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Technical Equipment (technical + equipment)
Selected AbstractsTechnical equipment for assessment of dental pulp statusENDODONTIC TOPICS, Issue 1 2004Thomas R. Pitt Ford Assessment of dental pulp status is normally undertaken using thermal or electrical tests that indicate the functioning of A, nerve fibers. The tests are quick and usually reliable, although nothing is absolute. Newer tests have involved assessment of blood flow, and of these laser Doppler flowmetry has been the most widely used and beneficial to patients particularly after traumatic injury. The high cost of flowmeters and the time-consuming procedure have limited uptake. [source] Managing the Co-operation,Competition Dilemma in R&D Alliances: A Multiple Case Study in the Advanced Materials IndustryCREATIVITY AND INNOVATION MANAGEMENT, Issue 1 2010Dries Faems Generating value in R&D alliances requires intensive and fine-grained interaction between collaborating partners. At the same time, more intensive co-operation increases the risk of competitive abuse of the R&D alliance by one or more partners. In this study, we explore how managers address the fundamental tension between the need for co-operation and the risk of competition, using an in-depth case study of five R&D alliances in the advanced materials industry. Based on our data, we identify two relational strategies to enhance co-operation between engineers of different partners (i.e., adopting boundary-spanning activities and installing similar technical equipment) and three structural strategies to mitigate the risk of such intensified co-operation (i.e., definition of partner-specific task domains, definition of partner-specific knowledge domains and definition of partner-specific commercial domains). In addition, we find that partners tend to use particular combinations of such relational and structural strategies at different stages of the alliance life-cycle to address the co-operation,competition dilemma. [source] Treatment of erythema multiforme, Stevens,Johnson Syndrome, and toxic epidermal necrolysisDERMATOLOGIC THERAPY, Issue 4 2002Klemens Rappersberger The "erythema multiforme disease spectrum" comprises four distinct, severe, clinical subvariants: (1) bullous erythema multiforme (bullous-EM), (2) Stevens,Johnson syndrome (SJS), (3) SJS,toxic epidermal necrolysis (TEN)-overlap syndrome, and (4) TEN. These diseases are closely related to severe mucocutaneous intolerance reactions that are mostly elicited by drugs/drug metabolites and associated with a high mortality rate. Old age and area of detached skin negatively influence the course of disease, and early withdrawal of causative drugs with short half-life is a positive prognostic factor. Therapeutic management represents a multidisciplinary challenge for colleagues from various specialities including specialized nurses and usually can be performed at a dermatologic ward unless technical equipment of an intensive care unit is needed. Topical therapy with biologic and (semi-)synthetic dressings is aimed at early re-epithelialization and the prevention of scarring, synechia formation, and infection. Systemic treatment includes antibiotics, fluid and electrolyte replacement, protein preparations and blood products, etc. Various anti-inflammatory and immunosuppressive treatment regimens with corticosteroids, cyclosporine A, cyclophosphamide, plasmapheresis have been considered to halt ongoing immunologic pathomechanisms, and some of these have shown significant efficacy. However, because we lack formal clinical trials, none of these regimens can be definitively proposed as a therapy of choice in any of the severe clinical variants of the EM spectrum. [source] Use of image analysis techniques for objective quantification of the efficacy of different hair removal methodsINTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Issue 2 2007S. Bielfeldt In the field of consumer-used cosmetics for hair removal and hair growth reduction, there is a need for improved quantitative methods to enable the evaluation of efficacy and claim support. Optimized study designs and investigated endpoints are lacking to compare the efficacy of standard methods, like shaving or plucking, with new methods and products, such as depilating instruments or hair-growth-reducing cosmetics. Non-invasive image analysis, using a high-performance microscope combined with an optimized image analysis tool, was investigated to assess hair growth. In one step, high-resolution macrophotographs of the legs of female volunteers after shaving and plucking with cold wax were compared to observe short-term hair regrowth. In a second step, images obtained after plucking with cold wax were taken over a long-term period to assess the time, after which depilated hairs reappeared on the skin surface. Using image analysis, parameters like hair length, hair width, and hair projection area were investigated. The projection area was found to be the parameter most independent of possible image artifacts such as irregularities in skin or low contrast due to hair color. Therefore, the hair projection area was the most appropriate parameter to determine the time of hair regrowth. This point of time is suitable to assess the efficacy of different hair removal methods or hair growth reduction treatments by comparing the endpoint after use of the hair removal method to be investigated to the endpoint after simple shaving. The closeness of hair removal and visible signs of skin irritation can be assessed as additional quantitative parameters from the same images. Discomfort and pain rating by the volunteers complete the set of parameters, which are required to benchmark a new hair removal method or hair-growth-reduction treatment. Image analysis combined with high-resolution imaging techniques is a powerful tool to objectively assess parameters like hair length, hair width, and projection area. To achieve reliable data and to reduce well known image-analysis artifacts, it was important to optimize the technical equipment for use on human skin and to improve image analysis by adaptation of the image-processing procedure to the different skin characteristics of individuals, like skin color, hair color, and skin structure. [source] Effective Safety Management: a Case Study in the Chemical IndustryQUALITY AND RELIABILITY ENGINEERING INTERNATIONAL, Issue 4 2004P. J. M. Sonnemans Abstract A major non-trivial problem within the area of industrial safety management today is to analyse, next