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Basic Issues (basic + issues)
Selected AbstractsMicrofluidics: Basic issues, applications, and challengesAICHE JOURNAL, Issue 6 2001H. A. Stone First page of article [source] Self-Assembled Monolayers into the 21st Century: Recent Advances and ApplicationsELECTROANALYSIS, Issue 2 2003Justin Gooding Abstract The modification of an interface on a molecular level with more than one molecular ,building block' is essentially an example of the ,bottom,up' fabrication principle of nanotechnology. The fabrication of such integrated molecular systems in electrochemistry has seen rapid progress in recent years via the development of sensing interfaces fabricated using self-assembled monolayers (SAMs). This review outlines recent advances and applications of self-assembled monolayers for modifying electrodes with an emphasis on the development of integrated molecular systems. First, some basic issues regarding fabricating integrated molecular systems, such as the role of the surface topography of the electrode and patterning surfaces, are discussed. Subsequently an overview of recent developments in pH, inorganic and bio sensing involving the use of SAMs is given. Finally emerging trends in using molecular building blocks in the fabrication of integrated molecular systems, such as nanotubes, dendrimers and nanoparticles, are reviewed. [source] Ilim Pulp, blending former Russian state enterprises, creates a corporate university to change culture, become an industry leaderGLOBAL BUSINESS AND ORGANIZATIONAL EXCELLENCE, Issue 5 2010Marina O. Latuha This article describes the establishment of a corporate university in a Russian company. Following the economic restructuring of the country, training and personnel development became vital ingredients in the company's long-term strategy. In these turbulent conditions, the company realized that it needed to have the training and personnel development characterized by continuity on the one hand and revolutionary changes in organizational culture on the other. If this could be achieved, it would encourage entrepreneurship, innovation, and change in the internal processes of the organization. The case describes the stages, programs, and basic components of the corporate university model. It not only illustrates the basic issues in the application of corporate training theory, but also analyzes the risks and problems for the company in the project's realization. The article concludes with a description of how the corporate university developed after its initiation, and some conclusions about the overall success of the project. © 2010 Wiley Periodicals, Inc. [source] Recent Progress in n-Channel Organic Thin-Film TransistorsADVANCED MATERIALS, Issue 12 2010Yugeng Wen Abstract Particular attention has been focused on n-channel organic thin-film transistors (OTFTs) during the last few years, and the potentially cost-effective circuitry-based applications in flexible electronics, such as flexible radiofrequency identity tags, smart labels, and simple displays, will benefit from this fast development. This article reviews recent progress in performance and molecular design of n-channel semiconductors in the past five years, and limitations and practicable solutions for n-channel OTFTs are dealt with from the viewpoint of OTFT constitution and geometry, molecular design, and thin-film growth conditions. Strategy methodology is especially highlighted with an aim to investigate basic issues in this field. [source] Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applicationsNMR IN BIOMEDICINE, Issue 5 2004Bernard Gallez Abstract This review paper attempts to provide an overview of the principles and techniques that are often termed electron paramagnetic resonance (EPR) oximetry. The paper discusses the potential of such methods and illustrates they have been successfully applied to measure oxygen tension, an essential parameter of the tumor microenvironment. To help the reader understand the motivation for carrying out these measurements, the importance of tumor hypoxia is first discussed: the basic issues of why a tumor is hypoxic, why these hypoxic microenvironments promote processes driving malignant progression and why hypoxia dramatically influences the response of tumors to cytotoxic treatments will be explained. The different methods that have been used to estimate the oxygenation in tumors will be reviewed. To introduce the basics of EPR oximetry, the specificity of in vivo EPR will be discussed by comparing this technique with NMR and MRI. The different types of paramagnetic oxygen sensors will be presented, as well as the methods for recording the information (EPR spectroscopy, EPR imaging, dynamic nuclear polarization). Several applications of EPR for characterizing tumor oxygenation will be illustrated, with a special emphasis on pharmacological interventions that modulate the tumor microenvironment. Finally, the challenges for transposing the method into the clinic will also be discussed. Copyright © 2004 John Wiley & Sons, Ltd. [source] Training to Provide for Healthy Rural AgingTHE JOURNAL OF RURAL HEALTH, Issue 4 2001B.A.(Hons), Joseph Troisi Ph.D., M. Phil., M.A.