Home About us Contact | |||
Space Domain (space + domain)
Selected AbstractsUncoupling proteins 2 and 3 interact with members of the 14.3.3 familyFEBS JOURNAL, Issue 9 2000Benoit Pierrat Uncoupling proteins (UCPs) are members of the superfamily of the mitochondrial anion carrier proteins (MATP). Localized in the inner membrane of the organelle, they are postulated to be regulators of mitochondrial uncoupling. UCP2 and 3 may play an important role in the regulation of thermogenesis and, thus, on the resting metabolic rate in humans. To identify interacting proteins that may be involved in the regulation of the activity of UCPs, the yeast two-hybrid system was applied. Segments of hUCP2 containing the hydrophilic loops facing the intermembrane space, or combinations of these, were used to screen an adipocyte activation domain (AD) fusion library. The 14.3.3 protein isoforms ,, ,, , were identified as possible interacting partners of hUCP2. Screening of a human skeletal muscle AD fusion library, on the other hand, yielded several clones all of them encoding the , isoform of the 14.3.3 family. Mapping experiments further revealed that all these 14.3.3 proteins interact specifically with the C-terminal intermembrane space domain of both hUCP2 and hUCP3 whereas no interactions could be detected with the C-terminal part of hUCP1. Direct interaction between UCP3 and 14.3.3 , could be demonstrated after in vitro translation by coimmunoprecipitation. When coexpressed in a heterologous yeast system, 14.3.3 proteins potentiated the inhibitory effect of UCP3 overexpression on cell growth. These findings suggest that 14.3.3 proteins could be involved in the targeting of UCPs to the mitochondria. [source] Numerical determination of 3D temperature fields in steel jointsFIRE AND MATERIALS, Issue 2-4 2004Jean-Marc Franssen Abstract A numerical study was undertaken to investigate the temperature field in steel joints and to compare the temperatures in the joints with the temperatures of the adjacent steel members on the hypothesis that the thermal protection is the same on the joint and in the members. Very brief information is given on the numerical model, supplemented with parametric studies made in order to determine the required level of discretization in the time and in the space domain. A simplified assumption for representing the thermal insulation is also discussed and validated. Different numerical analyses are performed, with a variation of the following parameters: (i) type of joints, from very simple to more complex configurations, with welds and/or bolts, all of them representing joints between elements located in the same plane; (ii) unprotected joints or protected by one sprayed material; (iii) ISO, hydrocarbon or one natural fire scenario. The fact that the thermal attack from the fire might be less severe because the joints are usually located in the corner of the compartment is not taken into account. Copyright © 2004 John Wiley & Sons, Ltd. [source] Analytical solution for the electric potential in arbitrary anisotropic layered media applying the set of Hankel transforms of integer orderGEOPHYSICAL PROSPECTING, Issue 5 2006E. Pervago ABSTRACT The analytical solution and algorithm for simulating the electric potential in an arbitrarily anisotropic multilayered medium produced by a point DC source is here proposed. The solution is presented as a combination of Hankel transforms of integer order and Fourier transforms based on the analytical recurrent equations obtained for the potential spectrum. For the conversion of the potential spectrum into the space domain, we have applied the algorithm of the Fast Fourier Transform for logarithmically spaced points. A comparison of the modelling results with the power-series solution for two-layered anisotropic structures demonstrated the high accuracy and computing-time efficiency of the method proposed. The results of the apparent-resistivity calculation for both traditional pole-pole and tensor arrays above three-layered sequence with an azimuthally anisotropic second layer are presented. The numerical simulations show that both arrays have the same sensitivity to the anisotropy parameters. This sensitivity depends significantly on the resistivity ratio between anisotropic and adjacent layers and increases for the models with a conductive second layer. [source] Sloshing analysis of a liquid storage container using level set X-FEMINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Issue 4 2009Toshio Nagashima Abstract The extended finite element method (X-FEM), in conjunction with the level set method, is applied to sloshing analysis of a rigid container filled with