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Kinds of Toronto Terms modified by Toronto Selected AbstractsEMBEDDED CONTRASTS IN RACE, MUNICIPAL FRAGMENTATION, AND PLANNING: DIVERGENT OUTCOMES IN THE DETROIT AND GREATER TORONTO,HAMILTON REGIONS 1990,2000JOURNAL OF URBAN AFFAIRS, Issue 2 2009A. J. JACOBS ABSTRACT:,Since the early 1980s, scholars have debated whether or not the converging forces of globalization have disembedded city-regions from their national contexts. This study explored this question through a comparison of post-1990 growth trends in the Detroit and Greater Toronto Area,Hamilton regions (GTAH), two urban areas within the same natural region and closely linked by industrial production flows, yet politically situated within two separate Federalist states. Guided by Nested City Theory, it reveals how their dissimilar contexts for race, local autonomy, and multilocal planning have helped foster divergent spatial patterns in the two regions. In particular, provincial controls governing municipal fragmentation, Ontario's Planning Act, and subregional/microregional planning have been key embedded structures helping to limit population decline and disinvestment in GTAH core cities. In the process, this article shows how urban trajectories have remained nested within multilevel spatial and institutional configurations. Its findings also call for greater consideration of nested state/provincial factors in cross-national comparisons of cities within Federal states. Finally, its conclusion offers a starting point toward a more nuanced specific version of Nested Theory to be called the Contextualized Model of Urban,Regional Development. [source] Surge Capacity Associated with Restrictions on Nonurgent Hospital Utilization and Expected Admissions during an Influenza Pandemic: Lessons from the Toronto Severe Acute Respiratory Syndrome OutbreakACADEMIC EMERGENCY MEDICINE, Issue 11 2006Michael J. Schull MD Background Current influenza pandemic models predict a surge in influenza-related hospitalizations in affected jurisdictions. One proposed strategy to increase hospital surge capacity is to restrict elective hospitalizations, yet the degree to which this measure would meet the anticipated is unknown. Objectives To compare the reduction in hospitalizations resulting from widespread nonurgent hospital admission restrictions during the Toronto severe acute respiratory syndrome (SARS) outbreak with the expected increase in admissions resulting from an influenza pandemic in Toronto. Methods The authors compared the expected influenza-related hospitalizations in the first eight weeks of a mild, moderate, or severe pandemic with the actual reduction in the number of hospital admissions in Toronto, Ontario, during the first eight weeks of the SARS-related restrictions. Results Influenza modeling for Toronto predicts that there will be 4,819, 8,032, or 11,245 influenza-related admissions in the first eight weeks of a mild, moderate, or severe pandemic, respectively. In the first eight weeks of SARS-related hospital admission restrictions, there were 3,654 fewer hospitalizations than expected in Toronto, representing a modest 12% decrease in the overall admission rate (a reduction of 1.40 admissions per 1,000 population). Therefore, influenza-related admissions could exceed the reduction in admissions resulting from restricted hospital utilization by 1,165 to 7,591 patient admissions, depending on pandemic severity, which corresponds to an excess of 0.44 to 2.91 influenza-related admissions per 1,000 population per eight weeks, and an increase of 4% to 25% in the overall number of admissions, when compared with nonpandemic conditions. Conclusions Pandemic modeling for Toronto suggests that influenza-related admissions would exceed the reduction in hospitalizations seen during SARS-related nonurgent hospital admission restrictions, even in a mild pandemic. Sufficient surge capacity in a pandemic will likely require the implementation of other measures, including possibly stricter implementation of hospital utilization restrictions. [source] School attendance in children with Type 1 diabetesDIABETIC MEDICINE, Issue 4 2005L. A. Glaab Abstract Aims To determine whether children with Type 1 diabetes mellitus (DM) miss more school than their non-DM siblings and peers and to identify factors associated with school absenteeism in children with DM. Methods School absenteeism data for the 2000,01 school year were obtained for 78 children with DM, 38 non-DM siblings and 118 269 age-matched peers in Toronto, Ontario. Questionnaires and hospital records were utilized to evaluate child-, family- and diabetes-related factors associated with school absenteeism in children with DM. Results Children with DM missed only slightly, albeit significantly more school than both their non-DM siblings (mean ±sd: 10.9 ± 8.9 vs. 8.1 ± 8.1 days, P < 0.001) and peers (median: 8.8 vs. 5.5 days, P = 0.0005). A multiple regression analysis indicated that school absenteeism in children with DM was associated with their parents' attitudes towards school attendance (P = 0.002), poorer metabolic control (P = 0.006), shorter disease duration (P = 0.006) and