Technology

Distribution by Scientific Domains

Kinds of Technology

  • access technology
  • advanced technology
  • agent technology
  • agilent technology
  • agricultural technology
  • alternative technology
  • analytical technology
  • and technology
  • application technology
  • appropriate technology
  • array technology
  • assisted reproductive technology
  • assistive technology
  • available technology
  • basic technology
  • bead array technology
  • bioremediation technology
  • biosensor technology
  • care technology
  • cdna microarray technology
  • cell technology
  • chemical technology
  • chip technology
  • circuit technology
  • clean technology
  • cmo technology
  • coating technology
  • column technology
  • communication technology
  • component technology
  • computer technology
  • computing technology
  • contemporary technology
  • control technology
  • conventional technology
  • conversion technology
  • crystallization technology
  • current technology
  • deposition technology
  • detection technology
  • developed technology
  • developing technology
  • device technology
  • diagnostic technology
  • different technology
  • digital technology
  • display technology
  • disruptive technology
  • dna microarray technology
  • dna sequencing technology
  • dna technology
  • educational technology
  • effective technology
  • electronic nose technology
  • electronic technology
  • emerging technology
  • enabling technology
  • energy technology
  • energy-saving technology
  • engineering technology
  • enhancement technology
  • evolving technology
  • existing technology
  • experimental technology
  • fabrication technology
  • fermentation technology
  • food technology
  • fuel cell technology
  • future technology
  • gene technology
  • gene transfer technology
  • general-purpose technology
  • generation technology
  • genetic technology
  • genomic technology
  • genotyping technology
  • green technology
  • grid technology
  • health information technology
  • health technology
  • high technology
  • high-throughput technology
  • human performance technology
  • hybridoma technology
  • identification technology
  • imaging technology
  • implant technology
  • important technology
  • improved technology
  • individual technology
  • information communication technology
  • information system technology
  • information technology
  • innovative technology
  • instructional technology
  • integrated circuit technology
  • internet technology
  • irrigation technology
  • key technology
  • laser technology
  • learning technology
  • lithic technology
  • management of technology
  • management technology
  • manufacturing technology
  • marker technology
  • mass spectrometry technology
  • mature technology
  • media technology
  • medical technology
  • mem technology
  • membrane technology
  • microarray technology
  • microfabrication technology
  • microfluidic technology
  • microreaction technology
  • microstrip technology
  • microwave technology
  • mobile technology
  • modern technology
  • molecular imaging technology
  • molecular technology
  • monitoring technology
  • mr technology
  • multidimensional protein identification technology
  • navigation technology
  • network technology
  • new communication technology
  • new computer technology
  • new media technology
  • new reproductive technology
  • new technology
  • newer technology
  • next-generation sequencing technology
  • nm cmo technology
  • nose technology
  • novel technology
  • of technology
  • omic technology
  • online technology
  • other technology
  • packaging technology
  • particular technology
  • pcr technology
  • performance technology
  • phage display technology
  • pharmaceutical technology
  • postharvest technology
  • power generation technology
  • powerful technology
  • pretreatment technology
  • printing technology
  • probe technology
  • process analytical technology
  • process technology
  • processing technology
  • production technology
  • promising technology
  • proposed technology
  • protein identification technology
  • proteomic technology
  • pump technology
  • reality technology
  • recombinant dna technology
  • relate technology
  • remote sensing technology
  • reproduction technology
  • reproductive technology
  • rnai technology
  • robotic technology
  • same technology
  • scanning technology
  • science and technology
  • screening technology
  • selection technology
  • sensing technology
  • sensor technology
  • separation technology
  • sequencing technology
  • similar technology
  • simulation technology
  • software technology
  • spectrometry technology
  • standard technology
  • storage technology
  • surgical technology
  • synthesis technology
  • system technology
  • telecommunication technology
  • therapeutic technology
  • throughput technology
  • today technology
  • touch-screen technology
  • traditional technology
  • transfer technology
  • transgenic technology
  • transmission technology
  • treatment technology
  • ultrasound technology
  • useful technology
  • various technology
  • virtual reality technology
  • web technology
  • wireless technology

  • Terms modified by Technology

  • technology acceptance
  • technology acceptance model
  • technology adoption
  • technology assessment
  • technology available
  • technology choice
  • technology commercialization
  • technology company
  • technology development
  • technology development organization
  • technology diffusion
  • technology firm
  • technology impact
  • technology inc.
  • technology industry
  • technology integration
  • technology investment
  • technology management
  • technology officer
  • technology option
  • technology platform
  • technology policy
  • technology process
  • technology project
  • technology research
  • technology sector
  • technology shock
  • technology skill
  • technology standards
  • technology studies
  • technology tool
  • technology transfer
  • technology uncertainty
  • technology use
  • technology used

