Understanding

Distribution by Scientific Domains

Kinds of Understanding

  • accurate understanding
  • adequate understanding
  • advanced understanding
  • alternative understanding
  • baseline understanding
  • basic understanding
  • belief understanding
  • better understanding
  • broad understanding
  • broader understanding
  • children understanding
  • clear understanding
  • clearer understanding
  • common understanding
  • complete understanding
  • complex understanding
  • comprehensive understanding
  • conceptual understanding
  • contemporary understanding
  • conventional understanding
  • correct understanding
  • critical understanding
  • cultural understanding
  • current understanding
  • deep understanding
  • deeper understanding
  • detailed understanding
  • different understanding
  • ecological understanding
  • economic understanding
  • emerging understanding
  • enhanced understanding
  • evolving understanding
  • false belief understanding
  • full understanding
  • fuller understanding
  • functional understanding
  • fundamental understanding
  • general understanding
  • global understanding
  • good understanding
  • greater understanding
  • growing understanding
  • historical understanding
  • implicit understanding
  • improved understanding
  • improving understanding
  • in-depth understanding
  • incomplete understanding
  • increase understanding
  • increased understanding
  • increasing understanding
  • informed understanding
  • integrate understanding
  • intuitive understanding
  • lay understanding
  • limited understanding
  • little understanding
  • local understanding
  • mechanistic understanding
  • molecular understanding
  • mutual understanding
  • new understanding
  • nuanced understanding
  • only limited understanding
  • own understanding
  • particular understanding
  • patient understanding
  • people understanding
  • personal understanding
  • philosophical understanding
  • physiological understanding
  • poor understanding
  • precise understanding
  • predictive understanding
  • preliminary understanding
  • present understanding
  • process understanding
  • proper understanding
  • public understanding
  • qualitative understanding
  • quantitative understanding
  • realistic understanding
  • recent understanding
  • scientific understanding
  • shared understanding
  • social understanding
  • sociological understanding
  • solid understanding
  • sophisticated understanding
  • sound understanding
  • structural understanding
  • student understanding
  • theoretical understanding
  • thorough understanding
  • traditional understanding
  • unique understanding
  • wider understanding
  • young children understanding

  • Terms modified by Understanding

  • understanding difference
  • understanding mechanism
  • understanding pattern

  • Selected Abstracts


    IMPROVING UNDERSTANDING OF SIBLING EFFECTS ON ADOLESCENT SMOKING: RESPONSE TO THE COMMENTARIES

    ADDICTION, Issue 4 2005
    RICHARD RENDE
    No abstract is available for this article. [source]


    MULTILEVEL FRAMING: AN ALTERNATIVE UNDERSTANDING OF BUDGET CONTROL IN PUBLIC ENTERPRISES

    FINANCIAL ACCOUNTABILITY & MANAGEMENT, Issue 2 2010
    Lars Fallan
    This paper addresses the question as to why there tends to be recurring budget deviations in public sector service organizations. In the public sector, budgets and actuals are loosely coupled, and budgets may serve other institutional functions than control purposes. However, little research has addressed how the framing of budget information may explain the different functions of the budgets as control devices. The paper argues that the valence of budget deviations varies between organizations, and that organizations that have a positively oriented valence towards budget surpluses have a propensity to underspend the budgets. Consequently, organizations that have a positively oriented valence towards budget deficits tend to overspend the budgets. The empirical part analyses the budget situations in the Central Bank of Norway and in a large university hospital in Norway. In the case of the Bank, it was found that underspending of budgets was framed as performance measures indicating high organizational efficiency. The Hospital, on the other hand, showed a different picture as budget deficits were the situation during all years studied. One main finding was the key actors' roles as translators of the society's expectations as to the fulfilling of the organizations' missions. These translators function as mediators between the institutional context and pressures, the organizations' goals and the internal budget processes. The conventional wisdom that the budget also acts as a means of communication and as symbols and ritual acts that reflect the institutional contingencies of the organizations, is further developed by describing how organizations' goals valence the role of budgets. [source]


