Is It (be + it)

Distribution by Scientific Domains

Terms modified by Is It

  • be it possible
  • be it time

  • Selected Abstracts


    Capital Allocation for Insurance Companies,What Good IS IT?

    JOURNAL OF RISK AND INSURANCE, Issue 2 2007
    Helmut Gründl
    In their 2001 Journal of Risk and Insurance article, Stewart C. Myers and James A. Read Jr. propose to use a specific capital allocation method for pricing insurance contracts. We show that in their model framework no capital allocation to lines of business is needed for pricing insurance contracts. In the case of having to cover frictional costs, the suggested allocation method may even lead to inappropriate insurance prices. Beside the purpose of pricing insurance contracts, capital allocation methods proposed in the literature and used in insurance practice are typically intended to help derive capital budgeting decisions in insurance companies, such as expanding or contracting lines of business. We also show that net present value analyses provide better capital budgeting decisions than capital allocation in general. [source]


    Crescent Versus Rectangle: Is It a True Negative Margin in Second and Subsequent Stages of Mohs Surgery?

    DERMATOLOGIC SURGERY, Issue 2 2010
    YUE YU MD
    BACKGROUND The hallmark of Mohs micrographic surgery is using tangential tissue sections that theoretically allow 100% of the tissue margin to be examined, but when taking additional layers for second and subsequent Mohs stages, no detailed methods have been described to ensure that 100% of the tissue margins are analyzed. METHOD A rectangular or a crescent-shaped layer is often used to take second and subsequent stages. Here we compare the two techniques for their theoretic advantages and disadvantages. SUMMARY The advantage of the rectangular shape has been ease of processing, as well as built in vertical "nicks" that automatically mark the border of the tissue removed, but the rectangular layer may not provide 100% evaluation of the tumor margin because the vertical edges of the rectangular layer are not always completely analyzed, and thus tumor cells cannot be visualized in the vertical margins of these layers. This might result in a false-negative margin reading, which can be avoided by using the crescent layer. CONCLUSION We propose taking second and subsequent Mohs layers with only a crescent shape, which allows true 100% tissue margin assessment. The authors have indicated no significant interest with commercial supporters. [source]


    Aortic Valve Sclerosis: Is It a Cardiovascular Risk Factor or a Cardiac Disease Marker?

    ECHOCARDIOGRAPHY, Issue 3 2007
    F.I.S.C.U., Pasquale Palmiero M.D.
    Background: Aortic valve sclerosis, without stenosis, has been associated with an increased cardiovascular mortality and morbidity due to myocardial infarction. However, it is unclear whether it is a cardiovascular risk factor or a cardiac disease marker. The goal of our study is to evaluate the difference in the prevalence of cardiovascular disease and risk factors among patients with or without aortic sclerosis. Methods: This observational study compared a group of 142 consecutive subjects with aortic valve sclerosis, assigned as group S, with a group of 101 subjects without aortic sclerosis, assigned as group C. Patients with bicuspid aortic valves and those with antegrade Doppler velocity across aortic valve leaflets exceeding 2.0 m/sec were excluded. Results: Mean ages of groups S and C were 71 ± 8, and 68.8 ± 6 years, respectively (P value = not significant). The prevalence of smoking, diabetes, hypercholesterolemia, hypertension, pulse pressure, left ventricular diastolic dysfunction, atrial fibrillation, and stroke was not significantly different between the two groups. However, there was a significantly higher prevalence of left ventricular hypertrophy (P = 0.05), ventricular arrhythmias (P = 0.02), myocardial infarction (P = 0.04), and systolic heart failure (P = 0.04) in aortic sclerosis group. Conclusions: Aortic sclerosis is associated with a higher prevalence of left ventricular hypertrophy, ventricular arrhythmias, myocardial infarction, and systolic heart failure, while the prevalence of cardiovascular risk factors is not different between aortic sclerosis patients and controls. Hence, aortic sclerosis represents a cardiac disease marker useful for early identification of high-risk patients beyond cardiovascular risk factors rate. [source]


    Is It Open or Is It Closed?

    ECHOCARDIOGRAPHY, Issue 4 2002
    Thrombosis of a St. Jude's Tricuspid Valve Prosthesis
    A 49-year-old woman with mitral and tricuspid mechanical valve prostheses developed marked weight gain with increasing abdominal girth and facial plethora 4 weeks after anticoagulation was temporarily interrupted for abdominal surgery. Transthoracic and transesophageal echocardiography documented severe tricuspid stenosis and regurgitation. The two discs of the tricuspid prosthesis were immobilized, half open and half closed. The prosthesis was replaced and the patient did well. [source]


    Generic Products of Antiepileptic Drugs (AEDs): Is It an Issue?