  • Selected Abstracts


    Four-Year Follow-up on Endovascular Radiofrequency Obliteration of Great Saphenous Reflux

    DERMATOLOGIC SURGERY, Issue 2 2005
    Robert F. Merchant MD
    Background Endovascular radiofrequency obliteration has been used since 1998 as an alternative to conventional vein stripping surgery for elimination of saphenous vein insufficiency. Objective To demonstrate the long-term efficacy of this treatment modality. Methods Data were prospectively collected in a multicenter ongoing registry. Only great saphenous vein above-knee treatments were included in this study. Eight hundred ninety patients (1,078 limbs) were treated prior to November 2003 at 32 centers. Clinical and duplex ultrasound follow-up was performed at 1 week, 6 months, and 1, 2, 3, and 4 years. Results Among 1,078 limbs treated, 858 were available for follow-up within 1 week, 446 at 6 months, 384 at 1 year, 210 at 2 years, 114 at 3 years, and 98 at 4 years. The vein occlusion rates were 91.0%, 88.8%, 86.2%, 84.2%, and 88.8%, respectively; the reflux-free rates were 91.0%, 89.3%, 86.2%, 86.0%, and 85.7%, respectively; and the varicose vein recurrence rates were 7.2%, 13.5%, 17.1%, 14.0%, and 21.4%, respectively, at each follow-up time point at 6 months, and 1, 2, 3, and 4 years. Patient symptom improvement persisted over 4 years. Conclusions Endovascular temperature-controlled radiofrequency obliteration of saphenous vein reflux exhibits an enduring treatment efficacy clinically, anatomically, and hemodynamically up to 4 years following treatment. ROBERT F. MERCHANT, MD, AND OLIVIER PICHOT, MD, ARE PAID CONSULTANTS TO VNUS MEDICAL TECHNOLOGIES, WHICH PROVIDED FINANCIAL SUPPORT FOR THIS STUDY. [source]


    CONSUMER PREFERENCES FOR PATHOGEN-REDUCING TECHNOLOGIES IN BEEF,

    JOURNAL OF FOOD SAFETY, Issue 2 2001
    KRISTA FINGERHUT
    ABSTRACT Two surveys were conducted by mail to evaluate consumers' preferences for beef treated by the steam and hot-water pasteurization technologies, in a comparison with beef treated by irradiation and nontechnology treated "regular" beef. More than 64% of the respondents reported that they preferred ground beef treated by irradiation to that treated by the two pathogen-reducing technologies. More than 87% of the respondents stated that they preferred ground beef treated by the two technologies to nontechnology treated beef. Sixty percent of the respondents reported that they were willing to pay for beef treated by the two pathogen-reducing technologies with an averaged willingness-to-pay of 0.36/lb over nontechnology treated beef. Compared with their counterparts; women, those having a better self-reported health status, and those with children at home (, 18 years of age) were more likely to report a preference for beef treated by the two heat-related pasteurization technologies. The income level of the respondents was negatively associated with their preference for beef treated by the two heat-related pasteurization technologies. The strong consumer preference coupled with willingness-to-pay for beef treated by the two pathogen-reducing technologies, suggest that consumers are willing to bear the cost of using these technologies if beef packers would invest in such technologies as a means of improving the quality of their products. [source]


    THE DOUBLE ROLE OF SKILLED LABOR, NEW TECHNOLOGIES AND WAGE INEQUALITY

    METROECONOMICA, Issue 1 2005
    Hartmut Egger
    ABSTRACT We examine the relationship between the supply of skilled labor, technological change and relative wages. In accounting for the role of skilled labor in both production activities and productivity- enhancing ,support' activities we derive the following results. First, an increase in the supply of skilled labor raises the employment share of non-production labor within firms, without lowering relative wages. Second, new technologies raise wage inequality only in so far as they give incentives to firms to reallocate skilled labor towards non-production activities. In contrast, skill-biased technological change of the sort usually considered in the literature does not affect wage inequality. [source]


    FOUR GENEALOGIES FOR A RECOMBINANT ANTHROPOLOGY OF SCIENCE AND TECHNOLOGY

    CULTURAL ANTHROPOLOGY, Issue 4 2007
    MICHAEL M. J. FISCHER
    First page of article [source]


