Traditional Sources (traditional + source)

Distribution by Scientific Domains


Selected Abstracts


The treasurer: How to weather our current crisis

JOURNAL OF CORPORATE ACCOUNTING & FINANCE, Issue 1 2009
Asokan Anandarajan
We are enduring the worst financial crisis since the Great Depression. Traditional sources of liquidity and investments have dried up. And we are living in a state of flux, where the rules can be changed overnight,as the federal government constantly announces new amendments to the bailout plans. So, the role of the treasurer has changed from managing liquidity to managing emergencies. What special hazards must the treasurer now avoid? And what strategies can he or she adopt to weather the current storm? © 2009 Wiley Periodicals, Inc. [source]


Manufacturing of human placenta-derived mesenchymal stem cells for clinical trials

BRITISH JOURNAL OF HAEMATOLOGY, Issue 4 2009
Gary Brooke
Summary Mesenchymal stem cells (MSC) are being used increasingly in clinical trials for a range of regenerative and inflammatory diseases. Bone marrow is the traditional source but is relatively inaccessible in large volume. MSC have now been derived from tissues other than bone marrow including placenta and adipose tissue. We have used placenta obtained after delivery as a source of MSC and have been unable to detect any marked differences from marrow-derived MSC in terms of cell surface phenotype, chemokine receptor display, mesodermal differentiation capacity or immunosuppressive ability. This report described our manufacturing process for isolating and expanding placenta-derived human MSC and their safe infusion into the first patient in a clinical trial program of human placenta-derived MSC. [source]


Survey of computer use for health topics by patients with head and neck cancer

HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 1 2005
Jane Lea BSc
Abstract Background. Computers are potentially powerful tools for patient education. E-health, which refers to health services and information delivered through the Internet, is a growing phenomenon within the health-care field. We sought to describe computer use and interest in e-health resources among patients with head and neck cancer. Methods. A questionnaire was administered to 207 patients with head and neck cancer attending oncology follow-up clinics at a single comprehensive cancer center. Results. Forty-eight percent had never used a computer; 43% used one more than once a week. E-health information had been sought by 31%. Likelihood to access e-health information increased with education and income but decreased with age (p , .05). Conclusions. Many patients with head and neck cancer welcome information technology, but most prefer more traditional sources of information. Interventions to improve computer access and/or skills are largely undesired. Individuals seem to either embrace technology or not. In this respect, patients with head and neck cancer are similar to, rather than unique from, other patients with cancer. © 2004 Wiley Periodicals, Inc. Head Neck27: 8,14, 2005 [source]


Principles of evidence-based management using stage I,II melanoma as a model

INTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 11 2002
Tsu-Yi Chuang MD
Evidence-Based Medicine (EBM) is the practice of integrating best research evidence with clinical expertise and patent values. 1 The term, Evidence-Based Medicine, was named in 1992 by a group led by Gordon Guyatt at McMaster University in Canada. The practice of EBM arose from the awareness of: 1the daily need for valid information pertinent to clinical practice; 2the inadequacy of traditional sources, like textbooks, for such information; 3the disparity between clinical enhancing skills and declining up-to-date knowledge and eventually, clinical performance; and 4the inability to spend more time in finding and assimilating evidence pertinent to clinical practice. EBM simply emphasizes three As: Access, Appraisal and Application. Access requires refining a clinical question into a searchable term and an answerable question and using search engines to track down the information. Appraisal is using epidemiological principles and methods to critically review evidence for its validity and applicability. Application is integrating the critically appraised evidence with clinical expertise and each patient's unique situation. The outcomes following such practices are then assayed. The last step involves evaluating the effectiveness and efficiency in executing the first two As and seeking ways for improvement. In this article, we describe the concept and steps of practising EBM and utilize melanoma as an example to illustrate how we integrate the best evidence to outline the management plan for stage I-II melanoma. [source]


Religious Authority and the Blogosphere

JOURNAL OF COMPUTER-MEDIATED COMMUNICATION, Issue 2 2010
Heidi A. Campbell
It is often argued that the internet poses a threat to traditional forms of authority. Within studies of religion online claims have also been made that the internet is affecting religious authority online, but little substantive work has backed up these claims. This paper argues for an approach to authority within online studies which looks separately at authority: roles, structures, beliefs/ideologies and texts. This approach is applied to a thematic analysis of 100 religious blogs and demonstrates that religious bloggers use their blogs to frame authority in ways that may more often affirm than challenge traditional sources of authority. [source]


Financing Small Technology-Based Companies: The Relationship between Familiarity with Capital and Ability to Price and Negotiate Investment

JOURNAL OF SMALL BUSINESS MANAGEMENT, Issue 3 2001
Howard E. Van Auken
This study examines the financing of small technology-based firms. Specifically, the study investigates the familiarity of owners of small technology-based firms with alternative forms of capital by stage of development and in comparison with their ability to price and negotiate external equity and debt investment. The results indicate that owners are most familiar with traditional sources of capital, somewhat less familiar with capital commonly used to fund growth, and least familiar with government funding initiatives. Owners believe that they are better able to negotiate than to price equity and debt. The perceived ability to negotiate and price externally funded investments increases as the firm matures through the various stages of development. [source]


Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities

ACADEMIC EMERGENCY MEDICINE, Issue 11 2009
Gail D'Onofrio MD
Abstract The emergency department (ED) visit provides an opportunity to impact the health of the public throughout the entire spectrum of care, from prevention to treatment. As the federal government has a vested interest in funding research and providing programmatic opportunities that promote the health of the public, emergency medicine (EM) is prime to develop a research agenda to advance the field. EM researchers need to be aware of federal funding opportunities, which entails an understanding of the organizational structure of the federal agencies that fund medical research, and the rules and regulations governing applications for grants. Additionally, there are numerous funding streams outside of the National Institutes of Health (NIH; the primary federal health research agency). EM researchers should seek funding from agencies according to each agency's mission and aims. Finally, while funds from the Department of Health and Human Services (HHS) are an important source of support for EM research, we need to look beyond traditional sources and appeal to other agencies with a vested interest in promoting public health in EDs. EM requires a broad skill set from a multitude of medical disciplines, and conducting research in the field will require looking for funding opportunities in a variety of traditional and not so traditional places within and without the federal government. The following is the discussion of a moderated session at the 2009 Academic Emergency Medicine consensus conference that included panel discussants from the National Institutes of Mental Health, Drug Abuse, and Alcoholism and Alcohol Abuse and the Centers for Disease Control and Prevention (CDC). Further information is also provided to discuss those agencies and centers not represented. [source]


Case-controlled structure validation

ACTA CRYSTALLOGRAPHICA SECTION D, Issue 2 2009
Randy J. Read
Although many factors influence the quality of a macromolecular crystal structure, validation criteria are usually only calibrated using one of these factors, the resolution. For many purposes this is sufficient, but there are times when one wishes to compare one set of structures with another and the comparison may be invalidated by systematic differences between the sets in factors other than resolution. This problem can be circumvented by borrowing from medicine the idea of the case-matched control: each structure of interest is matched with a control structure that has similar values for all relevant factors considered in this study. In addition to resolution, these include the size of the structure (as measured by the volume of the asymmetric unit) and the year of deposition. This approach has been applied to address two questions: whether structures from structural genomics efforts reach the same level of quality as structures from traditional sources and whether the impact factor of the journal in which a structure is published correlates with structure quality. In both cases, once factors influencing quality have been controlled in the comparison, there is little evidence for a systematic difference in quality. [source]