a lack of aggressive behaviour (P = 0.02). Conclusions With current management strategies, near normal school attendance is a reasonable goal for all children with DM and should be strongly encouraged by parents, educators and health care professionals. [source] Differentiation of structural isomers in a target drug database by LC/Q-TOFMS using fragmentation predictionDRUG TESTING AND ANALYSIS, Issue 6 2010Elli Tyrkkö Abstract Isomers cannot be differentiated from each other solely based on accurate mass measurement of the compound. A liquid chromatography/quadrupole time-of-flight mass spectrometry (LC/Q-TOFMS) method was used to systematically fragment a large group of different isomers. Two software programs were used to characterize in silico mass fragmentation of compounds in order to identify characteristic fragments. The software programs employed were ACD/MS Fragmenter (ACD Labs Toronto, Canada), which uses general fragmentation rules to generate fragments based on the structure of a compound, and SmartFormula3D (Bruker Daltonics), which assigns fragments from a mass spectra and calculates the molecular formulae for the ions using accurate mass data. From an in-house toxicology database of 874 drug substances, 48 isomer groups comprising 111 compounds, for which a reference standard was available, were found. The product ion spectra were processed with the two software programs and 1,3 fragments were identified for each compound. In 82% of the cases, the fragment could be identified with both software programs. Only 10 isomer pairs could not be differentiated from each other based on their fragments. These compounds were either diastereomers or position isomers undergoing identical fragmentation. Accurate mass data could be utilized with both software programs for structural elucidation of the fragments. Mean mass accuracy and isotopic pattern match values (SigmaFit; Bruker Daltonics Bremen, Germany) were 0.9 mDa and 24.6 mSigma, respectively. The study introduces a practical approach for preliminary compound identification in a large target database by LC/Q-TOFMS without necessarily possessing reference standards. Copyright © 2010 John Wiley & Sons, Ltd. [source] Intraoperative Transesophageal Echocardiography in Congenital Heart DiseaseECHOCARDIOGRAPHY, Issue 8 2002F.R.A.C.P., F.R.C.P.(C.)Article first published online: 24 JUL 200, Jeffrey F. Smallhorn M.B.B.S. Intraoperative transesophageal echocardiography has become an integral component of the repair of congenital heart defects. It currently has a direct impact on reducing morbidity and mortality in the pediatric cardiac population. To establish a successful program, it is important to follow guidelines for training as well as having a systematic approach to the evaluation of this patient population. This article addresses the specific indications in a patient population as practiced at the Hospital For Sick Children, Toronto. While there may be subtle differences between programs, the objectives are to provide excellent service to the pediatric cardiac patient in the operating room. [source] Countervailing Immigration and Domestic Migration in Gateway Cities: Australian and Canadian Variations on an American ThemeECONOMIC GEOGRAPHY, Issue 3 2007David Ley Abstract: This article addresses the spatial regularity of countervailing population flows of immigration and net domestic migration, respectively, into and out of large gateway cities. This regularity has been noted most often in the United States, and the argument presented here makes two new contributions. First, it extends the analysis to the principal Australian and Canadian gateway cities of Sydney and Toronto, making use of an extended time series of annual data. Second, it argues for the importance of the neglected effects of housing markets, in contrast to conventional accounts that stress cultural avoidance or labor market competition, in differentiating the two demographic streams. The article shows how trends in the housing market separate the locational preferences of immigrants from two diverse groups of domestic migrants. [source] A cautionary note on the use of species presence and absence data in deriving sediment criteriaENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 2 2002Katherine Von Stackelberg Abstract In recent years, a variety of approaches to deriving sediment quality guidelines have been developed. One approach relies on establishing an empirical relationship between the concentration of a contaminant in sediment and the condition of some biological indicator, for example, combining measured sediment concentrations of contaminants combined with data on colocated benthic species to measure in situ community effects of contamination. Biological threshold concentrations derived in this manner are being considered or have already been adopted by some regulatory agencies as a means for deriving sediment guidelines (e.g., Canada's Provincial Sediment Quality Guidelines). In order to test the validity of this method, we constructed several Monte Carlo simulations to illustrate that the methodology used to develop these guidelines is flawed by the effects of sampling and