    PRODUCTIVITY AND THE PENETRATION OF INFORMATION TECHNOLOGY

    ECONOMIC PAPERS: A JOURNAL OF APPLIED ECONOMICS AND POLICY, Issue 4 2001
    HUW McKAY
    First page of article [source]


    ON PERSON, TECHNOLOGY, AND EDUCATION

    EDUCATIONAL THEORY, Issue 1 2001
    Ignacio L. Götz
    First page of article [source]


    TWENTY-FIRST CENTURY PINK OR BLUE: HOW SEX SELECTION TECHNOLOGY FACILITATES GENDERCIDE AND WHAT WE CAN DO ABOUT IT

    FAMILY COURT REVIEW, Issue 1 2008
    Monica Sharma
    In the midst of a genetic revolution in medicine, Assisted Reproductive Technology (ART) has become a well-established technique to help infertile women achieve pregnancy. But many women are now turning to ART not just to circumvent infertility, but consciously to shape their families by determining the sex of their children. Many patriarchal cultures have a gender preference for males and to date have used technological advances in reproductive medicine to predetermine the sex of the child being born. Women have sought sex-selective abortions, where the pregnancy was being terminated solely on the basis of the sex of the unborn fetus. The combination of ART advances and gender preference has led to the disappearance of at least 100 million girls from the world's population leading to a mass gendercide. This article examines the societal impact of unbalanced gender ratios and the need to regulate sex selection to avoid nations of bachelors. [source]


    MEDICAL CARE AND TECHNOLOGY

    JOURNAL OF CLINICAL HYPERTENSION, Issue 10 2005
    Paul A. Macri MD
    No abstract is available for this article. [source]


    FOOD PACKAGING SCIENCE AND TECHNOLOGY

    JOURNAL OF FOOD PROCESSING AND PRESERVATION, Issue 1 2009
    Shyam S. Sablani Assistant Professor/Scientist
    No abstract is available for this article. [source]


    ANGLES OF INTEGRATION: AN EMPIRICAL ANALYSIS OF THE ALIGNMENT OF INTERNET-BASED INFORMATION TECHNOLOGY AND GLOBAL SUPPLY CHAIN INTEGRATION

    JOURNAL OF SUPPLY CHAIN MANAGEMENT, Issue 2 2010
    JÖRN-HENRIK THUN
    This paper investigates the relationship between the focus and implementation degree of Internet-based information technology (IT) applications and the scope and orientation of process-oriented integration in global supply chains. Using data from 205 plants, which were collected in conjunction with the High Performance Manufacturing project, the degree of supplier and customer integration and its match with the implemented IT instruments supporting interorganizational collaboration are investigated empirically. Different types of integration are differentiated from each other with the help of factor, percentile and cluster analyses. The focus and degree of IT integration is measured for each of the resulting groups and the alignment of both aspects is analyzed with the help of an approach referred to as the angles of integration. With respect to supply chain integration and IT implementation, the analysis of different integration strategies shows that most of the plants do not align their IT implementation with their supply chain strategy. The paper helps companies to evaluate the alignment of their use of IT techniques with their global supply chain management emphases. Additionally, possible reasons for a potential missmatch of functional strategies are discussed giving managers insights for dealing more effectively with a strategic alignment. Furthermore, it refines an existing framework for the comparison of different supply chain integration strategies and applies it with IT. Based on the angles of integration, the match of supply chain integration and IT is investigated by statistical analyses. [source]


    SCIENCE, TECHNOLOGY AND THE NEW PRESIDENT: SECURITY, PROSPERITY AND STABILITY IN THE 21ST CENTURY

    POLITICS & POLICY, Issue 6 2008
    Robert McCreight
    No abstract is available for this article. [source]


    SALES TECHNOLOGY AND PRICE LEADERSHIP,

    THE MANCHESTER SCHOOL, Issue 2 2008
    DEBABRATA DATTA
    Two firms sell a homogeneous product to two buyers who differ significantly in their valuation of the good and are allowed to charge (possibly) multiple two-part tariffs. Firms decide upon optimal prices and the choice of sales technologies which help acquire revenues from nonlinear prices. There is a subgame-perfect equilibrium where firms choose different sales technologies and the firm with an advanced sales technology emerges to be a price leader, charging a two-part tariff and selling only to the low-valuation buyers. Consequently, the firm with the less advanced sales technology follows, charges only a fixed fee and serves the high-valuation buyers and always earns strictly higher profits than its leader. Social surplus may deteriorate with competition. [source]


    Front and Back Covers, Volume 25, Number 5.

