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Study Addressing (study + addressing)

Distribution by Scientific Domains

Medical Sciences	75%

Selected Abstracts

A comparison of mothers' and fathers' experiences of the attachment process in a neonatal intensive care unit

JOURNAL OF CLINICAL NURSING, Issue 6 2008
Liv Fegran RN
Aim., To compare mothers' and fathers' individual views and experiences of the attachment process in a neonatal intensive care unit within the first week after a premature birth. Background., The attachment between parents and children is a precursor to the consolidation of parenting skills, the growth and development of the infant and the establishment of a bond between parent and child. Premature birth and the resultant hospitalization disrupt the normal attachment process between parent and child. Most of the litteraure on attachment theory focuses on the mother,child connection and is being criticised for regarding the father's role as supportive and peripheral. Methods., The design of this study was descriptive with a hermeneutic approach. Twelve parents (six mothers and six fathers) in a 13-bed neonatal intensive care unit in a Norwegian regional hospital participated in a field study addressing the encounter between parents and nurses. This paper is based on the semi-structured interviews with the parents at discharge. Results., The interview analysis revealed two main categories. (a) Taken by surprise: For mothers, the premature birth created a feeling of powerlessness and they experienced the immediate postnatal period as surreal and strange. The fathers experienced the birth as a shock, but were ready to be involved immediately. (b) Building a relationship: Mothers experienced a need to regain the temporarily lost relationship with their child, whereas the fathers experienced the beginning of a new relationship. Conclusion., Comparing parents' experiences of the attachment process within the first days after a premature birth reveals a striking contrast between the mother's experience of surrealism and the father's ability to be involved immediately after birth. Relevance to clinical practice., Parents' of premature children's different starting points should be acknowledged as professionals encourage parents to have early skin-to-skin contact with their premature infant. [source]

Student transfer between Oregon community colleges and Oregon University system institutions

NEW DIRECTIONS FOR COMMUNITY COLLEGES, Issue 114 2001
James C. Arnold
This chapter highlights findings from a recent study addressing the issues of students who transfer between community colleges and public universities in the state of Oregon. Implications for policymakers and institutional practitioners are discussed. [source]

Anonymous non-response analysis in the ABCD cohort study enabled by probabilistic record linkage

PAEDIATRIC & PERINATAL EPIDEMIOLOGY, Issue 3 2009
M. Tromp
Summary Selective non-response is an important threat to study validity as it can lead to selection bias. The Amsterdam Born Children and their Development study (ABCD-study) is a large cohort study addressing the relationship between life style, psychological conditions, nutrition and sociodemographic background of pregnant women and their children's health. Possible selective non-response and selection bias in the ABCD-study were analysed using national perinatal registry data. ABCD-study data were linked with national perinatal registry data by probabilistic medical record linkage techniques. Differences in the prevalence of relevant risk factors (sociodemographic and care-related factors) and birth outcomes between respondents and non-respondents were tested using Pearson chi-squared tests. Selection bias (i.e. bias in the association between risk factors and specific outcomes) was analysed by regression analysis with and without adjustment for participation status. The ABCD non-respondents were significantly younger, more often non-western, and more often multiparae. Non-respondents entered antenatal care later, were more often under supervision of an obstetrician and had a spontaneous delivery more often. Non-response however, was not significantly associated with preterm birth (odds ratio 1.10; 95% CI 0.93, 1.29) or low birthweight (odds ratio 1.16; 95% CI 0.98, 1.37) after adjustment for sociodemographic risk factors. The associations found between risk factors and adverse pregnancy outcomes were similar for respondents and non-respondents. Anonymised record linkage of cohort study data with national registry data indicated that selective non-response was present in the ABCD-study, but selection bias was acceptably low and did not influence the main study questions. [source]

The pharmacodynamic equivalence of levothyroxine and liothyronine: a randomized, double blind, cross-over study in thyroidectomized patients

CLINICAL ENDOCRINOLOGY, Issue 5 2010
Francesco S. Celi
Summary Context, The substitution of liothyronine (L-T3) for levothyroxine (L-T4) is commonly employed during thyroid hormone (TH) withdrawal in preparation for diagnostic and therapeutic interventions on thyroid cancer patients. Presently, only limited data are available on the L-T3 for L-T4 therapeutic substitution. Objective, To characterize the pharmcodynamic equivalence of L-T3 and L-T4. Design, Randomized, double-blind, cross-over intervention study. Setting, NIH clinical center. Patients, Ten thyroidectomized patients. Interventions, Study participants were treated with L-T3 or L-T4 with a target TSH , 0·5 , 1·5 mU/l for at least 30 days before undergoing inpatient testing. Following testing, subjects crossed-over according to the same scheme. Main outcome measures, Area under the serum concentration,time curve of TSH from 0 to 60 min (AUC0,60) and peak TSH serum concentration (Cmax) following thyrotropin-releasing hormone (TRH) stimulation test, total L-T4 and L-T3 dose (mcg/kg), and L-T4/L-T3 ratio. Results, No difference was observed for time 0 TSH values between L-T3 and L-T4 replacement phases (1·48 ± 0·77 vs. 1·21 ± 0·62 mU/l, P = 0·293) at average daily doses of 40·3 ± 11·3 mcg L-T3 and 115·2 ± 38·5 mcg L-T4, L-T3: L-T4 ratio 0·36 ± 0·06. TRH stimulation test resulted in similar L-T3 vs. L-T4 TSH responses with AUC0,60 of 326·1 (95% CI 232·6,457·1) and 247·1 (95% CI 153·8,397·1) mU* min/l (P = 0·285); and Cmax of 6·83 (95% CI 4·88,9·55) and 5·23 (95% CI 3·31,8·3) mU/l (P = 0·383). Conclusions, This is the first study addressing the equivalency between L-T3 and L-T4 therapy measured by baseline and TRH-stimulated TSH. The therapeutic substitution of L-T3 for L-T4 was achieved at approximately 1:3 ratio. [source]