Thermal Burns (thermal + burn)

Distribution by Scientific Domains

Selected Abstracts

Thermal burn following combined use of forced air and fluid warming devices

ANAESTHESIA, Issue 6 2010
S. M. Siddik-Sayyid
No abstract is available for this article. [source]

Long-term functional and anatomical results of OOKP and tibial OKP: Barcelona experience

Purpose To report the long-term functional and anatomical results of OOKP and Tibial OKP performed at the Barraquer Eye Center from 1974-2006. Different factors like surgical technique, clinical diagnosis, age and post-operative complications are also analyzed and reported. Methods A retrospective study on 330 eyes of 227 patients who underwent OOKP or tibia OKP was performed. Kaplan Meier survival curves and multivariate analysis using Cox regression model of the different variables mentioned are presented. Results OOKP and Tibia OKP have comparable functional and anatomical results in the long-term. Best long-term functional and anatomical results are for patients with chemical burns, cicatricial trachoma and Stevens-Johnsons/Lyell syndrome. Thermal burns have a higher anatomical retention than other diagnostic categories. Younger patients have better visual prognosis and anatomical retention than older patients. Patients must be warned of the possibility of sight-threatening complications like extrusion of the prosthesis, retinal detachment and glaucoma. Conclusion Our more than 35 years experience with biological keratoprosthesis using the OOKP and the tibia OKP shows that the two techniques are comparable. Certain variables like clinical diagnosis, age and post-operative complications affect the anatomical and functional results in the long-term. [source]

3235: Application of autologous cultivated corneal epithelium for restoring of corneal surface

Purpose To present results of transplantations of cultured corneal epithelium in limbal stem cell insufficiency. Methods 26 patients were donors of limbal epithelium for corneal epithelial culture. Patients suffered from limbal deficiency in one eye after chemical or thermal burn. Limbal cells from 2 mm2 biopsy were seeded on amniotic membrane. Cultures were carried in standard conditions in supplememted DMEM in presence of 3T3 fibroblasts. After superficial keratectomy amniotic carries with epithelial cells were transplanted on denuded corneas. Stabilisation of corneal surface was evaluated. Results 3 months after surgery 61,5% of eyes showed stabile epithelium with corneal slight haze caused by the amnion. In 50,0% of eyes there was no recurrent conjuntival neovascularisation. 38,4% of eyes remained cloudy due to stromal revascularization. In 4 eyes total conjuctival pannus developed again. Visual acuity ranged from counting fingers to 0,5. Conclusion Grafting of cultured epithelium is a promising method in treatment of limbal stem cell insufficiency in burns. [source]

Curling Iron-related Injuries Presenting to U.S. Emergency Departments

Khajista Qazi MD
Abstract. Objective: To describe curling iron-related injuries reported to the National Electronic Injury Surveillance System (NEISS) between January 1, 1992, and December 31, 1996. Methods: The authors retrospectively reviewed data from NEISS, a weighted probability sample of emergency departments (EDs) developed to monitor consumer product-related injuries. The information reported includes patient demographics, injury diagnosis, body part injured, incident locale, patient disposition, and a brief narrative description. The authors reviewed the narrative in the hair care products category and abstracted records indicating the injury was caused by contact with a curling iron. Also analyzed were the design features of commonly available curling irons purchased from national discount department stores. Results: There were an estimated 105,081 hair care product-related injuries in the five-year period, of which 82,151 (78%) involved a curling iron. Seventy percent of injuries were to females. The patient's median age was 8 years (range 1 month to 96 years). The most commonly occurring injury was thermal burns (97%; 79,912/82,151). Ninety-eight percent of the injuries occurred in the home and 99% of the patients were discharged home from the ED. In patients <4 years old, 56% of burns occurred by grabbing or touching, while in those ,10 years the burns occurred by contact while in use. In the older group 69% of burns were of the cornea. Most curling irons use small amounts of power, yet there are no standards for temperature settings or control. The cylinder containing the heating element is mostly exposed, and many irons do not have a power switch. Conclusions: The most common injury resulting from curling irons is thermal burns. The mechanisms and patterns of injury in developmentally distinct age groups suggest that many of these injuries could be prevented by public education and the re-engineering of curling irons. [source]