    ANTHROPOLOGY TODAY, Issue 5 2009
    October 200
    Front and back cover caption, volume 25 issue 5 FIELDWORK AND TECHNOLOGY The images on the front and back covers illustrate two of several reflections in this issue on the impacts of technology on the world studied by anthropologists. On the front cover, an internet cafe is one of the first sights to greet visitors to Dhunche, once a ,remote' area in northern Nepal. On the back cover, a youth tries out a telescope during the commemoration of the confirmation of Einstein's General Theory of Relativity at Roça Sundy, Príncipe, where Arthur Eddington observed a total solar eclipse. In his editorial, Bob Simpson remarks on how much the craft of fieldwork has changed as a result of the widespread on-site availability of communications technology, placing even the remotest sites within reach of home or employer. In this post-Malinowskian fieldwork, where the distinction between back here and out there has disappeared, what are the implications of this for our craft and for the quality of our obversations? Gisa Weszkalnys reflects on her fieldwork site of Príncipe as the location of one of the most important events in 20th-century science, the confirmation of Einstein's General Theory of Relativity. She overlays the 2009 commemoration of this event, with international institutions promoting scientific knowledge and tourism, with another, colonial history of Príncipe as the focus of a controversy around the alleged use of slave labour in its cocoa plantations. As Kristín Loftsdóttir argues in her article, science and technology are among a range of markers used to determine who is most in need of international development, thus contributing to what she calls the ,racialization of development'. Akbar Ahmed alerts us to the fear in Washington, DC and Islamabad that the Taliban, who have recently taken over his field site in Swat Province, could potentially destabilize world order by appropriating nuclear technology. There are evidently many ways in which science and technology can and do affect our field sites. One of the greatest challenges for anthropology will be to experiment creatively and innovate with appropriate technologies in partnership. In this way we can generate more egalitarian conversations in an atmosphere of mutual respect, trust and tolerance. Whatever fieldwork becomes, it must be founded on such engagement with the broadest of publics, while making the most of these new technologies. [source]


    PRODUCTION TECHNOLOGY OF ROMAN LEAD-GLAZED POTTERY AND ITS CONTINUANCE INTO LATE ANTIQUITY

    ARCHAEOMETRY, Issue 5 2010
    M. S. WALTON
    A broad selection of Roman lead-glazed pottery dating from the first century ad through the fifth century ad was studied to establish locations of workshops and to address their technology of production. The ceramic bodies were analysed by ICP,AES. In addition, lead isotope analysis was undertaken on a selection of glazes. These findings suggested that there were several regions responsible for the production of lead-glazed ceramics in the western Roman world, including central Gaul, Italy and, probably, Serbia and Romania. Using the body compositions as a starting point, the glazing techniques employed by each of the potential workshops were examined using electron probe microanalysis. It was determined that there were two primary methods of glazing. The first method used lead oxide by itself applied to non-calcareous clay bodies, and the second method used a lead oxide-plus-quartz mixture applied to calcareous clay bodies. Based on these data for clay composition and glazing method, transfer of technology from the Hellenistic east to the western Roman world was proposed. Likewise, the inheritance of lead-glazing technology into late antiquity was established by making comparisons to lead-glazed ceramics dating to the seventh to ninth centuries from Italy, the Byzantine world and Tang Dynasty China. [source]


    THE TECHNOLOGY OF PRODUCTION OF SASANIAN GLAZED POTTERY FROM VEH ARDA,?R (CENTRAL IRAQ)

    ARCHAEOMETRY, Issue 4 2008
    M. PACE
    Scanning electron microscopy coupled with an energy dispersive X-ray detector (SEM-EDS) has been used to study samples of Sasanian glazed pottery. Analysis of ceramic bodies revealed a general homogeneity in composition among the studied samples and the use of calcareous clay for their manufacture. Glazes are typically alkaline in composition, with sodium and potassium oxide contents between 8 and 13%, and between 3 and 5%, respectively; calcium and magnesium oxide contents are between 7 and 10%, and between 3 and 5%, respectively. These data suggest the use of plant ash together with a silica source for glaze production. Coating thickness is highly variable among different samples, from some 400 up to 1200 µm, but it is generally uniform when a single sample is concerned. Glazes are mostly coloured blue or blue-green; copper and iron are the colouring agents detected; abundance of bubbles, silicate crystals and relics of unmelted material are responsible for their generally opaque appearance, together with the presence of weathering products. The characteristics of the body to glaze contact zone, together with the widespread presence of bubbles, would not rule out production by a single firing process. A few samples feature a peculiar gritty coating on one side of their surface; SEM images show that they are actually partially vitrified, and EDS data denote a rather heterogeneous composition. It seems possible that they result from mixing clay together with the frit used for glaze development. [source]


