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Three-Component Synthesis (three-component + synthesis)

Distribution by Scientific Domains
Chemistry100%
Distribution within Chemistry
Organic Chemistry86%
General & Introductory Chemistry11%

Kinds of Three-Component Synthesis

  • one-pot three-component synthesis
    		•

    Selected Abstracts

    Catalysis by Ionic Liquids: Significant Rate Acceleration with the Use of [pmIm]Br in the Three-Component Synthesis of Dithio­carbamates

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 3 2008
    Brindaban C. Ranu
    Abstract An easily accessible neutral ionic liquid, 1-methyl-3-pentylimidazolium bromide, promoted a one-pot three-component condensation of an amine, carbon disulfide, and an activated alkene/dichloromethane/epoxide to produce the corresponding dithiocarbamates in high yields at room temperature. The reactions are very fast in ionic liquids relative to those in other reaction media. These reactions do not require any additional catalyst or solvent. The ionic liquid can be recovered and recycled for subsequent reactions. A plausible mechanism is suggested. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source]

    One-Pot Three-Component Synthesis of , -Amino Nitriles Catalyzed by 2,4,6-Trichloro-1,3,5-triazine (Cyanuric Acid),

    HELVETICA CHIMICA ACTA, Issue 6 2007
    Biswanath Das
    Abstract A simple and efficient method has been developed for the synthesis of , -amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature. [source]

    Facile One-Pot Three-Component Synthesis of Functionalized Pyridylfuran-2-amines

    HELVETICA CHIMICA ACTA, Issue 2 2006
    Mehdi Adib
    Abstract The reactive 1,:,1 zwitterionic intermediates generated in situ from the reaction between a series of isocyanides and diaroylacetylenes were trapped by pyridine carbaldehydes to yield highly functionalized 5-pyridylfuran-2-amines in good yields (82,93%). [source]

    Copper-Catalyzed Three-Component Synthesis of 2-Iminodihydrocoumarins and 2-Iminocoumarins

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7 2010
    Yang Shen
    Abstract An efficient synthesis of N -sulfonyl-substituted 2-imino-3,4-dihydrocoumarins and 2-iminocoumarins via a copper-catalyzed multicomponent reaction of sulfonyl azides with terminal alkynes and ,-(ortho -hydroxyphenyl)-,,,-unsaturated ketones or ortho -hydroxyphenylpropiolates has been developed. The cascade process involves trapping the keteimine by a nucleophilic addition and an intramolecular Michael addition. This methodology could well be extended to the concise synthesis of the polysubstituted piperidine scaffold. [source]

    Immobilization of Porphyrinatocopper Nanoparticles onto Activated Multi-Walled Carbon Nanotubes and a Study of its Catalytic Activity as an Efficient Heterogeneous Catalyst for a Click Approach to the Three-Component Synthesis of 1,2,3-Triazoles in Water

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14-15 2009
    Hashem Sharghi
    Abstract An efficient, regioselective, one-pot and two-step synthesis of ,-hydroxy 1,4-disubstituted 1,2,3-triazoles from a wide range of non-activated terminal alkynes and epoxides and sodium azide by way of a three-component click reaction using a catalytic amount of [meso -tetrakis(o -chlorophenyl)porphyrinato]copper(II) (5,mol%) in excellent isolated yields is described. The reactions were performed in water as a green solvent at ambient temperature without any additives. By performing two reaction steps in one pot and purifying only at the final step, this procedure excludes any interim purification of in situ generated organic azide intermediates, which significantly improves the overall yield and reduces the reaction time. To benefit from the recovery and reuse of the catalyst, a new heterogeneous catalyst was prepared by simple and successful impregnation of the catalyst onto activated multi-walled carbon nanotubes (AMWCNT). The heterogeneous catalyst was characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic forced microscopy (AFM), and thermogravimetric (TG) analysis to estimate the amount of nitrogen adsorption, and Raman and FT-IR spectroscopy. Leaching experiments after ten successive cycles showed that the catalyst is most strongly anchored to the AMWCNT support. Mechanistically, porphyrinatocopper catalyzes each step of the reaction in different ways as a bifunctional catalyst including epoxide ring opening by azide delivery to epoxide, forming in situ generated 2-azido alcohols followed by activation of the CC triple bond of the starting terminal alkynes by forming a porphyrinatocopper-acetylide intermediate and thereby promoting the [3+2]-cycloaddition reaction as the key step to form the triazole framework. [source]

    Highly Functionalised Enantiopure 4-Hydroxypyridine Derivatives by a Versatile Three-Component Synthesis

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7-8 2009
    Christian Eidamshaus
    Abstract The scope of a novel alkoxyallene-based pyridine synthesis was expanded to enantiopure carboxylic acids and nitriles as starting materials. The enantiomeric purity of the chiral ,-secondary carboxylic acids and nitriles was completely preserved during this reaction sequence thus allowing the one-pot preparation of a whole range of 4-hydroxypyridines or their 4-pyridinone tautomers in good yields. [source]

    ChemInform Abstract: Highly Efficient Three-Component Synthesis of 1H-Indazolo[1,2-b]phthalazinetrione Derivatives Catalyzed by Heteropolyacids.

