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Specific Predictions (specific + prediction)
Selected AbstractsWinds from massive stars: implications for the afterglows of , -ray burstsMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 3 2001Enrico Ramirez-Ruiz Recent observations suggest that long-duration , -ray bursts (GRBs) and their afterglows are produced by highly relativistic jets emitted in core-collapse explosions. The pre-explosive ambient medium provides a natural test for the most likely progenitors of GRBs. Those stars that shed their envelopes most readily have short jet crossing times and are more likely to produce a GRB. We construct a simple computational scheme to explore the expected contribution of the presupernova ejecta of single Wolf,Rayet (WR) stars to the circumstellar environment. Using detailed stellar tracks for the evolution of massive stars, we discuss the effects that the initial main-sequence mass, metallicity, rotation and membership in a binary system have on the ambient medium. We extend the theory of GRB afterglows in winds to consider the effect of the relativistic fireball propagating through the WR ejecta. Specific predictions are made for the interaction of the relativistic blast wave with the density bumps that arise when the progenitor star rapidly loses a large fraction of its initial mass or when the ejected wind interacts with the external medium and decelerates. A re-brightening of the afterglow with a spectrum redder than the typical synchrotron spectrum (as seen in GRB 970508, GRB 980326 and GRB 000911) is predicted. We also calculate the luminosity of the reflected echo that arises when circumstellar material Compton-scatters the prompt radiation, and examine the spectral signatures expected from the interaction of the GRB afterglow with the ejected medium. [source] Applying the analytic theory of colliding ring galaxiesMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 3 2010Curtis Struck ABSTRACT An analytic theory of the waves in colliding ring galaxies was presented some years ago, but the observations were not of sufficient quality then to make quantitative comparisons. Well-resolved observations of a few systems are now available to make such comparisons, and structure imaged in several dozen systems, derived from the recent compilation of Madore, Nelson and Petrillo and the Galaxy Zoo project, can further constrain the theory. Systems with two rings are especially useful for deriving such constraints. After examining the implications of recent observations of ring sizes and structure, I extend the analytic theory, investigate limiting cases and present several levels of approximation. The theory is especially simple in the case of nearly flat rotation curves. I present observational comparisons for a few systems, including Arp 10, the Cartwheel and AM 2136,492. The fit is quite good over a large range of cases. For the Cartwheel there are discrepancies, but the areas of disagreement are suggestive of additional factors, such as multiple collisions. A specific prediction of the theory in the case of nearly flat rotation curves is that the ratio of the outward velocities of successive rings approximately equals the ratio of ring sizes. Ring velocities are also shown to scale simply with local circular velocities in this limit. [source] Toward a neuro-developmental account of the development of declarative memoryDEVELOPMENTAL PSYCHOBIOLOGY, Issue 1 2008Patricia J. Bauer Abstract The study of the biological bases of memory has a long history. Based on research with patients with specific lesions and disease, animal models, and neuroimaging studies, the neural substrate that supports declarative memory in adults has been relatively well articulated. By contrast, studies of the neural bases of memory in development is in its infancy. Yet joint consideration of the processes involved in building a memory trace, and of the time course of development of the neural structures involved, has contributed to the generation of specific predictions regarding the sources of age-related change. Specifically, there are suggestions that in infancy and very early childhood, encoding and consolidation processes account for substantial age-related variance in long-term declarative memory. With development, the locus of age-related variability in the vulnerability of memory traces shifts to the later-stage processes of memory storage and retrieval. These insights are afforded by consideration of multiple levels of analysis, from the biological to the behavioral. © 2007 Wiley Periodicals, Inc. Dev Psychobiol 50: 19,31, 2008. [source] The Silent Bared-Teeth Face and the Crest-Raise of the Mandrill (Mandrillus sphinx): a Contextual Analysis of Signal FunctionETHOLOGY, Issue 2 2005Mark E. Laidre The functions of two visual signals of the mandrill [silent bared-teeth face (SBTF) and crest-raise (CR)] were investigated by quantifying the probability of each signal occurring across a set of distinct contexts. The motivation for the investigation was twofold: (1) SBTF had been interpreted in diverse and sometimes contradictory ways, and (2) CR had been interpreted as a distinct signal from SBTF, despite indications that the two signals grade into one another. In our investigation we considered four functions for both SBTF and CR (threat, submissive, conciliatory, and ambivalent), and we made specific predictions about the relative probability that a signal with each of these functions should occur in different contexts. To determine if SBTF and CR represent a single graded signal, we analyzed them separately and together. We predicted that if they represent a single graded signal, then they should exhibit similar patterns of occurrence across contexts when they were analyzed separately, and that these patterns should be strengthened when they were analyzed together. The results showed that both SBTF and CR met the predictions for conciliatory signals, occurring most often in non-aggressive, non-hostile contexts and least often in aggressive, hostile contexts. The results were also consistent with the hypothesis that