Cholinergic control of epidermal cohesion

Sergei A. Grando
Abstract:, The non-neuronal cholinergic system of human epidermis includes the keratinocyte (KC) acetylcholine (ACh) axis composed of the enzymes mediating ACh synthesis and degradation, and two classes of ACh receptors, the nicotinic and muscarinic ACh receptors, mediating biological effects of the cutaneous cytotransmitter ACh. Regulation of KC cell,cell and cell,matrix adhesion is one of the important biological functions of cutaneous ACh. The downstream targets of ACh effects mediated by distinct ACh receptor subtypes include both the intercellular adhesion molecules, such as classical and desmosomal cadherins, and integrins mediating KC adhesion to a substrate. The signaling pathways include activation or inhibition of kinase cascades resulting in either up- or down-regulation of the expression of cell adhesion molecules or changes in their phosphorylation status, or both. The components of the KC ACh axis are involved in cutaneous blistering in patients with autoimmune pemphigus, junctional and dystrophic forms of epidermolysis bullosa, thermal burns, and mustard-induced vesication. Recent progress with the development of antiacantholytic therapies of patients with pemphigus using cholinomimetics indicates that cholinergic drugs may be a promising approach for other cutaneous blistering disorders. [source]

The immunocompromised district: a unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites

V Ruocco
Abstract Systemic immunodeficiency is known to facilitate the onset of opportunistic infections, tumours and immune disorders in any district of the body. There are clinical events, such as chronic lymphoedema, herpetic infections, vaccinations and heterogeneous physical injuries which can selectively damage and immunologically mark the cutaneous district they act upon. After the causing event has disappeared, the affected district may appear clinically normal, but its immune behaviour is often compromised forever. An immunocompromised district becomes a site which is particularly susceptible to subsequent outbreaks of opportunistic infections, tumours and immune disorders confined to the district itself. In this review, there is an ample case-report collection of opportunistic disorders (infectious, neoplastic, immune) which appeared in immunocompromised districts. The cases have been grouped according to the clinical settings responsible for the local immune imbalance: regional chronic lymphoedema; herpes-infected sites, which feature the well-known Wolf's isotopic response; and otherwise damaged areas, comprising sites of vaccination, ionizing or UV radiation, thermal burns and traumas. Whatever the immunocompromising factor, a common denominator which facilitates the occurrence of tumours, infections and dysimmune reactions in an immunocompromised district may reside in locally hampered lymph drainage and/or locally altered neuromediator signalling. In fact, any obstacle to the normal trafficking of immunocompetent cells through lymphatic channels or any interference with the signals that the neuropeptides and neurotransmitters released by peripheral nerves send to cell membrane receptors of immunocompetent cells, can significantly alter the local immune response, thus paving the way for heterogeneous opportunistic disorders in the immunocompromised district. [source]

Spontaneous cecum perforation following rectus abdominis free flap transfer for isolated lower limb trauma

MICROSURGERY, Issue 3 2009
Ch.B., Roger J. G. Stevens M.Sc.
A case of a 32-year-old motorcyclist, who sustained an open comminuted fracture of the left tibia and subsequently developed spontaneous cecal perforation following successful fixation of the fracture and reconstruction of the soft tissue defect with a rectus abdominis free flap, is reported. Although benign cecal perforation has been described in patients with thermal burns and blunt trauma of the abdomen or pelvis, our association has not been reported previously in the medical literature. It is important to recognize cecal perforation early as it is associated with a high mortality from peritonitis and septicaemia. 2009 Wiley-Liss, Inc. Microsurgery, 2009. [source]

Devices for Noninvasive Transcranial Electrostimulation of the Brain Endorphinergic System: Application for Improvement of Human Psycho-Physiological Status

Valery P. Lebedev
Abstract: It is well known that deficit of endorphins plays an important role in disturbances of human psycho-physiological status. Previously, we revealed that brain endorphinergic structures have quasiresonance characteristics. On the basis of these data, a method of activation of the brain endorphinergic structures by means of noninvasive and rather selective transcranial electrostimulation (TES) as a kind of functional electrical stimulation (FES) was elaborated. New models of TES devices (TRANSAIR) were developed for indoor and outdoor usage. To increase the efficacy of TES, the frequency modulation according to normal distribution in the limits of the quasiresonance characteristics was put into operation. The blind and placebo-controlled (passive and active placebo) study was produced to estimate the TES effects on stress events and accompanied psycho-physiological and autonomic disturbances of different intensities on volunteers and patients in the following groups: everyday stress and fatigue; stress in regular military service and in field conditions; stress in the relatives of those lost in mass disaster; posttraumatic stress (thermal burns); and affective disorders in a postabstinence period. Some subjective verbal and nonverbal tests and objective tests (including heart rate variability) were used for estimation of the initial level of psycho-physiological status, which changes after TES sessions. It was demonstrated that fatigue, stress, and other accompanied psycho-physiological disturbances were significantly improved or abolished after 2,5 TES sessions. The TES effects were more pronounced in cases of heavier disturbances. In conclusion, activation of the brain endorphinergic structures by TES is an effective homeostatic method of FES that sufficiently improves quality of life. [source]