Software Technology (software + technology)

Distribution by Scientific Domains


Selected Abstracts


Novel software architecture for rapid development of magnetic resonance applications

CONCEPTS IN MAGNETIC RESONANCE, Issue 3 2002
Josef Debbins
Abstract As the pace of clinical magnetic resonance (MR) procedures grows, the need for an MR scanner software platform on which developers can rapidly prototype, validate, and produce product applications becomes paramount. A software architecture has been developed for a commercial MR scanner that employs state of the art software technologies including Java, C++, DICOM, XML, and so forth. This system permits graphical (drag and drop) assembly of applications built on simple processing building blocks, including pulse sequences, a user interface, reconstruction and postprocessing, and database control. The application developer (researcher or commercial) can assemble these building blocks to create custom applications. The developer can also write source code directly to create new building blocks and add these to the collection of components, which can be distributed worldwide over the internet. The application software and its components are developed in Java, which assures platform portability across any host computer that supports a Java Virtual Machine. The downloaded executable portion of the application is executed in compiled C++ code, which assures mission-critical real-time execution during fast MR acquisition and data processing on dedicated embedded hardware that supports C or C++. This combination permits flexible and rapid MR application development across virtually any combination of computer configurations and operating systems, and yet it allows for very high performance execution on actual scanner hardware. Applications, including prescan, are inherently real-time enabled and can be aggregated and customized to form "superapplications," wherein one or more applications work with another to accomplish the clinical objective with a very high transition speed between applications. © 2002 Wiley Periodicals, Inc. Concepts in Magnetic Resonance (Magn Reson Engineering) 15: 216,237, 2002 [source]


Evaluation of cytogenetic effects of lambda-cyhalothrin on human lymphocytes

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, Issue 5 2005
Rambabu Naravaneni
Abstract The genotoxic and cytotoxic potential of lambda-cyhalothrin (LCT), a synthetic pyrethroid insecticide, was investigated on human lymphocytes cultured in vitro. Utilizing the trypan blue dye exclusion technique assay, the LC50 of LCT was found to be 28 , M. Based on the LC50 value, it is seen that LCT was highly toxic to lymphocyte cultures, among other pyrethroid group of pesticides. Chromosomal aberrations induced by LCT were determined using metaphase plate-spreads of lymphocytes. The chromosomal analysis was recorded using Medi-Image software technology. The analysis revealed that more satellite associations and gaps were found, which were statistically significant (p < 0.05) when compared to controls. Comet assay was used to assess the possibility of LCT to induce the damage in DNA, where the increase in comet tail length relates to the extent of DNA single strand breaks. The results presented here indicate that in vitro assays could be used as indicators of cytotoxicity and genotoxicity of the pesticide. © 2005 Wiley Periodicals, Inc. J Biochem Mol Toxicol 19:304,310, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20095 [source]


Effect of smoking on the gingival capillary density: assessment of gingival capillary density with orthogonal polarization spectral imaging

JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 12 2005
J. A. Lindeboom
Abstract Objectives: Microvascular changes because of smoking are frequently presumed in models because of the negative effect of smoking portrayed on the microcirculation. We hypothesized that cigarette smoke might lead to a decrease in gingival capillary density. Materials and Methods: Capillary density was assessed with orthogonal polarization spectral (OPS) imaging, a technique using special optics by which a virtual light source is created at a depth of 1 mm within the mucosa. The light is absorbed by haemoglobin, resulting in an image of the capillaries in negative contrast. The gingival capillary density was measured in 20 healthy male dental students with a mean age of 25. Ten of the students were smokers and 10 were non-smokers. In each subject six images of the right maxillary pre-molar region were obtained, and the mean gingival capillary density was determined through the use of K&K software technology. Results: The mean capillary density in smokers was 69.3±8.9 capillaries per visual field compared with a mean capillary density in non-smokers of 60.6±5.4 (p=0.33). Conclusion: No significant differences were found between the gingival capillary density of smokers and non-smokers. [source]


Community-based individual knowledge construction in the classroom: a process-oriented account

JOURNAL OF COMPUTER ASSISTED LEARNING, Issue 3 2010
C.-K. Looi
Abstract This paper explores the process of knowledge convergence and knowledge sharing in the context of classroom collaboration in which students do a group learning activity mediated by a generic representation tool. In analysing the transcript of the interactions of a group, we adapt the group cognition method of Stahl and the uptake analysis methodology of Suthers to understand how the members of the group did meaning making in their interactions, and how individual members did uptakes of their interactions and applied their new shared knowledge or understanding in new situations. The transcript is taken from our school-based research using the Group Scribbles software technology which provides representation spaces for individual, group or class work to support collaborative practices. Our work contributes toward a methodology for explaining a process-oriented account of a small group interaction through face-to-face communication over external shared representations. [source]