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Tissue Cores (tissue + core)

Distribution by Scientific Domains

Medical Sciences	57%
Life Sciences	42%

Selected Abstracts

The structural design of the bat wing web and its possible role in gas exchange

JOURNAL OF ANATOMY, Issue 6 2007
Andrew N. Makanya
Abstract The structure of the skin in the epauletted fruit bat (Epomophorus wahlbergi) wing and body trunk was studied with a view to understanding possible adaptations for gas metabolism and thermoregulation. In addition, gas exchange measurements were performed using a respirometer designed for the purpose. The body skin had an epidermis, a dermis with hair follicles and sweat glands and a fat-laden hypodermis. In contrast, the wing web skin was made up of a thin bilayered epidermis separated by a connective tissue core with collagen and elastic fibres and was devoid of hair follicles and sweat glands. The wings spanned 18,24 cm each, with about 753 cm2 of surface exposed to air. The body skin epidermis was thick (61 ± 3 µm, SEM), the stratum corneum alone taking a third of it (21 ± 3 µm). In contrast, the wing web skin epidermis was thinner at 9.8 ± 0.7 µm, with a stratum corneum measuring 4.1 ± 0.3 µm (41%). The wing capillaries in the wing web skin ran in the middle of the connective tissue core, with a resultant surface-capillary diffusion distance of 26.8 ± 3.2 µm. The rate of oxygen consumption (V,O2) of the wings alone and of the whole animal measured under light anaesthesia at ambient temperatures of 24 ºC and 33 ºC, averaged 6% and 10% of the total, respectively. Rate of carbon dioxide production had similar values. The membrane diffusing capacity for the wing web was estimated to be 0.019 ml O2 min,1 mmHg,1. We conclude that in Epomophorus wahlbergi, the wing web has structural modifications that permit a substantial contribution to the total gas exchange. [source]

Light and Scanning Electron Microscopic Study on the Tongue and Lingual Papillae of the Common Hippopotamus, Hippopotamus amphibius amphibius

THE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 7 2009
Ken Yoshimura
Scanning electron microscopic micrograph of the connective tissue core of fungiform papillae distributed in the dorsal surface of the tongue in the common hippopotamus (Hippopotamus amphibius amphibius). There are various kinds of lingual papillae distributed on the dorsal surface of the tongue among mammal species. It has been revealed that there were morphological differences found on each lingual papilla; filiform, fungiform, conical, foliate, and vallate papillae depend on the mammalian species, especially on the connective tissue cores beneath the epithelial surface. The fungiform connective tissue core of hippopotamus exhibited are quite similar to those found in the other artiodactyls; however, it lacked other typical morphological types of the lingual papillae found on the artiodactyl species. The unique mosaic-like morphological characteristics of the hippopotamus' lingual papillae may represent the unique evolutional or dietary background of this species. See Yoshimura et al., on page 921, in this issue. (Scanning electron micrograph courtesy of the authors). [source]

Simple modification to the punch biopsy technique to minimize handling and crush artefact

AUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 4 2005
Alexander J Chamberlain
SUMMARY A number of techniques have been described to retrieve the tissue core after punch biopsy. We describe a simple modification to the punch-biopsy technique that minimizes instrumentation, handling and the subsequent risk of crush artefact. Our technique is simple, quick and economical and essentially involves rotation of the punch through 90° then lateral extraction with a degree of upward traction, which usually leaves the tissue core deposited beside the skin defect. At this point it can be easily grasped with a square of gauze or detached if required using scissors or a scalpel blade. [source]

Alteration of subcellular and cellular expression patterns of cyclin B1 in renal cell carcinoma is significantly related to clinical progression and survival of patients