liquid. The governing equations for liquid with a free surface based on the potential flow theory are discretized using the framework of level set X-FEM. Once the space domain of a container is modeled by tetrahedral elements, sloshing analysis for arbitrary liquid levels and configurations can be performed without remeshing. Natural frequencies of free surface sloshing motion in rigid containers of various shapes were computed by the proposed method and the results were compared with those obtained by theoretical solutions and experiments. The proposed method was demonstrated to perform sloshing analysis efficiently for rigid containers with various liquid levels and configurations. Copyright © 2008 John Wiley & Sons, Ltd. [source] Development of a New Comprehensive Ocean Atlas for Indian Ocean utilizing ARGO DataINTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 2 2010B. Prasad Kumar Abstract The World Ocean Atlas (WOA), also termed ,Levitus Climatology', is a global ocean climatology containing monthly, seasonal and annual means of temperature (T) and salinity (S) fields at standard ocean depths. The monthly climatology for T and S is available for standard depths up to 1000 m. The database used in the preparation of this climatology (WOA) are historical records of Conductivity, Temperature and Depth (CTD) casts and other available marine observations collected in the past. The methodology used in preparation of this WOA is objective analysis which is essentially non-synoptic and widely scattered in the space domain. We understand that ARGO data has so far not been blended with WOA, nor has its impact for improving WOA climatology been attempted. Presently, with the wealth of marine data from ARGO profilers in the Indian Ocean, we propose a new approach to reconstruct T and S fields optimally utilizing the ARGO data. Here we develop a new model using Delaunay Tessellation with QHull algorithm delivering three-dimensional T and S fields from a non-uniform scattered database up to a depth of 1000 m. For gaps in a data-sparse region, we use all available quality-checked Ocean Station Data (OSD) and Profiling Float Data (PFL) information on T and S, in addition to the existing ARGO data. The initiative here was to replace WOA data points with realistic information from ARGO and in situ data, thereby producing a new climatology atlas. We demonstrate the robustness of our approach, and the final climatology on T and S is better compared with the existing state-of-the-art WOA. The advantage of the proposed methodology is the scope of improving the ocean atlas with the addition of more ARGO data in the near future. The clustered approach in modelling enables ocean parameter retrieval in geometrically disconnected regions with an option for hot restart. We believe that the new climatology will benefit the research community immensely. Copyright © 2009 Royal Meteorological Society [source] Asymptotic behaviour for a two-dimensional thermoelastic modelMATHEMATICAL METHODS IN THE APPLIED SCIENCES, Issue 5 2007M. Fabrizio Abstract In this paper we study a thermoelastic material with an internal structure which binds the materials fibres to a quadratic behaviour. Moreover, a hereditary constitutive law for heat flux is supposed. We prove results of asymptotic stability and exponential decay for the evolution problem in two-dimensional space domain. Copyright © 2006 John Wiley & Sons, Ltd. [source] Analytical modelling of the current distribution in resistive loaded thin-wire antennas excited by a transient electric fieldMICROWAVE AND OPTICAL TECHNOLOGY LETTERS, Issue 4 20062Article first published online: 28 FEB 200, F. Sagnard Abstract The analytical modelling of the excitation of a Wu and King loaded dipole by an oblique transient electric-plane wavefront has been revisited and extended in order to analyze in detail the physical phenomena involved in the time and space domains. The role of several components of the current induced along a dipole as a function of different parameters is discussed. The modelling developed herein allows us to consider a V-dipole. This study will allow us to consider, in a future work, the case of an assembly of dipoles in the space domain for representing more complex antenna geometries. © 2006 Wiley Periodicals, Inc. Microwave Opt Technol Lett 48: 730,736, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.21459 [source] Applications of transformed-space non-uniform PSTD (TSNU-PSTD) in scattering analysis without the use of the non-uniform FFTMICROWAVE AND OPTICAL TECHNOLOGY LETTERS, Issue 1 2003Xiaoping Liu Abstract In this work, we extend the transformed-space, non-uniform pseudo-spectral