    THE COMMONPLACES OF "REVISION" AND THEIR IMPLICATIONS FOR HISTORIOGRAPHICAL UNDERSTANDING

    HISTORY AND THEORY, Issue 4 2007
    JONATHAN GORMAN
    ABSTRACT Recognizing the contingent entanglement between historiography's social and political roles and the conception of the discipline as purely factual, this essay provides a detailed analysis of "revision" and its connection to "revisionism." This analysis uses a philosophical approach that begins with the commonplaces of our understanding as expressed in dictionaries, which are compared and contrasted to display relevant confusions. The essay then turns to examining the questions posed by History and Theory's Call for Papers announcing its Theme Issue on Revision in History, and, where philosophically relevant, answers them. The issue of paradigm change proved to be quite significant and required particular attention. A "paradigm" is analyzed in terms of Quine's "web of belief," and that web is itself explained as an ongoing process of revision, in analogy with Rawls's concept of pure procedural justice. Adopting this approach helps clarify the entanglement between politics and historiographical revision. [source]


    THE RELATION BETWEEN TRINITY AND ECCLESIOLOGY AS AN ECUMENICAL CHALLENGE AND ITS CONSEQUENCES FOR THE UNDERSTANDING OF MISSION

    INTERNATIONAL REVIEW OF MISSION, Issue 359 2001
    Matthias Haudel
    [source]


    HERMENEUTICS: PHILOSOPHICAL UNDERSTANDING AND BASIC ORIENTATIONS

    JOURNAL OF CHINESE PHILOSOPHY, Issue 2006
    LAUREN F. PFISTER
    [source]


    PUBLIC UNDERSTANDING OF FOOD RISK ISSUES AND FOOD RISK MESSAGES ON THE ISLAND OF IRELAND: THE VIEWS OF FOOD SAFETY EXPERTS

    JOURNAL OF FOOD SAFETY, Issue 4 2005
    MARTINE DE BOER
    ABSTRACT Food safety experts have a key role in constructing food risk messages and thus their perceptions will influence how food risk issues are communicated to the public. This research examined the perceptions of food safety experts regarding public understanding of food risk issues and food risk messages on the island of Ireland. It also looked into expert views of the barriers to effective food risk communication and how to improve food risk messages. One hundred and forty-three experts, working in areas related to food safety, completed an online questionnaire. Questionnaire and statement design was guided by the results of four in-depth interviews with food safety experts. The findings indicate that most experts surveyed have little confidence in the public's understanding of food risk issues, their assessment of food risks, their ability to deal with scientific information and their food safety practices. Experts are of the view that the public under-assesses the risk associated with some microbiological hazards and over-assesses the risk associated with other hazards such as genetically modified organisms (GMOs) and bovine spongiform encephalopathy. The opinion of experts with regard to GMOs is not supported by previous consumer research. Experts noted that the level of education and age were important determinants for the level of understanding of food risk issues and messages. Experts were of the view that early intervention via school curricula was the best method to improve public understanding of food risk messages in the long term. Furthermore, experts are of the view that the media have the ability to improve awareness and knowledge about food risk issues but believe that the media tend to communicate information that is misleading. The majority of experts also believe that they should communicate uncertainty but are not confident that the public is able to cope with this uncertainty. Many of the experts also indicated a desire for training on how to interact with the media. The results may be used by those experts who are involved in the construction of food risk messages to improve the design and communication of food risk messages. [source]


    UNDERSTANDING AND TEACHING THE REVISED UNIFORM PARTNERSHIP ACT

    JOURNAL OF LEGAL STUDIES EDUCATION, Issue 1 2000
    Daniel M. Warner
    [source]