(Soc), M.Th. ABSTRACT: More than 60 percent of the world's aged population is in developing countries, the majority living in rural and remote areas. Resources in these areas are scarce and there is a lack of services and programs, especially in the areas of health, housing and social welfare. The most serious deficiency faced by many countries in meeting the challenges of population aging is the pronounced scarcity of trained caregivers. Little attention has been given to developing effective training policies and programs. Most of the people providing a service to older people lack basic training and this is more so in rural and remote areas. The processes for extending liealthy aging and postponing the onset of chronic diseases and disabling conditions exist already. Unfortunately, these processes are not disseminated in appropriate ways. It is therefore imperative to disseminate this information by training people at the grass roots level to reach the most vulnerable and isolated older people. Primary care workers should have the necessary skills, knowledge and techniques to facilitate good care of older people in their environment. This article reviews and analyzes attempts being made by a number of countries to meet this need. Though the basic issues dealt with are often the same, the approach used differs. [source] Patients' Sexual Health: A Qualitative Research Approach on Greek Nurses' PerceptionsTHE JOURNAL OF SEXUAL MEDICINE, Issue 8 2009Evangelia Nakopoulou MSc ABSTRACT Introduction., Health care professionals, especially nurses, through their contact with patients, play an important role in encouraging discussions about sexual concerns. Aim., To explore perceptions on sexual health issues and how these might inhibit or enhance Greek nurses' ability to incorporate sexual health assessment into everyday practice. Main Outcome Measures., A discussion guide was used as checklist to ensure that the basic issues would be addressed. Topics related to the areas of interest were either brought up from the participants or introduced by the moderator. Methods., The study recruited a purposive sample of 44 Greek staff nurses (SN) attending a course leading to their professional upgrading. A qualitative research design was employed using seven focus groups. Discussions started with nurses' perceived definitions of sexual health and proceeded with open-ended questions. Transcripts were analyzed using thematic analysis based on the principles of grounded theory. Results., Three central themes were identified from transcripts' thematic analysis: subjective perception of sexual health, discussing sexual problems, and educational and training needs. Participants' perceptions of sexual health centred mainly on the emotional and somatic dimensions. Regarding clinical practice, a variety of personal and contextual reasons limit nurses' willingness to talk about sexuality with patients, such as gender and age differences, familial upbringing, lack of time and privacy, and restricted perception of nursing role. All nurses stressed the need for further specialized training not only in physiology issues related to sexuality, but also most importantly in communication skills. Conclusions., Although Greek nurses acknowledge the importance of sexual health assessment, they believe that sexual history taking is not within the range of their professional tasks. Since holistic care demands sexual health assessment and intervention to be an integral part of nursing practice, it is necessary to introduce courses in their curriculum and experiential workshops addressing the multidimensionality of sexuality. Nakopoulou E, Papaharitou S, and Hatzichristou D. Patients' sexual health: A qualitative research approach on Greek nurses' perceptions. J Sex Med 2009;6:2124,2132. [source] Behavior of Cardiomyocytes and Skeletal Muscle Cells on Different Extracellular Matrix Components,Relevance for Cardiac Tissue EngineeringARTIFICIAL ORGANS, Issue 1 2007Karin Macfelda Abstract:, Myocardial cell transplantation in patients with heart failure is emerging as a potential therapeutic option to augment the function of remaining myocytes. Nevertheless, further investigations on basic issues such as ideal cell type continue to be evaluated. Therefore, the aim of our studies was to compare the performance of skeletal muscle cells and cardiomyocytes with respect to their proliferation rate and viability on different extracellular matrix components (EMCs). Rat cardiomyocytes (RCM) and rat skeletal muscle cells (RSMC) were cultured on EMCs such as collagen type I, type IV, laminin, and fibronectin. The components were used as "single coating" as well as "double coating." Proliferation rates were determined by proliferation assays on days 1, 2, 4, and 8 after inoculation of the cells. The most essential result is that collagen type I enhances the proliferation rate of RSMC but decreases the proliferation of RCM significantly. This effect is independent of the second EMC used for the double-coating studies. Other EMCs also influence cellular behavior, whereas the sequence of the EMCs is essential. Results obtained in our studies reveal the significant different proliferation behavior of RCM and RSMC under identical conditions. As skeletal muscle cells are also used in heart tissue engineering models, these results are essential and should be investigated in further studies to prove the applicability of skeletal muscle cells for heart tissue engineering purposes. [source] | |||||||||||||