Specific Consequences (specific + consequence)

Distribution by Scientific Domains


Selected Abstracts


Hydrodynamical N -body simulations of coupled dark energy cosmologies

MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 4 2010
Marco Baldi
ABSTRACT If the accelerated expansion of the Universe at the present epoch is driven by a dark energy scalar field, there may well be a non-trivial coupling between the dark energy and the cold dark matter (CDM) fluid. Such interactions give rise to new features in cosmological structure growth, like an additional long-range attractive force between CDM particles, or variations of the dark matter particle mass with time. We have implemented these effects in the N -body code gadget-2 and present results of a series of high-resolution N -body simulations where the dark energy component is directly interacting with the CDM. As a consequence of the new physics, CDM and baryon distributions evolve differently both in the linear and in the non-linear regime of structure formation. Already on large scales, a linear bias develops between these two components, which is further enhanced by the non-linear evolution. We also find, in contrast with previous work, that the density profiles of CDM haloes are less concentrated in coupled dark energy cosmologies compared with ,CDM, and that this feature does not depend on the initial conditions setup, but is a specific consequence of the extra physics induced by the coupling. Also, the baryon fraction in haloes in the coupled models is significantly reduced below the universal baryon fraction. These features alleviate tensions between observations and the ,CDM model on small scales. Our methodology is ideally suited to explore the predictions of coupled dark energy models in the fully non-linear regime, which can provide powerful constraints for the viable parameter space of such scenarios. [source]


How Much Do Rural Hispanics Know About the Adverse Health Risks of Smoking?

THE JOURNAL OF RURAL HEALTH, Issue 3 2001
Tania Butkovic B.S.
ABSTRACT: The object of this study was to measure knowledge in a rural Hispanic community about the adverse health effects of smoking and to compare knowledge between current smokers and nonsmokers. A survey was administered to waiting room patients (n=137) over 16 years old at three predominantly Hispanic rural community health centers in the central San Joaquin Valley of California. Proportions of respondents who believed that smoking caused a specific consequence were calculated and compared between smokers and nonsmokers by chi-square tests. Likelihood of attributing negative health consequences to smoking was determined and compared between smokers and nonsmokers. A majority of all participants (smokers and nonsmokers) knew that smoking causes lung cancer (93 percent) and emphysema (91 percent). Many fewer participants knew that smoking contributes to problems such as osteoporosis (39 percent) or sexual dysfunction (33 percent). Current smokers were less likely than nonsmokers (P=0.01) to say that smoking causes any adverse health outcome, including those not known to be related to smoking. Although this is a culturally, ethnically and geographically unique group, knowledge of smoking risks among smoking and nonsmoking rural Hispanics is similar to that found in the general population. When compared with nonsmokers, current smokers underestimate the risk that smoking poses to health. [source]


The role of the dorsomedial striatum in instrumental conditioning

EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 2 2005
Henry H. Yin
Abstract Considerable evidence suggests that, in instrumental conditioning, rats learn the relationship between actions and their specific consequences or outcomes. The present study examined the role of the dorsomedial striatum (DMS) in this type of learning after excitotoxic lesions and reversible, muscimol-induced inactivation. In three experiments, rats were first trained to press two levers for distinct outcomes, and then tested after training using a variety of behavioural assays that have been established to detect action-outcome learning. In Experiment 1, pre-training lesions of the posterior DMS abolished the sensitivity of rats' instrumental performance to both outcome devaluation and contingency degradation when tested in extinction, whereas lesions of the anterior DMS had no effect. In Experiment 2, both pre-training and post-training lesions of the posterior DMS were equally effective in reducing the sensitivity of performance both to devaluation and degradation treatments. In Experiment 3, the infusion of muscimol into the posterior DMS selectively abolished sensitivity of performance to devaluation and contingency degradation without impairing the ability of rats to discriminate either the instrumental actions performed or the identity of the earned outcomes. Taken together, these results suggest that the posterior region of the DMS is a crucial neural substrate for the acquisition and expression of action,outcome associations in instrumental conditioning. [source]


How Pervasive are Euro-Politics?