statistical artifacts that emerge from undersampling a lognormal density function. As a case study, this paper will present the screening level concentration method used by the Ontario Ministry of the Environment (Toronto, ON, Canada) and provide the results of several probabilistic exercises highlighting these issues. We present a word of caution on the applicability of methods that rely exclusively on statistical and mathematical relationships between invertebrate data and sediment concentrations to derive sediment quality guidelines. [source] Guardians and handlers: the role of bar staff in preventing and managing aggressionADDICTION, Issue 6 2005Kathryn Graham ABSTRACT Aims To identify good and bad behaviors by bar staff in aggressive incidents, the extent these behaviors apparently reflect aggressive intent, and the association of aggressive staff behavior with level of aggression by patrons. Design, setting and participants Data on staff behavior in incidents of aggression were collected by 148 trained observers in bars and clubs on Friday and Saturday night between midnight and 2 a.m. in Toronto, Canada. Behaviors of 809 staff involved in 417 incidents at 74 different bars/clubs were analysed using descriptive statistics and three-level hierarchical linear modeling (HLM) analyses. Measurements Observers' ratings of 28 staff behaviors were used to construct two scales that measured escalating/aggressive aspects of staff behavior. Apparent intent level for bar staff was dichotomized into (1) no aggressive intent versus (2) probable or definite aggressive intent. Five levels of patron aggression were defined: no aggression, non-physical, minor physical, moderate physical and severe physical. Findings The most common aggressive behaviors of staff were identified. Staff were most aggressive when patrons were either non-aggressive or highly aggressive and staff were least aggressive when patrons exhibited non-physical aggression or minor physical aggression. Taking apparent intent into consideration decreased staff aggression scores for incidents in which patrons were highly aggressive indicating that some aggression by staff in these instances had non-aggressive intent (e.g. to prevent injury); however, apparent intent had little effect on staff aggression scores in incidents with non-aggressive patrons. Conclusion Although there is potential for staff to act as guardians or handlers, they often themselves became offenders when they responded to barroom problems. The practical implications are different for staff aggression with nonaggressive patrons versus with aggressive patrons. [source] SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARSEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 7 2009G. Y. Oudit Abstract Background, Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1,7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease including arrhythmias, sudden cardiac death, and systolic and diastolic dysfunction. Materials and methods, We studied mice infected with the human strain of the SARS-CoV and encephalomyocarditis virus and examined ACE2 mRNA and protein expression. Autopsy heart samples from patients who succumbed to the SARS crisis in Toronto (Canada) were used to investigate the impact of SARS on myocardial structure, inflammation and ACE2 protein expression. Results, Pulmonary infection with the human SARS-CoV in mice led to an ACE2-dependent myocardial infection with a marked decrease in ACE2 expression confirming a critical role of ACE2 in mediating SARS-CoV infection in the heart. The SARS-CoV viral RNA was detected in 35% (7/20) of autopsied human heart samples obtained from patients who succumbed to the SARS crisis during the Toronto SARS outbreak. Macrophage-specific staining showed a marked increase in macrophage infiltration with evidence of myocardial damage in patients who had SARS-CoV in their hearts. The presence of SARS-CoV in the heart was also associated with marked reductions in ACE2 protein expression. Conclusions, Our data show that SARS-CoV can mediate myocardial inflammation and damage associated with down-regulation of myocardial ACE2 system, which may be responsible for the myocardial dysfunction and adverse cardiac outcomes in patients with SARS. [source] Molecular cytogenetic characterization of non-Hodgkin lymphoma cell linesGENES, CHROMOSOMES AND CANCER, Issue 3 2002Sukvarsha Mehra Spectral karyotyping (SKY) and comparative genomic hybridization (CGH) have greatly enhanced the resolution of cytogenetic analysis, enabling the identification of novel regions of rearrangement and amplification in tumor cells. Here we report the analysis of 10 malignant non-Hodgkin lymphoma (NHL) cell lines derived at the Ontario Cancer Institute (OCI), Toronto, designated as OCI-Ly1, OCI-Ly2, OCI-Ly3, OCI-LY4, OCI-Ly7, OCI-Ly8, OCI-Ly12, OCI-Ly13.2, OCI-Ly17, and OCI-Ly18, by G-banding, SKY, and CGH, and we present their comprehensive cytogenetic profiles. In contrast to the 52 breakpoints identified by G-banding, SKY identified 87 breakpoints, which clustered at 1q21, 7p15, 8p11, 13q21, 13q32, 14q32, 17q11, and 18q21. G-banding identified 10 translocations, including the