    CHEMINFORM, Issue 37 2010
    Hong-Juan Wang
    Abstract The reaction conditions are optimized and a plausible reaction mechanism is proposed. [source]

    ChemInform Abstract: One-Pot, Three-Component Synthesis of 1-(2-Hydroxyethyl)-1H-1,2,3-triazole Derivatives by Copper-Catalyzed 1,3-Dipolar Cycloaddition of 2-Azido Alcohols and Terminal Alkynes under Mild Conditions in Water.

    CHEMINFORM, Issue 31 2010
    Hashem Sharghi
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Indium-Mediated One-Pot, Three-Component Synthesis of Homoallyl Alcohol Esters Without Catalysts and Dehydrants.

    CHEMINFORM, Issue 29 2010
    Zhengyin Du
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: An Expedient Three-Component Synthesis of Tertiary Benzylamines.

    CHEMINFORM, Issue 21 2010
    Erwan Le Gall
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Versatile Three-Component Synthesis of 2,-Amino-1,2-dihydrospiro[(3H)-indole-3,4,-(4,H)-pyran]-2-ones.

    CHEMINFORM, Issue 20 2010
    V. Yu.
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: 1-Butyl-3-methyl Imidazolium Hydrogen Sulfate Promoted One-Pot Three-Component Synthesis of Amidoalkyl Naphthols.

    CHEMINFORM, Issue 17 2010
    Suryakant B. Sapkal
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: One-Pot, Three-Component Synthesis of Chiral 4-Alkylidene-2-oxazolidinones.

    CHEMINFORM, Issue 17 2010
    Naoto Kojima
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: One-Step, Three-Component Synthesis of Highly Substituted Pyridines Using Silica Nanoparticle as Reusable Catalyst.

    CHEMINFORM, Issue 13 2010
    Subhash Banerjee
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Three-Component Synthesis of Functionalized Five-Membered Ring Lactones under Barbier-Like Conditions.

    CHEMINFORM, Issue 2 2010
    Camille Le Floch
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A Novel One-Pot, Three-Component Synthesis of 5-Imino-2,3,5,8-tetrahydropyrazolo[1,2-a]pyridazin-1-one Derivatives.

    CHEMINFORM, Issue 39 2009
    Bo Qian
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A General and Mild Copper-Catalyzed Three-Component Synthesis of Protected Homoallyl Amines.

    CHEMINFORM, Issue 38 2009
    Kalyan Kumar Pasunooti
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Consecutive Three-Component Synthesis of Ynones by Decarbonylative Sonogashira Coupling

    CHEMINFORM, Issue 38 2009
    Eugen Merkul
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Highly Functionalized Enantiopure 4-Hydroxypyridine Derivatives by a Versatile Three-Component Synthesis.

    CHEMINFORM, Issue 38 2009
    Christian Eidamshaus
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Tandem Oxidation Process Using Ceric Ammonium Nitrate: Three-Component Synthesis of Trisubstituted Imidazoles under Aerobic Oxidation Conditions.

    CHEMINFORM, Issue 25 2009
    Ahmad Shaabani
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Three-Component Synthesis of 1-Substituted 4-Acetyl-3-hydroxyspiro[2,5-dihydropyrrol-5,3,-indole]-2,2,-diones.

    CHEMINFORM, Issue 23 2009
    V. L. Gein
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Three-Component Synthesis of Fluorinated Pyrimidine Carbonitrile Derivatives under Thermal Aqueous Conditions.

    CHEMINFORM, Issue 3 2009
    Hassan Sheibani
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Regioselective Three-Component Synthesis of Highly Fluorescent 1,3,5-Trisubstituted Pyrazoles.

    CHEMINFORM, Issue 51 2008
    Benjamin Willy
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Ytterbium(III)-Perfluorooctanoate Catalyzed One-Pot, Three-Component Synthesis of Fully Substituted Pyrazoles under Solvent-Free Conditions.

    CHEMINFORM, Issue 40 2008
    Li Shen
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A Novel, One-Pot, Three-Component Synthesis of 5H-[1,3]Thiazolo[3,2-a]pyrimidine Derivatives.

    CHEMINFORM, Issue 10 2008
    Mehdi Adib
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: One-Pot Three-Component Synthesis of 3-Amino-5,8-dioxo-5,8-dihydro-1H-pyrazolo[1,2-a]pyridazines (IV).

    CHEMINFORM, Issue 7 2008
    Mehdi Adib
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A New, One-Pot, Three-Component Synthesis of 4H-Pyrido[1,2-a]pyrimidines, 4H-Pyrimido[1,2-a]pyrimidines, and 4H-Pyrazino[1,2-a]pyrimidines.

    CHEMINFORM, Issue 6 2008
    Mehdi Adib
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    A Resource-Efficient and Highly Flexible Procedure for a Three-Component Synthesis of 2-Imidazolines.

    CHEMINFORM, Issue 51 2007
    Niels Elders
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    A SiCl4,ZnCl2 Induced General, Mild and Efficient One-Pot Three-Component Synthesis of ,-Amido Ketone Libraries.

    CHEMINFORM, Issue 50 2007
    Tarek A. Salama
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    A Novel One-Pot Three-Component Synthesis of 2,4-Disubstituted-3H-benzo[b][1,4]diazepines in Water.

    CHEMINFORM, Issue 28 2007
    Sanjay S. Palimkar
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]