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System Works (system + work)
Selected AbstractsCONFLICT OF INTEREST DECLARATIONS: COULD A ,TRAFFIC LIGHT' SYSTEM WORK?ADDICTION, Issue 11 2009ROBERT WEST No abstract is available for this article. [source] Just how does the cII selection system work in MutaÔMouse?ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 4 2001Roy R. Swiger Abstract The lambda CII protein is an essential component in the lytic vs. lysogeny decision a bacteriophage makes upon infection of a host at low temperatures. The protein interacts with numerous phage promoters modulating the expression of the CI repressor, thus providing the mechanism for lysogenization soon after infection. The Big Blue® and MutaÔMouse are two widely used in vivo mutational model systems. The assays rely on retrievable lambda-based transgenes housing mutational targets (lacI or lacZ, respectively). The transgenes provide an elegant vehicle for the quantification of mutations sustained in virtually any tissue of the rodent. The use of the bacteriophage cII locus as an alternative, or additional mutational target for use with the Big Blue® rodent system was first reported by Jakubczak et al. ([1996]: Proc Natl Acad Sci USA 93:9073,9078). More recently, this selection assay has been applied successfully to the MutaÔMouse (Swiger et al. [1999]: Environ Mol Mutagen 33:201,207). The use of an Hfl bacterial strain and low temperature allows the determination of mutations sustained at the cII locus in either system, with high fidelity. The cII selection assay in the Big Blue® relies on the presence of the lambda repressor protein CI. In contrast, the recombinant construct used to make the MutaÔMouse transgene lacks functional CI protein. Nevertheless, we report an excellent system for quantifying mutations at the cII locus in MutaÔMouse. Just how does cII selection work in the MutaÔMouse? Written in the context of lambda recombinant genetics, this paper explores the question further. Environ. Mol. Mutagen. 37:290,296, 2001 © 2001 Wiley-Liss, Inc. [source] Een-Gonyama Gonyama!: Zulu Origins of the Boy Scout Movement and the Africanisation of Imperial BritainPARLIAMENTARY HISTORY, Issue 1 2008TIMOTHY PARSONS British imperialists in the late 19th century denigrated non-western cultures in rationalising the partition of Africa, but they also had to assimilate African values and traditions to make the imperial system work. The partisans of empire also romanticised non-western cultures to convince the British public to support the imperial enterprise. In doing so, they introduced significant African and Asian elements into British popular culture, thereby refuting the assumption that the empire had little influence on the historical development of metropolitan Britain. Robert Baden-Powell conceived of the Boy Scout movement as a cure for the social instability and potential military weakness of Edwardian Britain. Influenced profoundly by his service as a colonial military officer, Africa loomed large in Baden-Powell's imagination. He was particularly taken with the Zulu. King Cetshwayo's crushing defeat of the British army at Isandhlawana in 1879 fixed their reputation as a ,martial tribe' in the imagination of the British public. Baden-Powell romanticised the Zulus' discipline, and courage, and adapted many of their cultural institutions to scouting. Baden-Powell's appropriation and reinterpretation of African culture illustrates the influence of subject peoples of the empire on metropolitan British politics and society. Scouting's romanticised trappings of African culture captured the imagination of tens of thousands of Edwardian boys and helped make Baden-Powell's organisation the premier uniformed youth movement in Britain. Although confident that they were superior to their African subjects, British politicians, educators, and social reformers agreed with Baden-Powell that ,tribal' Africans preserved many of the manly virtues that had been wiped by the industrial age. [source] Between spin and reality: examining disclosure practices in three African countriesPUBLIC ADMINISTRATION & DEVELOPMENT, Issue 3 2007George A. LarbiArticle first published online: 28 JUN 200 Abstract The declaration of assets and liabilities represents a growing trend in the avoidance and resolution of conflict of interest and has become a part of an integrated strategy to control corruption. This article reviews practices in Ghana, Tanzania and Uganda by addressing questions of who must declare, what must be declared, where to declare and how often to declare. It argues that like all the other mechanisms for controlling corruption, its efficacy depends on enforcement and compliance. The three cases reviewed suggest that there is a significant gap between the rhetoric of declaration and the reality of effective monitoring and compliance to make the system work to ensure transparency and public trust. Copyright © 2007 John Wiley & Sons, Ltd. [source] Road Infrastructure Data Acquisition Using a Vehicle-Based Mobile Mapping SystemCOMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 5 2006Gi-Hong Kim The mobile mapping system that integrates the global positioning system (GPS), the inertial navigation system (INS), and digital cameras has been developed to collect data on position and