    A CONCEPTUAL UNDERSTANDING OF REQUIREMENTS FOR THEORY-BUILDING RESEARCH: GUIDELINES FOR SCIENTIFIC THEORY BUILDING,

    JOURNAL OF SUPPLY CHAIN MANAGEMENT, Issue 3 2008
    JOHN G. WACKER
    Business academics have focused their attention on empirical investigation of programs' effect on organizational competitive performance. These studies primarily emphasize theory building. With the many definitions of theory, academics are not certain whether their research papers meet the specific requirements for theory development required by the academic field of the philosophy of science. Certainly, supply chain academics generally believe that their academic articles fulfill the requirements of theory building. Although many of these articles do have elements of theory, more focus is needed on the specific requirements of theory to assure that academic research is "good" theory building. The primary purpose of this research paper is to logically develop a set of guidelines to assist empirical researchers to assure that their studies fulfill the requirements of good theory based upon traditional scientific theory building. By fulfilling the requirements of good theory, researchers will develop studies that will have a lasting impact on their academic field. To achieve a lasting impact on an academic field, it is necessary to follow a logical plan. This article provides a plan for logical guidelines for developing an understanding of how and why "good" theory building is achieved. This article logically develops a formal conceptual definition of theory along with its related properties to understand these guidelines. Next, it analyzes the requirements of theory, "good" theory, and their properties. These guidelines are included in the existing philosophy of science publications. However, this article consolidates these sources and logically explains why these guidelines are needed. In the conclusion, the guidelines are summarized to serve as a summary checklist for supply chain researchers to use for ensuring their articles will be recognized as a contribution to the academic field. So in that sense, this article does not develop a revolutionary new insight into theory-building empirical articles, but rather integrates diverse traditional philosophy of science requirements into a much simpler set of guidelines. Through logical development of these guidelines, researchers will understand the structure of theory and how to ensure their studies can be modified to have a lasting impact on the field of supply chain management. [source]


    THE ECONOMIC VALUE OF ENVIRONMENTAL RESEARCH IN UNDERSTANDING THE RELATIVE CONTRIBUTIONS OF SOURCES OF NUTRIENTS TO COASTAL WATERS

    NATURAL RESOURCE MODELING, Issue 2 2006
    DI JIN
    ABSTRACT. We model the value of environmental research in the presence of uncertainty about thesources of environmental pollutants and natural processes affecting the level of pollution. The model may be used to estimate the value of environmental research directed at resolving the uncertainty. We illustrate the model using a numerical simulation of a hypothetical case involving nutrient pollution of coastal waters. We show that the ex ante value of research is positively related to the level of uncertainty. There is a diminishing return with respect to the level of research investment. We find that research is more valuable ex post if it leads to unexpected findings. [source]


    THE DOUBLE-AXE: A CONTEXTUAL APPROACH TO THE UNDERSTANDING OF A CRETAN SYMBOL IN THE NEOPALATIAL PERIOD

    OXFORD JOURNAL OF ARCHAEOLOGY, Issue 1 2010
    MATTHEW HAYSOM
    Summary The Double-Axe has always been considered as one of the most important religious symbols in Minoan Crete. This paper reassesses the significance of the Double-Axe and puts forward a new interpretation for it. It recognizes the great potential for change in symbolic meanings during the Bronze Age and seeks to understand the Double-Axe in as narrow a period as is realistically possible by filtering out evidence from other periods. Central to the argument is the principle that the meaning of symbols is contextually dependent. It builds, therefore, a new interpretation of the Double-Axe on the basis of as wide a range of contextual associations as possible, both within iconographic sources and in the wider material record. From these contextual associations, it suggests that in the Neopalatial period the Double-Axe was a symbol primarily associated with a social group which exercised power in the economic, military and religious realms and that it became a solely religious symbol only later. [source]


    TOWARDS AN UNDERSTANDING OF INTEGRITY TEST SIMILARITIES AND DIFFERENCES: AN ITEM-LEVEL ANALYSIS OF SEVEN TESTS

    PERSONNEL PSYCHOLOGY, Issue 4 2003
    JAMES E. WANEK
    A judgmental sort of 798 items from 7 paper-and-pencil integrity tests produced 23 thematic composites. Patterns of correlations between these composites and the 7 integrity measures and 2 Big Five measures shed light on similarities and differences between different integrity tests. Principal components analysis of 23 composites indicated 4 principal components that further illuminate the content domain of integrity tests. The relationships between 4 integrity principal components and integrity test scores as well as measures of the Big Five dimensions of personality are reported. The findings suggest that integrity tests can differ in their emphasis on various thematic composites, and, yet, be very similar in terms of their standing on the 4 integrity principal components. Different integrity tests can be quite different in terms of surface content, and, yet, assess the same underlying constructs. [source]


    TOWARD AN UNDERSTANDING OF EMPLOYMENT DISCRIMINATION CLAIMING: AN INTEGRATION OF ORGANIZATIONAL JUSTICE AND SOCIAL INFORMATION PROCESSING THEORIES

