To

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of To

  • aim. to
  • aims. to
  • due to
  • h. to
  • in order to
  • letter to
  • order to
  • up to

  • Terms modified by To

  • to day
  • to face
  • to face interview
  • to review
  • to study
  • to test

  • Selected Abstracts


    Moments of phonon density of states spectra and characteristic phonon temperatures of wide band gap materials

    PHYSICA STATUS SOLIDI (B) BASIC SOLID STATE PHYSICS, Issue 12 2006
    Roland Pässler
    Abstract We have re-digitized a variety of phonon density of states (PDOS) spectra, that have been published by different researchers for the wide band gap materials diamond, SiC, BN, AlN, GaN, ZnO, ZnS, and ZnSe, including calculations of the respective first- and second-order moments. Notwithstanding the obvious differences in concrete shapes of spectra presented for one and the same material by different authors, the respective magnitudes of estimated moments have been found in most cases to be nearly the same (to within uncertainties of some few%). Anticipated differences between phonon temperatures, ,eff, that are effective in controlling the observable temperature dependences of fundamental energy gaps and the respective average phonon temperatures, ,P, are seen to be throughout smaller than ±10%. The estimated high-temperature limits of Debye temperatures, ,D(,), are found to be significantly higher (by factors of order 1.4) than ,P. As a remarkable heuristic finding revealed by our numerical and analytical studies we can further state that, for SiC, AlN, GaN, ZnO, ZnS, and ZnSe, the individual ,D(,) values are nearly equal (within ±5%) to the respective average optical (LO/TO) phonon temperatures pertaining to the upper sections of the corresponding PDOS spectra. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]


    [Commentary] FINANCIAL STRESS AND SMOKING CESSATION,A SILVER LINING TO THE DARK CLOUDS OF THE GLOBAL ECONOMY?

    ADDICTION, Issue 8 2009
    FRANK J. CHALOUPKA
    No abstract is available for this article. [source]


    Analysis of chicken and turkey ovalbumins by microchip electrophoresis combined with exoglycosidase digestion

    ELECTROPHORESIS, Issue 18 2003
    Xiuli Mao
    Abstract The polypeptide and carbohydrate patterns of two glycoproteins, chicken ovalbumin (CO) and turkey ovalbumin (TO), were analyzed by microchip electrophoresis (ME), following digestion with proteases and exoglycosidases. Glycopeptides derived from ovalbumin were obtained by digestion with Pronase, followed by dialysis, and then separated by ME. Using CO as model, the method was developed to deduce the structure of glycans from glycoproteins by comparing the electropherograms of glycopeptides with and without digestion of exolycosidases. Applying the same approach, the structure of oligosaccharides linked to TO was determined. TO was found to contain high-mannose type oligosaccharides and oligosaccharides with terminal N -acetylglucosamine residues. The complete primary analysis of CO and TO by ME described in this paper provides a basis for an analysis of glycoproteins with an integrated microfluidic chip. [source]


    [Commentary] POOR MEXICO: SO FAR AWAY FROM GOD, SO CLOSE TO THE UNITED STATES

    ADDICTION, Issue 4 2009
    RAUL CAETANO
    No abstract is available for this article. [source]


    [Commentary] REGRESSION TO THE MEAN IN ADDICTION RESEARCH

    ADDICTION, Issue 1 2008
    ROBERT L. STOUT
    No abstract is available for this article. [source]


    An Approach to the Synthesis of Silicon Carbide Nanowires by Simple Thermal Evaporation of Ferrocene onto Silicon Wafers