time domain (TSNU-PSTD) Maxwell solver for a 2D scattering analysis. Prior to implementing the PSTD in this analysis, we first transform the non-uniform grids {xi} and {yj} sampled in the real space for describing complex geometries to uniform ones {ui} and {vj}, in order to fit the dimensions of practical structures and utilize the standard fast Fourier transform (FFT). Next, we use a uniform-sampled, standard FFT to represent spatial derivatives in the space domain of (u, v). It is found that this scheme is as efficient as the conventional uniform PSTD with the computational complexity of O(N log N), since the difference is only the factors of du/dx and dv/dy between the conventional PSTD and the TSNU-PSTD technique. Additionally, we apply an anisotropic version of the Berenger's perfectly matched layers (APML) to suppress the wraparound effect at the open boundaries of the computational domain, which is caused by the periodicity of the FFT. We also employ the pure scattered-field formulation and develop a near-to-far-zone field transformation in order to calculate scattered far fields. © 2003 Wiley Periodicals, Inc. Microwave Opt Technol Lett 38: 16,21, 2003 [source] Solving a fourth-order fractional diffusion-wave equation in a bounded domain by decomposition methodNUMERICAL METHODS FOR PARTIAL DIFFERENTIAL EQUATIONS, Issue 4 2008Hossein Jafari Abstract In this article, the Adomian decomposition method has been used to obtain solutions of fourth-order fractional diffusion-wave equation defined in a bounded space domain. The fractional derivative is described in the Caputo sense. Convergence of the method has been discussed with some illustrative examples. © 2007 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2008 [source] Determination of grave locations in Dedemezari Necropolis (Western Turkey) using magnetic field derivativesARCHAEOLOGICAL PROSPECTION, Issue 4 2008A. Büyüksaraç Abstract The location of the study area for this research of a Middle Bronze Age Necropolis is situated in the west of Turkey near Afyonkarahisar. Magnetic surveying was carried out in two adjacent areas (Areas 4 and 5). Four trenches have been excavated so far and graves were located in positions interpreted from a magnetic survey carried out in 2005. Initial excavations have shown that cist, pithos and simple graves were placed randomly and it is suggested that Dedemezari Necropolis is similar to the well known necropoleis of Gordion and Sariket. This paper compares the results of some phase-based filters which show improved performance as edge detectors in different ways. The filters are demonstrated on synthetic magnetic data and magnetic field data from Dedemezari Necropolis. Magnetic field derivatives, both vertical and horizontal, are common and useful tools for interpretation of the magnetic anomalies. Interpretation of magnetic field derivatives, separately or together, provide images of shallow bodies from magnetic data. The horizontal derivatives of the total magnetic field were computed in the space domain by means of finite-difference relationships, and the vertical derivative was computed in the frequency domain by using fast Fourier transform filtering. Derivatives of the magnetic anomalies have been used for detection of causative bodies. The analytic signal (AS), the enhanced horizontal derivative (EHD), tilt derivative (TD), theta map, hyperbolic tilt angle (HTA) and total horizontal derivative (THDR) methods were applied not only to synthetic anomalies but also to the measured magnetic anomalies of Areas 4 and 5. However, AS and EHD produced the best results as the other methods created edge effects. Copyright © 2008 John Wiley & Sons, Ltd. [source] Analytical modelling of the current distribution in resistive loaded thin-wire antennas excited by a transient electric fieldMICROWAVE AND OPTICAL TECHNOLOGY LETTERS, Issue 4 20062Article first published online: 28 FEB 200, F. Sagnard Abstract The analytical modelling of the excitation of a Wu and King loaded dipole by an oblique transient electric-plane wavefront has been revisited and extended in order to analyze in detail the physical phenomena involved in the time and space domains. The role of several components of the current induced along a dipole as a function of different parameters is discussed. The modelling developed herein allows us to consider a V-dipole. This study will allow us to consider, in a future work, the case of an assembly of dipoles in the space domain for representing more complex antenna geometries. © 2006 Wiley Periodicals, Inc. Microwave Opt Technol Lett 48: 730,736, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.21459 [source] |