previously described recurring translocations, t(8;14)(q24;q32) and t(14;18)(q32;q21). In contrast, SKY identified 60 translocations, including five that were recurring, t(8;14)(q24;q32), t(14;18)(q32;q21), t(4;7)(p12;q22), t(11;18)(q22;q21), and t(3;18)(q21;p11). SKY also identified the source of all the marker chromosomes. In addition, 10 chromosomes that were classified as normal by G-banding were found by SKY to be rearranged. CGH identified seven sites of high-level DNA amplification, 1q31-32, 2p12-16, 8q24, 11q23-25, 13q21-22, 13q32-34, and 18q21-23; of these, 1q31-32, 11q23-25, 13q21-22, and 13q32-34 have previously not been described as amplified in NHL. This comprehensive cytogenetic characterization of 10 NHL cell lines identified novel sites of rearrangement and amplification; it also enhances their value in experimental studies aimed at gene discovery and gene function. © 2002 Wiley-Liss, Inc. [source] TENDING CULTURAL LANDSCAPES AND FOOD CITIZENSHIP IN TORONTO'S COMMUNITY GARDENS,GEOGRAPHICAL REVIEW, Issue 3 2004LAUREN E. BAKER ABSTRACT. Scattered throughout the city of Toronto are more than no community gardens, sites of place-based politics connected to the community food-security movement. The gardens, spaces where passions for plants and food are shared, reflect the city's shifting cultural landscape and represent an everyday activity that is imbued with multiple meanings. Toronto's community food-security movement uses gardens as one strategy to regenerate the local food system and provide access to healthy, affordable food. Three garden case studies expand on the complexities of "food citizenship," illustrating the importance of that concept to notions of food security. The gardens reveal the role gardeners play in transforming urban spaces, the complex network of organizations working cooperatively and in partnership to implement these projects, and the way in which social and cultural pluralism are shaping the urban landscape. [source] Rethinking Caribbean transnational connections: conceptual itinerariesGLOBAL NETWORKS, Issue 1 2006D. ALISSA TROTZ At the same time, the intense focus on linkages between origin and destination groups frequently ends up privileging this binary - home/away - as the only way to map enduring cross-border linkages. Drawing on two examples of Caribbean practices connecting Toronto and New York, in this article I suggest the traversing of a different spatial terrain and consider the implications of expanding our conceptual itineraries to include these other journeys that so far have tended to fly under the radar in discussions of transnational migration. [source] Linking return visits and return migration among Commonwealth Eastern Caribbean migrants in TorontoGLOBAL NETWORKS, Issue 1 2004David Timothy Duval Return visits are periodic but temporary sojourns made by members of migrant communities to their external homeland or another location where strong social ties exist. As a result, the conceptual framework in this article revolves around transnationalism as the return visit is shown to be a transnational exercise that may facilitate return. Using data from ethnographic fieldwork, three themes highlight the link between return visits and return migration: (1) the need to facilitate ties such that relationships are meaningful upon permanent return; (2) the functional nature of the return visit, such that changes are measured and benchmarked against what is remembered and internalized by the migration after the migration episode; and (3) the knowledge that return visits aid in reintegration. [source] Reliability and construct validity of the compatible MRI scoring system for evaluation of elbows in haemophilic childrenHAEMOPHILIA, Issue 2 2008A. S. DORIA Summary., We assessed the reliability and construct validity of the Compatible MRI scale for evaluation of elbows, and compared the diagnostic performance of MRI and radiographs for assessment of these joints. Twenty-nine MR examinations of elbows from 27 boys with haemophilia A and B [age range, 5,17 years (mean, 11.5)] were independently read by four blinded radiologists on two occasions. Three centres participated in the study: (Toronto, n = 24 examinations; Atlanta, n = 3; Cuiaba, n = 2). The number of previous joint bleeds and severity of haemophilia were reference standard measures. The inter-reader reliability of MRI scores was substantial (ICC = 0.73) for the additive (A)-scale and excellent (ICC = 0.83) for the progressive (P)-scale. The intrareader reliability was excellent for both P-scores (ICC = 0.91) and A-scores (ICC = 0.93). The total P- and A-scores correlated poorly (r = 0.36) or moderately (r = 0.54), but positively, with clinical-laboratory measurements. The total MRI scores demonstrated high accuracy for discrimination of presence or absence of arthropathy [P-scale, area-under-the-curve (AUC) = 0.94 ± 0.05; A-scale, AUC = 0.89 ± 0.06], as did the soft tissue scores of both scales (P-scale, AUC = 0.90 ± 0.06; A-scale, AUC = 0.86 ± 0.06). Areas-under-the-curve used to discriminate severe disease demonstrated high accuracy for both P-MRI scores (AUC = 0.83 ± 0.09) and A-MRI scores (AUC = 0.87 ± 0.09), but