    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 25 2007
    Jun-Jie Niu
    Abstract Scales of silicon carbide nanowires (SiC-NWs) with high quality were synthesized by direct thermal evaporation of ferrocene onto silicon wafers at high temperature. Ferrocene decomposed into iron and carbon, which was subsequently treated with silicon to form SiC-NWs at high temperature. The SiC-NWs possess small diameters of , 20 nm and lengths of several ,ms. Furthermore, the samples show a uniform morphology, crystalline structure, and a very thin oxide layer. The main crystal direction of [111] was confirmed by high-resolution field-emission-transmission electron microscopy (HR-FETEM). The Raman scattering spectra showed two peaks at , 796 (TO) and , 980 cm,1 (LO) with varying intensity ratios at different positions. The band line fluctuation was contributed to the Raman selection rules. With reference to the experimental results, we suggested a tentative growth model according to the vapor,liquid,solid (VLS) mechanism. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source]


    Intercalating Dye Harnessed Cationic Conjugated Polymer for Real-Time Naked-Eye Recognition of Double-Stranded DNA in Serum

    ADVANCED FUNCTIONAL MATERIALS, Issue 9 2009
    Kan-Yi Pu
    Abstract Thiazole orange (TO), an intercalating dye, is integrated into cationic poly(fluorene- alt -phenylene) (PFP) to develop a macromolecular multicolor probe (PFPTO) for double-stranded DNA (dsDNA) detection. This polymer design not only takes advantage of the high affinity between TO and dsDNA to realize dsDNA recognition in biological media, but also brings into play the light-harvesting feature of conjugated polymers to amplify the signal output of TO in situ. PFPTO differentiates dsDNA from single-stranded DNA (ssDNA) more effectively upon excitation of the conjugated backbone relative to that upon direct excitation of TO as a result of efficient fluorescence resonance energy transfer from the polymer backbone to the intercalated TO. In the presence of dsDNA, energy transfer within PFPTO is more efficient as compared to that for free TO/PFP system, which leads to better dsDNA discriminability for PFPTO in contrast to that for TO/PFP. The distinguishable fluorescent color for PFPTO solutions in the presence of dsDNA allows naked-eye detection of dsDNA with the assistance of a hand-held UV lamp. The significant advantage of this macromolecular fluorescent probe is that naked-eye detection of label-free dsDNA can be performed in biological media in real-time. [source]


    LETTER TO THE EDITOR: A novel homozygous point mutation at codon 82 (HBB:c.247A > T) in the beta-globin gene leads to thalassemia major

    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, Issue 5 2010
    R. Angalena
    No abstract is available for this article. [source]


    Flow cytometric method for simultaneous assay of foetal haemoglobin containing red cells, reticulocytes and foetal haemoglobin containing reticulocytes

    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, Issue 3 2001
    Y. Mundee
    Level of foetal haemoglobin (HbF) containing red cells (F cells) is a parameter for monitoring sickle cell anaemia (SS) patients undergoing treatment with HbF modulating drugs (including hydroxyurea (HU)). One convenient technique for F cell assay is flow cytometry. A flow cytometric method for the simultaneous assay of F cells, reticulocytes and HbF-containing reticulocytes (F reticulocytes) is described in this paper. These three parameters can be obtained within 2 h using double colour staining flow cytometry. Glutaraldehyde fixation, Triton X-100 permeabilization, monoclonal antibody to HbF Tri-colour® conjugate (MoAb-HbF-TC; deep-red fluorescence) immuno-staining and thiazole orange (TO; green fluorescence) are employed. The red cell gate was set on forward scatter (FSC) and logarithmic side scatter (logSSC) for 50 000 cells on the flow cytometer. Fluorescent signals were acquired from fluorescent channel 1 (FL1; green) and (FL4; deep-red). Coefficient of variation percent (%CVs) of intra- and inter-assay were less than 9% and 15%, respectively. EDTA, citrate, heparin and CTAD anticoagulants are all suitable; the samples can be stored at 4°C for up to 6 days. The method is a simple, rapid, convenient, reproducible and useful way of determining F cell, reticulocyte and F reticulocyte levels in sickle cell and thalassaemic patients. [source]


    Ab initio quantum-mechanical prediction of the IR and Raman spectra of Ca3Cr2Si3O12 Uvarovite garnet

    INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, Issue 2 2010
    L. Valenzano
    Abstract The IR and Raman spectra of uvarovite (Ca3Cr2Si3O12) garnet were simulated with the periodic ab initio CRYSTAL code by adopting an all-electron Gaussian-type basis set and the B3LYP Hamiltonian. The two sets of 17 F1u Transverse-Optical (TO) and Longitudinal-Optical (LO) frequencies are generated, together with their intensities. As regards the IR experimental spectrum, only five peaks are available, that are in excellent agreement with the calculated data (mean absolute difference smaller than 5.2 cm,1). The analysis of the TO-LO eigenvalue overlaps permits to establish a correspondence between LO and TO modes. The set of experimental Raman peaks is much reacher (23 out of 25) and the agreement with our calculations excellent ( smaller than 6 cm,1). Isotopic substitution is used to identify the zones of the spectrum where Cr and Ca contributions are relevant. © 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2010 [source]


    Novel Measures of Heart Rate Variability Predict Cardiovascular Mortality in Older Adults Independent of Traditional Cardiovascular Risk Factors: The Cardiovascular Health Study (CHS)

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 11 2008
    PHYLLIS K. STEIN Ph.D.
    Background: It is unknown whether abnormal heart rate turbulence (HRT) and abnormal fractal properties of heart rate variability identify older adults at increased risk of cardiovascular death (CVdth). Methods: Data from 1,172 community-dwelling adults, ages 72 ± 5 (65,93) years, who participated in the Cardiovascular Health Study (CHS), a study of risk factors for CV disease in people ,65 years. HRT and the short-term fractal scaling exponent (DFA1) derived from 24-hour Holter recordings. HRT categorized as: normal (turbulence slope [TS] and turbulence onset [TO] normal) or abnormal (TS and/or TO abnormal). DFA1 categorized as low (,1) or high (>1). Cox regression analyses stratified by Framingham Risk Score (FRS) strata (low = <10, mid = 10,20, and high >20) and adjusted for prevalent clinical cardiovascular disease (CVD), diabetes, and quartiles of ventricular premature beat counts (VPCs). Results: CVdths (N = 172) occurred over a median follow-up of 12.3 years. Within each FRS stratum, low DFA1 + abnormal HRT predicted risk of CVdth (RR = 7.7 for low FRS; 3.6, mid FRS; 2.8, high FRS). Among high FRS stratum participants, low DFA1 alone also predicted CVdth (RR = 2.0). VPCs in the highest quartile predicted CVdth, but only in the high FRS group. Clinical CV disease predicted CVdth at each FRS stratum (RR = 2.9, low; 2.6, mid; and 1.9, high). Diabetes predicted CVdth in the highest FRS group only (RR = 2.2). Conclusions: The combination of low DFA1 + abnormal HRT is a strong risk factor for CVdth among older adults even after adjustment for conventional CVD risk measures and the presence of CVD. [source]


    Relationship Between Heart Rate Turbulence and Heart Rate, Heart Rate Variability, and Number of Ventricular Premature Beats in Coronary Patients

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 7 2004
    IWONA CYGANKIEWICZ M.D., Ph.D.
    Introduction: Heart rate variability (HRV) illustrates regulation of the heart by the autonomic nervous system whereas heart rate turbulence (HRT) is believed to reflect baroreflex sensitivity. The aim of this study was to determine the association between HRT and HRV parameters and the relationship between HRT parameters and heart rate and number of ventricular premature beats (VPBs) used to calculate HRT parameters. Methods and Results: In 146 patients (117 males and 29 females; mean age 62 years) with coronary artery disease, a 24-hour ECG Holter monitoring was performed to calculate mean heart rate (RR interval), number of VPBs, time- and frequency-domain HRV parameters and two HRT parameters: turbulence onset (TO) and turbulence slope (TS). Univariate and multivariate regression analyses were performed to evaluate the association between tested parameters. Significant correlation between TS and mean RR interval was observed (r = 0.42; p < 0.001), while no association for TO vs. RR interval was found. TS values were significantly higher in patients with less than 10 VPBs/24 hours than in patients with more frequent VPBs. Significant associations between HRT and HRV parameters were found with TS showing stronger correlation with HRV parameters than TO (r value ranging from 0.35 to 0.62 for TS vs. ,0.16 to ,0.38 for TO). Conclusion: HRT parameters correlate strongly with HRV parameters indicating that HRT should be considered as a reflection of both baroreceptors response and overall autonomic tone. Heart rate dependence of turbulence slope indicates the need to adjust this parameter for heart rate. (J Cardiovasc Electrophysiol, Vol. 15, pp. 731-737, July 2004) [source]