    EPILEPSIA, Issue 10 2007
    Meir Bialer
    Summary:, The availability of generic products of antiepileptic drugs (AEDs) has raised the following concerns: (1) Do generic AEDs work as well as brand AEDs in terms of their efficacy, safety and quality? (2) Can generic AEDs be used as substitutions for brand AEDs? and (3) Can generic products of AEDs be used interchangeably? The traditional average bioequivalence analysis addresses concern 1 but does not provide a complete adequate response to concerns 2 and 3. Drug interchangeability can be classified as drug prescribability or drug switchability. Drug prescribability refers to the situation where a patient is treated for the first time so that either a brand or a bioequivalent generic AED can be chosen. Drug switchability refers to the situation in which a brand AED is switched to a bioequivalent generic product of the same AED. The traditional average bioequivalence approach is sufficient to evaluate the prescribability of generic products, but does not ensure the switchability between prescribable formulations. The necessity of assuring switchability of two formulations can be addressed by individual bioequivalence. While the switch to generic AEDs is well tolerated by many patients and in general cost-effective, seizure control should not be sacrificed on the basis of cost alone, as the major end point in treating epilepsy with AEDs is seizure control without side effects. Until we have individual (within patient) bioequivalence data on generic AEDs and/or the tools to a priori identify the subset of patients susceptible to the generic switch, a switch of AED products in seizure-free patients is not recommended. [source]


    Almotriptan Efficacy in Migraine With Developing Allodynia Is as High as the Efficacy in Migraine Without Allodynia , But Is It the Same in Migraine With Established Allodynia?

    HEADACHE, Issue 3 2009
    Rami Burstein PhD
    No abstract is available for this article. [source]


    Is the "Third-Generation Model" New and Is It the Holy Grail of Adaptive Learning?

    INDUSTRIAL AND ORGANIZATIONAL PSYCHOLOGY, Issue 4 2008
    ALAN M. SAKS
    [source]


    Mezzanine Financing: Is It for You?

    JOURNAL OF CORPORATE ACCOUNTING & FINANCE, Issue 2 2008
    LuAnn Bean
    Companies that want to finance a leveraged buyout (LBO) should consider mezzanine financing. This can fill the gap between low-risk collateralized debt, obtained from traditional lenders, and higher-risk equity interests. But what are the pros and cons of this kind of financing? Is it a good option for your company? The author reveals what you should know before committing to this financial arrangement. © 2008 Wiley Periodicals, Inc. [source]


    Peer Review: What Is It and Where Did It Come from?

    JOURNAL OF PROSTHODONTICS, Issue 3 2008
    How Does It Relate to Publication in the JOPR?
    [source]


    Public Participation in Environmental Decision Making: Is It Working?

    NATIONAL CIVIC REVIEW, Issue 2 2002
    Matthew McKinney
    [source]


    Vitamin A: Is It a Risk Factor for Osteoporosis and Bone Fracture?

    NUTRITION REVIEWS, Issue 10 2007
    Judy D. Ribaya-Mercado ScD
    Results from observational studies of the association between vitamin A intake or serum concentration and bone mineral density or fracture are mixed. The inconsistencies may be due, in part, to difficulties in obtaining an accurate assessment of vitamin A intake or status. Serum retinol is a poor measure of vitamin A status because it is subject to homeostatic control. Stable-isotope-dilution methodology gives a validated assessment of the total-body and liver vitamin A stores and is recommended in future studies on vitamin A status and osteoporosis. The potential for exacerbating an already serious public health problem with intakes of vitamin A currently considered safe indicates further research into this matter is warranted. [source]


    What Is Quality, and Who Is It for?

    AMERICAN JOURNAL OF ORTHOPSYCHIATRY, Issue 3 2003
    Ernest Joel Millman PhD
    No abstract is available for this article. [source]


    Emerging Adulthood: What Is It, and What Is It Good For?

    CHILD DEVELOPMENT PERSPECTIVES, Issue 2 2007
    Jeffrey Jensen Arnett
    ABSTRACT,This article asserts that the theory of emerging adulthood is a useful way of conceptualizing the lives of people from their late teens to their mid- to late 20s in industrialized societies. The place of emerging adulthood within the adult life course is discussed. The weaknesses of previous terms for this age period are examined, and emerging adulthood is argued to be preferable as a new term for a new phenomenon. With respect to the question of whether emerging adulthood is experienced positively or negatively by most people, it is argued that it is positive for most people but entails developmental challenges that may be difficult and there is great heterogeneity, with some emerging adults experiencing serious problems. With respect to the question of whether or not emerging adulthood is good for society, it is argued that claims of the dangers of emerging adulthood are overblown, but emerging adulthood is probably a mixed blessing for society. [source]


    The Arctic Cooking Pot: Why Was It Adopted?

    AMERICAN ANTHROPOLOGIST, Issue 3 2009
    Karen Harry
    ABSTRACT Cross-culturally, clay cooking pots are correlated with societies situated in warm and dry climates and reliant on foods that benefit from prolonged moist cooking. Neither of these conditions, however, characterized the aboriginal coastal Arctic, where clay cooking containers were produced and used for more than 2,500 years. We explore the factors that encouraged pottery use in the Arctic and conclude that the adoption of cooking pots resulted from the interplay of social and functional factors. We propose that it was adopted (1) to meet the needs of socially constructed preferences for cooked foods and (2) to overcome specific problems associated with other cooking methods within the local social and environmental context. We demonstrate the importance of adopting an integrated perspective in the study of technology,one that considers how cultural values and social practices interact with environmental and economic factors to shape technological decisions. [source]