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Selected Abstracts

International perspectives on workplace bullying among nurses: a review

INTERNATIONAL NURSING REVIEW, Issue 1 2009
S.L. Johnson rn
Purpose:, This article examines the nursing literature on workplace bullying with the aim of reaching a better understanding of the phenomenon. Background:, Workplace bullying occurs in many occupations and workplaces, including nursing. Methods:, The following databases were used for the literature review: CINAHL, PubMed, Pro Quest and EBSCO host. Only articles in English were used. Articles from outside the nursing literature were also examined to gain a broader understanding of workplace bullying. Findings:, Workplace bullying is more than a simple conflict between two individuals. It is a complex phenomenon that can only be understood through an examination of social, individual and organizational factors. Workplace bullying has been shown to impact the physical and psychological health of victims, as well as their performance at work. Workplace bullying impacts the organization through decreased productivity, increased sick time and employee attrition. Conclusions:, More nurse-specific research is needed in this area. Research needs to be conducted in a systematic and uniform manner so that generalizations across studies can be made. The ultimate goal of this research should be to generate an understanding of this phenomenon so that solutions can be found. [source]

The Mediterranean intercalibration exercise on soft-bottom benthic invertebrates with special emphasis on the Italian situation

MARINE ECOLOGY, Issue 4 2009
Anna Occhipinti Ambrogi
Abstract The intercalibration exercise is an important step in the building process of the surface water ecological quality assessment, which is required by the Water Framework Directive (WFD). Its aim is to apply the water quality classification in a uniform manner to all the Member States belonging to the same eco-region. Cyprus, France, Greece, Italy, Slovenia and Spain participated in the soft-bottom benthic invertebrate subgroup for the Mediterranean coastal region. The methodologies proposed by Member States were applied and tested; the results were compared and harmonized to establish agreed and comparable boundaries for the benthic invertebrate ecological status classes. The national methods used in the intercalibration process were: for Cyprus and Greece, the Bentix Index; for Slovenia, a combination of AZTI Marine Biotic Index (AMBI), richness and diversity with the use of factor and discriminant analysis (Multimetric AMBI); for Spain, a new index, named MEDOCC, which is an adaptation of the AMBI index to the Western Mediterranean area. Italy and France tested different methods, none of which have been officially adopted. Final class boundary values for the different official classification systems were obtained and compared. Besides describing methods and results obtained by the different countries, the Italian situation is examined in more detail. All the above methods have been applied to Italian data, but the results were not conclusive. Major causes for concern are related to insufficient sites and data, to the lack of real non-impacted reference sites, and to the difficulties in validating the ecological status classification in sites not showing a pollution gradient. [source]

An optimal-order error estimate for MMOC and MMOCAA schemes for multidimensional advection-reaction equations

NUMERICAL METHODS FOR PARTIAL DIFFERENTIAL EQUATIONS, Issue 1 2002
Hong Wang
Abstract In this article, we analyze the modified method of characteristics (MMOC) and an improved version of the MMOC, named the modified method of characteristics with adjusted advection (MMOCAA), for multidimensional advection-reaction transport equations in a uniform manner. We derive an optimal-order error estimate for these schemes. Numerical results are presented to verify the theoretical estimates. © 2002 John Wiley & Sons, Inc. Numer Methods Partial Differential Eq 18: 69,84, 2002 [source]

Pediatric diffuse large B-cell lymphoma demonstrates a high proliferation index, frequent c-Myc protein expression, and a high incidence of germinal center subtype: Report of the French,American,British (FAB) international study group,

PEDIATRIC BLOOD & CANCER, Issue 3 2008
Rodney R. Miles MD
Abstract Background Diffuse large B-cell lymphoma (DLBCL) makes up 10,20% of pediatric non-Hodgkin lymphoma, and these patients have a significantly better prognosis than adults with DLBCL. The difference in prognosis may be related to clinical, phenotypic, and/or biological differences between adult and pediatric DLBCL. In adult DLBCL, the germinal center (GC) phenotype is associated with a better prognosis than the activated B-cell (ABC) phenotype. However, a high proliferative index and expression of Bcl2 and c-Myc protein have all been associated with worse outcomes. While multiple studies have addressed the phenotype and expression patterns of adult DLBCL, relatively little is known about these biological variables in pediatric DLBCL. The goal of this study was to investigate the proliferative index, the relative frequencies of the GC and non-GC subtypes, and the expression of Bcl2 and c-Myc protein in a cohort of children with DLBCL treated in a uniform manner. Procedure We performed immunohistochemistry (IHC) for MIB1, CD10, Bcl6, MUM1, Bcl2, and c-Myc on DLBCL tissue from children treated uniformly in the FAB LMB96 trial (SFOP LMB96/CCG5961/UKCCSG/NHL 9600). Results Compared to published adult DLBCL studies, pediatric DLBCL demonstrated moderate to high proliferation rates (83%), increased c-Myc protein expression (84%), decreased Bcl2 protein expression (28%), and an increased frequency of the GC phenotype (75%). Conclusions These findings suggest that there are significant biologic differences between pediatric and adult forms of DLBCL, which may contribute to the superior prognosis seen in the pediatric population relative to adult disease. Pediatr Blood Cancer 2008;51:369,374. © 2008 Wiley-Liss, Inc. [source]