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Single Component (single + component)
Selected AbstractsLocal Velocity and Concentration of the Single Components in Water/Oil Mixtures Monitored by Means of MRI Flow Experiments in Steady Tube FlowCHEMICAL ENGINEERING & TECHNOLOGY (CET), Issue 1 2003J. Götz Abstract In this paper the spatially resolved determination of velocities in two-phase systems consisting of water and oil by means of nuclear magnetic resonance (NMR) imaging (MRI) techniques is described and applied to steady tube flows with regard to the total flow rate. As MRI offers the possibility to study the flow of multiphase materials spatially resolved with various forms of contrast, even optically opaque water/oil mixtures can be studied in the interior of the material. Besides snapshot images of the actual flow pattern also local velocity and concentration fields of both phases can be obtained separately. The insight into the inner micro flow processes and microstructure allows to characterize fluid mixtures or emulsions. Flow rate and preparation/mixing method were varied in order to realize changes of the flow pattern and the structure of the mixture during flow. Physical models of the flow behavior and physical stability of these complex systems can be based upon this information. [source] Usability levels for sparse linear algebra components,CONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 12 2008M. Sosonkina Abstract Sparse matrix computations are ubiquitous in high-performance computing applications and often are their most computationally intensive part. In particular, efficient solution of large-scale linear systems may drastically improve the overall application performance. Thus, the choice and implementation of the linear system solver are of paramount importance. It is difficult, however, to navigate through a multitude of available solver packages and to tune their performance to the problem at hand, mainly because of the plethora of interfaces, each requiring application adaptations to match the specifics of solver packages. For example, different ways of setting parameters and a variety of sparse matrix formats hinder smooth interactions of sparse matrix computations with user applications. In this paper, interfaces designed for components that encapsulate sparse matrix computations are discussed in the light of their matching with application usability requirements. Consequently, we distinguish three levels of interfaces, high, medium, and low, corresponding to the degree of user involvement in the linear system solution process and in sparse matrix manipulations. We demonstrate when each interface design choice is applicable and how it may be used to further users' scientific goals. Component computational overheads caused by various design choices are also examined, ranging from low level, for matrix manipulation components, to high level, in which a single component contains the entire linear system solver. Published in 2007 by John Wiley & Sons, Ltd. [source] Detecting functional nodes in large-scale cortical networks with functional magnetic resonance imaging: A principal component analysis of the human visual systemHUMAN BRAIN MAPPING, Issue 9 2007Christine Ecker Abstract This study aimed to demonstrate how a regional variant of principal component analysis (PCA) can be used to delineate the known functional subdivisions of the human visual system. Unlike conventional eigenimage analysis, PCA was carried out as a second-level analysis subsequent to model-based General Linear Model (GLM)-type functional activation mapping. Functional homogeneity of the functional magnetic resonance imaging (fMRI) time series within and between clusters was examined on several levels of the visual network, starting from the level of individual clusters up to the network level comprising two or more distinct visual regions. On each level, the number of significant components was identified and compared with the number of clusters in the data set. Eigenimages were used to examine the regional distribution of the extracted components. It was shown that voxels within individual clusters and voxels located in bilateral homologue visual regions can be represented by a single component, constituting the characteristic functional specialization of the cluster(s). If, however, PCA was applied to time series of voxels located in functionally distinct visual regions, more than one component was observed with each component being dominated by voxels in one of the investigated regions. The model of functional connections derived by PCA was in accordance with the well-known functional anatomy and anatomical connectivity of the visual system. PCA in combination with conventional activation mapping might therefore be used to identify the number of functionally distinct nodes in an fMRI data set in order to generate a model of functional connectivity within a neuroanatomical network. Hum Brain Mapp, 2006. © 2006 Wiley-Liss, Inc. [source] An efficient multivariate approach for estimating preference when individual observations are dependentJOURNAL OF ANIMAL ECOLOGY, Issue 5 2008Steinar Engen Summary 1We discuss aspects of resource selection based on observing a given vector of resource variables for different individuals at discrete time steps. A new technique for estimating preference of habitat characteristics, applicable when there are multiple individual observations, is proposed. 