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Similar Mass (similar + mass)
Selected AbstractsPRECLINICAL STUDY: Route of administration affects the ability of naltrexone to reduce amphetamine-potentiated brain stimulation reward in ratsADDICTION BIOLOGY, Issue 4 2009Mark S. Todtenkopf ABSTRACT Opioid receptor antagonism has been shown to attenuate behavioral and neurochemical effects of amphetamine in humans and rodents. The effects of acute (oral or subcutaneous) or extended-release naltrexone (XR-NTX) were tested on the reward-enhancing effects of amphetamine using the intracranial self-stimulation (ICSS) paradigm. Acute exposure to drugs of abuse reduces the locus of rise (LOR) in the ICSS procedure, reflecting enhanced brain stimulation reward (BSR). Rats were treated once a day with naltrexone orally (PO; 5.0 mg/kg) or subcutaneously (SC; 0.5 mg/kg) for four consecutive days and tested with D-amphetamine (0.5 mg/kg, intraperitoneal) in the ICSS paradigm 30 minutes later on days 1 and 4. Separate groups of rats received XR-NTX (50 mg/kg, SC) or placebo microspheres (similar mass to XR-NTX, SC) on day 0 and tested with D-amphetamine in the ICSS paradigm on days 4, 14, 21, 28 and 41 after administration. Naltrexone plasma concentrations were determined for each amphetamine testing session using liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). In rats pretreated with naltrexone acutely, amphetamine-potentiated BSR did not differ from vehicle-pretreated rats on either day 1 or day 4 (25,30% decrease in LOR). In XR-NTX-pretreated rats, amphetamine-potentiated BSR was reduced by 64 and 70% on days 4 and 14, respectively, compared to placebo microsphere-treated controls. This effect dissipated by day 21. Naltrexone plasma concentrations were comparable across all treatment groups (14,30 ng/ml) on days 1, 4 and 14. In summary, an extended-release formulation of naltrexone results in significant attenuation of psychostimulant-enhanced BSR that is not observed with acute naltrexone. [source] Chick provisioning rates and growth in Blacklbrowed Albatross Diomedea melanophris and Grey-headed Albatross D. chrysostoma at Bird Island, South GeorgiaIBIS, Issue 4 2000NICOLAS HUIN We compared the parental division of labour and the pattern and rate of parental provisioning by two sympatric species of albatross of similar mass and breeding timetable but differing in diet and in the duration of chick-rearing. Using electronic weighing platforms inside artificial nests, we recorded chick mass of Black-browed Albatross and Grey-headed Albatross at Bird Island, South Georgia every 10 minutes for both species in 1993 and 1994 and for each species in two other years between 1990 and 1996. The chick mass data (nearly one million weighings) were used to calculate meal mass (over 5000 meals) and intervals between meals. Adult birds were fitted with radio-transmitters which allowed each meal to be allocated to the appropriate parent. The combination of meal mass and foraging trip duration were used to calculate provisioning rates for chicks and individual adults. Overall, Black-browed Albatrosses delivered significantly lighter meals (569 g) than Grey-headed Albatrosses (616 g) but more frequently (every 2.07 days and 2.50 days respectively). Thus combining foraging trip data for both parents, Black-browed Albatross chicks received a meal every 1.22 days compared with 1.26 days for Greyheaded Albatross. These rates did not differ significantly. The contribution of each sex of each species in chick provisioning fluctuated between years, being similar in some years or biased towards males in others. Chicks of both species that failed to fledge received smaller, less frequent meals than successful chicks. In 1990 and 1994, Black-browed Albatross chick provisioning rates were lower than in 1992 and 1993. In 1990, both meal mass and trip duration were affected, but only in 1994 was trip duration longer. Greyheaded Albatross chick provisioning rate was lower in 1994 than in other years but trip duration was longer. In each species, significant changes in meal mass and trip duration occurred within the chick-rearing period. Chick provisioning rates invariably declined before chicks attained their peak mass. For both species, chick growth rates and peak and fledging mass, but not fledging age, were affected by differences in provisioning rate. [source] The 2dF-SDSS LRG and QSO survey: QSO clustering and the L,z degeneracyMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 2 2008J. DaÂngela ABSTRACT We combine the quasi-stellar object (QSO) samples from the 2dF QSO Redshift Survey (2QZ) and the 2dF-Sloan Digital Sky Survey luminous red galaxy (LRG) and QSO Survey (2dF-SDSS LRG and QSO, hereafter 2SLAQ) in order to investigate the clustering of z, 1.5 QSOs and measure the correlation function (,). The clustering signal in redshift-space and projected along the sky direction is similar to that previously obtained from the 2QZ sample alone. By fitting functional forms for ,(,, ,), the correlation function measured along and across the line of sight, we find, as expected, that ,, the dynamical infall parameter and ,0m, the cosmological density parameter, are degenerate. However, this degeneracy can be lifted by using linear theory predictions under different cosmological scenarios. Using the combination of the 2QZ and 2SLAQ QSO data, we obtain: ,QSO(z= 1.5) = 0.60+0.14,0.11, ,0m= 0.25+0.09,0.07 which imply a value for the QSO bias, b(z= 1.4) = 1.5 ± 0.2. The combination of the 2QZ with the fainter 2SLAQ QSO sample further reveals that QSO clustering does not depend strongly on luminosity at fixed redshift. This result is inconsistent with the expectation of simple ,high peaks' biasing models where more luminous, rare QSOs are assumed to inhabit higher mass haloes. The data are more consistent