    ARCHAEOLOGICAL RESEARCH AT THE INSTITUTE OF NUCLEAR TECHNIQUES, BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS: SCHOLARLY ACHIEVEMENTS OF A PROSPEROUS LONG-TERM COLLABORATION

    ARCHAEOMETRY, Issue 2 2007
    M. BALLA
    The laboratory is part of a university institute with a nuclear reactor on the premises. NAA of archaeological materials started in the early 1980s, and has found continuous interest since then. Site-specific characteristics of the NAA procedure are the long irradiation and counting times, due to the relatively low neutron flux, the single comparator method of standardization and the use of reference materials for quality control. The main research interest focuses on provenance studies of potteries; 90% of the analysed samples are ceramic materials. Most of the projects concentrate on the investigation of pottery finds from Roman Pannonia, and from different archaeological sites in Israel. The Qumran pottery project is presented as a typical example. [source]


    A SCIENTIFIC INVESTIGATION ON THE PROVENANCE AND TECHNOLOGY OF A BLACK-FIGURE AMPHORA ATTRIBUTED TO THE PRIAM GROUP*

    ARCHAEOMETRY, Issue 1 2006
    P. MIRTI
    The restoration of a Greek black-figure amphora provided an opportunity to study the provenance and production technology of the vase. The composition of the ceramic body, determined by inductively coupled plasma optical emission spectroscopy (ICP,OES), matches that of Attic products. Investigation by X-ray diffraction and reflectance spectroscopy suggests a maximum firing temperature around 900°C and a body re-oxidation temperature around 800°C, respectively. The morphology and composition of black, red and dark red surface areas were studied by scanning electron microscopy and X-ray energy-dispersive analysis; the black areas show the features of a typical well-vitrified black gloss, while the red areas were most probably obtained by simple burnishing of the body; the dark red additions, on the other hand, are the likely result of a partial re-oxidation of a clay,ochre mixture. [source]


    THE TECHNOLOGY OF ,GLAZED' RESERVED SLIP WARE,A FINE CERAMIC OF THE HARAPPAN PERIOD*

    ARCHAEOMETRY, Issue 4 2005
    K. KRISHNAN
    ,Glazed' Reserved Slip Ware (RSW) is a high-quality glossy bichrome pottery of the Indus Valley civilization, and dates to the mature Harappan period (c. 2600,1900 bc). Scanning electron microscopy with energy-dispersive X-ray analysis indicates that the surface coat on RSW is composed of a pale grey vitrified clay slip, which overlies a black slip with significantly higher iron oxide. Hence the term ,sintered' Reserved Slip Ware is to be preferred. X-ray diffraction analysis indicates that both the pale and black slips contain hercynite, mullite and quartz, but observation by scanning electron microscopy shows that the black slips contain higher amounts of coarser-grained hercynite. The elemental data suggest that different clays were used to make the bodies and the slips. However, key element ratios are very close in associated black and pale slips. The grey slip may have been produced by elutriation of the fine, iron oxide-rich clay that was used to prepare the black slip. The pale grey slip was laid over the black and removed by combing to produce a bichrome effect, which evoked semi-precious materials such as agate. RSW was a specialist product that required significantly higher input skill and resources than the majority of Harappan clay-based ceramics. It is a further example of the range of sophisticated Harappan ceramic wares, which included faience, fired steatite and stoneware. [source]


    SHOULD MOLECULAR TECHNOLOGY REPLACE URINE CYTOLOGY?