2We first show how to estimate preference on the population and individual level when only a single site- or resource component is observed. A variance component model based on normal scores in used to estimate mean preference for the population as well as the heterogeneity among individuals defined by the intra-class correlation. 3Next, a general technique is proposed for time series of observations of a vector with several components, correcting for the effect of correlations between these. The preference of each single component is analyzed under the assumption of arbitrarily complex selection of the other components. This approach is based on the theory for conditional distributions in the multi-normal model. 4The method is demonstrated using a data set of radio-tagged dispersing juvenile goshawks and their site characteristics, and can be used as a general tool in resource or habitat selection analysis. [source] The removal of iron and cobalt from aqueous solutions by ion exchange with Na-Y zeolite: batch, semi-batch and continuous operationJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 6 2002Jong Sung Kim Abstract The removal of single component and binary mixtures of divalent cobalt and iron from water by ion exchange with synthetic Y zeolite has been studied in batch, semi-batch and continuous modes of operation; the initial metal solution concentration did not exceed 2,mmol,dm,3. Binary Co/Na and Fe/Na ion exchange equilibrium isotherms (294,K) are presented wherein exchange site heterogeneity is evident in the case of the iron treatment. Under conditions of stoichiometric ion exchange, removal efficiencies for both cobalt and iron decrease with increasing metal concentration (0.2,2,mmol,dm,3) and the values were similar for both metals. Removal of cobalt under transient conditions was found to be temperature dependent. In the fixed bed operation, break-through behavior was sensitive to changes in both flow rate and inlet concentration. The break-through profiles for both metals under competitive and non-competitive conditions are presented; iron removal is lower in the presence of cobalt and vice versa. An in situ regeneration of the fully loaded zeolite by back exchange with sodium is considered and the exchange capacity of the regenerated zeolite is reported. The feasibility of employing cycles of heavy metal uptake/zeolite regeneration is addressed. © 2002 Society of Chemical Industry [source] Effect of molecular weight, temperature, and additives on the moisture sorption properties of polyethylene glycolJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 1 2010Jared A. Baird Abstract Polyethylene glycol (PEG) is a hygroscopic polymer that undergoes the phenomenon of deliquescence once a critical relative humidity (RH0) is reached. The purpose of this study was to test the hypothesis that the deliquescence behavior of PEG will be affected by the polymer molecular weight, temperature, and the presence of additives. The deliquescence relative humidity for single component (RH0) and binary mixtures (RH0,mix) were measured using an automated gravimetric moisture analyzer at 25 and 40°C. Changes in PEG crystallinity after exposure to moisture were qualitatively assessed using powder X-ray diffraction (PXRD). Optical microscopy was used to visually observe the deliquescence phenomenon. For single component systems, decreasing PEG MW and elevating the temperature resulted in a decrease in the observed RH0. Physical mixtures of acetaminophen and anhydrous citric acid with both PEG 3350 and PEG 100,000 exhibited deliquescence (RH0,mix) at a relative humidity below that of either individual component. Qualitative changes in crystallinity were observed from the X-ray diffractograms for each PEG MW grade at high relative humidities, indicating that phase transformation (deliquescence) of the samples had occurred. In conclusion, it was found that the deliquescence behavior of PEG was affected by the polymer MW, temperature, and the presence of additives. This phenomenon may have important implications for the stability of PEG containing formulations. © 2009 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 99:154,168, 2010 [source] Search-based many-to-one component substitutionJOURNAL OF SOFTWARE MAINTENANCE AND EVOLUTION: RESEARCH AND PRACTICE, Issue 5 2008Nicolas Desnos Abstract In this paper, we present a search-based automatic many-to-one component substitution mechanism. When a component is removed from an assembly to overcome component obsolescence, failure or unavailability, most existing systems perform component-to-component (one-to-one) substitution. Thus, they only handle situations where a specific candidate component