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Simple Tool (simple + tool)
Selected AbstractsA Simple Tool for Teaching Flap Design with Digital ImagesDERMATOLOGIC SURGERY, Issue 12 2001Daniel Berg MD Background. Defects created by excision or Mohs micrographic surgery must be analyzed and surgical options including flaps must be considered. Teaching flap design to dermatology trainees is often done at the bedside of the patient with the trainee describing or marking a proposed flap. Open discussion of the options in this way is sometimes unnerving for the patient. Blackboard discussions or drawings are limited in their realism. Objective. To describe a rapid, simple method using commonly available software to allow a trainee to draw and redraw a proposed flap on a digital image of the defect without the time and cost of printing. Methods. We describe a feature in the widely used presentation program Microsoft PowerPoint which can be used to draw on an imported digital image in various colors. Results. A digital photograph taken at the bedside can quickly be loaded into PowerPoint and viewed as a full-screen picture on a computer. Using an electronic pen, multiple lines can be drawn and erased on the picture, allowing surgical planning and teaching away from the bedside. Conclusion. Design and analysis of potential incision lines for a flap can be done quickly using a digital image and commonly available software, allowing a new option for teaching flap design. [source] Using disease risk estimates to guide risk factor interventions: field test of a patient workbook for self-assessing coronary riskHEALTH EXPECTATIONS, Issue 1 2002J. Michael Paterson MSc Objective,To assess the feasibility and acceptability of a patient workbook for self-assessing coronary risk. Design,Pilot study, with post-study physician and patient interviews. Setting and subjects,Twenty southern Ontario family doctors and 40 patients for whom they would have used the workbook under normal practice conditions. Interventions,The study involved convening two sequential groups of family physicians: the first (n=10) attended focus group meetings to help develop the workbook (using algorithms from the Framingham Heart Study); the second (n=20) used the workbook in practice with 40 patients. Follow-up interviews were by interviewer-administered questionnaire. Main outcome measures,Physicians' and patients' opinions of the workbook's format, content, helpfulness, feasibility, and potential for broad application, as well as patients' perceived 10-year risk of a coronary event measured before and after using the workbook. Results,It took an average of 18 minutes of physician time to use the workbook: roughly 7 minutes to introduce it to patients, and about 11 minutes to discuss the results. Assessments of the workbook were generally favourable. Most patients were able to complete it on their own (78%), felt they had learned something (80%) and were willing to recommend it to someone else (98%). Similarly, 19 of 20 physicians found it helpful and would use it in practice with an average of 18% of their patients (range: 1,80%). The workbook helped to correct misperceptions patients had about their personal risk of a coronary event over the next 10 years (pre-workbook (mean (SD) %): 35.2 (16.9) vs. post-workbook: 17.3 (13.5), P < 0.0001; estimate according to algorithm: 10.6 (7.6)). Conclusions,Given a simple tool, patients can and will assess their own risk of CHD. Such tools could help inform otherwise healthy individuals that their risk is increased, allowing them to make more informed decisions about their behaviours and treatment. [source] Refinement of an osteoporosis risk-assessment questionnaire for use in community pharmacyINTERNATIONAL JOURNAL OF PHARMACY PRACTICE, Issue 5 2008Lee Ser Poh pharmacy practice advanced student Objective To explore the influence of bone mineral density (BMD) tests in osteoporosis risk categorisation in community pharmacies, and to develop a simple tool for pharmacists to use as a pre-BMD test screen. Method A secondary data analysis was conducted on the responses of 193 participants to a risk-assessment questionnaire, used in previous osteoporosis research that included a BMD test. To explore the impact of the BMD test on pharmacists' categorisation of risk, the researchers made an independent assessment based on responses of the questionnaire. The influence of risk factors on BMD scores/bone status was explored using multiple and logistic regression respectively. Key findings A total of responses of 193 participants were available for study, with 113 in the BMD group and 80 from the non-BMD group. In the BMD group, both researchers and pharmacists identified a similar proportion of patients in the moderate/high-risk category when BMD results were incorporated in the risk assessments (X2 = 0.78, degrees of freedom (df) = 1, 0.3 < P < 0.5). A statistically significant difference in risk categorisation was found between the pharmacists and researchers in the non-BMD group (X2 = 23.9, df = 1, P < 0.001). Risk factors identified to be significantly affecting BMD and of use for identifying patients at high risk for osteopenia/osteoporosis were age, weight, postmenopause and absence of hormone replacement therapy (HRT). These four factors were used to construct a simple risk index to guide pharmacists' initial risk categorisation. Conclusion The findings of this study suggested that BMD testing may increase the effectiveness of risk assessments and enhance the screening procedures in the community pharmacy. The simple