    PERSONNEL PSYCHOLOGY, Issue 2 2001
    BARRY M. GOLDMAN
    This research examines predictors of actual discrimination claiming among terminated workers by investigating a number of variables suggested by organizational justice and social information processing theories. This study investigated initial decisions to claim in a sample of 439 terminated workers who were surveyed at several unemployment offices. Logistic regression was used to examine how the decision to claim for discrimination was affected by procedural and distributive justice, social guidance, minority status, gender, age, tenure, and education. All of the variables except education and gender were found to be significant. Thus, the results support variables from each of the theories. Social guidance was found to have a major influence on discrimination-claiming. A counter-intuitive finding for minority status was found such that Whites were more likely to claim than minorities. Theoretical and practical implications are discussed. [source]


    ANTHROPOLOGICAL APPROACHES TO THE GLOBAL FOOD CRISIS: UNDERSTANDING AND ADDRESSING THE "SILENT TSUNAMI"

    ANNALS OF ANTHROPOLOGICAL PRACTICE, Issue 1 2009
    David Himmelgreen
    The food riots and demonstrations that occurred in more than 50 countries in 2008 signaled the oncoming global economic recession. Skyrocketing food and fuel prices spurred on violence in poorer countries where there is no social safety net and in places impacted by food insecurity and malnutrition. Today, while the prices for some food staples have retracted a little, the deepening economic recession poses a threat in wealthier nations including the United States and members of the European Union. For example, the shuttering fall in the U.S. stock market in October 2008 resulted in the loss of billions of dollars not only to individual investors but also to states and local municipalities. In this environment, there is a potentially grave threat to the social safety net in the United States including food assistance programs. The World Food Program (WFP) has cited the increase in world food prices as the biggest challenge in its 45-year history, calling the impact a "silent tsunami" that threatened to plunge millions into hunger. In this volume, practicing and applied anthropologists examine the current global food crisis in a variety of settings including Belize, Cuba, the Dominican Republic, Ethiopia, Lesotho, Mozambique, Tanzania, and the United States. Further, they use a variety of theoretical orientations and methodological approaches to understand the chronic nature of food insecurity and the ways in which global food policies and economic restructuring have resulted in increasing food inequities across the globe. Throughout this volume, the authors make suggestions for combating the global food crisis through the application of anthropological principles and practices. [source]


    RISING FOOD PRICES, SOCIAL MOBILIZATIONS, AND VIOLENCE: CONCEPTUAL ISSUES IN UNDERSTANDING AND RESPONDING TO THE CONNECTIONS LINKING HUNGER AND CONFLICT

    ANNALS OF ANTHROPOLOGICAL PRACTICE, Issue 1 2009
    Ellen Messer
    In 2008, the world confronted food-insecurity situations that provoked political demonstrations in more than 50 countries. The alleged sources were production failures and spiking food prices because of bad weather and flawed food and development policies. But additional contributors were the legacies of food wars, armed conflicts in which one or both sides use food (or hunger) as a weapon and in which hunger persists as a consequence of conflict and its attendant social-economic disruptions. This article argues that UN and NGO international and national agencies responding to food insecurity challenges in particular places must consider food-and-conflict scenarios, and adopt conflict-concerned strategies, which are sensitive to the ways in which past foodwars have stymied increases in agricultural production, marketing, and livelihood diversification. Policy makers should also be attentive to political-geographic-ethnic-religious (PGER) divisions that can skew government distributions and access to aid and potentiate additional conflict. [source]


    ANTHROPOLOGICAL APPROACHES FOR UNDERSTANDING THE COMPLEXITIES OF THE GLOBAL FOOD CRISIS

    ANNALS OF ANTHROPOLOGICAL PRACTICE, Issue 1 2009
    Sunil K. Khanna
    The current global food crisis can be, in part, described as an outcome of not only historical patterns of income inequalities and long-standing food trade policies biased in favor of wealthier nations but also in terms of significant reductions in food aid and other safety-net programs for people living in poor nations. Despite the serious nature of the problem of food insecurity, only a limited amount of reliable descriptive research, especially at the community level, has explored the causes and consequences of the current food crisis. Anthropology offers a unique set of methodological and theoretical approaches that can be useful for designing, implementing, and evaluating programs and policies aimed at alleviating poverty and reducing food insecurity. Anthropologically informed research can provide a dynamic understanding of food insecurity in terms of its causes and consequences and its local, regional, and global underpinnings. This information can be helpful in incorporating a community-level understanding of the "local" determinants of food insecurity for developing effective and sustainable food policy and intervention programs. [source]