is available. As this is not the most frequent case, it would be more flexible to allow a single component to be replaced by a whole component assembly (many-to-one component substitution). We propose such an automatic substitution mechanism, which does not require the possible changes to be anticipated and which preserves the quality of the assembly. This mechanism requires components to be enhanced with ports, which provide synthetic information on components' assembling capabilities. Such port-enhanced components then constitute input data for a search-based mechanism that looks for possible assemblies using various heuristics to tame complexity. Copyright © 2008 John Wiley & Sons, Ltd. [source] Experiments for derived factors with application to hydraulic gear pumpsJOURNAL OF THE ROYAL STATISTICAL SOCIETY: SERIES C (APPLIED STATISTICS), Issue 2 2001C. J. Sexton For experiments on mechanical products composed of several components, such as a hydraulic gear pump, conventional methods of designing and implementing factorial experiments can be impractical because of the prohibitive costs of obtaining certain components with factors set to prespecified values. A further difficulty is that often some of the factors that are believed to influence the product's performance are not features of a single component but are derived as functions of the dimensions of several components arising from the product's assembly. Experiments are proposed which use a sample of measured components to explore the influence of such derived factors. An algorithmic method for obtaining efficient designs is presented and applied to finding plans for studies on the gear pump. An experiment on the pump is described which involved both conventional and derived factors. This experiment led to new knowledge on how to improve the engineering design of the pump and, in particular, on how to improve its robustness to the varying pressures that are experienced in operation. [source] Intracluster light and the extended stellar envelopes of cD galaxies: an analytical descriptionMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 4 2007Marc S. Seigar ABSTRACT We have analysed deep R -band images, down to a limiting surface brightness of 26.5 R-mag arcsec,2 (equivalent to ,28 B-mag arcsec,2), of five cD galaxies to determine the shape of the surface brightness profiles of their extended stellar envelopes. Both de Vaucouleurs R1/4 and Sérsic R1/n models, on their own, provide a poor description of the surface brightness profiles of cD galaxies. This is due to the presence of outer stellar envelopes, thought to have accumulated over the merger history of the central cluster galaxy and also from the tidal stripping of galaxies at larger cluster radii. We therefore simultaneously fit two Sérsic functions to measure the shape of the inner and outer components of the cD galaxies. We show that, for three out of our five galaxies, the surface brightness profiles are best fitted by an inner Sérsic model, with indices n, 1 ,6, and an outer exponential component. For these systems, the galaxy-to-envelope size ratio is 0.1,0.4 and the contribution of the stellar envelope to the total R -band light (i.e. galaxy + envelope) is around 60,80 per cent (based on extrapolation to a 300 kpc radius). The exceptions are NGC 6173, for which our surface brightness profile modelling is consistent with just a single component (i.e. no envelope) and NGC 4874 which appears to have an envelope with a de Vaucouleurs, rather than exponential, profile. [source] Designed Fabrication of Silica-Based Nanostructured Particle Systems for Nanomedicine Applications,ADVANCED FUNCTIONAL MATERIALS, Issue 23 2008Yuanzhe Piao Abstract Suitably integrating multiple nanomaterials into nanostructured particle systems with specific combinations of properties has recently attracted significant attention in the research community. In particular, numerous particle systems have been designed and fabricated by integrating diverse materials with monodispersed silica nanoparticles. One or more distinct nanomaterials can be assembled on, encapsulated within, or integrated both inside and on the surface of silica nanoparticles using different chemistries and techniques to create multifunctional nanosystems. Research on these particle systems for biomedical applications has progressed rapidly during recent years due to the synergistic advantages of these complexes compared to the use of single components. This feature article surveys recent research progress on the fabrication strategies of these nanoparticle systems and their applications to medical diagnostics and therapy, thereby paving the way for the emerging field of nanomedicine. [source] Organizational emergence in networked collaborationINTERNATIONAL JOURNAL OF COMMUNICATION SYSTEMS, Issue 7 2002Ari-Pekka Hameri Abstract Research on complex adaptive systems has generated several conceptual parables to explain systems with emergent behaviour. One prominent use for terms such as self-organization, evolutionary trajectories, co-evolution and punctuated