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Significant Stabilization (significant + stabilization)

Distribution by Scientific Domains

Chemistry	50%

Selected Abstracts

Anthraquinones as Artificial DNA Building Blocks

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 13 2008
Nicolas Bouquin
Abstract Synthesis and properties of oligodeoxynucleotides containing anthraquinone-derived building blocks with flexible linkers are described. Starting from the 1,4-, 1,5-, 1,8- and 2,6-dihydroxyanthraquinone isomers, the corresponding phosphoramidites were prepared and incorporated into oligonucleotides. The site of linker attachment was found to be of critical importance for hybrid stability. Whereas the 2,6-isomer led to a significant stabilization, all other isomers had a negative effect on the stability of the duplex. Spectroscopic studies showed that the anthraquinones behave as fluorescence quenchers. Models of anthraquinone-modified double-stranded hybrids are proposed. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source]

Görtler vortices in Falkner,Skan flows with suction and blowing

INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 3 2008
O. John E. MatssonArticle first published online: 15 MAY 200
Abstract In this paper, we use nonlinear calculations to study curved boundary-layer flows with pressure gradients and self-similar suction or blowing. For an accelerated outer flow, stabilization occurs in the linear region while the saturation amplitude of vortices is larger than for flows with a decelerating outer flow. The combined effects of boundary-layer suction and a favourable pressure gradient can give a significant stabilization of the flow. Streamwise vortices can be amplified on both concave and convex walls for decelerated Falkner,Skan flow with an overshoot in the velocity profile. The disturbance amplitude is generally lower far downstream compared with profiles without overshoot. Copyright © 2007 John Wiley & Sons, Ltd. [source]

Dediazoniation of 1-naphthalenediazonium tetrafluoroborate in aqueous acid and in micellar solutions

INTERNATIONAL JOURNAL OF CHEMICAL KINETICS, Issue 6 2008
Carlos Bravo-Diaz
We have measured the rates and product yields of dediazoniation of 1-naphthalenediazonium (1ND) tetrafluoroborate in the presence and absence of sodium dodecyl sulfate (SDS) micellar aggregates by employing a combination of UV,vis spectroscopy and high-performance liquid chromatography (HPLC) measurements. Kinetic data were obtained by a derivatization procedure with product yields were determined by HPLC. HPLC chromatograms show that in aqueous acid and in micellar solutions only one dediazoniation product is formed in significant quantities, 1-naphthol (NOH), and the observed rate constants (kobs) are the same when 1ND loss is monitored spectrometrically and when NOH formation is monitored by HPLC. Activation parameters were obtained both in the presence and absence of SDS micellar aggregates. In both the systems, the enthalpies of activation are high and the entropies of activation are positive. The enthalpy of activation in the absence of SDS is very similar to that in the presence of SDS micelles, but the entropy of activation is lower by a factor of 4. As a consequence, SDS micelles speed up the thermal decomposition of 1ND and increase kobs by a factor of 1.5 when [SDS] = 0.02 M. In contrast, results obtained in the presence of complexing systems such as crown ethers and polyethers show significant stabilization of the parent arenediazonium ions. Kinetic and HPLC data are consistent with the heterolytic DN + AN mechanism that involves the rate-determining fragmentation of the arenediazonium ion into a very reactive phenyl cation that reacts competitively with available nucleophiles. © 2008 Wiley Periodicals, Inc. Int J Chem Kinet 40: 301,309, 2008 [source]

Stabilization of vinyl chloride/vinylidene chloride copolymers using N-substituted maleimides,

JOURNAL OF VINYL & ADDITIVE TECHNOLOGY, Issue 3 2006
Bob A. Howell
As a consequence of their excellent barrier properties, vinyl chloride/vinylidene chloride copolymers have long been prominent in the flexible packaging market. While these polymers possess a number of superior characteristics, they tend to undergo thermally induced degradative dehydrochlorination at process temperatures. This degradation must be controlled to permit processing of the polymers. Three series of N-substituted maleimides (N -alkyl-, N -aralkyl-, and N -aryl-) have been synthesized, characterized spectroscopically, and evaluated as potential stabilizers for a standard vinyl chloride/vinylidene chloride (85 wt%) copolymer. As surface blends with the polymer, these compounds are ineffective as stabilizers. However, significant stabilization may be achieved by pretreatment of the polymer with N-substituted maleimides. The most effective stabilization of the polymer is afforded by N -aralkyl- or N -arylmaleimides, most notably, N -benzylmaleimide and N -(p -methoxyphenyl)maleimide. J. VINYL. ADDIT. TECHNOL. 12:88,97, 2006. © 2006 Society of Plastics Engineers. [source]