SBTF and CR represent a single graded signal. [source] LEAKY PREZYGOTIC ISOLATION AND POROUS GENOMES: RAPID INTROGRESSION OF MATERNALLY INHERITED DNAEVOLUTION, Issue 4 2005Kai M. A. Chan Abstract Accurate phylogenies are crucial for understanding evolutionary processes, especially species diversification. It is commonly assumed that "good" species are sufficiently isolated genetically that gene genealogies represent accurate phylogenies. However, it is increasingly clear that good species may continue to exchange genetic material through hybridization (introgression). Many studies of closely related species reveal introgression of some genes without others, often with more rapid introgression of maternally inherited chloroplast or mitochondrial DNA (cpDNA, mtDNA). We seek a general explanation for this biased introgression using simple models of common reproductive isolating barriers (RIBs). We compare empirically informed models of prezygotic isolation (for pre- and postinsemination mechanisms of both female choice and male competition) with postzygotic isolation and demonstrate that rate of introgression depends critically upon type of RIB and mode of genetic inheritance (maternal versus biparental versus paternal). Our frequency-dependent prezygotic RIBs allow much more rapid introgression of biparentally and maternally inherited genes than do commonly modeled postzygotic RIBs (especially maternally inherited DNA). After considering the specific predictions in the context of empirical observations, we conclude that our model of prezygotic RIBs is a general explanation for biased introgression of maternally inherited genomic components. These findings suggest that we should use extreme caution when interpreting single gene genealogies as species phylogenies, especially for cpDNA and mtDNA. [source] Ecological speciation in marine v. freshwater fishesJOURNAL OF FISH BIOLOGY, Issue 5 2009O. Puebla Absolute barriers to dispersal are not common in marine systems, and the prevalence of planktonic larvae in marine taxa provides potential for gene flow across large geographic distances. These observations raise the fundamental question in marine evolutionary biology as to whether geographic and oceanographic barriers alone can account for the high levels of species diversity observed in marine environments such as coral reefs, or whether marine speciation also operates in the presence of gene flow between diverging populations. In this respect, the ecological hypothesis of speciation, in which reproductive isolation results from divergent or disruptive natural selection, is of particular interest because it may operate in the presence of gene flow. Although important insights into the process of ecological speciation in aquatic environments have been provided by the study of freshwater fishes, comparatively little is known about the possibility of ecological speciation in marine teleosts. In this study, the evidence consistent with different aspects of the ecological hypothesis of speciation is evaluated in marine fishes. Molecular approaches have played a critical role in the development of speciation hypotheses in marine fishes, with a role of ecology suggested by the occurrence of sister clades separated by ecological factors, rapid cladogenesis or the persistence of genetically and ecologically differentiated species in the presence of gene flow. Yet, ecological speciation research in marine fishes is still largely at an exploratory stage. Cases where the major ingredients of ecological speciation, namely a source of natural divergent or disruptive selection, a mechanism of reproductive isolation and a link between the two have been explicitly documented are few. Even in these cases, specific predictions of the ecological hypothesis of speciation remain largely untested. Recent developments in the study of freshwater fishes illustrate the potential for molecular approaches to address specific questions related to the ecological hypothesis of speciation such as the nature of the genes underlying key ecological traits, the magnitude of their effect on phenotype and the mechanisms underlying their differential expression in different ecological contexts. The potential provided by molecular studies is fully realized when they are complemented with alternative (e.g. ecological, theoretical) approaches. [source] Differences in pollinator faunas may generate geographic differences in floral morphology and integration in Narcissus papyraceus (Amaryllidaceae)OIKOS, Issue 11 2007Rocío Pérez-Barrales Pollinators may generate selective pressures that affect covariation patterns of multiple traits as well as the mean values of single floral morphological traits. Berg predicted that flowers pollinated by animals whose morphology closely matches the flower's shape will be phenotypically more integrated (tighter correlation of flower traits) than will flowers pollinated by animals not closely fitting the floral morphology. We tested this hypothesis by comparing, in the Strait of Gibraltar region (south Spain, northern Morocco), populations of Narcissus papyraceus that have geographical differences in pollinator faunas. Long-tongued, nectar-feeding moths dominate the pollinator faunas of those populations close to the Strait of Gibraltar, whereas short-tongued, pollen-feeding syrphid flies dominate in peripheral populations farther from the Strait. Populations pollinated by moths and flies differed in the mean values of several floral traits, consistent with the evolution of regional pollination ecotypes. Populations pollinated by moths showed stronger intercorrelation (floral integration) than populations pollinated by hoverflies. Moth-pollinated populations also showed less variation in flower traits than vegetative traits, and this difference was stronger than in fly-pollinated populations. Thus, the pattern of differences in the phenotypic architecture of the Narcissus flowers is consistent with the hypothesis that populations have responded to different selective pressures generated by different pollinators. These data also supported most of the specific predictions