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Selected AbstractsPIRACY: Patrols Are Not EnoughAFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 4 2009Article first published online: 4 JUN 200 No abstract is available for this article. [source] Hysterical Traits Are Not from the Uterus but from the Testis: A Study in Men with Sexual DysfunctionTHE JOURNAL OF SEXUAL MEDICINE, Issue 8 2009Elisa Bandini MD ABSTRACT Introduction., The relationship between testosterone (T) and psychopathology in subjects with sexual dysfunction has not been completely clarified. Aim., To evaluate the association between T levels and different psychopathological symptoms and traits in men seeking treatment for sexual dysfunction. Methods., A consecutive series of 2,042 heterosexual male patients (mean age 51.8 ± 13) consulting an outpatient clinic for sexual dysfunction was retrospectively studied. Main Outcome Measures., Several hormonal, biochemical, and instrumental parameters were investigated, including testis volume (Prader orchidometr) and penile blood flow (penile Doppler ultrasound). Patients were interviewed, prior to the beginning of any treatment, with the previously validated Structured Interview on Erectile Dysfunction (SIEDY), and ANDROTEST (a structured interview for the screening of hypogonadism in patients with sexual dysfunction). They also completed the Middlesex Hospital Questionnaire (MHQ) a brief self-reported questionnaire for the screening of the symptoms of mental disorders in nonpsychiatric setting. Results., T levels showed a negative correlation with depressive and anxiety (somatized and phobic) symptoms. Conversely, histrionic/hysterical traits were strongly and positively associated with elevated T. Men with histrionic/hysterical traits had higher androgenization, as suggested by both higher total and free T, higher testis volume and a lower ANDROTEST score. They were also characterized by better self-reported sexual functioning and penile blood flow. Accordingly, when SIEDY scales were considered, SIEDY scale 2 (relational domain) was significantly lower in subjects with histrionic/hysterical traits further indicating a more satisfying sexual relationship. Conclusions., In men consulting for sexual dysfunction, histrionic/hysterical personality is associated with higher androgenization and better sexual functioning. Hysteria, previously considered as a typically feminine psychopathological trait (the uterine theory), should now be considered as an index of better masculine sexual well-being. Bandini E, Corona G, Ricca V, Fisher AD, Lotti F, Sforza A, Faravelli C, Forti G, Mannucci E, and Maggi M. Hysterical traits are not from the uterus but from the testis: A study in men with sexual dysfunction. J Sex Med 2009;6:2321,2331. [source] Cage Isomers of N14 and N16: Nitrogen Molecules that Are Not a Multipe of SixCHEMINFORM, Issue 7 2005Douglas L. Strout Abstract For Abstract see ChemInform Abstract in Full Text. [source] Serum S-100 Protein Is Not a Suitable Seizure Marker in Temporal Lobe EpilepsyEPILEPSIA, Issue 10 2002Fritz Leutmezer Summary: ,Purpose: S-100 protein is a sensitive marker of various brain diseases; however, its role in epilepsy is controversially discussed in the literature. We therefore studied the temporal profile of serial concentrations of S-100 protein in serum after secondarily generalized tonic,clonic seizures during video-EEG monitoring. Methods: Ten patients with mesial temporal lobe epilepsy were prospectively studied. Serum S-100 protein was measured after a seizure-free period of ,24 h (baseline) and 30 min, 3, 6, 12, and 24 h after a secondarily generalized tonic,clonic seizure of temporal lobe origin in nine and a convulsive status epilepticus in one patient. Results: All S-100 levels were within the normal range, except for those of one patient at baseline. Mean values were 0.045 ,g/L (range, 0.003,0.13 ,g/L) at baseline, 0.038 ,g/L (range, 0.003,0.09 ,g/L) at 30 min, 0.036 ,g/L (range, 0.003,0.08 ,g/L) at 3 h, 0.034 ,g/L (range, 0.003,0.07 ,g/L) at 6 h, 0.034 ,g/L (range, 0.003,0.08 ,g/L) at 12 h, and 0.035 ,g/L (range, 0.003,0.09 ,g/L) at 24 h after seizure offset. There were no significant differences between mean concentrations at any interval postictally. Conclusions: We could not detect any significant alterations in serum S-100 protein concentration either after a single secondarily generalized tonic,clonic seizure or after convulsive status epilepticus in patients with temporal lobe epilepsy. Our data do not confirm previous work, which