risk index could serve as a pre-BMD test screen, with a BMD test recommended when necessary. A refined risk-assessment questionnaire could serve to guide pharmacists in directing individualised counselling and advice for at-risk patients, through identification of modifiable risk factors and conditions. [source] Security Zones and New York City's Shrinking Public SpaceINTERNATIONAL JOURNAL OF URBAN AND REGIONAL RESEARCH, Issue 1 2010JEREMY NÉMETH Abstract Urban scholars lament the loss of public space due to heightened security and behavioral controls borne of economic priorities and anti-terror concerns after September 11th 2001. Owners and managers of government buildings, banks and courthouses have closed streets and fitted the surrounding space with concrete barriers, bollards and moat-like structures to prevent potential terror attacks. These are reasonable protections in emergency situations, but, as threat levels fall, these zones fail to incorporate a diversity of users, privatizing the space for those with security clearance. The ubiquity of these zones encourages us to consider them as a new type of land use. To test this statement, we describe the results of site visits to two high-profile New York City neighborhoods (one with numerous civic buildings, the other populated with corporate headquarters). Using a simple tool we developed, we find that 27% of aggregate non-building area in the two districts is now in a security zone. Interestingly, the percentage of space within each district that can be classed as a security zone is reasonably similar, providing insight into the way in which terror targets are internally and externally defined and justified. We argue that this new type of land use is an important and permanent feature of twenty-first century global cities. Résumé Les chercheurs en sciences urbaines regrettent la perte d'espace public, incriminant souvent les contrôles accrus de sécurité et de comportement suscités par des priorités économiques ou des préoccupations anti-terroristes depuis le 11 septembre 2001. Propriétaires et gestionnaires de bâtiments publics, banques et tribunaux ont fermé des rues et équipé l'espace environnant d'obstacles en béton, de plots et de quasi-fossés afin de parer aux attaques terroristes potentielles. Ces protections sont normales en situations d'urgence, mais lorsque la menace décroît, les zones concernées ne parviennent pas à diversifier leurs usagers, l'espace étant réservé aux détenteurs de droits d'accès. L'ubiquité de ces zones pousse à les considérer comme un nouveau type d'occupation des sols. Pour vérifier cette affirmation, nous présentons les résultats de visites dans deux quartiers éminents de New York, l'un regroupant de nombreux bâtiments publics, l'autre une multitude de sièges sociaux. Au moyen d'un outil simple développé par nos soins, nous constatons que 27% de la surface cumulée non bâtie dans les deux secteurs sont désormais dans une zone sécurisée. Il faut noter que, dans chaque secteur, la proportion de l'espace qui peut être classé en zone sécurisée est relativement similaire, donnant un éclairage sur la façon dont les cibles terroristes sont définies et justifiées sur les plans intérieur et extérieur. Selon nous, ce nouveau type d'occupation des sols constitue un caractère important et permanent des villes planétaires du xxie siècle. [source] Development of a simple scoring tool in the primary care setting for prediction of recurrent falls in men and women aged 65 years and over living in the communityJOURNAL OF CLINICAL NURSING, Issue 7 2009Jean Woo Aim., We documented the number of falls and falls risk profile over two years to derive a falls risks prediction score. Background., Simple falls risk assessment tools not requiring equipment or trained personnel may be used as a first step in the primary care setting to identify older people at risk who may be referred for further falls risk assessment in special clinics. Design., Survey. Method., Men (n = 1941) and 1949 women aged 65 years and over living in the community were followed up for two years to document the number of falls. Information was collected regarding demography, socioeconomic status, medical history, functional limitations, lifestyle factors and psychosocial functioning. Measurements include body mass index, grip strength and stride length. Logistic regression was used to determine significant predictions of falls and to calculate predictive scores. Result., Twelve factors in men and nine factors in women were used to construct a risk score. The AUC of the receiver operating characteristic curve was >0·70 for both men and women and a cut off score of ,8 gave sensitivity and specificity values between 60,78%. The factors included chronic disease, drugs, functional limitation, lifestyle, education and psychosocial factors. When applied to future predictions, only low energy level and clumsiness in both hands in men and feeling downhearted in women, were significant factors. Conclusions., A risk assessment tool with a cut off score of ,8 developed from a two-year prospective study of falls may be used in the community setting as an initial first step for screening out those at low risk of falls. Relevance to clinical practice., A simple tool may be used in the community to screen out those at risk for falls, concentrating trained healthcare professionals' time on detailed falls assessment and intervention for those classified as being at risk. [source] Tropical storm impact in Central AmericaMETEOROLOGICAL APPLICATIONS, Issue 1 2006Sabino Palmieri Abstract In this study