Urban Swedish Population (urban + swedish_population)

Distribution by Scientific Domains


Selected Abstracts


Incidence and risk of venous thromboembolism in patients with verified arterial thrombosis: a population study based on 23 796 consecutive autopsies

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 9 2006
Å. ELIASSON
Summary.,Background:,The relationship between atherothrombotic disease and venous thromboembolism (VTE) remains unclear. Patients and methods:,In a cohort of 23 796 consecutive autopsies, performed using a standardized procedure and representing 84% of all in-hospital deaths between 1970 and 1982 in an urban Swedish population, we investigated the relationship between verified arterial thrombosis and VTE, with the hypothesis that patients with thrombosis in major artery segments have increased odds of VTE. Results:,We found an increased risk of VTE in patients with arterial thrombosis (Odds ratio; OR adjusted for gender and age 1.4, 95% confidence interval; CI 1.3,1.5) (P < 0.001). Patients with cervico-cranial and peripheral artery thrombosis had an excess risk even when controlling for age and major concomitant diseases. A negative association between coronary thrombosis and VTE in the univariate analysis (OR 0.7; 95% CI 0.6,0.8) (P < 0.001), was less pronounced in the multivariate analysis (OR 0.8; 95% CI 0.7,1.0) (P = 0.016). Conclusions:,A positive association between atherothrombosis and VTE was confirmed, except in patients with coronary thrombosis, where IHD as competing death cause is a possible confounder. Our findings indicate a potential for directed prevention, but may also imply similarities in etiology. [source]


A prospective longitudinal population-based study of clinical miscarriage in an urban Swedish population

BJOG : AN INTERNATIONAL JOURNAL OF OBSTETRICS & GYNAECOLOGY, Issue 2 2008
F Blohm
Objective, To describe the incidence of clinical miscarriage and to investigate the factors influencing the occurrence of clinical miscarriage. Design, Prospective study with both cross-sectional and longitudinal comparisons. Setting, City of Göteborg, Sweden. Population, Population-based study in cohorts of 19-year-old women followed longitudinally. Main outcome measures, Incidence of miscarriage and pregnancy outcome. Material and methods, A postal questionnaire was sent to women born in 1962 and resident in the city of Göteborg in 1981 (n= 656) regarding pregnancy outcome, clinical miscarriage and other reproductive health factors. Responders in 1981 were contacted again and requested to answer a similar questionnaire every fifth year up to 2001. The same process was repeated in 1991 with women born in 1972 (n= 780) with follow up of these responders in 1996 and 2001. A third cohort of 19-year-old women born in 1982 (n= 666) was interviewed in 2001. The self-reported pregnancy data were verified from hospital files. Results, Complete data were available for 341 women born in 1962 and assessed up to the age of 39 years (ever pregnant, n= 320, 94%). There were in total 887 pregnancies (live birth, n= 590, 67%; miscarriage, n= 108, 12%; legal abortion, n= 173, 20% and ectopic pregnancy, n= 16, 2%). Of the 320 ,ever pregnant' women, 80 women (25%) had experienced a miscarriage. 76.3% had experienced one miscarriage, 16.3% had two miscarriages and 7.4% had three or more miscarriages. The clinical miscarriage rates in women at different ages were as follows: 20,24 years 13.5%, 25,29 years 12.3%, 30,34 years 10.3% and 35,39 years 17.5%. The corresponding miscarriage rate in the 1972 cohort followed from 19 to 29 years of age was 11%, and in the 1982 cohort assessed at 19 years of age, the miscarriage rate was 9%. No risk factor for miscarriage could be reliably identified. Conclusions, Clinical miscarriage constituted 12% of all pregnancies, and one in four women who had been pregnant up to 39 years of age had experienced a miscarriage. Three or more miscarriages were experienced by 7.4%. The occurrence of a miscarriage was not influenced by the order of the pregnancy. [source]


Ocular changes, risk markers for eye disorders and effects of cataract surgery in elderly people: a study of an urban Swedish population followed from 70 to 97 years of age

ACTA OPHTHALMOLOGICA, Issue 2 2004
Birgitta Bergman
Abstract. Aims:, To investigate the prevalence of and potential risk factors for ocular disorders and the effects of timing of cataract surgery from age 70,97 years. Population:, A representative population sample taken from within the Gerontological and Geriatric Population Studies (H 70) in Gothenburg, Sweden (n = 958). All subjects underwent eye examinations at age 70 years in 1971 and subsequently at ages 82, 88, 95 and 97 years. All inhabitants of Gothenburg aged 95 and 97 years were invited to participate in the study. Results:, Decreased vision (visual acuity , 0.5) was found in 20% and 80% of subjects at ages 82 and 97 years, respectively. Blood folate and physical activity at age 70 years correlated positively and body mass index (BMI) negatively to visual acuity (VA) , 0.8 at ages 82 and 88 years. Smoking at age 70 years correlated to early age-related maculopathy (ARM). Cataract surgery had been performed in 40% of subjects at age 97 years. Surgery 2 years earlier led to a 15% increase in time spent with improved vision. Conclusions:, The deterioration of vision in elderly people is a major health problem, for which ,low' folate status, smoking, ,high' BMI and low physical activity are potential risk factors. Early cataract surgery is also beneficial in very old patients. [source]


A longitudinal study of visual acuity and visual rehabilitation needs in an urban Swedish population followed from the ages of 70 to 97 years of age

ACTA OPHTHALMOLOGICA, Issue 6 2002
Birgitta Bergman
ABSTRACT. Purpose:, To investigate the longitudinal change in visual acuity (VA) in the oldest members of the elderly population, to estimate future numbers of people with visual impairments, and to estimate needs for and the effects of visual rehabilitation. Methods:, In the Gerontological and Geriatric Population Studies in Gothenburg, Sweden (H 70), subjects underwent repeated eye examinations at the ages of 70, 82, 88, 95 and 97 years. Logistic regression analysis was used to estimate the probability of independent living as a function of distance VA at different ages. Results:, Rates of normal VA (, 0.8) declined from 86% of the study group at age 70 to 7% of the study group at age 95 (0% at age 97). The incidence of VA , 0.1 increased from 1.4% at age 70 to 27% (all women) at age 97. The deterioration was faster at higher ages. No statistically significant difference in best-corrected distance VA between genders was found. A substantial improvement was achieved by correcting refractive errors. There was a statistically significant correlation between distance VA and the probability of independent living at all ages except age 97. At ages 95 and 97, about 50% of the study group were able to read newspaper print with best-corrected glasses. Conclusions:, The number of old people with impaired vision will increase. People aged 80 years and older should have regular eye-screening in order to preserve vision and present conditions of living. Cataract surgery and low vision rehabilitation should be offered when the subject can still benefit from it, preferably during their 80s at the latest. [source]