with models which predict that QSOs of different luminosities reside in haloes of similar mass. By assuming ellipsoidal models for the collapse of density perturbations, we estimate the mass of the dark matter haloes which the QSOs inhabit as ,3 × 1012 h,1 M,. We find that this halo mass does not evolve strongly with redshift nor depend on QSO luminosity. Assuming a range of relations which relate halo to black hole mass, we investigate how black hole mass correlates with luminosity and redshift, and ascertain the relation between Eddington efficiency and black hole mass. Our results suggest that QSOs of different luminosities may contain black holes of similar mass. [source] The clustering of narrow-line AGN in the local UniverseMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 2 2006Cheng Li ABSTRACT We have analysed the clustering of ,90 000 narrow-line active galactic nuclei (AGN) drawn from the Data Release 4 (DR4) of the Sloan Digital Sky Survey. Our analysis addresses the following questions. (i) How do the locations of galaxies within the large-scale distribution of dark matter influence ongoing accretion on to their central black holes? (ii) Is AGN activity triggered by interactions or mergers between galaxies? We compute the cross-correlation between AGN and a reference sample of galaxies drawn from the DR4. We compare this to results for control samples of inactive galaxies matched simultaneously in redshift, stellar mass, concentration, velocity dispersion and mean stellar age, as measured by the 4000-Å break strength. We also compare near-neighbour counts around AGN and around the control galaxies. On scales larger than a few Mpc, AGN have almost the same clustering amplitude as the control sample. This demonstrates that AGN host galaxies and inactive control galaxies populate dark matter haloes of similar mass. On scales between 100 kpc and 1 Mpc, AGN are clustered more weakly than the control galaxies. We use mock catalogues constructed from high-resolution N -body simulations to interpret this antibias, showing that the observed effect is easily understood if AGN are preferentially located at the centres of their dark matter haloes. On scales less than 70 kpc, AGN cluster marginally more strongly than the control sample, but the effect is weak. When compared to the control sample, we find that only one in 100 AGN has an extra neighbour within a radius of 70 kpc. This excess increases as a function of the accretion rate on to the black hole, but it does not rise above the few per cent level. Although interactions between galaxies may be responsible for triggering nuclear activity in a minority of nearby AGN, some other mechanism is required to explain the activity seen in the majority of the objects in our sample. [source] A test of three hypotheses for ovariole number determination in the grasshopper Romalea micropteraPHYSIOLOGICAL ENTOMOLOGY, Issue 3 2010BENJAMIN J. TAYLOR Ovariole number in insects determines potential fecundity and can be influenced by genes, environmental conditions during development and parental effects. In the present study, three hypotheses are tested for ovariole number determination in the grasshopper Romalea microptera (Beauvois), which exhibits both intra- and interpopulation variation in ovariole number. In hypothesis 1, variation in ovariole number is a result of genetic variation. In hypothesis 2, ovariole number is influenced by nutrition during development. In hypothesis 3, ovariole number is influenced by maternal nutritional status. Females from four treatments are compared: low-food, high-food, daughters of low-food, and daughters of high-food. There is a relationship between parent and offspring ovariole number despite different environments, supporting hypothesis 1. Also, ovariole numbers are slightly, but significantly lower in individuals fed a low-food diet compared with a high-food diet, supporting hypothesis 2. Hypothesis 3 is not supported: starved and well-fed females produce eggs of similar mass, as well as offspring with similar numbers of ovarioles, suggesting that the nutritional status of mothers does not influence offspring mass or offspring ovariole number. The results imply that genetic variation and developmental conditions determine ovariole number in this species but maternal environment does not. These results conflict with previous studies of ovariole determination in grasshoppers and locusts. [source] Supermassive black hole merger rates: uncertainties from halo merger theoryMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 4 2006Adrienne L. Erickcek ABSTRACT The merger of two supermassive black holes is expected to produce a gravitational-wave signal detectable by the Laser Interferometer Space Antenna(LISA). The rate of supermassive-black-hole mergers is intimately connected to the halo merger rate, and the extended Press-Schechter (EPS) formalism is often employed when calculating the rate at which these events will be observed by LISA. This merger theory is flawed and provides two rates for the merging of the same pair of haloes. We show that the two predictions for the LISA supermassive-black-hole-merger event rate from EPS merger theory are nearly equal because mergers between haloes of similar masses dominate the event rate. An alternative merger rate may be obtained by inverting the Smoluchowski coagulation equation to find the merger rate that preserves the Press,Schechter halo abundance, but these rates are only available for power-law power spectra. We compare the LISA event rates derived from the EPS merger formalism to those derived from the merger rates obtained from the coagulation equation and find that the EPS LISA event rates are 30 per cent higher for a power spectrum spectral index that approximates the full , cold dark matter result of the EPS theory. [source] | ||||||||||