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Splenic Volume (splenic + volume)
Selected AbstractsEffects of altitude on spleen volume: Sonographic assessmentJOURNAL OF CLINICAL ULTRASOUND, Issue 4 2007Guner Sonmez MD Abstract Purpose. To use sonography to determine changes that may arise in splenic volume in humans from regions of lower altitude who begin to live in regions of higher altitude. Materials and Methods. The study was conducted in the Turkish province of A,r,, at an altitude of 1750 m and included 108 healthy, nonsmoking, disease-free volunteers who had moved from regions at an altitude lower than 500 m. Length, width, and thickness of the spleen were measured using sonography. Splenic volume was calculated using the following standard ellipsoid formula: length × width × thickness × 0.523. Sonographic assessments were repeated at 3 and 6 months along with other blood tests, including hemoglobin, hematocrit, and platelet levels. Results. The mean ± SD splenic volume was 299 ± 97 cm3 (range, 116,574 cm3). At 3 and 6 months, the splenic volumes decreased significantly compared to their initial values (p < 0.05). An increase in hemoglobin, hematocrit, and platelet count was observed in all subjects. Conclusion. Our data show that splenic volume in healthy individuals who begins to live at high altitudes decreases gradually. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2007 [source] Predictive factors for platelet increase after partial splenic embolization in liver cirrhosis patientsJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Issue 10 2007Hiromitsu Hayashi Abstract Background and Aim:, Partial splenic embolization (PSE) is often performed for improving thrombocytopenia in cirrhotic patients. We investigated the largely unclear predictive factors for platelet increase at both 1 month and 1 year after PSE. Methods:, Aimed at increasing the platelet count, PSE was performed in 42 cirrhotic patients with thrombocytopenia (platelets < 80 × 104/mL) caused by hypersplenism. The clinical data were analyzed to clarify the predictive factors for platelet increase at 1 month (n = 42) and 1 year (n = 38) after PSE. Results:, The mean splenic infarction ratio was 76.7% ± 11.2%. The platelet count increased to 259% ± 112% and 228% ± 75% of the pretreatment values at 1 month and at 1 year after PSE, respectively. Stepwise multiple linear regression analysis showed that the infarcted splenic volume had a positive independent association with the increase in platelet count at both 1 month (P = 0.00004) and 1 year (P = 0.005) after PSE (increase in platelet count (×104/mL): at 1 month = 0.752 + 0.018 × infarcted splenic volume (mL), R2 = 0.344; at 1 year = 2.19 + 0.01 × infarcted splenic volume (mL), R2 = 0.203). Receiver operating characteristic analysis yielded a cut-off value of 388 mL of infarcted splenic volume for achieving an increase of 5.0,8.0 × 104/mL in platelet count at 1 year. Conclusions:, PSE can reduce the platelet pool and induce an increase in platelet count. This increase is greatly dependent on the infarcted splenic volume. [source] Three-dimensional sonographic volume measurement of the fetal spleenJOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (ELECTRONIC), Issue 5 2007Toshiyuki Hata Abstract Aim:, The objective of this longitudinal study was to evaluate the growth of the fetal spleen in normal pregnancies, using three-dimensional ultrasound. Methods:, Three-dimensional sonographic examinations were performed on 14 appropriate-for-gestational-age fetuses. Fetal splenic volume was measured every 2,3 weeks after 20 weeks of gestational age until delivery. Results:, Curvilinear relationships were found between the gestational age and splenic volume (R2 = 80.2%, P < 0.0001), and normal ranges of splenic volume measurements for estimating the growth of the fetal spleen during normal pregnancy were generated. We found that the splenic volume calculation based on the equation for the volume of the ellipsoid by conventional two-dimensional ultrasound in previous investigations is about twice as large as that using three-dimensional ultrasound in our study, whereas the present data described in this study is quite comparable with previous data from an autopsy series. Conclusion:, Our findings suggest that the standard curve for the fetal splenic volume using three-dimensional ultrasound provides a superior means for evaluating the normal splenic growth in the fetus and for identifying splenic abnormalities in utero. However, the data and its interpretation in our study should be taken with some degree of caution because of the small number of subjects studied. Further studies involving a larger sample size would be needed to confirm these findings. [source] Remnant liver regeneration and spleen volume changes after living liver donation: influence of the middle hepatic veinCLINICAL TRANSPLANTATION, Issue 6 2006Tai-Yi Chen Abstract:, Background and objectives:, Graft harvest with or without the middle hepatic vein (MHV) affects venous return and function of the remaining liver. The aims of this study are to compare the remnant liver volume and spleen changes in the donors of different types of graft harvest and to evaluate the influence of resection with or without the MHV on the remnant liver volume regeneration, spleen volume change and serum total bilirubin. Patients and methods: A total of 165 donors were grouped according to the type of graft harvest: 88 donors underwent left lateral segmentectomy (LLS), 10 donors underwent extend LLS or left lobectomy (LL), and 67 donors underwent right lobectomy (RL). Groups LLS and LL were later combined as group LH (left hepatectomy, n = 98). There were 68 men and 97 women. The mean age was 32.9 ± 8.1 yr. The total liver volume (LV) and spleen volume (S1) before graft harvest, graft weight (GW), regenerated liver volume (LV6m) and spleen volume (S2) six months post-donation were calculated. Results:, There were no significant differences in the regenerated liver volume six months postoperation (LV6m) and recovery ratio (LV6m/LV × 100%) among the different groups, albeit significant smaller LV6m in both groups compared with the initial liver volume was noted. Postoperative spleen volume (S2), average spleen ratio (S2/S1) and spleen change ratio were significantly larger and higher in group RL than in group LH. A significant increase in spleen volume was noted in both groups six months after graft harvest. A significantly higher TB in group RL (4.1 ± 1.7 mg/dL, range: 1.4,8.5 mg/dL) was noted compared with that of group LH (1.6 ± 1.0 mg/dL, range: 0.7,6.2 mg/dL). Conclusion: There was a significant increase in the regenerated remnant liver and splenic volumes six months postoperation in all types of hepatectomy following living donor hepatectomy, and there was no difference in the mean TB levels among donors whether the MHV was included or not in the graft. [source] | ||||||||||