of tropical storm impacts in Central America, the relationship between physical variables (available in ,real time') and damage is explored, and a simple tool for early approximate evaluation of the impact is developed. Land track and energy dissipation appear as the most interesting parameters that modulate the hurricane impact. Because of the difficulty of attaching a monetary estimate to the damage caused in a large number of cases (as is required in a statistical approach), an ,Impact Index' based on the logarithm of casualties is introduced. Thereafter, within a subset of events in which damage in monetary terms is known, a rough link between damage and the Impact Index is derived. Shortly after a new event, as soon as land track and energy dissipation are known, either by means of an empirical equation or using a contour graph, the Impact Index may be determined. Another empirical equation allows a rough estimate of damage in monetary units, but because this estimate is based on a limited number of cases, it must be treated with caution. The methodology is tested for a small set of independent cases. Vulnerability to tropical cyclones depends not only on natural factors but also on sociopolitical conditions. A coupled sociological and environmental approach is believed to be the best way to improve the early impact estimate methodology. Copyright © 2006 Royal Meteorological Society. [source] Psychosocial factors and shoulder symptom development among workersAMERICAN JOURNAL OF INDUSTRIAL MEDICINE, Issue 1 2009Caroline K. Smith MPH Abstract Background Shoulder injuries are a common cause of pain and discomfort. Many work-related factors have been associated with the onset of shoulder symptoms. The psychosocial concepts in the demand,control model have been studied in association with musculoskeletal symptoms but with heterogeneous findings. The purpose of this study was to assess the relationship between the psychosocial concepts of the demand,control model and the incidence of shoulder symptoms in a working population. Methods After following 424 subjects for approximately 1 year, 85 incident cases were identified from self-reported data. Cox proportional hazards modeling was used to assess the associations between shoulder symptoms and demand,control model quadrants. Results Cases were more likely to be female and report other upper extremity symptoms at baseline (P,<,0.05). From the hazard models, being in either a passive or high strain job quadrant was associated with the incidence of shoulder symptoms. Hazard ratios were 2.17, 95% CI 1.02,4.66 and 2.19, 95% CI 1.08,4.42, respectively. Conclusions Using self-reporting to determine demand,control quadrants was successful in identifying subjects at risk of developing work-related shoulder symptoms. Research is needed to determine if this relationship holds with clinically diagnosed shoulder and other upper extremity musculoskeletal disorders. This may be part of a simple tool for assessing risk of developing these UEMSDs. Am. J. Ind. Med. 52:57,68, 2009. © 2008 Wiley-Liss, Inc. [source] Generalized dynamic linear models for financial time seriesAPPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY, Issue 1 2001Patrizia Campagnoli Abstract In this paper we consider a class of conditionally Gaussian state-space models and discuss how they can provide a flexible and fairly simple tool for modelling financial time series, even in the presence of different components in the series, or of stochastic volatility. Estimation can be computed by recursive equations, which provide the optimal solution under rather mild assumptions. In more general models, the filter equations can still provide approximate solutions. We also discuss how some models traditionally employed for analysing financial time series can be regarded in the state-space framework. Finally, we illustrate the models in two examples to real data sets. Copyright © 2001 John Wiley & Sons, Ltd. [source] Efficient suppression of murine arthritis by combined anticytokine small interfering RNA lipoplexesARTHRITIS & RHEUMATISM, Issue 8 2008Maroun Khoury Objective Blocking tumor necrosis factor (TNF) effectively inhibits inflammation and joint damage in rheumatoid arthritis (RA), but 40% of RA patients respond only transiently or not at all to the current anti-TNF biotherapies. The purpose of this study was to develop an alternative targeted therapy for this subgroup of RA patients. As proof of concept, we tested the efficiency of an RNA interference (RNAi),based intervention that targets proinflammatory cytokines in suppressing murine collagen-induced arthritis (CIA). Methods Two synthetic short interfering RNA (siRNA) sequences were designed for each of the proinflammatory cytokines interleukin-1 (IL-1), IL-6, and IL-18. Their silencing specificity was assessed according to lipopolysaccharide-induced messenger RNA expression in J774.1 mouse macrophages as compared with control siRNA. For in vivo administration, siRNA were formulated as lipoplexes with the RPR209120/DOPE liposome and a carrier DNA and were injected intravenously (0.5 mg/kg) into DBA/1 mice with CIA. Results Weekly injections of anti,IL-1, anti,IL-6, or anti,IL-18 siRNA-based lipoplexes significantly reduced the incidence and severity of arthritis, abrogating joint swelling and destruction of cartilage and bone, both in the preventative and the curative settings. The most striking therapeutic effect was observed when the 3 siRNA were delivered in combination. The siRNA lipoplex cocktail reduced all pathologic features of RA, including