non-diagnostic ability to discriminate mild disease. Similar results were noted for radiographic scales. In conclusion, both MRI scales demonstrated substantial to excellent reliability and accuracy for discrimination of presence/absence of arthropathy, and severe/non-severe disease, but poor to moderate convergent validity for total scores and non-diagnostic discriminant validity for mild/non-mild disease. Compared with radiographic scores, MRI scales did not perform better for discrimination of severity of arthropathy. [source] Lay understandings of the effects of poverty: a Canadian perspectiveHEALTH & SOCIAL CARE IN THE COMMUNITY, Issue 6 2005Linda I. Reutter RN PhD Abstract Although there is a large body of research dedicated to exploring public attributions for poverty, considerably less attention has been directed to public understandings about the effects of poverty. In this paper, we describe lay understandings of the effects of poverty and the factors that potentially influence these perceptions, using data from a telephone survey conducted in 2002 on a random sample (n = 1671) of adults from eight neighbourhoods in two large Canadian cities (Edmonton and Toronto). These data were supplemented with interview data obtained from 153 people living in these same neighbourhoods. Multivariate linear and logistic regressions were used to determine the effects of basic demographic variables, exposure to poverty and attribution for poverty on three dependent variables relating to the effects of poverty: participation in community life, the relationship between poverty and health and challenges facing low-income people. Ninety-one per cent of survey respondents agreed that poverty is linked to health, while 68% agreed that low-income people are less likely to participate in community life. Affordable housing was deemed especially difficult to obtain by 96%, but other resources (obtaining healthy food, giving children a good start in life, and engaging in healthy behaviours) were also viewed as challenging by at least 70% of respondents. The regression models revealed that when controlling for demographics, exposure to poverty explained some of the variance in recognising the effects of poverty. Media exposure positively influenced recognition of the poverty,health link, and attending formal talks was strongly related to understanding challenges of poverty. Attributions for poverty accounted for slightly more of the variance in the dependent variables. Specifically, structural and sociocultural attributions predicted greater recognition of the effects of poverty, in particular the challenges of poverty, while individualistic attributions predicted less recognition. Older and female respondents were more likely to acknowledge the effects of poverty. Income was positively associated with recognition of the poverty,health link, negatively associated with understanding the challenges of low-income people, and unrelated to perceptions of the negative effect of poverty on participation in community life. [source] Making Movies Matter or Whatever Happened to the Sabre-Tooth Curriculum?INTERNATIONAL JOURNAL OF ART & DESIGN EDUCATION, Issue 3 2001Cary Bazalgette This paper argues that media education has developed its own orthodoxies that are preventing it both from addressing the realities of the media as they exist today, and from being taken seriously by policy-makers. The example of Making Movies Matter, the 1999 report of the Film Education Working Group, shows how a policy-making ,window' can be exploited, not only to make new arguments for media education, but also to construct new frameworks for teaching and learning. The report had also provided the British Film Institute with a new agenda for UK-wide activities designed to develop education about the moving image media. A version of this paper was originally presented at the Summit 2000 conference in Toronto, Canada, in May 2000. [source] Community in Distress: Mental Health Needs and Help-seekingin the Tamil Community in TorontoINTERNATIONAL MIGRATION, Issue 5 2003Morton Beiser First page of article [source] Correlation between Braden Scale and Palliative Performance Scale in advanced illnessINTERNATIONAL WOUND JOURNAL, Issue 4 2008Vincent Maida Abstract This study describes the significant correlation between the Braden Scale (BS) and the Palliative Performance Scale (PPS) in patients with advanced illness that has not been previously reported. The analysis was based on a prospective sequential case series of 664 patients suffering from advanced illness who were referred to a regional palliative medicine programme in Toronto, Canada. Baseline BS and PPS scores assessed within 24 hours of referral were considered for analysis. After controlling for age, gender, consult site and diagnosis (cancer versus non cancer), we observed a significant positive correlation between baseline PPS and BS scores (r = 0·885, P < 0·001). These findings suggest that for patients with advanced illness where BS is not routinely used, PPS could be considered as a proxy for pressure ulcer risk assessment. [source] The Education-Contingent Association Between Religiosity and Health: The