attributes of road infrastructure. The vehicle-based mobile mapping system works by having the GPS and INS record the position and attitude data, and digital cameras take road images. The stereovision system can determine the position of objects that are visible on the image pair in the global coordinate system with GPS and INS data. As field data acquisition is a very expensive task, a mobile mapping system offers a greatly improved solution. In this study, we successfully created a road infrastructure map with mobile mapping technology and proposed automatic algorithms for detecting and identifying road signs from road images. The proposed detection algorithm includes line and color region extraction processes and uses the Hopfield neural networks. The identification algorithm uses seven invariant moments and parameters that present geometric characteristics. With this combined method, we could successfully detect and identify road signs. [source] The allocation of prestigious positions in organizational science: accumulative advantage, sponsored mobility, and contest mobilityJOURNAL OF ORGANIZATIONAL BEHAVIOR, Issue 5 2005C. Chet Miller More than 200 freshly minted doctoral graduates enter the field of organization science every year. A non-trivial number of existing faculty members move from one university to another every year, while other organization science faculty leave academia to enter retirement, consulting, or industry. Despite the importance of this large, complex system of entries and exits, few attempts have been made to explicitly understand how the system works. Drawing upon sociology of science and careers research, we studied the underlying form of the position allocation system by focusing on the relative importance of research success and prior affiliations as antecedents of movement and stability across positions. We used three theoretical models: accumulative advantage, sponsored mobility, and contest mobility. Tracking hundreds of faculty members for 16 years post doctorate, we find a downward cascading of affiliation prestige over time that affects people more dramatically and quickly than we expected, especially women. Accumulative advantage, the most predictive of our models, does help to maintain relative but not absolute prestige, at least until its effects wane in later years of the career. These findings are relevant to scholars interested in the sociology of science, organization scholars interested in the underlying dynamics of their discipline, and individuals making career choices. Copyright © 2005 John Wiley & Sons, Ltd. [source] Serotonin in the rabbit ileum: Localization, uptake, and effect on motilityTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 2 2003Viktória Dénes Abstract Repeated experiments to localise serotonin in the myenteric plexus of rabbit ileum failed. After preincubation in serotonin (10,5 M), an extensive varicose fibre system was detected by immunocytochemical methods. Stained fibres left the myenteric plexus and ran to the muscle layers. Labelled cell bodies could not be found, even after pretreatment with colchicine or pargyline. Application of reserpine (10,5 M) and fluoxetine (10,5 M) prevented serotonin uptake. Antisera against tryptophan hydroxylase revealed a rich fibre system, including those processes that entered the tertiary plexus. These fibres were able to accumulate serotonin, but again the cell bodies could not be detected. Serotonin caused concentration-dependent contraction in the longitudinal muscle layer of the rabbit ileum. Pretreatment with tetrodotoxin strongly reduced the effect of serotonin. Preapplication of atropine caused a slight decrease of response evoked by serotonin. Combined administration of tetrodotoxin and atropine significantly reduced the responses to serotonin, but did not abolish them. At the same time, agonists of 5-HT2 and 5-HT4 receptors caused concentration-dependent contractions. Our studies show that: 1) Without pretreatment, serotonin cannot be detected in the myenteric plexus of rabbit ileum. 2) An extensive uptake system works in this plexus. If released from myenteric nerve fibres, serotonin may evoke contractions in indirect and direct ways. 3) There may be an extrinsic serotoninergic innervation from the mesenteric ganglia. 4) Serotonin exerts its effect through 5-HT2 and 5-HT4 receptors on smooth muscle cells and nerve elements. Anat Rec Part A 271A:368,376, 2003. © 2003 Wiley-Liss, Inc. [source] Integrated control method for a fuel cell hybrid systemASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING, Issue 1 2009Hongwen He Abstract To apply a fuel cell engine (FCE) on a hybrid electric vehicle, an integrated control method is put forward according to the driving characteristics of the vehicle. The FCE's output power is self-regulated to minimize hydrogen consumption and at the same time to meet the driving power requirement of the vehicle. For the difference of the power output dynamics, the actual power difference between the FCE and the vehicle load is compensated passively by a secondary power battery pack. Vehicle experiments show that the fuel cell hybrid system works well without any adverse influence on the vehicle power performance. Copyright © 2008 Curtin University of Technology and John Wiley & Sons, Ltd. [source] | |||||||||||||