equilibrium has been in understanding human organizations. In such systems, emergent behaviour is demonstrated in novel structures, processes and spin-offs that cannot be explained just by studying single components of the organization and the intelligence embedded in them. Instead of solely exploiting the qualitative explanatory power of the evolutionary concepts, this paper focuses also on quantitative methods to track emergent behaviour in a globally distributed, constantly fluctuating and highly networked project organization. The underlying case is that of CERN (CERN, the European Laboratory for Particle Physics, has its headquarters in Geneva. At present, its Member States are Austria, Belgium, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Italy, Netherlands, Norway, Poland, Portugal, the Slovak Republic, Spain, Sweden, Switzerland and the United Kingdom. Israel, the Russian Federation, Turkey, Yugoslavia (status suspended after the UN embargo, June 1992), the European Commission and UNESCO have observer status.) and its decade long accelerator project, which strongly relies on electronic communication and networking to achieve its major objectives due to be accomplished by the year 2006. By using time series and self-organizing maps to analyse the global interaction among project groups and individuals the paper provides new insight to the understanding of emergent behaviour in human organizations. The key result of the study concerns the rigid deep structure of each case organization that seems to remain intact for the duration of the whole project. Copyright © 2002 John Wiley & Sons, Ltd. [source] Inflammatory bowel disease pathogenesis: therapeutic implicationsJOURNAL OF DIGESTIVE DISEASES, Issue 1 2005Claudio FIOCCHI The pathogenesis of inflammatory bowel disease (IBD) is complex, involving environmental, genetic, microbial, and immune factors. Therefore, treatment should target components that either predispose to or mediate the chronic inflammatory response of IBD. At the moment it is assumed that all components are necessary to have the typical manifestations of IBD but, in reality, it is unclear to what extent each factor contributes to the disease process, and whether some are more important than others. In addition, some factors are not practical targets; for example, environmental factors are poorly defined, too numerous, and require changes that cannot be implemented by the physician or the patient alone. The same is true for genetic factors that are still not amenable to therapeutic manipulations for technical and ethical reasons. This leaves microbial and immune factors as the two categories that can be selected for therapeutic intervention and where all current treatments are focused. The commensal gut flora can be qualitatively or quantitatively modified with antibiotics, probiotics, or diet, and a better characterization of enteric bacteria strains should help greatly in developing more effective therapies. Most current drugs are focused on inhibiting pro-inflammatory molecules produced by immune cells, including biological agents that block specific cytokines such as tumor necrosis factor-alpha. It is anticipated that combination therapies targeting multiple pathogenic components will prove more effective than those blocking single components of IBD pathogenesis. [source] THE FOULING AND CLEANING OF ULTRAFILTRATION MEMBRANES DURING THE FILTRATION OF MODEL TEA COMPONENT SOLUTIONSJOURNAL OF FOOD PROCESS ENGINEERING, Issue 3 2007DAN WU ABSTRACT Proteins and polyphenols are the principal fouling constituents in the ultrafiltration (UF) of black tea liquor. The aim of this study was to determine the relative importance of individual components in the fouling process, to investigate any synergetic interactions that were occurring and to compare the cleaning characteristics of different fouled membranes. A 30-kD molecular weight cutoff polysulfone UF membrane in dead-end mode was challenged with model solutions of tea components. Model solutions consisted of tea proteins, theaflavins (TFs), thearubigins and caffeine. Sodium hydroxide was used as a cleaning reagent. Permeate flux decline curves were presented for single components and mixtures. Individual component transfer fluxes and rejections were also presented. An unexpected finding was that protein in a mixture with TFs could permeate the membrane to a degree, while a protein solution in the absence of the polyphenol was completely rejected. The inspection of membranes fouled by different solutions revealed different foulant morphologies. Membrane cleaning with 0.2 wt % sodium hydroxide was generally found to be effective. [source] Towards a specific characterisation of components on a cell surface,combined TERS-investigations of lipids and human cellsJOURNAL OF RAMAN SPECTROSCOPY, Issue 10 2009R. Böhme Abstract Supported lipid structures and human cells (human dermal derived keratinocyte, HaCaT) were investigated using tip-enhanced Raman spectroscopy (TERS) to use the high spatial resolution capabilities of TERS, which is assumed to be less