of Berg's hypotheses about integration and modularity. [source] Host,pathogen protein interactions predicted by comparative modelingPROTEIN SCIENCE, Issue 12 2007Fred P. Davis Abstract Pathogens have evolved numerous strategies to infect their hosts, while hosts have evolved immune responses and other defenses to these foreign challenges. The vast majority of host,pathogen interactions involve protein,protein recognition, yet our current understanding of these interactions is limited. Here, we present and apply a computational whole-genome protocol that generates testable predictions of host,pathogen protein interactions. The protocol first scans the host and pathogen genomes for proteins with similarity to known protein complexes, then assesses these putative interactions, using structure if available, and, finally, filters the remaining interactions using biological context, such as the stage-specific expression of pathogen proteins and tissue expression of host proteins. The technique was applied to 10 pathogens, including species of Mycobacterium, apicomplexa, and kinetoplastida, responsible for "neglected" human diseases. The method was assessed by (1) comparison to a set of known host,pathogen interactions, (2) comparison to gene expression and essentiality data describing host and pathogen genes involved in infection, and (3) analysis of the functional properties of the human proteins predicted to interact with pathogen proteins, demonstrating an enrichment for functionally relevant host,pathogen interactions. We present several specific predictions that warrant experimental follow-up, including interactions from previously characterized mechanisms, such as cytoadhesion and protease inhibition, as well as suspected interactions in hypothesized networks, such as apoptotic pathways. Our computational method provides a means to mine whole-genome data and is complementary to experimental efforts in elucidating networks of host,pathogen protein interactions. [source] Effects of habitat fragmentation and disturbance on howler monkeys: a reviewAMERICAN JOURNAL OF PRIMATOLOGY, Issue 1 2010Víctor Arroyo-Rodríguez Abstract We examined the literature on the effects of habitat fragmentation and disturbance on howler monkeys (genus Alouatta) to (1) identify different threats that may affect howlers in fragmented landscapes; (2) review specific predictions developed in fragmentation theory and (3) identify the empirical evidence supporting these predictions. Although howlers are known for their ability to persist in both conserved and disturbed conditions, we found evidence that they are negatively affected by high levels of habitat loss, fragmentation and degradation. Patch size appears to be the main factor constraining populations in fragmented habitats, probably because patch size is positively related to food availability, and negatively related to anthropogenic pressures, physiological stress and parasite loads. Patch isolation is not a strong predictor of either patch occupancy or population size in howlers, a result that may be related to the ability of howlers to move among forest patches. Thus, we propose that it is probable that habitat loss has larger consistent negative effects on howler populations than habitat fragmentation per se. In general, food availability decreases with patch size, not only due to habitat loss, but also because the density of big trees, plant species richness and howlers' home range size are lower in smaller patches, where howlers' population densities are commonly higher. However, it is unclear which vegetation attributes have the biggest influence on howler populations. Similarly, our knowledge is still limited concerning the effects of postfragmentation threats (e.g. hunting and logging) on howlers living in forest patches, and how several endogenous threats (e.g. genetic diversity, physiological stress, and parasitism) affect the distribution, population structure and persistence of howlers. More long-term studies with comparable methods are necessary to quantify some of the patterns discussed in this review, and determine through meta-analyses whether there are significant inter-specific differences in species' responses to habitat loss and fragmentation. Am. J. Primatol. 72:1,16, 2010. © 2009 Wiley-Liss, Inc. [source] Phylogeography of spiny mice (genus Acomys, Rodentia: Muridae) from the south-western margin of the Sahara with taxonomic implicationsBIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY, Issue 1 2009VIOLAINE NICOLAS The present study aims to depict the overall pattern of Acomys history in south-western Sahara. We tested the specific predictions that: (1) several mitochondrial clades can be identified and that they coincide with the described species; (2) successive phases of desert expansion and contraction during the last 3 Myr have resulted in several phases of demographic expansion and population fragmentation in Acomys; and (3) isolation-by-distance occurs. The extent of phylogeographic patterns and molecular genetic diversity (cytochrome b gene and D-loop) were addressed in a survey of 90 individuals of Acomys from 38 localities. Our phylogeographical analyses show a strong genetic structure within western Saharan Acomys, with several phylogroups displaying non-overlapping geographic distributions. Restricted gene flow with isolation-by-distance was recorded and a signal of population expansion was detected within several clades. We suggest that during arid or semi-arid paleoclimatic periods, when large sandy areas were present, Acomys was restricted to rocky massifs, whereas, in more humid periods, when savannah and/or steppe habitat prevailed, this species was able to disperse and to survive outside rocky areas because food resources were abundant. Based on a comprehensive sampling and the use of an integrative approach (i.e. combining cytogenetic, molecular and morphological data), we firmly propose that Acomys airensis should be considered as a junior synonym of Acomys chudeaui. © 2009 The Linnean Society of London, Biological Journal of the Linnean Society, 2009, 98, 29,46. [source] |