    BJU INTERNATIONAL, Issue 10 2008
    Vijay K. Sangar
    No abstract is available for this article. [source]


    INVESTMENT IN HOSPITAL CARE TECHNOLOGY UNDER DIFFERENT PURCHASING RULES: A REAL OPTION APPROACH

    BULLETIN OF ECONOMIC RESEARCH, Issue 2 2008
    Rosella Levaggi
    I11; D81 ABSTRACT Quality of health care is the product of several factors as the literature has long recognized. In this paper we focus on the relationship between quality and investment in health technology by analysing the optimal investment decision in a new health care technology of a representative hospital that maximizes its surplus in an uncertain environment. The new technology allows the hospital to increase the quality level of the care provided, but the investment is irreversible. The paper uses the framework of the real option literature to show how the purchaser might influence the quality level by setting a quality-contingent long-term contract with the hospital. The investment in new technology is in fact best incentivated within a long-term contract where the number of treatments reimbursed depends on the level of investment made when the technology is new. In this way, asymmetry of information does not affect the outcome of the contract. In our model in fact the purchaser can verify the level of the investment only at the end of each period but the purchasing rule has an anticipating effect on the decision to invest. [source]


    Integration of General Sparse Matrix and Parallel Computing Technologies for Large,Scale Structural Analysis

    COMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 6 2002
    Hsien Hsieh, Shang
    Both general sparse matrix and parallel computing technologies are integrated in this study as a finite element solution of large,scale structural problems in a PC cluster environment. The general sparse matrix technique is first employed to reduce execution time and storage requirements for solving the simultaneous equilibrium equations in finite element analysis. To further reduce the time required for large,scale structural analyses, two parallel processing approaches for sharing computational workloads among collaborating processors are then investigated. One approach adopts a publicly available parallel equation solver, called SPOOLES, to directly solve the sparse finite element equations, while the other employs a parallel substructure method for the finite element solution. This work focuses more on integrating the general sparse matrix technique and the parallel substructure method for large,scale finite element solutions. Additionally, numerical studies have been conducted on several large,scale structural analyses using a PC cluster to investigate the effectiveness of the general sparse matrix and parallel computing technologies in reducing time and storage requirements in large,scale finite element structural analyses. [source]


    Technologies of the Voice: FM Radio, Telephone, and the Nepali Diaspora in Kathmandu

    CULTURAL ANTHROPOLOGY, Issue 3 2006
    Laura Kunreuther
    Through the public broadcast of intimate telephone conversations between Nepalis abroad and those in Kathmandu, the diaspora is made "present" in Kathmandu. On these commercial FM programs, the voice is viewed as a key sign of emotional directness, authenticity, and intimacy. Simultaneously, the figure of the voice has been central in discussions about the promises (and failures) of democracy and transparent governance. These two seemingly distinct formations of voice are mutually constitutive. Sentimental discourse about the voice reiterates modern neoliberal discourse about democracy and vice versa. Both are crucial to the formation of an urban Nepali subject in this political moment, which is deeply shaped by the figure of the diaspora. [source]


    Anthropology and the New Technologies of Communication

    CULTURAL ANTHROPOLOGY, Issue 3 2006
    Brian Keith Axel
    This article is a set of reflections on how a modern linguistic ideology of communication produces a fundamental misrecognition of the formation of the modern liberal subject as a naturally communicating subject. I explore the complex features of this misrecognition as a legacy of Cold War procedures of knowledge production about communication and technology to suggest that ethnographies of new technologies of communication unwittingly proliferate presumptions about the ontological integrity of the human prior to communication and prior to the advent of technologies of communication. This dilemma offers an alternative point of departure for the study of new technologies of communication in pursuit of a renewed, critical investigation into the circulation of modern cultural forms of intelligibility. [source]


    Evaluation of a single-platform microcapillary flow cytometer for enumeration of absolute CD4+ T-lymphocyte counts in HIV-1 infected Thai patients,,

    CYTOMETRY, Issue 5 2007
    Kovit Pattanapanyasat
    Abstract Background: Various assays are used to enumerate peripheral blood absolute CD4+ T-lymphocytes. Flow cytometry is considered the gold standard for this purpose. However, the high cost of available flow cytometers and monoclonal antibody reagents make it difficult to implement such methods in the resource-poor settings. In this study, we evaluated a cheaper, recently developed single-platform microcapillary cytometer for CD4+ T-lymphocyte enumeration, the personal cell analyzer (PCA), from Guava® Technologies. Methods: CD4+ and CD8+ T-lymphocyte counts in whole blood samples from 250 HIV-1 infected Thais were determined, using a two-color reagent kit and the Guava PCA, and compared with the results obtained with two reference microbead-based methods from Becton Dickinson Biosciences: the three-color TruCOUNTÔ tube method and the two-color FACSCountÔ method. Statistical correlations and agreements were determined using linear correlation and Bland,Altman analysis. Results: Absolute CD4+ T-lymphocyte counts obtained using the Guava PCA method highly correlated with those obtained using TruCOUNT method (R2 = 0.95, mean bias +13.1 cells/,l, limit of agreement [LOA] ,101.8 to +168.3 cells/,l). Absolute CD8+ T-lymphocyte counts obtained using the Guava PCA method also highly correlated with those obtained with the two reference methods (R2 = 0.92 and 0.88, respectively). Conclusion: This study shows that the enumeration of CD4+ T-lymphocytes using the Guava microcapillary cytometer PCA method performed well when compared with the two reference bead-based methods. However, like the two reference methods, this new method needs substantial technical expertise. © 2007 Clinical Cytometry Society. [source]