    Size-dependent Raman and infrared studies of PbSe nanoparticles

    JOURNAL OF RAMAN SPECTROSCOPY, Issue 9 2008
    F. S. Manciu
    Abstract Micro-probe Raman and far-infrared absorption spectroscopies were used to prove the existence of optical phonon modes of PbSe nanoparticles prepared by colloidal chemistry and preliminarily characterized by transmission electron microscopy. To the best of our knowledge, this is the first time that evidence of the surface phonon (SP) mode by Raman spectroscopy has been experimentally observed. The wavenumber of the SP mode is consistent with its prediction by a dielectric continuum model. While for different PbSe nanoparticle sizes the observed SP mode does not show any obvious change in its position, there is a clear shift by approximately 4 cm,1 toward higher wavenumber in the appearance of the LO(,) in the Raman spectra from the 3 nm to the 7 nm PbSe nanoparticles. Far-infrared measurements demonstrate the presence of the transverse optical TO(,) and of the coupled phonon modes. Copyright © 2008 John Wiley & Sons, Ltd. [source]


    Raman studies of cubic BC2N, a new superhard phase

    JOURNAL OF RAMAN SPECTROSCOPY, Issue 10 2004
    H. W. Hubble
    Abstract UV and visible Raman scattering spectra of a new superhard phase, cubic BC2N, were measured for the first time. The Raman band at 1326 cm,1 was attributed to the longitudinal optical (LO) mode of cubic BC2N, whereas the transverse optic (TO) mode is missing in the spectra. Raman scattering was found to be a sensitive method for detecting new diamond-like BCN phases. Copyright © 2004 John Wiley & Sons, Ltd. [source]


    Fatty acid composition and volatile compounds of selected marine oils and meals

    JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 1 2009
    Ioannis Giogios
    Abstract BACKGROUND: Although volatile compounds characterising seafood have been studied extensively, no similar data are available regarding the volatiles of raw materials used in fish feed. Therefore the aim of this study was to make an initial screening of the volatiles of various common marine raw materials used in the aquaculture feed industry. Nine commercial marine oils (German (GFO1, GFO2 and GFO3) and Norwegian (NFO) fish oils and salmon (SO1 and SO2), tuna (TO), sardine (SRDO) and shrimp (SHO) oils) and eight commercial marine meals (Peruvian (PFM1 and PFM2), Danish (DFM1 and DFM2) and prime quality (PQFM1 and PQFM2) fish meals and Antarctic krill meals (KM1 and KM2)) were analysed for their fatty acid profiles and volatile flavour compounds. The relation between fatty acids and volatiles was examined. RESULTS: The highest polyunsaturated fatty acid and eicosapentaenoic acid (20:5,3) contents and ,3/,6 ratio were found in NFO. The fatty acid composition of all marine meals except krill meals was found to be more variable among batches than that of marine oils. Regarding volatiles, all marine raw materials were characterised by the complete absence or negligible levels of eight- and nine-carbon alcohols and carbonyls. All marine oils were found to have high 2-ethyl furan, 2-methylenebutyl cyclopropane, hexanal, 2,4-octadiene and 3,5-octadiene contents. Marine meals, unlike marine oils, were characterised by the almost complete absence of unsaturated and cyclic hydrocarbons and terpenes and very low levels of furans. CONCLUSION: Volatiles of marine meals differ from those of marine oils. Unlike fatty acids which give useful traceability information, volatiles seem to fail in this role owing to their strong variability. Copyright © 2008 Society of Chemical Industry [source]


