer aureole. Metamorphic CO2 -rich fluid tends to promote upward flow in the inner aureole and the progress of devolatilization reactions causes local fluid expulsion at reacting fronts. We also tracked the temporal evolution of P-T-XCO2conditions of calc-silicate reactions. The progress of low- to medium-grade (phlogopite- to diopside-forming) reactions is mainly driven by heat as the CO2 concentration and fluid pressure and temperature increase simultaneously. In contrast, the progress of the high-grade wollastonite-forming reaction is mainly driven by infiltration of chemically out-of-equilibrium, CO2 -poor fluid during late-stage heating and early cooling of the inner aureole and thus it is significantly enhanced when magmatic water is involved. CO2 -rich fluid dominates in the inner aureole during early heating, whereas CO2 -poor fluid prevails at or after peak temperature is reached. Low-grade metamorphic rocks are predicted to record the presence of CO2 -rich fluid, and high-grade rocks reflect the presence of CO2 -poor fluid, consistent with geological observations in many calc-silicate aureoles. The distribution of mineral assemblages predicted by our model matches those observed in the Notch Peak aureole. [source] Shoreline tufa and tufaglomerate from Pleistocene Lake Bonneville, Utah, USA: stable isotopic and mineralogical records of lake conditions, processes, and climate,JOURNAL OF QUATERNARY SCIENCE, Issue 1 2005Stephen T. Nelson Abstract Shoreline carbonate deposits of Pleistocene Lake Bonneville record the conditions and processes within the lake, including the evaporative balance as well as vertical and lateral chemical and isotopic gradients. Tufas (swash-zone) and tufaglomerates (cemented, subaqueous colluvium or beachrock) on multiple, well-developed shorelines near the Silver Island Range, Utah, also present an opportunity to examine physicochemical lake processes through time. Three shorelines are represented by carbonate deposits, including the 23,20,ka Stansbury stage, 15,14.5,ka Bonneville stage, and 14.5,14,ka Provo stage. Mean ,18OVSMOW values of all three shorelines are statistically indistinguishable (,,,27,±,1,), when a few Bonneville samples of unusual composition are neglected. However, differences in primary carbonate mineralogy indicate that the correspondence is an artefact of the different fractionation factors between calcite or aragonite and water. Second, in order to sustain a much smaller, shallower lake during the colder Stansbury stage, the climate must have also been relatively dry. Third, ,18O values in tufa are higher than tufaglomerate by ,,,0.5,, consistent with greater evaporative enrichment of lake water in the swash zone. Fourth, mean ,13C values for the Provo, Stansbury and Bonneville shorelines (4.4, 5.0 and 5.2,, respectively) show that carbon species were dominated by atmospheric exchange, with the variations produced by differences in the oxidation of organic matter. Comparisons of shoreline carbonates with deep-lake marls of the same approximate age indicate that shoreline carbonate was much higher in ,13C and ,18O values (both ,,2.5,) during Bonneville time, whereas isotopic differences were minor (both ,,1,) in Stansbury time. In particular, the Bonneville stage may have sustained large vertical or lateral isotopic gradients due to evaporative enrichment effects on ,18O values. In contrast, the lake during the much shallower Stansbury stage may have been well mixed. Differences in the primary mineralogy (Stansbury and Bonneville, aragonite,>,calcite; Provo, calcite,>,aragonite) reflect profound differences in lake chemistry in terms of open versus closed-basin lakes. The establishment of a continuous outlet during Provo time probably reduced the Mg2+/Ca2+ ratio of lake water. Curiously, regardless of primary mineralogy, tufaglomerate cements are enriched in Na+ and Cl, and depleted in Mg2+ relative to capping tufa of the same age. This probably reflects vital or kinetic effects in the swash zone (tufa). We suspect that ,abiotic' effects may have been important in the dark pore space of developing tufaglomerate, where the absence of light suppressed photosynthesis. Copyright © 2005 John Wiley & Sons, Ltd. [source] Evaluation of the Utah Student Injury Reporting SystemJOURNAL OF SCHOOL HEALTH, Issue 2 2002Rebecca S. Spicer ABSTRACT: The Utah Student Injury Reporting System (SIRS), implemented in 1984 to monitor injuries to students in grades K-12 in Utah schools, has served as a model for surveillance systems created by other states and some European countries. This paper evaluates the Utah experience in developing and administering the SIRS. The evaluation identifies usefulness of the system, discusses the sensitivity of the system in detecting school injuries, estimates the system's costs, and provides suggestions to other states and districts interested in building a cost-effective and efficient surveillance instrument. (J Sch Health. 