    Fractional Photothermolysis for Photoaging of Hands

    DERMATOLOGIC SURGERY, Issue 1 2008
    MING H. JIH MD
    BACKGROUND Laser treatment for photoaging of the hands should ideally address pigmentary alteration as well as associated skin roughness and wrinkling. Fractional resurfacing has been previously shown to effectively treat facial rhytids and dyschromia. OBJECTIVE We examined the effect of fractional resurfacing for photoaging of the hands. METHODS AND MATERIALS Ten patients (skin phototypes II to IV) with hand photodamage were randomized to receive five treatments with a 1,550-nm diode-pumped erbium fiber laser (Fraxel SR, Reliant Technologies) laser on either the right or left hand. Treatments were performed at settings of 8 to 9 mJ/microscopic treatment zone and density of 2,500 microscopic treatment zones/cm2. Subjective assessments by the patients and investigator were performed for skin roughness, wrinkling, and pigmentation using a 5-point scale. Skin biopsies were taken at baseline and at 1 and 3 months. RESULTS Patient subjective assessment and physician clinical assessment at 1 and 3 months revealed a mean 51% to 75% improvement in skin pigmentation and 25% to 50% improvement in skin roughness and wrinkling. Biopsies of the skin showed increased density of dermal collagen. Patients experienced transient erythema and edema and none had scarring or other adverse effects. LIMITATIONS This was a small study. CONCLUSION Fractional resurfacing appears to be an effective and safe treatment modality for correcting both the pigmentary and the textural aspects of photoaging of the hand. [source]


    Diagnosis of Nonmelanoma Skin Cancer/Keratinocyte Carcinoma: A Review of Diagnostic Accuracy of Nonmelanoma Skin Cancer Diagnostic Tests and Technologies

    DERMATOLOGIC SURGERY, Issue 10 2007
    METTE MOGENSEN MD
    BACKGROUND Nonmelanoma skin cancer (NMSC) is the most prevalent cancer in the light-skinned population. Noninvasive treatment is increasingly used for NMSC patients with superficial lesions, making the development of noninvasive diagnostic technologies highly relevant. OBJECTIVE The scope of this review is to present data on the current state-of-the-art diagnostic methods for keratinocyte carcinoma: basal cell carcinoma, squamous cell carcinoma, and actinic keratosis. METHODS AND MATERIALS MEDLINE, BIOSIS, and EMBASE searches on NMSC and physical and clinical examination, biopsy, molecular marker, ultrasonography, Doppler, optical coherence tomography, dermoscopy, spectroscopy, fluorescence imaging, confocal microscopy, positron emission tomography, computed tomography, magnetic resonance imaging, terahertz imaging, electrical impedance and sensitivity, specificity, and diagnostic accuracy. RESULTS State-of-the-art diagnostic research has been limited in this field, but encouraging results from the reviewed diagnostic trials have suggested a high diagnostic accuracy for many of the technologies. Most of the studies, however, were pilot or small studies and the results would need to be validated in larger trials. CONCLUSIONS Some of these new imaging technologies have the capability of providing new, three-dimensional in vivo, in situ understanding of NMSC development over time. Some of the new technologies described here have the potential to make it from the bench to the clinic. [source]


