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UK Samples (uk + sample)
Selected AbstractsParents of Adults with Intellectual Disabilities: Quality of Life and Experiences of CaringJOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, Issue 2 2000Sarah Walden This study examined a UK sample of parents caring for their adult offspring with intellectual disabilities, and the factors contributing to their quality of life and experiences of caregiving. Structured interviews were conducted with 62 parents of adults with intellectual disabilities. On several indices of quality of life, parents did not seem to be functioning as well as caregiving parents in the US, or as well as adults in the general US population. The offspring's level of challenging behaviour and physical dependency and the parent's satisfaction with informal support were associated with parental quality of life. The salience that parents placed on their post-parental life style was also associated with quality of life, with ,captive' parents faring more poorly than ,captivated' parents. [source] Modelling Transparency in Disclosure: The Case of Foreign Exchange Risk ManagementJOURNAL OF BUSINESS FINANCE & ACCOUNTING, Issue 5-6 2007Andrew Marshall Abstract:, When managers choose not to disclose all the relevant information in their possession in their financial statements, there is an information gap between the managers and users and consequently a lack of transparency. We model the degree of transparency observed when disclosures of foreign exchange (FX) risk management in financial statements are compared to managerial information on FX risk management policy, as evidenced in questionnaire responses. In this comparative study of US and UK firms we find incomplete disclosure in both samples but with differing aspects. In the US case, the information gap is lower where the information has higher relevance or firms with higher financial risk (greater leverage) are signalling the extent of risk, but the gap is greater where firms are in competitive product markets. For the UK sample, the information gap is significantly lower where firms have higher financial risk or higher liquidity but the gap is greater where the shares are more closely held. We conclude that modelling and explaining this aspect of incomplete accounting disclosure in an international setting must be sufficiently flexible to accommodate national differences in managerial behaviour. [source] Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samplesDIABETIC MEDICINE, Issue 12 2005E. Zeggini Abstract Aims The Pro12Ala polymorphism in the PPARG gene alters amino acid sequence and has shown consistent association with susceptibility to Type 2 diabetes in several populations. The present study makes use of large, well-characterized case-control resources to enhance understanding of this susceptibility effect by examining related traits, such as body mass index (BMI), waist,hip ratio and age at diagnosis. Methods The Pro12Ala variant was genotyped in two UK case samples, ascertained for positive family history and/or early onset of Type 2 diabetes (combined n = 971); and in 1257 ethnically matched control subjects. Results There were significant associations of the Pro12Ala single nucleotide polymorphism (SNP) genotypes with diabetes in both case-control comparisons (P = 0.025 and P = 0.039). Comparing individuals homozygous for the Pro allele, with those carrying an Ala allele, the combined odds ratio for diabetes was 1.40 (95% CIs, 1.12,1.76, P = 0.0031). There was no association between the variant and either waist,hip ratio or age at diagnosis. Proline homozygosity was associated with increased BMI in one patient group (P = 0.013) and decreased BMI in the other (P = 0.038). Conclusions This study confirms that variation within PPARG influences susceptibility to Type 2 diabetes in UK samples. However, the relationship between PPARG variation and BMI is more complex, and studies in much larger sample sets will be required to more precisely characterize the effect of this variant on adiposity. [source] Pollen beetle in the UK; the start of a resistance problem?EPPO BULLETIN, Issue 1 2008D. M. Richardson In 2003, the first report of poor control of pollen beetle Meligethes aeneus at a site in South East England in the UK was investigated but resistance to pyrethroid insecticides was not confirmed in subsequent laboratory testing. Bioassays of 26 UK samples of M. aeneus collected in 2004 with the pyrethroid lambda-cyhalothrin showed little or no divergence from the response expected of a fully susceptible strain. In 2006 samples of pollen beetle from the UK were sent to Germany, and again these were shown to be fully susceptible. In 2007 using test kits supplied by Udo Heimbach, BBA, 19 samples of pollen beetle were tested, again from across the UK. Results indicated that a small number of individuals were fully resistant, surviving the highest dose of lambda-cyhalothrin tested (0.375 microg/L) after 5-h exposure at 4 sites, and after 24-h exposure at 2 of these sites. [source] New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UKPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 2 2002Kevin Gorman Abstract A recent survey of insecticide resistance in two of the most problematic pests in UK glasshouses revealed some new developments. At least some individuals in all UK samples of Trialeurodes vaporariorum that were tested resisted the insect growth regulator (IGR) buprofezin. The most strongly resistant strains were unaffected by the field application rate of this compound, and even samples from populations that had never been exposed to buprofezin contained individuals that survived the highest concentration applied (10,000,mg,litre,1). The field rate of buprofezin was shown to select for resistance through vapour action alone. The benzophenylurea teflubenzuron, an unrelated IGR, was cross-resisted by buprofezin-resistant individuals. There was no evidence of resistance to imidacloprid, but all T vaporariorum strains tested, regardless of origin, exhibited a high innate tolerance to nicotine, when compared with another whitefly species, Bemisia tabaci. Marked resistance to fenbutatin oxide and tebufenpyrad was found in single glasshouse populations of Tetranychus urticae, but these compounds and abamectin appeared to remain highly effective against all other strains collected. © 2001 Society of Chemical Industry [source] | ||||||||||