suggested serum S-100 protein to be a suitable marker for epileptic seizures. [source] Quality of Governance: Impartiality Is Not EnoughGOVERNANCE, Issue 2 2008FRANCISCO LONGO First page of article [source] When Being Thin Is Not a VirtueJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 12 2008David S. Knopman MD No abstract is available for this article. [source] The National Institute on Aging's Mission Is Not 1970s NostalgiaJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 8 2003PharmD, Todd P. Semla MS No abstract is available for this article. [source] Preoperative Atrial Cardiomyocyte Ionic Currents and Postoperative AF: Important Insights Into What Is Not the MechanismJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 11 2006STANLEY NATTEL M.D.Article first published online: 21 SEP 200 No abstract is available for this article. [source] High Blood Pressure in Children and Adolescents: To Treat or Not to Treat Is Not the QuestionJOURNAL OF CLINICAL HYPERTENSION, Issue 12 2008George A. Mensah MD First page of article [source] Evidence That Gonadotropin-Releasing Hormone II Is Not a Physiological Regulator of Gonadotropin Secretion in MammalsJOURNAL OF NEUROENDOCRINOLOGY, Issue 9 2003P. M. Gault Abstract Gonadotropin-releasing hormone (GnRH)-II stimulates luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion when administered at high doses in mammals, and this effect has been assumed to be mediated through the GnRH-II receptor expressed on gonadotropes. This study used two selective GnRH-I receptor antagonists to test the alternative hypothesis that GnRH-II acts through the GnRH-I receptor to elicit gonadotropin secretion. The antagonist, antide, was used to characterize the receptor-relay because it was a pure antagonist in vitro based on inositol phosphate responses in COS-7 cells transfected with either mammalian GnRH-I and GnRH-II receptors and, in vivo, potently antagonized the gonadotropin-releasing effect of a single injection of 250 ng GnRH-I in our sexually inactive sheep model. In a series of studies in sheep, antide (i) blocked the acute LH response to a single injection of GnRH-II (20 µg antide: 10 µg GnRH-II); (ii) blocked both the acute, pulsatile LH response and the FSH priming response to 2-hourly injections of GnRH-II over 36 h (100 µg antide/8 h: 4 µg GnRH-II/2 h); and (iii) chronically blocked both the pulsatile LH response and the marked FSH priming response to 4-hourly injections of GnRH-II over 10 days (75 µg antide/8 h: 4 µg GnRH-II/4 h). In two final experiments, the GnRH-I antagonist 135-18, shown previously to agonize the mammalian GnRH-II receptor, blocked the gonadotropin-releasing effects of GnRH-I (250 ng) but failed to elicit an LH response when given alone, and simultaneous administration of GnRH-II (250 ng) failed to alter the LH-releasing effect of GnRH-I (50,500 ng). These data thus support our hypothesis. Based on additional literature, it is unlikely that the GnRH-II decapeptide is a native regulator of the gonadotrope in mammals. [source] God Is Not a Story: Realism Revisited , By Francesca Aran MurphyMODERN THEOLOGY, Issue 3 2008William C. Placher No abstract is available for this article. [source] "Kissing a Baby Is Not at All Good for Him": Infant Mortality, Medicine, and Colonial Modernity in the U.S.-Occupied PhilippinesAMERICAN ANTHROPOLOGIST, Issue 2 2005BONNIE McELHINNY Feminist scholars have begun to consider the ways indigenous practices of child rearing were and are challenged in (post)colonial discourse and practice, and how these practices have become a terrain on which definitions of nation, state, and economy are contested. In this article, I adopt a historical anthropological approach to consider how Filipino child-rearing strategies were described and stigmatized in educational, public health, and public welfare discourses in the U.S.-occupied Philippines in the early 20th century. I demonstrate how public health practices and discourses that were generated as part of a "benevolent" campaign against high rates of infant mortality were strategically used as a weapon against Filipino arguments for independence. I also consider how discourses constructing Filipino caregivers as overly indulgent were linked to metropolitan concerns about production of the "new industrial man" and were used to develop a racialized critique of the cultural practices of Filipinos. [source] Iran Is Not a Suicide StateNEW PERSPECTIVES QUARTERLY, Issue 4 2008GEN. JOHN ABIZAID First page of article [source] Turkey's Secularism Is Not the Answer for