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Studies Pertaining (studies + pertaining)

Distribution by Scientific Domains

Medical Sciences	60%

Selected Abstracts

Disease, deficit or denial?

ACTA PSYCHIATRICA SCANDINAVICA, Issue 1 2005
Models of poor insight in psychosis
Objective:, To examine the evidence for the three kinds of aetiological model that dominate the current literature on poor insight in psychosis: clinical models, the neuropsychological model, and the psychological denial model. Method:, Studies pertaining to one or more of these aetiological models were identified, reviewed and critically evaluated. Results:, There is little support for clinical models, partly because they lack testable hypotheses. Several studies reveal a positive relationship between insight and executive function, which may be related to frontal lobe dysfunction. However, the extent to which this relationship is specific and independent of general cognitive impairment remains unclear. There is tentative evidence to support the psychological denial model. Recent data combining the latter two approaches suggest that multiple factors contribute to poor insight. Conclusion:, Integration of different aetiological models is necessary for a fuller understanding of insight in psychosis. Future research should assess multiple aetiological mechanisms in single investigations. [source]

Enhancing the Growth of Natural Eyelashes: The Mechanism of Bimatoprost-Induced Eyelash Growth

DERMATOLOGIC SURGERY, Issue 9 2010
2Article first published online: 2 APR 2010, JOEL L. COHEN MD
BACKGROUND Many women desire prominent eyelashes. In December 2008, bimatoprost ophthalmic solution 0.03% was approved for the treatment of hypotrichosis of the eyelashes in the United States. OBJECTIVE To review eyelash physiology and the proposed mechanisms by which the topical pros-tamide product bimatoprost enhances eyelash growth. METHODS AND MATERIALS Clinical and preclinical studies pertaining to the efficacy, safety, and mechanisms of action of bimatoprost are presented. RESULTS Treatment with bimatoprost increases the percentage of eyelash follicles in anagen at any one time. This probably accounts for its ability to lengthen lashes. Bimatoprost-induced stimulation of melanogenesis appears to result in darker lashes and, at the same time, appears to increase the size of the dermal papilla and hair bulb, affecting lash thickness and fullness. Such effects, largely demonstrated in animal studies, are consistent with the results of a recent Food and Drug Administration phase III clinical trial. The favorable safety profile of bimatoprost in human subjects is probably secondary to the limited exposure of ocular tissues resulting from topical application at the base of the upper lashes. CONCLUSION By influencing the eyelash hair cycle and follicles, bimatoprost ophthalmic solution 0.03% is a safe and effective means of enhancing eyelash growth. Dr. Cohen has served as a consultant and clinical trial participant for Allergan, Inc. [source]

Pricing of Forward and Futures Contracts

JOURNAL OF ECONOMIC SURVEYS, Issue 2 2000
Ying-Foon Chow
There has long been substantial interest in understanding the relative pricing of forward and futures contracts. This has led to the development of two standard theories of forward and futures pricing, namely, the Cost-of-Carry and the Risk Premium (or Unbiased Expectations) hypotheses. These studies have modelled the relationship between spot and forward/futures prices either through a no-arbitrage condition or a general equilibrium setting. Relatively few studies in this area have considered the impact of stochastic trends in the data. With the emergence of non-stationarity and cointegration in recent years, more sophisticated models of futures/forward prices have been specified. This paper surveys the significant contributions made to the literature on the pricing of forward/futures contracts, and examines recent empirical studies pertaining to the estimation and testing of univariate and systems models of futures pricing. [source]

Dimensions of quality of life and psychosocial variables most salient to colorectal cancer patients

PSYCHO-ONCOLOGY, Issue 1 2006
Jeff Dunn
Abstract Colorectal cancer is one of the most common invasive cancers, and is responsible for considerable physical and psychosocial morbidity. Understanding the quality of life experienced by colorectal cancer patients is essential for evaluating the full impact of the disease on individuals, their families and their communities. Patient perspective is essential in establishing a proper understanding of the quality of life of colorectal cancer patients. Despite this, few studies have employed a qualitative methodology to explore quality of life issues for colorectal cancer patients. A review of the literature identified only seven qualitative studies pertaining to quality of life issues for colorectal cancer patients, a surprising finding given the prevalence of this cancer. Accordingly, this study sought to build on the findings of previous qualitative research by providing descriptive data on the quality of life and psychosocial variables most salient to colorectal cancer patients. Six core themes emerged from interview and focus group data: Satisfaction with diagnosis and treatment; support (including information provision); quality of life; benefits of diagnosis; making sense of the cancer experience; and coping strategies. The information derived from this study will help inform the development of supportive care services to address the needs of the increasing number of people diagnosed with colorectal cancer. Copyright © 2005 John Wiley & Sons, Ltd. [source]

Research Review: Sibling placement in foster care: a review of the evidence

CHILD & FAMILY SOCIAL WORK, Issue 4 2007
Karla Washington
ABSTRACT This research review was undertaken to explore the current evidence pertaining to sibling placement in the foster care system. The review specifically addresses the following questions: (1) Which theories inform research on siblings in foster care? (2) Which designs and methodology are used to study brothers and sisters in out of home placement? (3) How do researchers define ,siblings' when investigating child placement? and (4) What are the findings of studies pertaining to siblings in the foster care system? This review suggests that incorporation of theory into research regarding siblings in foster care is quite limited. Additionally, few studies clearly state how siblings were identified and defined. A major strength of the research, however, is the diversity of design and methodology used. Overall, the evidence presented in this review strongly supports keeping sibling groups intact unless there is a compelling reason for separate placements. [source]