    INCOMPLETE UNDERSTANDING OF INCOMPLETE DESCENT

    ANZ JOURNAL OF SURGERY, Issue 11 2008
    FRACS, MS (Melb), Spencer W. Beasley MBChB (Otago)
    No abstract is available for this article. [source]


    CHEMICAL CHARACTERIZATION OF TIN-LEAD GLAZED POTTERY FROM THE IBERIAN PENINSULA AND THE CANARY ISLANDS: INITIAL STEPS TOWARD A BETTER UNDERSTANDING OF SPANISH COLONIAL POTTERY IN THE AMERICAS,

    ARCHAEOMETRY, Issue 4 2009
    J. G. IÑAÑEZ
    Majolica pottery was the most characteristic tableware produced in Europe during the Medieval and Renaissance periods. Because of the prestige and importance attributed to this ware, Spanish majolica was imported in vast quantities into the Americas during the Spanish Colonial period. A study of Spanish majolica was conducted on a set of 186 samples from the 10 primary majolica production centres on the Iberian Peninsula and 22 sherds from two early colonial archaeological sites on the Canary Islands. The samples were analysed by neutron activation analysis (NAA), and the resulting data were interpreted using an array of multivariate statistical approaches. Our results show a clear discrimination between different production centres, allowing a reliable provenance attribution of the sherds from the Canary Islands. [source]


    Planetary gear set and automatic transmission simulation for machine design courses,

    COMPUTER APPLICATIONS IN ENGINEERING EDUCATION, Issue 3 2003
    Scott T. Dennis
    Abstract Due to their unique ability to provide a variety of gear ratios in a very compact space, planetary gear systems are seen in many applications from small powered screw drivers to automobile automatic transmissions. The versatile planetary gear device is often studied as part of an undergraduate mechanical engineering program. Textbook presentations typically illustrate how the different planetary gear components are connected. Understanding of the operation of the planetary gear set can be enhanced using actual hardware or simulations that show how the components move relative to each other. The Department of Engineering Mechanics at the United States Air Force Academy has developed a computer simulation of the planetary gear set and the Chrysler 42LE automatic transmission. Called "PG-Sim," the dynamic simulations complement a static textbook presentation. PG-Sim is used in several of our courses and assessment data clearly indicates students' appreciation of its visual and interactive features. In this paper, we present an overview of PG-Sim and then describe how the simulation courseware facilitates understanding of the planetary gear system. © 2003 Wiley Periodicals, Inc. Comput Appl Eng Educ 11: 144,155, 2003; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.10045 [source]


    Instant Volumetric Understanding with Order-Independent Volume Rendering

    COMPUTER GRAPHICS FORUM, Issue 3 2004
    Benjamin Mora
    Rapid, visual understanding of volumetric datasets is a crucial outcome of a good volume rendering application, but few current volume rendering systems deliver this result. Our goal is to reduce the volumetric surfing that is required to understand volumetric features by conveying more information in fewer images. In order to achieve this goal, and in contrast with most current methods which still use optical models and alpha blending, our approach reintroduces the order-independent contribution of every sample along the ray in order to have an equiprobable visualization of all the volume samples. Therefore, we demonstrate how order independent sampling can be suitable for fast volume understanding, show useful extensions to MIP and X-ray like renderings, and, finally, point out the special advantage of using stereo visualization in these models to circumvent the lack of depth cues. Categories and Subject Descriptors: I.3.3 [Computer Graphics]: Picture/Image, Generation, I.3.7 [Computer Graphics]: Three-Dimensional graphics and realism. [source]


    How accurately can parameters from exponential models be estimated?