Differential Effects of Self-Esteem and the Sense of MasteryJOURNAL FOR THE SCIENTIFIC STUDY OF RELIGION, Issue 4 2008SCOTT SCHIEMAN Using data from a representative sample of adults in Toronto, Canada, I examine the education-contingent association between religiosity (subjective religiosity and religious attendance) and four health-related outcomes: depression, anxiety, alcohol use, and self-rated health. I also test the extent that two personal resources,the sense of mastery and self-esteem,contribute to those associations. Findings indicate that subjective religiosity and attendance are generally associated with lower levels of depression, anxiety, alcohol use, and poor health. Moreover, although not entirely uniform, subjective religiosity and attendance tend to be associated more negatively with these outcomes among individuals with fewer years of education. While the sense of mastery suppresses the education-contingent influence of religiosity on distress outcomes, self-esteem generally contributes to those patterns. On balance, the suppression effects of mastery are offset by the explanatory effects of self-esteem. These findings elaborate on the well-established association between religiosity and health by illustrating education-contingent effects and potential counterbalancing roles of personal resources in these processes. [source] Energy-Containing Nutritional Supplements Can Affect Usual Energy Intake Postsupplementation in Institutionalized Seniors with Probable Alzheimer's DiseaseJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 9 2006Matthew D. Parrott BSc OBJECTIVES: To determine whether increases in caloric intake associated with consumption of a mid-morning nutritional supplement for 3 weeks were maintained in the week after stopping the supplement and to investigate the effects of body mass index (BMI) and cognitive and behavioral measures on this response. DESIGN: Secondary analysis of a previously published randomized, crossover, nonblinded clinical trial. SETTING: A fully accredited geriatric care facility affiliated with the University of Toronto. PARTICIPANTS: Thirty institutionalized seniors with probable Alzheimer's disease (AD) who ate independently. MEASUREMENTS: Investigator-weighed food intake, body weight, cognitive (Severe Impairment Battery; Global Deterioration Scale) and behavioral (Neuropsychiatric Inventory,Nursing Home version; London Psychogeriatric Rating Scale) assessments. RESULTS: Individuals who responded successfully to supplementation as indicated by increases in daily energy intake were likely to maintain 58.8% of that increase postsupplementation, although stopping the supplement was associated with decreased habitual energy intake in low-BMI individuals who reduced their daily intakes during supplementation in response to the extra calories. Cognitive/behavioral tests were not reliable predictors of postsupplement intake. CONCLUSION: Institutionalized seniors with probable AD are likely to alter their usual energy intakes to maintain changes resulting from 3 weeks of supplementation. This effect may allow for rotating supplementation schedules in nursing homes that could reduce staff burden, but only for those individuals who are most likely to respond favorably. These data indicate that nutritional supplements and diet plans should be carefully prescribed in low-BMI individuals to limit variability in total energy provided and thus prevent lower-than-normal intake. [source] G-20 Summit (Toronto): Attempt to Reconcile DifferencesAFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 6 2010Article first published online: 3 AUG 2010 No abstract is available for this article. [source] Driving Vengeance and Willful Violations: Clustering of Problem Driving AttitudesJOURNAL OF APPLIED SOCIAL PSYCHOLOGY, Issue 1 2005Dwight A. Hennessy A total of 93 drivers (46 female, 47 male) from Toronto, Canada, with at least 5 years' driving experience, completed a battery of self-report questionnaires assessing the likelihood of engaging in mild driver aggression, frequency of past driver violence, driving vengeance, and willful violations. All were recruited as voluntary participants through posted signs, personal contact, and referrals. Mild driver aggression increased independently with elevated vengeance and elevated violations. Driver violence was predicted by the three-way interaction of Vengeance × Violations × Gender such that violence increased in male drivers with a vengeful attitude, especially in combination with higher levels of violations. The data indicated that driver aggression and violence were more prevalent among drivers who held clusters of other dangerous driving attitudes and behaviors as part of their typical behavior routine. [source] Cancer stem cells in leukemia, recent advancesJOURNAL OF CELLULAR PHYSIOLOGY, Issue 2 2007Gang-Ming Zou The history of stem cell research was started in the early 1900s in Europe where the researcher realized that various types of blood cells came from a particular "stem cells." However, it was not until 1963 that the first quantitative description of the self-renewal activities of transplanted mouse bone marrow cells were