JCMS: JOURNAL OF COMMON MARKET STUDIES, Issue 2 2000
Effects of EU Membership on a New Member State
While the consequences of becoming an EU Member State for national policies are usually the core concern of pre-membership debates and of post-accession assessments, studies of the effects of European integration on the political systems of the Member States have so far been less numerous. Among the new EU members, which are ideal cases for studying domestic accession effects, Austria is a particularly challenging case in terms of top-down impact on the national political system. A number of specific precautions were taken in order to protect typical features of the national political system (notably the traditional roles of parliament, Länder and social partners) from being eroded in the multi-level system. The basic research question of this article is whether or not these measures were actually successful. How ,sticky' is the EU upon closer inspection, i.e. how pervasive are its effects on adverse national structures? Can national measures, even at the constitutional level, outweigh specific consequences of participating in Euro-politics? If not 9as the Austrian case indicates), why not? The conclusions distinguish specific Austrian variables from generalizable ones and discuss the findings in the light of the existing literature. [source]


Timing of Thyroid Hormone Action in the Developing Brain: Clinical Observations and Experimental Findings

JOURNAL OF NEUROENDOCRINOLOGY, Issue 10 2004
R. T. Zoeller
Abstract The original concept of the critical period of thyroid hormone (TH) action on brain development was proposed to identify the postnatal period during which TH supplement must be provided to a child with congenital hypothyroidism to prevent mental retardation. As neuropsychological tools have become more sensitive, it has become apparent that even mild TH insufficiency in humans can produce measurable deficits in very specific neuropsychological functions, and that the specific consequences of TH deficiency depends on the precise developmental timing of the deficiency. Models of maternal hypothyroidism, hypothyroxinaemia and congential hyperthyroidism have provided these insights. If the TH deficiency occurs early in pregnancy, the offspring display problems in visual attention, visual processing (i.e. acuity and strabismus) and gross motor skills. If it occurs later in pregnancy, children are at additional risk of subnormal visual (i.e. contrast sensitivity) and visuospatial skills, as well as slower response speeds and fine motor deficits. Finally, if TH insufficiency occurs after birth, language and memory skills are most predominantly affected. Although the experimental literature lags behind clinical studies in providing a mechanistic explanation for each of these observations, recent studies confirm that the specific action of TH on brain development depends upon developmental timing, and studies informing us about molecular mechanisms of TH action are generating hypotheses concerning possible mechanisms to account for these pleiotropic actions. [source]


Assessing the Severity of Hazardous Drinking and Related Consequences Among Incarcerated Women

ALCOHOLISM, Issue 5 2010
David R. Strong
Background:, Recent epidemiological efforts have demonstrated the utility of measuring individual differences in the severity of alcohol use along a single severity continuum marked by alcohol-related problems, symptoms of alcohol dependence, and the social consequences of drinking. Translation of this utility to specialized clinical populations is not assured. The expected inter-relationships among problems, symptoms and consequences, and enhanced sensitivity of combined assessments require confirmation in applied clinical settings. Method:, Subjects were 245 incarcerated women who met Alcohol Use Disorders Identification Test criteria for hazardous use of alcohol. Participants were recruited from a statewide adult correctional facility for an ongoing clinical trial testing the effectiveness of brief motivational interviewing on alcohol use and HIV risk behaviors. Participants ranged in age from 18 to 56 (M = 34.1, SD = 8.9), 71.4% were Caucasian, and 65.7% reported <12 years of education. Results:, Analyses suggested that the 6 problems of alcohol abuse, 7 symptoms for alcohol dependence, and 14 alcohol-related social consequences loaded to a single factor (0.38 to 0.85) that formed a continuum of alcohol severity. Contrary to epidemiological studies, physical fights and being arrested were the most prevalent consequences and were associated with lower alcohol severity in this population. Three of the five items that discriminated best between higher and lower alcohol severity were related to familial and relationship consequences. Conclusions:, Consistent with epidemiological studies, alcohol severity can be measured among incarcerated hazardously drinking women on a single continuum that includes alcohol problems, symptoms, and social consequences. Replication of the expected alignment of problems and symptoms supports the construct validity of the continuum and further challenges the proposed hierarchical structure of abuse/dependence distinction. Large differences in rates of specific consequences and observed effectiveness of tailored social consequence items suggest the benefits of cross-sample validation to improve evaluation of clinical outcomes. [source]