    CONCEPTS IN MAGNETIC RESONANCE, Issue 2 2005
    A Bayesian view
    Abstract Estimating the amplitudes and decay rate constants of exponentially decaying signals is an important problem in NMR. Understanding how the uncertainty in the parameter estimates depends on the data acquisition parameters and on the "true" but unknown values of the exponential signal parameters is an important step in designing experiments and determining the amount and quality of the data that must be gathered to make good parameter estimates. In this article, Bayesian probability theory is applied to this problem. Explicit relationships between the data acquisition parameters and the "true" but unknown exponential signal parameters are derived for the cases of data containing one and two exponential signal components. Because uniform prior probabilities are purposely employed, the results are broadly applicable to experimental parameter estimation. © 2005 Wiley Periodicals, Inc. Concepts Magn Reson Part A 27A: 73,83, 2005 [source]


    Wildfire Policy and Public Lands: Integrating Scientific Understanding with Social Concerns across Landscapes

    CONSERVATION BIOLOGY, Issue 4 2004
    MICHAEL P. DOMBECK
    administración de bosques; fuego no controlado; política; Servicio Forestal Estados Unidos; tierras públicas Abstract:,Efforts to suppress wildfires have become increasingly problematic in recent years as costs have risen, threats to firefighter safety have escalated, and detrimental impacts to ecosystems have multiplied. Wildfires that escape initial suppression often expand into large, high-intensity summer blazes. Lost is the legacy of smaller fires that likely burned outside extreme weather and fuel conditions and resulted in less severe impacts. Despite the recognized need for modifications to existing policies and practices, resource agencies have been slow to respond. The spread of exotic species, climate change, and increasing human development in wildlands further complicates the issue. New policies are needed that integrate social and ecological needs across administrative boundaries and broad landscapes. These policies should promote a continuum of treatments with active management and reduction of fuel hazard in wildland-urban interface zones and reintroduction of fire in wildlands. Management goals should focus on restoration of the long-term ecological health of the land. Projects that reduce fuel loads but compromise the integrity of soil, water supplies, or watersheds will do more harm than good in the long run. Despite significant ecological concerns, learning to live with fire remains primarily a social issue that will require greater political leadership, agency innovation, public involvement, and community responsibility. Resumen:,En años recientes, los esfuerzos para suprimir los fuegos no controlados se han vuelto cada vez más problemáticos por el incremento de costos, el aumento de las amenazas a la seguridad de bomberos y se la multiplicio, de los impactos perjudiciales a los ecosistemas. Los incendios que escapan la supresión inicial a menudo se expanden a grandes conflagraciones estivales de alta intensidad. Se ha perdido el legado de fuegos menores que probablemente se llevaban a cabo en condiciones climáticas y de combustible extremas que tenían impactos menos severos. A pesar del reconocimiento de la necesidad de modificaciones a las políticas y prácticas actuales, las agencias han respondido lentamente. La expansión de especies exóticas, el cambio climático y el incremento del desarrollo humano en áreas silvestres complican el problema aún más. Se requieren políticas nuevas que integren necesidades sociales y ecológicas más allá de límites administrativos y en paisajes amplios. Estas políticas deben promover un continuo de tratamientos con gestión activa y reducción de riesgo de combustión en la interfase área silvestre-urbana y la reintroducción de fuego en áreas silvestres. Las metas de la gestión deben enfocar en la restauración de la salud ecológica a largo plazo. Los proyectos que reducen la carga de combustible pero que comprometen la integridad del suelo, las reservas de agua o cuencas hidrológicas no serán de mucha utilidad en el largo plazo. A pesar de preocupaciones ecológicas significativas, aprender a vivir con fuego seguirá siendo un aspecto social que requerirá de mayor liderazgo político, innovación de agencias, participación del público y responsabilidad comunitaria. [source]


    David Martin, Christian Language and its Mutations: Essays in Sociological Understanding

    CONVERSATIONS IN RELIGION & THEOLOGY, Issue 1 2004
    Article first published online: 4 MAY 200
    David Martin, Christian Language and its Mutations: Essays in Sociological Understanding Reviewed by Ian Markham [source]