    LETTERS TO THE EDITOR: Association between deep vein thrombosis and transient inflammatory signs and symptoms: a case,control study

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 8 2010
    Y. I. G. V. TICHELAAR
    No abstract is available for this article. [source]


    LETTERS TO THE EDITOR: Fondaparinux as an alternative anticoagulant therapy during pregnancy

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 8 2010
    H. M. KNOL
    First page of article [source]


    LETTERS TO THE EDITOR: High rates of symptomatic and incidental thromboembolic events in gastrointestinal cancer patients

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 8 2010
    R. SINGH
    No abstract is available for this article. [source]


    LETTER TO THE EDITOR: P2Y1 gene polymorphism and ADP-induced platelet response

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2005
    P. FONTANA
    No abstract is available for this article. [source]


    LETTERS TO THE EDITOR: Inhibition of thrombin activatable fibrinolysis inhibitor augments fibrinolysis in human whole blood

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2005
    N. L. M. CRUDEN
    No abstract is available for this article. [source]


    LETTERS TO THE EDITOR: Postoperative pericardial effusion in patients receiving anticoagulants for deep vein thrombosis after coronary artery bypass graft surgery

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2005
    M. AMBROSETTI
    No abstract is available for this article. [source]


    LETTERS TO THE EDITOR: More on: intensity of warfarin anticoagulation in APS

    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2005
    N. S. KEY
    No abstract is available for this article. [source]


    IN DEFERENCE TO THE OTHER: LONERGAN AND CONTEMPORARY CONTINENTAL THOUGHT, edited by Jim Kanaris and Mark J. Doorley

    NEW BLACKFRIARS, Issue 1012 2006
    PETER GROVES
    First page of article [source]


    Heart Rate Turbulence Impairment and Ventricular Arrhythmias in Patients with Systemic Sclerosis

    PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 8 2010
    PIOTR BIENIAS M.D., Ph.D.
    Background:,Arrhythmias, conduction disturbances, and cardiac autonomic nervous system dysfunction are the most frequent cardiovascular complications in systemic sclerosis (scleroderma). The aim of the study was to assess heart rate turbulence (HRT) in systemic sclerosis patients and to identify the relationship between HRT and occurrence of arrhythmias. Methods:,Forty-five patients with scleroderma (aged 54.6 ± 14.7 years) and 30 healthy sex- and age-matched subjects were examined. In addition to routine studies, 24-hour Holter monitoring with assessment of HRT was performed. Results:,As compared to controls, HRT was significantly impaired in systemic sclerosis patients. Abnormal HRT defined as turbulence onset (TO) ,0.0% and/or turbulence slope (TS) ,2.5 ms/RR (ms/RR interval) was found in 19 (42%) scleroderma patients and in no members of the control group. Serious ventricular arrhythmias Lown class IV (VA-LownIV), for example, couplets and/or nonsustained ventricular tachycardias, were observed in 16 (36%) scleroderma patients. The median value of TS was significantly lower in systemic sclerosis patients with VA-LownIV than in patients without VA-LownIV (3.68 vs 7.00 ms/RR, P = 0.02). The area under curve of ROC analysis for prediction of VA-LownIV was 0.72 (95% confidence interval [CI] 0.56,0.87) and revealed that TS <9.0 ms/RR was associated with VA-Lown IV occurrence, with sensitivity of 93.7% and specificity of 44.8%. Univariate and multivariate analyses confirmed that lower values of TS were associated with VA-LownIV occurrence (odds ratio 1.52, 95% CI 1.09,2.12, P = 0.01). Conclusions:,Patients with systemic sclerosis are characterized by significant HRT impairment. Assessment of HRT and especially TS is useful in the identification of patients at risk for ventricular arrhythmias. (PACE 2010; 920,928) [source]