inflammation, joint destruction, and the Th1 response, and overall parameters of RA were improved as compared with anti-TNF siRNA lipoplex,based treatment. Conclusion Our results present a novel option for in vivo RNAi-based antiinflammatory immunotherapy. Our findings indicate that intravenous administration of a lipoplex cocktail containing several anticytokine siRNA is a promising novel antiinflammatory therapy for RA, as well as a useful and simple tool for understanding the pathophysiology of RA and for evaluating new therapeutic candidates. [source] Intended plans for breastfeeding duration: a simple tool to predict breastfeeding outcomeACTA PAEDIATRICA, Issue 3 2003AM Vogel Prenatal intended duration of breastfeeding has been shown to be a powerful predictor of breastfeeding initiation and duration. This provides a tool to establish the risks for short duration of breastfeeding. Conclusion: It is necessary to identify the factors that influence mothers' plans, and to find means to intervene effectively. [source] Response simulation and seismic assessment of highway overcrossingsEARTHQUAKE ENGINEERING AND STRUCTURAL DYNAMICS, Issue 9 2010Anastasios Kotsoglou Abstract Interaction of bridge structures with the adjacent embankment fills and pile foundations is generally responsible for response modification of the system to strong ground excitations, to a degree that depends on soil compliance, support conditions, and soil mass mobilized in dynamic response. This paper presents a general modeling and assessment procedure specifically targeted for simulation of the dynamic response of short bridges such as highway overcrossings, where the embankment soil,structure interaction is the most prevalent. From previous studies it has been shown that in this type of interaction, seismic displacement demands are magnified in the critical bridge components such as the central piers. This issue is of particular relevance not only in new design but also in the assessment of the existing infrastructure. Among a wide range of issues relevant to soil,structure interaction, typical highway overcrossings that have flexible abutments supported on earth embankments were investigated extensively in the paper. Simulation procedures are proposed for consideration of bridge-embankment interaction effects in practical analysis of these structures for estimation of their seismic performance. Results are extrapolated after extensive parametric studies and are used to extract ready-to-use, general, and parameterized capacity curves for a wide range of possible material properties and geometric characteristics of the bridge-embankment assembly. Using two instrumented highway overpasses as benchmark examples, the capacity curves estimated using the proposed practical procedures are correlated successfully with the results of explicit incremental dynamic analysis, verifying the applicability of the simple tools developed herein, in seismic assessment of existing short bridges. Copyright © 2009 John Wiley & Sons, Ltd. [source] Winners and losers of conservation policies for European eel, Anguilla anguilla: an economic welfare analysis for differently specialised eel anglersFISHERIES MANAGEMENT & ECOLOGY, Issue 2 2010M. DOROW Abstract, Recreational specialisation theory was coupled with a discrete choice experiment to understand eel, Anguilla anguilla L., angler's heterogeneity in their reaction to regulatory changes and the associated welfare changes. Differently specialised eel anglers exhibited distinct preferences for catch variables and eel angling regulations. All anglers preferred slightly to moderately stricter regulations than are currently in place; however, such policies particularly benefited casual eel anglers. In contrast, advanced eel anglers would be most penalised by highly restrictive regulations as indicated by substantial reductions in economic welfare. Aversions to stricter regulations found for advanced anglers contradicted predictions from specialisation theory. From an eel management perspective, the implementation of some simple tools such as increased minimum-size limits will reduce angling mortality on eel and simultaneously increase the welfare of anglers. By contrast, highly restrictive eel angling regulations will result in considerable economic welfare losses of several million , per year for northern Germany alone. [source] Milk Protein Analysis Using a Micro Fabricated Sieve: A Promising PossibilityJOURNAL OF FOOD SCIENCE, Issue 3 2001C.S. Rao ABSTRACT: In cheese making, proteins present in the micellar phase, i.e., ,, ,, ,, , casein and their variants, determine the yield and properties of the final product (Walsh and others 1995). The current milk prices are based on solid components, that is, fat, total protein and other solids. However, the cheese yields are extremely sensitive to variations in protein sub-components. Thus, total protein content, although a simple measure of yield, is not the most accurate one. In the future, the food industry might require simple tools to analyze protein components in a given sample of milk. Two features of such a tool, portability and accuracy, would be invaluable. In this article, a protocol for design of a micro-scale sieve for the separation of proteins is conceived. [source] WATER EXCHANGES: TOOLS TO BEAT EL NIÑO CLIMATE VARIABILITY IN IRRIGATED AGRICULTURE,JOURNAL OF THE AMERICAN WATER RESOURCES ASSOCIATION, Issue 1 2004Michael J. Scott ABSTRACT: Using a case study of the Yakima River Valley in Washington State, this paper shows that relatively simple tools can be used