    AMPK-dependent hormonal regulation of whole-body energy metabolism

    ACTA PHYSIOLOGICA, Issue 1 2009
    N. L. Dzamko
    Abstract AMP-dependent protein kinase (AMPK) is an evolutionarily conserved serine/threonine protein kinase central to the regulation of energy balance at both the cellular and whole-body levels. In its classical role as an intracellular metabolic stress-sensing kinase, AMPK switches on fatty acid oxidation and glucose uptake in muscle, while switching off hepatic gluconeogenesis. AMPK also has a broader role in metabolism through the control of appetite. Regulation of AMPK activity at the whole-body level is coordinated by a growing number of hormones and cytokines secreted from adipose tissue, skeletal muscle, pancreas and the gut including leptin, adiponectin, insulin, interluekin-6, resistin, TNF-, and ghrelin. Understanding how these secreted signalling proteins regulate AMPK activity to control fatty acid oxidation, glucose uptake, gluconeogenesis and appetite may yield therapeutic treatments for metabolic disorders such as diabetes, insulin resistance and obesity. [source]


    Improving Students' Understanding of International Trade

    DECISION SCIENCES JOURNAL OF INNOVATIVE EDUCATION, Issue 1 2009
    John F. Repede
    First page of article [source]


    Full Scope of Effect of Facial Lipoatrophy: A Framework of Disease Understanding

    DERMATOLOGIC SURGERY, Issue 8 2006
    BENJAMIN ASCHER MD
    BACKGROUND Facial lipoatrophy has been observed to occur in a variety of patient populations, with inherited or acquired disease, or even in aging patients as a natural progression of tissue change over time. There is currently no framework from which physicians of all medical specialties can communally discuss the manifestations, diagnoses, and management of facial lipoatrophy. OBJECTIVE The aim of this assembly was to derive a definition of facial lipoatrophy capable of being applied to all patient populations and develop an accompanying grading system. RESULTS The final consensus of the Facial Lipoatrophy Panel encompasses both aging and disease states: "Loss of facial fat due to aging, trauma or disease, manifested by flattening or indentation of normally convex contours." The proposed grading scale includes five gradations (Grades 1,5; 5 being the most severe), and the face is assessed according to three criteria: contour, bony prominence, and visibility of musculature. CONCLUSION Categorizing the presentation of facial lipoatrophy is subjective and qualitative, and will need to be validated with objective measures. Furthermore, during the assembly, several topics were exposed that warrant further research, including the physiology of volume loss, age and lipoatrophy, and human immunodeficiency virus and lipoatrophy. [source]


    Body Dysmorphic Disorder and the Liposuction Patient

    DERMATOLOGIC SURGERY, Issue 5 2005
    Dee Anna Glaser MD
    background. Body dysmorphic disorder (BDD) is an under-recognized disorder that affects a sizeable number of patients who seek cosmetic enhancement, in particular liposuction. Understanding and recognizing BDD can positively impact the care delivered to patients. objective. To familiarize physicians with the presenting signs of BDD and present strategies for caring for BDD patients in a liposuction and/or cosmetic surgery practice. methods. Review of currently available literature and diagnostic criteria. results. BDD affects approximately 1% of patients in the United States, but as many as 7 to 15% of patients seeking cosmetic surgery. Patients with BDD will usually demonstrate an obsession with the area they seek treatment of. In addition, patients with BDD present a unique challenge to the liposuction surgeon. conclusions. Physicians who care for patients seeking liposuction or other cosmetic procedures should learn to recognize those who have BDD. Proper recognition and counseling of BDD patients can have a significant positive impact on not only their care but also on the patient-physician relationship. Failure to recognize BDD can, and often does, lead to patient dissatisfaction, as well as difficult future interactions with the BDD patient. [source]


    Challenging Orthodoxies: Understanding Poverty in Pastoral Areas of East Africa

    DEVELOPMENT AND CHANGE, Issue 4 2008
    Peter D. Little
    ABSTRACT Understanding and alleviating poverty in Africa continues to receive considerable attention from a range of diverse actors, including politicians, international celebrities, academics, activists and practitioners. Despite the onslaught of interest, there is surprisingly little agreement on what constitutes poverty in rural Africa, how it should be assessed, and what should be done to alleviate it. Based on data from an interdisciplinary study of pastoralism in northern Kenya, this article examines issues of poverty among one of the continent's most vulnerable groups, pastoralists, and challenges the application of such orthodox proxies as incomes/expenditures, geographic remoteness, and market integration. It argues that current poverty debates ,homogenize' the concept of ,pastoralist' by failing to acknowledge the diverse livelihoods and wealth differentiation that fall under the term. The article concludes that what is not needed is another development label (stereotype) that equates pastoralism with poverty, thereby empowering outside interests to transform rather than strengthen pastoral livelihoods. [source]