    Heart Rate Turbulence After Short Runs of Nonsustained Ventricular Tachycardia in Chronic Heart Failure

    PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 6 2007
    PANAYOTA FLEVARI M.D.
    Background:Heart rate turbulence (HRT) following isolated premature complexes is a baroreceptor-mediated prognostic marker. Short runs of spontaneous, nonsustained ventricular tachycardia (nsVT) exert a greater hemodynamic effect than extrasystoles and may trigger a more potent turbulence-like response (HRTVT), possibly related to other risk-related markers, such as heart rate variability (HRV), left ventricular ejection fraction (EF), and original HRT parameters (turbulence slope [TS] and turbulence onset [TO]). Methods:We studied 27 patients with heart failure (HF) and nsVT (4,7 beats) on 24-hour Holter electrocardiographic recordings (mean age 58 ± 3.6 years, EF 36%± 5.0%). Following nsVT, TSVT and TOVT were measured according to the original definitions. HRV, TS, and TO were also assessed. Results:HRTVT parameters were related to HRV. A significant relation existed between TSVT and EF (r= 0.66, P < 0.05). HRTVT parameters were related to the originally described (TS and TO), whereas TOVT was higher than TO (1.63 ± 1.6 vs ,1.7 ± 0.65, P < 0.05). Conclusions:In mild-to-moderate HF, turbulence is observed following short nsVT runs and is related to prognostically important HRV indexes and EF. HRTVT is similar to HRT but TOVT is shifted toward more positive values than TO. HRTVT might be prognostically significant. [source]


    The effect of fetal tracheal occlusion on lung tissue mechanics and tissue composition,

    PEDIATRIC PULMONOLOGY, Issue 2 2009
    Jacques C. Jani MD
    Abstract Fetal tracheal occlusion (TO) is currently used to treat severe cases of congenital diaphragmatic hernia (DH). Clinical and experimental studies suggest an improved postnatal outcome, but lung tissue mechanics after TO have not been studied. We determined the effect of TO on mechanical impedance and lung tissue components in a rabbit model for DH. At 23 days of gestation (term,=,31 days) either a sham thoracotomy or a diaphragmatic defect was induced. DH fetuses were randomly assigned to undergo 5 days later TO. Fetuses were delivered by term cesarean section to determine lung to body weight ratio (LBWR), dynamic lung mechanics and lung impedance. Airway resistance (Raw), elastance (HL), tissue damping (GL) and hysteresivity (GL/HL) were calculated from impedance data. Collagen I and III and elastin were quantified histologically. LBWR was significantly increased by TO compared to DH (P,<,0.001) and resistance and compliance of the respiratory system (Rrs, Crs) were improved as well. TO resulted in a significant decrease of Raw comparable to observations in sham-fetuses, without effect on lung tissue mechanics HL, GL and hysteresivity. This coincides with a significant decrease of collagen I, III and elastin in comparison to DH fetuses. In this first report on lung tissue mechanics in a rabbit model of DH, TO had a substantial effect on tissue morphology yet this was not mirrored in lung mechanics. We conclude that the effect of TO on lung mechanics without in utero reversal of occlusion, is dominated by airway remodeling. Pediatr Pulmonol. 2009; 44:112,121. © 2009 Wiley-Liss, Inc. [source]


    Tracheobronchopathia Osteochondroplastica in a 9-year-old Girl

    PEDIATRIC PULMONOLOGY, Issue 1 2006
    Pelin Ozlem Simsek MD
    Abstract Tracheobroncopathia osteochondroplastica (TO) is a rare disease of adult males characterized by osteocartilagious submucosal nodules protruding into the airway lumen, causing variable degrees of airway obstruction. Here we describe a case of TO in a 9-year-old girl patient presenting with chronic cough, along with a brief review of this rare benign condition. Pediatr Pulmonol. © 2005 Wiley-Liss, Inc. [source]


