Three-dimensional Visualization (three-dimensional + visualization)

Distribution by Scientific Domains


Selected Abstracts


Detection of different tumor growth kinetics in single transgenic mice with oncogene-induced mammary carcinomas by flat-panel volume computed tomography

INTERNATIONAL JOURNAL OF CANCER, Issue 1 2009
Katharina Jannasch
Abstract Transgenic mouse models offer an excellent opportunity for studying the molecular basis of cancer development and progression. Here we applied flat-panel volume computed tomography (fpVCT) to monitor tumor progression as well as the development of tumor vasculature in vivo in a transgenic mouse model for oncogene-induced mammary carcinogenesis (WAP-T mice). WAP-T mice develop multiple mammary carcinomas on oncogene induction within 3 to 5 months. Following induction, 3-dimensional fpVCT data sets were obtained by serial single scans of entire mice in combination with iodine containing contrast agents and served as basis for precise measurements of tumor volumes. Thereby, we were able to depict tumors within the mammary glands at a very early stage of the development. Tumors of small sizes (0.001 cm3) were detected by fpVCT before being palpable or visible by inspection. The capability to determine early tumor onset combined with longitudinal noninvasive imaging identified diverse time points of tumor onset for each mammary carcinoma and different tumor growth kinetics for multiple breast carcinomas that developed in single mice. Furthermore, blood supply to the breast tumors, as well as blood vessels around and within the tumors, were clearly visible over time by fpVCT. Three-dimensional visualization of tumor vessels in high resolution was enhanced by the use of a novel blood pool contrast agent. Here, we demonstrate by longitudinal fpVCT imaging that mammary carcinomas develop at different time points in each WAP-T mouse, and thereafter show divergent growth rates and distinct vascularization patterns. © 2009 UICC [source]


The development of 3-D visualization technology: the potential impact on interior design and its consumers

INTERNATIONAL JOURNAL OF CONSUMER STUDIES, Issue 5 2009
Seunghae Lee
Abstract Three-dimensional visualization has developed and improved significantly over the last several decades and resulted in consumers' having multidimensional, multi-sensory experiences with a wide range of products and services. It has affected the built environment and its related businesses. Designers create 3-D images and walk-through animations to communicate with their clients more clearly, starting from the early stage of the design process. The interior,design-related material manufacturers and retailers have enhanced their online stores with 3-D visualization features to improve their interactivity and provide user-friendly interfaces for product information search and purchase planning. Because of the continuing widespread interest in 3-D visualization and the amount of its applications in the interior design field, a review of this area was a necessity to suggest the future research direction for the development of 3-D visualization in interior design. This paper sought to demonstrate the status of the development of 3-D visualization and its impact on the interior design field and its consumers while highlighting an area where future research is a potentially considerable benefit in developing 3-D visualization in interior design. [source]


Three-dimensional visualization of bile canaliculi by confocal laser scanning microscopy

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, Issue 3 2002
K. Yoneyama
No abstract is available for this article. [source]


Three-dimensional visualization of the inner structure of single crystals by step-scanning white X-ray section topography

JOURNAL OF SYNCHROTRON RADIATION, Issue 6 2006
Taihei Mukaide
Visualization of the three-dimensional distribution of the crystal defects of large single crystals of calcium fluoride has been demonstrated by white X-ray section topography using sheet-like X-rays (BL28B2 at SPring-8). An image of the three-dimensional distribution of the crystal defects was reconstructed by stacking section topographs, which expressed the images of cross sections of the sample. The section topographs were recorded using a CMOS flat-panel imager or a CCD detector combined with scintillator (Gd2O2S:Tb) and relay lens system. The section topographs were measured by repeating cycles of exposure and sample translation along the direction perpendicular to the top face of the sample. Using high-brilliance and high-energy white X-rays (,60,keV) efficiently, visualization of the three-dimensional structure of subgrains of a sample of up to 60,mm in diameter was achieved. Furthermore, the three-dimensional distribution of the glide plane in the crystal was visualized by reconstructing the linear contrast of the glide plane. [source]


Three-dimensional visualization of renal artery stenosis by 64-channel multiple detector-row computed tomographical angiography: review of two paediatric cases

ACTA PAEDIATRICA, Issue 3 2010
N Ueda
Abstract Three-dimensional visualization of renal arteries has recently been established by helical contrast-enhanced multiple detector-row computed tomographical angiography (MDCTA) in adults. So far, no information is available on its use in children. We reported two children with renal artery stenosis detected by 64-channel MDCTA. The first patient probably had fibromuscular dysplasia and the other neurofibromatosis type1. The technique showed a left renal artery stenosis with a small left kidney in the first patient and a right renal artery stenosis in the second. Conclusion:, MDCTA is an accurate and noninvasive imaging technique, easily performed in children, and can be used as an alternative diagnostic modality in children with suspected renovascular hypertension. [source]


Cryoimmobilization and three-dimensional visualization of C. elegans ultrastructure

JOURNAL OF MICROSCOPY, Issue 1 2003
T. Müller-Reichert
Summary Caenorhabditis elegans is one of the most important genetic systems used in current biological research. Increasingly, these genetics-based research projects are including ultrastructural analyses in their attempts to understand the molecular basis for cell function. Here, we present and review state-of-the-art methods for both ultrastructural analysis and immunogold localization in C. elegans. For the initial cryofixation, high-pressure freezing is the method of choice, and in this article we describe two different strategies to prepare these nematode worms for rapid freezing. The first method takes advantage of transparent, porous cellulose capillary tubes to contain the worms, and the second packs the worms in E. coli and/or yeast paste prior to freezing. The latter method facilitates embedding of C. elegans in a thin layer of resin so individual worms can be staged, selected and precisely orientated for serial sectioning followed by immunolabelling or electron tomography. [source]


Identifying the course of an anomalous left coronary artery using contrast-enhanced electron beam tomography and three-dimensional reconstruction

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Issue 4 2002
Alexander Sevrukov MD
Abstract Coronary anomalies are a rare but recognized cause of myocardial ischemia and sudden death. Until recently, invasive coronary arteriography was the diagnostic method of choice. However, contrast-enhanced electron beam tomography has the advantage of three-dimensional visualization of anomalous coronary arteries. We describe a case of anomalous origin of the left coronary artery. Cathet Cardiovasc Intervent 2002;57:532,536. © 2002 Wiley-Liss, Inc. [source]