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Significant Regional Variation (significant + regional_variation)
Selected AbstractsChanges in the food of British Barn Owls (Tyto alba) between 1974 and 1997MAMMAL REVIEW, Issue 2 2000R. Alasdair Love ABSTRACT Comparison of the results of a 1993,97 Barn Owl Tyto alba pellet survey with those of a similar survey from 1956,74 showed that Barn Owl diet had changed significantly. The primary differences were a widespread decrease in the percentage of Common Shrew Sorex araneus, combined with an increase in Pygmy Shrew Sorex minutus. The percentage of Wood and Yellow-necked mice Apodemus sylvaticus and A. flavicollis and Bank Vole Clethrionomys glareolus in the diet also increased. Changes in Barn Owl diet since 1974 were independent of land-class group, but were dependent upon region. This was due primarily to a large increase in the percentage of Apodemus spp. in Eastern England. Whilst the percentage of Pygmy Shrew in Barn Owl diet showed significant regional variation, there was no significant variation between land-class groups. The diversity of Barn Owl diet increased between 1974 and 1997, although it was still lower in 1997 than earlier in the century. This increase was dependent upon region, but independent of land-class group. The combined results of both surveys showed significant interland-class group variation in dietary diversity. Changes in diet are discussed in relation to the intensification of agriculture and other changes in land management since the 1970s. The effects on Barn Owls of these changes in prey abundance are discussed, particularly in relation to the decline in Barn Owl numbers during the twentieth century. [source] D-MELD, a Simple Predictor of Post Liver Transplant Mortality for Optimization of Donor/Recipient MatchingAMERICAN JOURNAL OF TRANSPLANTATION, Issue 2 2009J. B. Halldorson Numerous donor and recipient risk factors interact to influence the probability of survival after liver transplantation. We developed a statistic, D-MELD, the product of donor age and preoperative MELD, calculated from laboratory values. Using the UNOS STAR national transplant data base, we analyzed survival for first liver transplant recipients with chronic liver failure from deceased after brain death donors. Preoperative D-MELD score effectively stratified posttransplant survival. Using a cutoff D-MELD score of 1600, we defined a subgroup of donor,recipient matches with significantly poorer short- and long-term outcomes as measured by survival and length of stay (LOS). Avoidance of D-MELD scores above 1600 improved results for subgroups of high-risk patients with donor age ,60 and those with preoperative MELD ,30. D-MELD ,1600 accurately predicted worse outcome in recipients with and without hepatitis C. There is significant regional variation in average D-MELD scores at transplant, however, regions with larger numbers of high D-MELD matches do not have higher survival rates. D-MELD is a simple, highly predictive tool for estimating outcomes after liver transplantation. This statistic could assist surgeons and their patients in making organ acceptance decisions. Applying D-MELD to liver allocation could eliminate many donor/recipient matches likely to have inferior outcome. [source] Epidemiology of cholangiocarcinoma: An update focusing on risk factorsCANCER SCIENCE, Issue 3 2010Hai-Rim Shin (Cancer Sci 2010; 101: 579,585) Cholangiocarcinoma is relatively rare, but high incidence rates have been reported in Eastern Asia, especially in Thailand. The etiology of this cancer of the bile ducts appears to be mostly due to specific infectious agents. In 2009, infections with the liver flukes, Clonorchis sinensis or Opistorchis viverrini, were both classified as carcinogenic to humans by the International Agency for Research on Cancer for cholangiocarcinoma. In addition, a possible association between chronic infection with hepatitis B and C viruses and cholangiocarcinoma was also noted. The meta-analysis of published literature revealed the summary relative risks of infection with liver fluke (both Opistorchis viverrini and Clonorchis sinensis), hepatitis B virus, and hepatitis C virus to be 4.8 (95% confidence interval [95% CI]: 2.8,8.4), 2.6 (95% CI: 1.5,4.6), and 1.8 (95% CI: 1.4,2.4), respectively , liver fluke infection being the strongest risk factor for cholangiocarcinoma. Countries where human liver fluke infection is endemic include China, Korea, Vietnam, Laos, and Cambodia. The number of infected persons with Clonorchis sinensis in China has been estimated at 12.5 million with considerable variations among different regions. A significant regional variation in Opistorchis viverrini prevalence was also noted in Thailand (average 9.6% or 6 million people). The implementation of a more intensive preventive and therapeutic program for liver fluke infection may reduce incidence rates of cholangiocarcinoma in endemic areas. Recently, advances have been made in the diagnosis and management of cholangiocarcinoma. Although progress on cholangiocarcinoma prevention and treatment has been steady, more studies related to classification and risk factors will be helpful to develop an advanced strategy to cure and prevent cholangiocarcinoma. [source] THE RESPONSE OF PARTIALLY DEBRIS-COVERED VALLEY GLACIERS TO CLIMATE CHANGE: THE EXAMPLE OF THE PASTERZE GLACIER (AUSTRIA) IN THE PERIOD 1964 TO 2006GEOGRAFISKA ANNALER SERIES A: PHYSICAL GEOGRAPHY, Issue 4 2008ANDREAS KELLERER-PIRKLBAUER ABSTRACT. Long-term observations of partly debris-covered glaciers have allowed us to assess the impact of supra-glacial debris on volumetric changes. In this paper, the behaviour of the partially debris-covered, 3.6 km2 tongue of Pasterze Glacier (47°05,N, 12°44,E) was studied in the context of ongoing climate changes. The right part of the glacier tongue is covered by a continuous supra-glacial debris mantle with variable thicknesses (a few centimetres to about 1 m). For the period 1964,2000 three digital elevation models (1964, 1981, 2000) and related debris-cover distributions were analysed. These datasets were compared with long-term series of glaciological field data (displacement, elevation change, glacier terminus behaviour) from the 1960s to 2006. Differences between the debriscovered and the clean ice parts were emphasised. Results show that volumetric losses increased by 2.3 times between the periods 1964,1981 and 1981,2000 with significant regional variations at the glacier tongue. Such variations are controlled by the glacier emergence velocity pattern, existence and thickness of supra-glacial debris, direct solar radiation, counter-radiation from the valley sides and their changes over time. The downward-increasing debris thickness is counteracting to a compensational stage against the common decrease of ablation with elevation. A continuous debris cover not less than 15 cm in thickness reduces ablation rates by 30,35%. No relationship exists between glacier retreat rates and summer air temperatures. Substantial and varying differences of the two different terminus parts occurred. Our findings clearly underline the importance of supra-glacial debris on mass balance and glacier tongue morphology. [source] | ||||||||||