    Stimulation of lung growth in fetuses with lung hypoplasia leads to altered postnatal lung structure in sheep

    PEDIATRIC PULMONOLOGY, Issue 4 2001
    M.G. Davey PhD
    Abstract Increased lung expansion in the fetus stimulates lung growth and is being trialed clinically to reverse severe fetal lung hypoplasia. Our aim was to examine the effects of increased fetal lung expansion in the presence of lung hypoplasia on lung structure in sheep at term and 8 weeks after birth. Lung hypoplasia was induced in 15 fetal sheep by continuous drainage of tracheal fluid, commencing at ,113 days of gestation (term, ,148 days). In 10 of these fetuses, tracheal obstruction (TO) was performed from 137,147 days of gestation (treated lung hypoplasia, TLH), while lung liquid drainage continued until term in the remaining 5 fetuses (untreated lung hypoplasia, ULH). Lung tissues were obtained from 5 TLH, 5 ULH, and 5 control lambs at birth, and from 5 TLH and 5 control lambs at 8 weeks after birth. At birth, alveolar number, surface area, and interalveolar wall thickness were not different between TLH and control lambs, whereas airspace diameter was greater in TLH lambs (72.7,±,3.0 ,m) than in controls (58.4,±,4.3 ,m). Diameters of airspaces were not different between ULH and control lambs; however, alveolar numbers and surface area were reduced, while interalveolar wall thickness was increased in ULH lambs compared to controls. At 8 weeks after birth, alveolar number (928.0,±,66.1,×,106) and surface area (30.3,±,2.2 m2) in TLH lambs were lower, whereas interalveolar wall thickness (83.0,±,3.1,m) was greater than in control lambs (2,263.6,±,261.6,×,106, 46.7,±,4.8 m2, and 68.6,±,2.1 ,m, respectively). Our data show that TO restores most aspects of lung structure to normal in fetuses with lung hypoplasia but leads to altered alveolar development. The presence of fewer, larger alveoli in postnatal TLH animals may predispose these animals to respiratory complications during later life. Pediatr Pulmonol. 2001; 32:267,276. © 2001 Wiley-Liss, Inc. [source]


    Structural order on different length scales in amorphous silicon investigated by Raman spectroscopy

    PHYSICA STATUS SOLIDI (A) APPLICATIONS AND MATERIALS SCIENCE, Issue 3 2010
    S. Muthmann
    Abstract Parameters for the structural short (SRO) and medium range order (MRO) of hydrogenated amorphous silicon (a-Si:H) films on the edge of the microcrystalline silicon (µc-Si:H) phase transition were studied with Raman spectroscopy. The observed samples were deposited using radio frequency plasma enhanced chemical vapor deposition. The studied films were grown with various constant and non-constant silane concentrations (SCs). A substrate dependent correlation of SC to the intensity ratio (IMRO) of the transversal acoustical (TA) and the transversal optical (TO) phonon bands was found. A strong correlation between width and position of the (TO) phonon band was observed. These two easily accessible parameters show an increase of SRO when IMRO decreases. [source]


    Resonant Raman scattering in spherical quantum dots: II,VI versus III,V semiconductor nanocrystals

    PHYSICA STATUS SOLIDI (B) BASIC SOLID STATE PHYSICS, Issue 6 2010
    Mikhail I. Vasilevskiy
    Abstract Resonant Raman scattering (RRS) in nearly-spherical nanocrystal (NC) quantum dots (QDs) is discussed with respect to the underlying (Fröhlich-type and optical deformation potential, ODP) mechanisms of the exciton,phonon interaction. Their relative contribution for different QD materials, both II,VI and III,V is compared. It is shown that the (usually overlooked) ODP interaction is entirely responsible for an additional peak in the RRS spectra, situated near the transverse-optical (TO) phonon frequency, which has been observed for InP, InAs and, recently, CdTe QDs. RRS spectra calculated using continuum models for confined phonons and excitons and taking into account both interaction mechanisms are in excellent agreement with these experimental data. [source]