2002;72(2):47-50) [source] "The Defendant Has Seemed to Live a Charmed Life": Hopt v. Utah: Territorial Justice, The Supreme Court of the United States, and Late Nineteenth-Century Death Penalty JurisprudenceJOURNAL OF SUPREME COURT HISTORY, Issue 1 2000Sidney L. Harring On March 7, 1887, the Supreme Court of the United States decided Fred Hopt's fourth appeal to that Court. The Utah Territory murderer's conviction had been reversed three times over seven years-his "charmed life"-but this time both his luck and his legal argument had run out: his fourth conviction was upheld. Justice Stephen J. Field dismissed Hopt's four major claims: that several members of the jury were improperly seated in spite of bias; that a doctor's evidence of cause of death was beyond the scope of his expertise; that the trial judge's "reasonable doubt" jury instruction was inadequate; and that the prosecutor's reference to the "many times the case had been before the courts" was prejudicial. Five months later, on August 11, Hopt was executed by a firing squad in the yard of the Utah Penitentiary. Hopt was only one of over two thousand convicted criminals, mostly murderers, who were legally executed in the United States in the two decades between 1880 and 1900. However, his defense team of court-appointed Salt Lake City lawyers had kept him alive for seven years. During that time he had four jury trials, four appeals to the Supreme Court of Utah Territory, and four appeals to the Supreme Court of the United States. He is the only death penalty litigant ever to be the subject of four full opinions of the Supreme Court of the United States. [source] ARSENIC IN THE SHALLOW GROUND WATERS OF CONTERMINOUS UNITED STATES: ASSESSMENT, HEALTH RISKS, AND COSTS FOR MCL COMPLIANCE,JOURNAL OF THE AMERICAN WATER RESOURCES ASSOCIATION, Issue 2 2006Navin Kumar C. Twarakavi ABSTRACT: A methodology consisting of ordinal logistic regression (OLR) is used to predict the probability of occurrence of arsenic concentrations in different threshold limits in shallow ground waters of the conterminous United States (CONUS) subject to a set of influencing variables. The analysis considered a number of maximum contaminant level (MCL) options as threshold values to estimate the probabilities of occurrence of arsenic in ranges defined by a given MCL of 3, 5, 10, 20, and 50 ,g/l and a detection limit of 1 ,g/l. The fit between the observed and predicted probability of occurrence was around 83 percent for all MCL options. The estimated probabilities were used to estimate the median background concentration of arsenic in the CONUS. The shallow ground water of the western United States is more vulnerable than the eastern United States. Arizona, Utah, Nevada, and California in particular are hotspots for arsenic contamination. The risk assessment showed that counties in southern California, Arizona, Florida, and Washington and a few others scattered throughout the CONUS face a high risk from arsenic exposure through untreated ground water consumption. A simple cost effectiveness analysis was performed to understand the household costs for MCL compliance in using arsenic contaminated ground water. The results showed that the current MCL of 10 ,g/l is a good compromise based on existing treatment technologies. [source] Aspen succession and nitrogen loading: a case for epiphytic lichens as bioindicators in the Rocky Mountains, USAJOURNAL OF VEGETATION SCIENCE, Issue 3 2009Paul C. Rogers Abstract Question: Can lichen communities be used to assess short- and long-term factors affecting seral quaking aspen (Populus tremuloides) communities at the landscape scale? Location: Bear River Range, within the Rocky Mountains, in northern Utah and southern Idaho, USA. Method: Forty-seven randomly selected mid-elevation aspen stands were sampled for lichens and stand conditions. Plots were characterized according to tree species cover, basal area, stand age, bole scarring, tree damage, and presence of lichen species. We also recorded ammonia emissions with passive sensors at 25 urban and agricultural sites throughout an adjacent populated valley upwind of the forest stands. Nonmetric multidimensional scaling (NMS) ordination was used to evaluate an array of 20 variables suspected to influence lichen communities. Results: In NMS, forest succession explained most variance in lichen composition and abundance, although atmospheric nitrogen from local agricultural and urban sources also significantly influenced the lichen communities. Abundance of nitrophilous lichen species decreased with distance from peak ammonia sources and the urban center in all aspen succession classes. One lichen, Phaeophyscia nigricans, was found to be an effective bioindicator of nitrogen loading. Conclusions: Lichen communities in this landscape assessment of aspen forests showed clear responses to long-term (stand succession) and short-term (nitrogen deposition) influences. At the same time, several environmental factors (e.g. tree damage and scarring, distance to valley, topography, and stand age) had little influence on these same lichen communities. We recommend further use of epiphytic lichens as bioindicators of dynamic forest conditions. [source] | ||||||||||||||||||||||||||||||||||