documented by Canadian scientist Ernest A McCulloch and James E Till in Toronto. The concept of cancer stem cells has been used over 50 years ago; whereas the strong evidence for the existence of a Cancer Stem Cells was obtained recently. Consequently, there is increasing attention in recent year about cancer stem cells. The findings from recent studies support the concept that stem cells are integral to the development of several forms of human cancer. Changes in stem cell behavior can contribute to tumor formation. Leukemia is a cancer of blood-forming tissue, including the bone marrow and lymphatic system. Leukemic stem cells represent the cancer stem cells in the leukemia. In this review, we summarize the recent advance in the study of leukemic stem cells. J. Cell. Physiol. 213: 440,444, 2007. © 2007 Wiley-Liss, Inc. [source] Methodology for evaluating physician order entry (POE) implementationsJOURNAL OF EVALUATION IN CLINICAL PRACTICE, Issue 4 2003Glen Geiger MD CM MASc BASc FRCPC Abstract The body of physician order entry (POE) implementations literature uses statistical evaluation methods to demonstrate changes in specified variables after POE implementation. To understand and manage the holistic impact of POE on the health care institution, a methodology that utilizes feedback to guide the POE implementation towards the satisfaction of stakeholder objectives is presented. Stakeholders jointly define quantitative and qualitative metrics for their objectives, establish target value vectors for the metrics that represent acceptable implementation outcomes and specify evaluation milestones. These are used to compare pre- and post-POE implementation clinical performance, enabling a socio-technical feedback,improvement cycle. A case study is provided to illustrate how the methodology is being used at Sunnybrook and Women's College Health Science Centre in Toronto, Canada. [source] An assessment of consumer preference for fair trade coffee in Toronto and VancouverAGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 2 2010John Cranfield In this article, the authors use conjoint analysis to elicit the views of coffee consumers on the attributes of Fair Trade coffee using data from the Greater Toronto Area and Vancouver collected through face-to-face interviews with consumers. The impact of socioeconomic and demographic factors on respondents' acceptance of Fair Trade coffee is evaluated using cluster analysis and multinomial logit models. The results suggest that, regardless of location, consumers place a strong premium on price and labeling claims. Three consumer segments are identified in each city; in Toronto, these segments are labeled Fair Trade-Focused, Price Conscious, and Balanced Buyers; for Vancouver these segments are labeled Organic and Fair Trade-Focused, Price Conscious, and Balanced Buyers. Although a broad spectrum of variables influences segment membership, no single variable explains membership in the same segment in each city. Such a result is rather telling; it suggests deeper constructs underlie segment membership, and presumably consumption behavior with respect to Fair Trade coffee. © 2010 Wiley Periodicals, Inc. [source] "Cultivating Children as You Would Valuable Plants:" The Gardening Governmentality of Child Saving, Toronto, Canada, 1880s,1920s1JOURNAL OF HISTORICAL SOCIOLOGY, Issue 4 2003Xiaobei Chen An analysis of gardening metaphors contributes to understanding mechanisms of bio-power on the site of child saving. This paper argues that the child saving movement attempted to install a mode of proper parental control that can be described as "the gardening governmentality", it was primarily positive/productive (yet without excluding repressive elements), individualized, intelligent, and localized. [source] Integrating pediatric hospitalists in the academic health science center: Practice and perceptions in a canadian center,,JOURNAL OF HOSPITAL MEDICINE, Issue 4 2010FRCPC, Sanjay Mahant MD Abstract BACKGROUND: The integration of hospitalists in academic settings has been identified as a challenge to the hospitalist movement. The Division of Pediatric Medicine, Hospital for Sick Children, Toronto, was established in 1981, providing a rich resource to examine this field in the academic context and inform academic program development. OBJECTIVES: To explore the characteristics, practice, perceptions, and contributions of pediatric hospital medicine in an academic health science center (AHSC). METHODS: A cross-sectional survey of physicians attending on the pediatric medicine inpatient unit (PMIU) (n = 20). RESULTS: Clinical activity included attending on the PMIU, consultation and comanagement outside the PMIU, and outpatient care of "hospital intense" patients. There was a high level of engagement in research, education, and quality improvement activities. Perceived advantages to a career as a hospitalist included: working in a team; generalist approach to care; stability relative to community practice; intellectually stimulating and rewarding work; and growing area for scholarship. Perceived disadvantages to a career as a hospitalist included: burnout; recognition and respect; and lack of