Islamic StatesNEW PERSPECTIVES QUARTERLY, Issue 2 2003Mohamad Mahathir No abstract is available for this article. [source] COUNTERPOINT: Mechanical Treatment of Atherosclerosis Is Not a CurePREVENTIVE CARDIOLOGY, Issue 4 2009William R. Lewis MD No abstract is available for this article. [source] Desire for Castration Is Not a Body Integrity Identity Disorder: Comment on Johnson et al. (2007), Brett et al. (2007), and Roberts et al. (2008)THE JOURNAL OF SEXUAL MEDICINE, Issue 2pt1 2010Anne A. Lawrence No abstract is available for this article. [source] Snoring Is Not an Exclusion Criteria; It Is Placed Into the Obstructive Sleep Apnea CategoryTHE LARYNGOSCOPE, Issue 6 2006Adriane I. Zonato MD No abstract is available for this article. [source] Gadolinium Is Not the Only Trigger for Nephrogenic Systemic Fibrosis: Insights From Two Cases and Review of the Recent LiteratureAMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2007I. M. Wahba Nephrogenic systemic fibrosis (NSF) is an emerging fibrosing disease with serious consequences in patients with acute and chronic kidney disease including solid organ and renal transplant recipients. It has recently been linked to gadolinium exposure. Almost all recently reported cases of NSF were found to be preceded by gadolinium administration, which led the FDA to issue a warning against the use of gadolinium in patients with moderate-to-severe reduction in the glomerular filtration rate. We report two organ transplant recipients who developed NSF and in whom extensive record review failed to document any prior gadolinium exposure. We then critically review the recently published literature linking NSF and gadolinium and we propose other possible triggers. We conclude that gadolinium is not the only trigger for NSF, and that the search for other triggers should be sought. We believe that this information is an important addition to the NSF literature, such that the definitive etiology and pathogenesis of NSF can be researched. [source] SIRS Is Not a Playful ActACADEMIC EMERGENCY MEDICINE, Issue 8 2009Jonathan Singer MD No abstract is available for this article. [source] WT1 Is Not a Reliable Marker to Distinguish Reactive from Neoplastic Astrocyte Populations in the Central Nervous SystemBRAIN PATHOLOGY, Issue 6 2010T. David Bourne MD Abstract A diagnostic difficulty in neuropathology practice is distinguishing reactive from neoplastic astrocyte populations. This is particularly true in small biopsy samples that lack evidence of increased cellularity or mitotic activity, microvascular proliferation, or necrosis. We performed the current study to validate the previously reported finding that in the central nervous system, the expression of WT1 is limited to neoplastic astrocytes. We retrospectively studied WT1 protein expression by immunohistochemistry (IHC) in 100 formalin-fixed, paraffin-embedded brain tissue samples consisting of 3 normal control tissues, 44 cases of reactive gliosis, 49 gliomas and 4 lesions suspicious for glioma. In normal human cortex, WT1 staining was restricted to vascular endothelium. Most cases of reactive gliosis (82%) showed at least focal WT1 positivity, and analysis of specimens with electrode monitoring lesions showed an inverse relationship between WT1 expression intensity and the number of days from electrode placement to tissue resection. All glioma samples (100%) and all cases suspicious for glioma (100%) showed at least focal WT1 positivity. Our results likely differ from those in the prior report because of differences in tissue fixation and IHC methodology. Thus, our findings indicate that WT1 expression alone is not a reliable feature to distinguish reactive from neoplastic astrocytes. [source] Evolution Is Not a Necessary Assumption of CladisticsCLADISTICS, Issue 1 2000Andrew V.Z. Brower Although the point has already been emphasized by various authors that the assumption of descent with modification is not required to justify cladistics, recent debate suggests that there is still confusion surrounding the necessary and sufficient background knowledge underlying the method. Three general axioms necessary to justify cladistics,the discoverability of characters, hierarchy, and parsimony,are reviewed. Although the assumption of evolution is sufficient to justify cladistics, it is also sufficient to justify competing approaches like maximum likelihood, which suggests that the philosophical support for the cladistic approach is strengthened by purging reference to descent with modification altogether. [source] | ||||||||||||||||