than 10 nm, to determine specific components on the cell surface. As lipids are a main component of cellular membranes, the correlation of spectral properties of pure lipids with respect to the complex biological sample was investigated. Induced by dynamic structural changes as well as nanoscale effects, a particular spectral feature of the lipid TERS spectra is found to vary, and a similar spectral deviation appears among the TERS spectra measured on the cell. Modifications of the cell surface alone cannot cause such behaviour. In contrast to soft lipid agglomerates, the cells were fixed and therefore hampered for intrinsic structural changes. Hence, the main contribution for the cell TERS spectra variation results from nanoscale effects, determined by different spectral characteristics compared to conventional Raman spectroscopy. The present results demonstrate the capability of TERS to provide a detailed and fast insight into the composition of the cell surface, even allowing the detection of single components. Copyright © 2009 John Wiley & Sons, Ltd. [source] How does the color influence figure and shape formation, grouping, numerousness and reading?OPHTHALMIC AND PHYSIOLOGICAL OPTICS, Issue 5 2010The role of chromatic wholeness, fragmentation Abstract In this work it is suggested that color induces phenomenal wholeness, part-whole organization and fragmentation. The phenomenal wholeness subsumes the set of its main attributes: homogeneity, continuity, univocality, belongingness, and oneness. If color induces wholeness, it can also induce fragmentation. Therefore, in order to understand the role played by color within the process of part-whole organization, color is used both as a wholeness and as a fragmentation tool, thus operating synergistically or antagonistically with other wholeness processes. Therefore, color is expected to influence figure-ground segregation, grouping, shape formation and other visual processes that are related to the phenomenal wholeness. The purpose of this study is to rate the influence of color in inducing whole and part-whole organization and, consequently, in determining the perception of figure-ground segregation, grouping, shape formation, numerousness evaluation and time reading. We manipulated experimental conditions by using equiluminant colors to favor or break (parcel-out) the wholeness of objects like geometrical composite figures and words. The results demonstrated that color is aimed, among other psychological and biological purposes, at: (1) relating each chromatic component of an object, thus favoring the emergence of the whole object; (2) eliciting a part-whole organization, whose components are interdependent; (3) eliciting fragments and then breaking up the whole and favoring the emergence of single components. Wholeness, part-whole organization and fragmentation can be considered as three further purposes of color. [source] ON THE CHANGE POINT OF THE MEAN RESIDUAL LIFE OF SERIES AND PARALLEL SYSTEMSAUSTRALIAN & NEW ZEALAND JOURNAL OF STATISTICS, Issue 1 2010Yan Shen Summary This paper considers the mean residual life in series and parallel systems with independent and identically distributed components and obtains relationships between the change points of the mean residual life of systems and that of their components. Compared with the change point for single components, should it exists, the change point for a series system occurs later. For a parallel system, however, the change point is located before that for the components, if it exists at all. Moreover, for both types of systems, the distance between the change points of the mean residual life for systems and for components increases with the number of components. These results are helpful in the determination of optimal burn-in time and related decision making in reliability analysis. [source] Prediction of Band Profiles of Mixtures of Bradykinin and Kallidin from Data Acquired by Competitive Frontal AnalysisBIOTECHNOLOGY PROGRESS, Issue 3 2003Dongmei Zhou The competitive adsorption isotherms of two closely related peptides, bradykinin and kallidin, were measured by frontal analysis on a Zorbax SB-C18 microbore column. An aqueous soluton at 20% acetonitrile (0.1% TFA) was used as the mobile phase. The competitive isotherm data were fitted to four different models: Langmuir, Bilangmuir, Langmuir-Freundlich, and Toth. These data fitted best to a Bilangmuir isotherm model. The influence of the pressure on the retention factors of the two peptides was found to be small and was not investigated in detail. The band profiles of large samples of the single components and of their mixtures were recorded. The overloaded profiles calculated using either the equilibrium-dispersive or POR model are in excellent agreement with the experimental profiles in all cases. Our results confirm that the competitive isotherm data derived from mixtures may suffice for a reasonably accurate prediction of the band profiles of all mixtures of the two components, provided their composition is close to 1/1. [source] | ||||||||||||||||||||||