long-term relationships with patients. Themes regarding barriers to establishing a career as a hospitalist in an AHSC were as follows: burnout; time and skills to develop an academic niche; balance between clinical and academic priorities; and system for career advancement. CONCLUSIONS: The contributions of pediatric hospitalists to the academic mission were diverse. Fellowship training, faculty development, and balance between time allocated to direct patient care and academic pursuits should be defined. This will help ensure career development, viability, and realization of excellence in the academic context. Journal of Hospital Medicine 2010;5:228,233. © 2010 Society of Hospital Medicine. [source] Interior Design at a Crossroads: Embracing Specificity through Process, Research, and Knowledge,JOURNAL OF INTERIOR DESIGN, Issue 3 2008Tiiu Poldma Ph.D. Tiiu Poldma is Vice Dean of Graduate Studies and Research in the Faculty of Environmental Design, and associate professor at the School of Industrial Design at the University of Montreal. Tiiu Poldma received a BID at Ryerson in 1982 (Toronto), MA in Culture and Values in Education in 1999 and Doctor of Philosophy in 2003, both from McGill University in Montreal, Canada. She teaches interior design studio and theory within the Bachelor of Interior Design program at the University of Montreal, and advanced research methodologies in the Masters of Science and Ph.D. programs at the Faculty of Environmental Design. She is currently the Director of the Research Group GRID(Group for Research in Illumination and Design) and heads up the Colour, Light and Form Lab (Laboratoire Forme*couleur*lumiere) at the faculty. She accredits design programs as a site evaluator for CIDAboth in Canada and the United States, and is also a member of the Editorial Board of Inderscience where she is the Regional Editor of the Journal of Design Research (JDR), and serves on the Editorial Board of Design/Science/Planning (Techne Press, Amsterdam). [source] Circulating soluble cytochrome c in liver disease as a marker of apoptosisJOURNAL OF INTERNAL MEDICINE, Issue 2 2003Z. Ben-Ari Abstract. Ben-Ari Z, Schmilovotz-Weiss H, Belinki A, Pappo O, Sulkes J, Neuman MG, Kaganovsky E, Kfir B, Tur-Kaspa R, Klein T (Beilinson and Golda Campuses, Rabin Medical Center, Petah Tiqva and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, and In Vitro Toxicology Laboratory, Sunnybrook Women's College, Toronto, Canada) Circulating soluble cytochrome c in liver disease as a marker of apoptosis. J Intern Med 2003; 254: 168,175. Objectives. To measure levels of soluble cytochrome c, a clinical marker of apoptosis in patients with liver disease; determine whether soluble cytochrome c is derived from the liver; and correlate soluble cytochrome c level with histology and disease activity. Design. Laboratory research study with comparison group. Setting. Liver Institute, at the Rabin Medical Center, Israel, and In Vitro Toxicology Laboratory, Canada. Subjects. A total of 108 patients with liver disease and 30 healthy controls. Interventions. Paired hepatic and portal vein samples were taken via the transjugular vein in patients after liver biopsy and transjugular intrahepatic portacaval shunt, and bile from patients with external biliary drainage. Soluble cytochrome c was measured with an enzyme-linked immunosorbent assay in peripheral blood. Apoptotic cells in liver tissue were identified by morphological criteria and quantitated with the dUTP nick-end-labelling (TUNEL) assay. Main outcome measures. Soluble cytochrome c level by type of liver disease by clinical and histological findings. Results. Soluble cytochrome c concentration (mean 187.1 ± 219.5 ng mL,1) was significantly higher in patients with liver disease than in controls (39.8 ± 35.1 ng mL,1; P = 0.0001), with highest levels in the primary sclerosing cholangitis group (mean 1041.0 ± 2844.8 ng mL,1; P = 0.001). Cytochrome c levels were correlated with serum bilirubin, alkaline phosphatase, creatinine levels, necroinflammatory score and apoptotic index, but not with serum alanine aminotransferase and synthetic liver function tests. In the 16 paired samples, soluble cytochrome c level was higher in the hepatic (mean 267.9 ± 297.0 ng mL,1) than the portal vein (mean 169.2 ± 143.3 ng mL,1), and it was highly detectable in bile (mean 2288.0 ±4596.0 ng mL,1) (P = 0.001). Untreated patients with chronic viral hepatitis (B and C) had significantly higher levels (mean 282.8 ±304.3 ng mL,1) than treated patients (77.9 ± 35.8 ng mL,1; P = 0.001). Conclusions. Soluble cytochrome c levels are increased in different types of liver disease. Soluble cytochrome c is probably derived from the liver and secreted into the bile. Levels correlate with the apoptotic index and are affected by antiviral treatment. Soluble cytochrome c may serve as a serum marker of apoptosis. [source] 'You're So Fat!': Exploring Ojibwe DiscourseJOURNAL OF LINGUISTIC ANTHROPOLOGY, Issue 2 2001Linda C. Garro 'You're So Fat!': Exploring Ojibwe Discourse. Roger Spielmann. Toronto, Buffalo, and London: University of Toronto Press, 1998. xi. 280 pp. [source] | ||||||||||||||||||||||||||||||||||||||||||||||