    The Treatment of Melasma with Fractional Photothermolysis: A Pilot Study

    DERMATOLOGIC SURGERY, Issue 12 2005
    Cameron K. Rokhsar MD
    Background. Melasma is a common pigmentary disorder that remains resistant to available therapies. Facial resurfacing with the pulsed CO2 laser has been reported successful but requires significant downtime, and there is a risk of adverse sequelae. Objective. To determine if melasma will respond to a new treatment paradigm, fractional resurfacing. Methods. Ten female patients (Fitzpatrick skin types III,V) who were unresponsive to previous treatment were treated at 1- to 2-week intervals with the Fraxel laser (Reliant Technologies, Palo Alto, CA, USA). Wavelengths of 1,535 and 1,550 nm were both used, and 6 to 12 mJ per microthermal zone with 2,000 to 3,500 mtz/cm2 were the treatment parameters. Four to six treatment sessions were performed. Responses were evaluated according to the percentage of lightening of original pigmentation. Two physicians evaluated the photographs, and each patient evaluated her own response. Results. The physician evaluation was that 60% of patients achieved 75 to 100% clearing and 30% had less than 25% improvement. The patients' evaluations agreed, except for one patient, who graded herself as 50 to 75% improved as opposed to the physician grading of over 75%. There was one patient with postinflammatory hyperpigmentation and no patient with hypopigmentation. No downtime was necessary for wound healing. Conclusions. Fractional resurfacing affords a new treatment algorithm for the treatment of melasma that combines decreased risk and downtime with significant efficacy. This treatment modality deserves further exploration to maximize benefits. RELIANT technologies LOANED THE FRAXEL LASER FOR THE STUDY. RICHARD E. FITZPATRICK, MD, IS A PAID CONSULTANT FOR RELIANT AND A STOCKHOLDER. [source]


    Information and Communication Technologies for Direct Poverty Alleviation: Costs and Benefits

    DEVELOPMENT POLICY REVIEW, Issue 2 2002
    Charles Kenny
    Information and communications technologies (ICTs) are powerful tools for empowerment and income generation in developing countries. The cost-effectiveness of different ICTs does vary between developed and less developed countries, however. This article reviews the potential efficacy of radio, telephony and the Internet as tools of direct poverty alleviation in the latter. While the requirements for their successful utilisation make radio and telephone far more suitable technologies for the poor, traditional ICTs can act as a sustainable intermediary for them to gain indirect access to the power of the Internet. Governments should concentrate on opening up private and community provision of broadcasting and widening access to telephone services, so that they can effectively play this intermediary role. [source]


    An Update on Emerging Echocardiographic Technologies

    ECHOCARDIOGRAPHY, Issue 7 2003
    Roberto M. Lang M.D.
    No abstract is available for this article. [source]


    Fixation of heavy contaminants of a dirty bomb attack: Studies with uranium and metal simulants

    ENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY, Issue 1 2007
    Thomas L. McGehee
    Abstract Asphalt emulsions were evaluated as a means to immobilize radiological contaminants deposited on urban surfaces after a dirty bomb attack. Contaminated surfaces would be sprayed with thin coatings of asphalt emulsion to encapsulate the radioactive particles until the site can be safely remediated. This research investigated applications of an asphalt emulsion (Topein C, Encapco Technologies, LLC, Napa, CA) to treat (zero-valent) iron, lead, and uranium powders on various building material surfaces. Initial studies found that some of the building materials (limestone, concrete, and metal) reacted with the emulsion producing gas bubbles, which formed 0.001 to 1 cm vesicles in the cured asphalt emulsion. These vesicles, however, did not expose the building material surface, and the reaction appeared to aid in the setting of the emulsion. Powdered lead did not react with the asphalt emulsion, but iron powder and uranium did. Iron powder and the emulsion formed vesicles up to 0.5 mm (but not exposing the building material surface), while the uranium (U3O8) had a moderate reaction when compared with to the lead and iron powders. Scanning electron micrographs showed that the lead powder formed nonreactive layers adjacent to the concrete surface while iron particles were evenly distributed in the asphalt matrix due to the reaction with the asphalt, indicating that the physical and chemical reactions between the iron metal particles, asphalt, and concrete affected particle distribution in the asphalt matrix. A vertical operation sediment tube was used to determine the flowing shear stress durability of the asphalt/metal/substrate complex. The asphalt treatment with iron had no loss at the shear range tested (0.1,2.5 Pa), while the asphalt stabilized powdered lead lost 8% asphalt and lead at 2.5 Pa mean shear stress applied for 5 h. The chemical reaction between asphalt emulsion and iron increased the resistance of the asphalt/metal/substrate complex to shear when compared with lead. Some hydrogen was formed in reactions with iron, but the amount formed was well below the lower flammability limit. Treatment of uranium indicated that the emulsion was effective at reducing leaching of the uranium 10 fold. These experiments indicate that asphalt emulsions may be a viable means for containing metallic or dense radiological contaminants on common building materials. © 2007 American Institute of Chemical Engineers Environ Prog 26:94,103, 2007 [source]