INTERNATIONAL JOURNAL OF CANCER, Issue 4 2006
Stephen O. Ikuerowo
Abstract Cyclin B1, identified as a regulator of late cell cycle, is involved in the development and progression of a variety of human malignancies. To clarify the role of cyclin B1 in the pathogenesis and prognosis of renal cell carcinoma (RCC), protein expression was compared with clinicopathological characteristics of patients as well as the long-term survival after surgical therapy. Expression analysis was carried out by immunohistochemistry and tissue microarray analysis. The microarrays that represented the primary tumors, their invasion front and normal peritumoral renal parenchyma contained 753 tissue cores obtained from 251 randomly selected nephrectomy specimens. Immunopositivity within the primary tumors was significantly associated with tumor stage (pT) (p < 0.01), lymph node status (pN) (p < 0.01) as well as the presence of systemic metastatic disease (p = 0.01). Subcellular expression in the cytoplasm of tumor cells significantly correlated with pT (p = 0.02) and pN (p = 0.03). When peritumoral tissue samples exhibited a relative amount of <10% of positively reacting epithelial cells, cyclin B positivity was identified to predict long-term survival of patients in univariate analysis (p < 0.01) whereas borderline significance was observed in multivariate statistical analysis (p = 0.05). Increased intratumoral cyclin B1 positivity and aberrant localization of signals within the cytoplasm of tumor cells is positively correlated with the tendency towards tumor progression, indicating the significant role of cyclin B1 in the development and pathogenesis of RCC. The result of uni- and multivariate statistical analysis suggests the prognostic value of cyclin B1 for RCC patients. © 2006 Wiley-Liss, Inc. [source]

Light and Scanning Electron Microscopic Study on the Tongue and Lingual Papillae of the Common Hippopotamus, Hippopotamus amphibius amphibius

Yield of Terminal Duct Lobule Units in Normal Breast Stereotactic Core Biopsy Specimens: Implications for Biomarker Studies

THE BREAST JOURNAL, Issue 4 2000
Samina Mansoor MD
Abstract: The purpose of this study was to assess the potential value of large-needle core biopsies of normal breast tissue for immunohistochemical studies of epithelial risk assessment. A retrospective analysis was performed to determine the yield of nonatrophic terminal duct lobule units (TDLUs) in 11-gauge vacuum-assisted core biopsies of normal adjacent breast tissue which were included in routine stereotactic core biopsies of benign lesions. Fifty-one patients had a median of two normal tissue cores (range 1,7); 82% of the patients had two or more normal tissue cores; 47% had three or more normal tissue cores. Nonatrophic TDLUs were present in only 47% of patients and in 31% (42 of 137) of all cores. Patients with heterogeneous or dense normal mammographic parenchyma at the site of the biopsy were more likely to have nonatrophic TDLUs, 45% (20 of 44), than patients with fatty normal mammographic parenchyma at the biopsy site, 0% (0 of 7), p = 0.007. Seventy percent (7 of 10) of postmenopausal women on hormone replacement therapy had nonatrophic TDLUs as compared to 41% (11 of 27) of premenopausal and postmenopausal women not on hormones (p = not significant). Eleven-gauge vacuum-assisted core biopsies of normal breast tissue have a low yield of nonatrophic TDLUs suitable for histochemical studies of epithelial risk assessment. [source]

Bovine-HA spongiosa blocks and immediate implant placement in sinus augmentation procedures

CLINICAL ORAL IMPLANTS RESEARCH, Issue 4 2002
Histopathological, histomorphometric observations on different histological stainings in 10 consecutive patients
Abstract: Bovine mineral spongiosa block (B-SB) was used as a bone substitute in sinus augmentation procedures in 10 consecutive patients. Implants were placed during the same session. The purpose of this study was to histopathologically examine the healing of the grafted site around the implants at 12 months. Radiographic follow-up showed apparent bone apposition in the augmented area around the implants. Clinically, all 36 implants were stable and integrated with the surrounding tissue. Histopathologically, new bone formation was evident in all specimen hard tissue cores. Hydroxyapatite particles were present in direct contact with the remodeled osseous tissue. Mallory trichrome staining showed different stages of mineralization and maturation of the newly formed bone around the grafted mineral particles. Morphometric evaluation of Picrosirius red stained slides under polarized light microscopy was performed at the peripheral/external and deep section slides of all specimens. The average bone area fraction was 34.2%, with a 1 : 5.4 mean lamellar/woven bone ratio at the peripheral side and 53.0%, with 1 : 2.5 mean ratio at the deep side. The differences of both parameters between the two sites were statistically significant. B-SB proved to be a suitable grafting material with simultaneously placed implants in sinus floor augmentation procedures. [source]