to the safety impact of the technical equipment, the safety impact of a ,business process' as currently required by regulation and safety standards. This paper describes a case study of a pesticide company struggling with the question of how to improve the safety of their operational process further and at the same time also improve the reliability of their operational process. According to the literature ,control of the business process' is the keyword to improve the safety and reliability ,performance' of a company. A formal control model is proposed together with a classification system (using maturity levels) to analyse and qualify business processes with respect to their impact on process safety. This method has been applied in a case study where it resulted in a model of a business process. Using the model it was possible to classify the business process control system used and to identify related improvement opportunities. The proposed method showed that, in contrast to the company's perception, it was not the production department that was responsible for most of the problems but the peripheral processes relating to the production department. The interaction between departments caused not only potential safety problems, but also caused system reliability problems. For the company it was demonstrated that the interdependency of the (different activities in the-) operational process is an essential element preventing further improvement if not addressed properly. Copyright © 2004 John Wiley & Sons, Ltd. [source] Visualization of protein interactions in living plant cells using bimolecular fluorescence complementationTHE PLANT JOURNAL, Issue 3 2004Michael Walter Summary Dynamic networks of protein,protein interactions regulate numerous cellular processes and determine the ability to respond appropriately to environmental stimuli. However, the investigation of protein complex formation in living plant cells by methods such as fluorescence resonance energy transfer has remained experimentally difficult, time consuming and requires sophisticated technical equipment. Here, we report the implementation of a bimolecular fluorescence complementation (BiFC) technique for visualization of protein,protein interactions in plant cells. This approach relies on the formation of a fluorescent complex by two non-fluorescent fragments of the yellow fluorescent protein brought together by association of interacting proteins fused to these fragments (Hu et al., 2002). To enable BiFC analyses in plant cells, we generated different complementary sets of expression vectors, which enable protein interaction studies in transiently or stably transformed cells. These vectors were used to investigate and visualize homodimerization of the basic leucine zipper (bZIP) transcription factor bZIP63 and the zinc finger protein lesion simulating disease 1 (LSD1) from Arabidopsis as well as the dimer formation of the tobacco 14-3-3 protein T14-3c. The interaction analyses of these model proteins established the feasibility of BiFC analyses for efficient visualization of structurally distinct proteins in different cellular compartments. Our investigations revealed a remarkable signal fluorescence intensity of interacting protein complexes as well as a high reproducibility and technical simplicity of the method in different plant systems. Consequently, the BiFC approach should significantly facilitate the visualization of the subcellular sites of protein interactions under conditions that closely reflect the normal physiological environment. [source] Von der Werfthalle des CargoLifter zum Tropical Island Resort: Klima- und Energiekonzept für den weltweit größten überdachten tropischen FreizeitparkBAUPHYSIK, Issue 6 2004Heinrich Post Dr.-Ing. Für die Umplanung der ehemaligen CargoLifter-Halle zum "Tropical Island Resort" werden die wesentlichen Schritte des Climaengineering im Rahmen der Vorplanung beschrieben. Zunächst werden die Klimakonzepte für den winterlichen- und sommerlichen Betriebsfall vorgestellt, die sich nach der Analyse von Baukörper, Nutzungsanforderungen und Außenklima und der Optimierung der technischen Anlagenparameter im Rahmen von komplexen, dynamischen Gebäude- und Raumströmungssimulationen ergaben. Abschließend wird das Energiekonzept des Tropical Island Resort beschrieben. From CargoLifter hangar to Tropical Island Resort ndash; climate and energy design for the world's largest covered tropical amusement park. For the redesign of the former hangar of CargoLifter into "Tropical Island Resort" the basic steps of climate engineering during preliminary planning stage are specified. First of all the indoor climate concepts for winter and summer conditions are presented, resulting from complex, dynamical building and airfluid simulations regarding building analysis, usage demands, outdoor climate and optimization of technical equipment. Finaly energie strategy of Tropical Island Resort is characterized. [source] Self-report of physical symptoms associated with using mobile phones and other electrical devicesBIOELECTROMAGNETICS, Issue 6 2009Leena H. Korpinen Abstract The aim of our work was to study the working-age population's self-reported physical symptoms associated with using mobile phones and other electrical devices. A qualitative method was applied using an open-ended question in a questionnaire, which included questions about the possible influence of new technical equipment on health. We then created subgroups of respondents for different self-reported symptoms associated with mobile phones and other electrical devices. The research questions were: (1) how the respondents described physical symptoms associated with using mobile phones and other electrical devices and (2) how the answers can be classified into subgroups based on symptoms or devices. We identified the following categories: (1) respondents with different self-reported symptoms which they associated with using mobile phones (headache, earache, or warmth sensations), (2) respondents who had skin symptoms when they stayed in front of a computer screen, (3) respondents who mentioned physical symptoms associated with using mobile phones and other electrical devices. Total prevalence of self-reported physical symptoms associated with using mobile phones and other electrical devices (categories 1 and 2) was 0.7%. In the future it will be possible to obtain new knowledge of these topics by using qualitative methods. Bioelectromagnetics 30:431,437, 2009. © 2009 Wiley-Liss, Inc. [source] | ||||||||||||||||