    The molecular receptive range of an olfactory receptor in vivo (Drosophila melanogaster Or22a)

    DEVELOPMENTAL NEUROBIOLOGY, Issue 14 2006
    Daniela Pelz
    Abstract Understanding how odors are coded within an olfactory system requires knowledge about its input. This is constituted by the molecular receptive ranges (MRR) of olfactory sensory neurons that converge in the glomeruli of the olfactory bulb (vertebrates) or the antennal lobe (AL, insects). Aiming at a comprehensive characterization of MRRs in Drosophila melanogaster we measured odor-evoked calcium responses in olfactory sensory neurons that express the olfactory receptor Or22a. We used an automated stimulus application system to screen [Ca2+] responses to 104 odors both in the antenna (sensory transduction) and in the AL (neuronal transmission). At 10,2 (vol/vol) dilution, 39 odors elicited at least a half-maximal response. For these odorants we established dose-response relationships over their entire dynamic range. We tested 15 additional chemicals that are structurally related to the most efficient odors. Ethyl hexanoate and methyl hexanoate were the best stimuli, eliciting consistent responses at dilutions as low as 10,9. Two substances led to calcium decrease, suggesting that Or22a might be constitutively active, and that these substances might act as inverse agonists, reminiscent of G-protein coupled receptors. There was no difference between the antennal and the AL MRR. Furthermore we show that Or22a has a broad yet selective MRR, and must be functionally described both as a specialist and a generalist. Both these descriptions are ecologically relevant. Given that adult Drosophila use approximately 43 ORs, a complete description of all MRRs appears now in reach. © 2006 Wiley Periodicals, Inc. J Neurobiol, 2006 [source]


    Understanding of speaker certainty and false-belief reasoning: a comparison of Japanese and German preschoolers

    DEVELOPMENTAL SCIENCE, Issue 4 2009
    Tomoko Matsui
    It has been repeatedly shown that when asked to identify a protagonist's false belief on the basis of his false statement, English-speaking 3-year-olds dismiss the statement and fail to attribute to him a false belief. In the present studies, we tested 3-year-old Japanese children in a similar task, using false statements accompanied by grammaticalized particles of speaker (un)certainty, as in everyday Japanese utterances. The Japanese children were directly compared with same-aged German children, whose native language does not have grammaticalized epistemic concepts. Japanese children profited from the explicit statement of the protagonist's false belief when it was marked with the attitude of certainty in a way that German children did not , presumably because Japanese but not German children must process such marking routinely in their daily discourse. These results are discussed in the broader context of linguistic and theory of mind development. [source]


    Understanding and beliefs of diabetes in the UK Bangladeshi population

    DIABETIC MEDICINE, Issue 6 2009
    S. M. Choudhury
    Abstract Aims, To examine the understanding and beliefs of people with diabetes from the Bangladeshi community living in the UK. Methods, Structured interviews were carried out with 14 people invited to a peer educational programme. All interviews were on a one-to-one basis and were in Sylheti or in English. Interviews were transcribed and analysed by two independent researchers. Results, The majority of participants did not know what caused diabetes. Knowledge of the management of diabetes was linked to controlling sugar intake and a number of participants reported eating bitter foods such as bitter gourd to control their diabetes. There was little access to information as many participants did not speak English and did not have a Bengali-speaking doctor. The majority of participants felt that education classes should teach them what the doctor thought was important and that these classes would best be advertised by word of mouth. Therefore, participants were quite passive about their own self management and relied very strongly on the doctor's views and recommendations. Conclusions, Findings from this study can be used to help health professionals working with Bangladeshi people. There is a need for improved information for Bangladeshi people and much of this information might need to come from health professionals. In addition, there is a need for increased awareness by health professionals of practices used by Bangladeshi people, such as eating bitter gourd (which may enhance the effects of rosiglitazone), and the influence these practices could have on the individual's diabetes management. [source]