to forecast the impact of the El Niño phenomenon on water supplies to irrigated agriculture, that this information could be used to estimate the significantly shifted probability distribution of water shortages in irrigated agriculture during El Niño episodes, and that these shifted probabilities can be used to estimate the value of exchanges of water between crops to relieve some of the adverse consequences of such shortages under western water law. Further, recently devised water-trading tools, while not completely free under western water law to respond to forecasted El Niño episodes (ocean circulation patterns), are currently being employed during declared drought to reduce the devastating effects of water shortages in junior water districts on high valued perennial crops. Additional institutional flexibility is needed to take full advantage of climate forecasting, but even current tools clearly could prove useful in controlling the effects of climate variability in irrigated agriculture. Analysis shows the significant benefit of temporarily transferring or renting water rights from low-value to high-value crops, based on El Niño forecasts. [source] Mapping members of the Anopheles gambiae complex using climate dataPHYSIOLOGICAL ENTOMOLOGY, Issue 3 2004S. W. Lindsay Abstract., Climate is the most important factor governing the distribution of insects over large areas. Warmth and moisture are essential for most insects' reproduction, development and survival. Here, it is shown that the principal vectors of malaria in Africa, members of the Anopheles gambiae complex, flourish within specific climate envelopes. By identifying these climatic conditions empirically, using climate or environmental databases, it is possible to map the distribution and relative abundance of mosquito species, and their chromosomal forms, at continental scales. Alternatively, mathematical models based on a fundamental understanding of how mosquitoes are affected by different climate factors, such as temperature and humidity, can also be employed to map distributions. Empirical or process-driven models based on climate, or other environmental variables, provide simple tools for mapping the distribution and relative abundance of vectors at a coarse scale over large areas. [source] Proteome informatics I: Bioinformatics tools for processing experimental dataPROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 20 2006Patricia M. Palagi Dr. Abstract Bioinformatics tools for proteomics, also called proteome informatics tools, span today a large panel of very diverse applications ranging from simple tools to compare protein amino acid compositions to sophisticated software for large-scale protein structure determination. This review considers the available and ready to use tools that can help end-users to interpret, validate and generate biological information from their experimental data. It concentrates on bioinformatics tools for 2-DE analysis, for LC followed by MS analysis, for protein identification by PMF, by peptide fragment fingerprinting and by de,novo sequencing and for data quantitation with MS data. It also discloses initiatives that propose to automate the processes of MS analysis and enhance the quality of the obtained results. [source] The influence of cognitive impairment on health-related quality of life in neurological diseaseACTA NEUROPSYCHIATRICA, Issue 1 2010Alex J. Mitchell Mitchell AJ, Kemp S, Benito-León J, Reuber M. The influence of cognitive impairment on health-related quality of life in neurological disease. Background: Cognitive impairment is the most consistent neurological complication of acquired and degenerative brain disorders. Historically, most focus was on dementia but now has been broadened to include the important construct of mild cognitive impairment. Methods: Systematic search and review of articles linked quality of life (QoL) and cognitive complications of neurological disorders. We excluded QoL in dementia. Results: Our search identified 249 publications. Most research examined patients with brain tumours, stroke, epilepsy, head injury, Huntington's disease, motor neuron disease, multiple sclerosis and Parkinson's disease. Results suggested that the majority of patients with epilepsy, motor neuron disease, multiple sclerosis, Parkinson's disease, stroke and head injury have subtle cognitive deficits early in their disease course. These cognitive complaints are often overlooked by clinicians. In many cases, the cognitive impairment is progressive but it can also be relapsing-remitting and in some cases reversible. Despite the importance of severe cognitive impairment in the form of dementia, there is now increasing recognition of a broad spectrum of impairment, including those with subclinical or mild cognitive impairment. Even mild cognitive difficulties can have functional and psychiatric consequences,especially when they are persistent and untreated. Specific cognitive deficits such an inattention, dysexecutive function and processing speed may affect a number of quality of life (QoL) domains. For example, cognitive impairment influences return to work, interpersonal relationships and leisure activities. In addition, fear of future cognitive decline may also impact upon QoL. Conclusions: We recommend further development of simple tools to screen for cognitive impairments in each neurological condition. We also recommend that a thorough cognitive assessment should be a part of routine clinical practice in those caring for individuals with neurological disorders. [source] | |||||||||||||||||||