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Sinus Augmentation (sinus + augmentation)
Kinds of Sinus Augmentation Terms modified by Sinus Augmentation Selected AbstractsThe Buccofacial Wall of Maxillary Sinus: An Anatomical Consideration for Sinus AugmentationCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2009Hun-Mu Yang DDS ABSTRACT Purpose: This study aimed to quantify the thickness of the buccofacial wall of the maxillary sinus where sinus augmentations are often performed. Materials and Methods: Fourteen sites located 15 and 20 mm superior to the anatomical cervical line (named as groups H15 and H20, respectively) and along the long axes of the mid and the interproximal of two premolars and two molars were measured from 74 Korean hemiface cadavers. Results: The buccofacial wall of the maxillary sinus was thinnest at the area between the maxillary second premolar and first molar in groups H15 and H20. The lowest mean thickness was 1.2 mm in both groups. The walls were thicker in males than in females, with statistically significant gender differences found at four and two sites on the anterior horizontal reference in groups H15 and H20, respectively. However, the thickness did not differ significantly with age or laterality. Incomplete septa were found in seven of the 74 specimens, and they were present in the area between the first and second molars in six (86%) of these cases. Conclusions: These observations indicate that anatomical characteristics of the buccofacial wall thickness of the maxillary sinus need to be considered when performing a window opening procedure for sinus augmentation. [source] Combining Scaffolds and Osteogenic Cells in Regenerative Bone Surgery: A Preliminary Histological Report in Human Maxillary Sinus AugmentationCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2009Carlo Mangano DDS ABSTRACT Purpose: The following case series evaluated the maxillary sinus augmentation responses to tissue-engineered bone graft obtained by a culture of autogenous osteoblasts seeded on polyglycolic,polylactic scaffolds and calcium phosphate. Materials and Methods: Sinus floor augmentation was performed bilaterally in five patients (mean age 58.4 years) with tissue-engineered bone (test site , Oral Bone®, BioTissue, Freiburg, Germany) or calcium phosphate (control site , Biocoral, Novaxa Spa, Milan, Italy). Biopsies were harvested 6 months after sinus augmentation for histometric evaluation. Volumetric measurements were taken at baseline and 6 months after the surgical procedure. Results: The mean of vertical bone gain was 6.47 ± 1.39 mm and 9.14 ± 1.19 mm to test and control sites, respectively. The histological sections depicted mature bone with compact and cancellous areas. All biopsies contained varying percentages of newly formed bone and marrow spaces. The mean of bone tissue in the grafted area was 37.32 ± 19.59% and 54.65 ± 21.17% for tissue-engineered bone and calcium phosphate, respectively. Conclusion: Within the limits of the present report, the histological data in humans confirmed that tissue-engineered bone and calcium phosphate allowed newly formed bone after maxillary sinus augmentation. [source] Mesenchymal stem cells and platelet-rich plasma enhance bone formation in sinus grafting: a histomorphometric study in minipigsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 6 2008Francesco Pieri Abstract Objectives: Autologous, allogenic, and alloplastic materials for sinus augmentation have specific drawbacks, which has stimulated an ongoing search for new materials and tissue-engineering constructs. We investigated whether mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) seeded on a fluorohydroxyapatite (FH) scaffold can improve bone formation and bone-to-implant contact (BIC) in maxillary sinus grafting. Material and Methods: Bilateral sinus augmentation procedures were performed in eight minipigs. MSCs, PRP, and FH scaffold (test site) or FH alone (control site) were grafted in each maxillary sinus. Distal to the osteotomy, one dental implant per sinus was placed in the grafting material through the facial sinus wall. The animals were killed 3 months after grafting, and block sections of the implant sites were harvested and prepared for histomorphometric analysis. Results: After 12 weeks, a significant increase in bone formation occurred in the test sites compared with the control sites (42.51%versus 18.98%; p=0.001). In addition, BIC was significantly greater in the test sites compared with the control sites in the regenerated area (23.71%versus 6.63%; p=0.028). Conclusions: These findings show that sinus augmentation with MSCs,PRP, combined with FH may enhance bone formation and osseointegration of dental implants compared with FH alone in minipigs. [source] Tissue factor: a mini-reviewJOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, Issue 3 2007Valéry Daubie Abstract Tissue factor (TF) is historically known as the trigger of the coagulation cascade. This integral membrane glycoprotein forms a ternary complex with factor VIIa (FVIIa) and zymogen factor (FX), which is then activated to factor Xa (FXa). The latter cleaves prothrombin into thrombin (FIIa), which in turn activates fibrinogen in fibrin monomers. What is less known is its additional non-haemostatic roles in inflammation, tumour growth and angiogenesis. This aspect will be developed here. TF, as a transmembrane protein, has a signalling effect requiring FVIIa. TF,FVIIa complex activates G protein-coupled receptor protease-activated receptor 2 (PAR-2) and therefore modulates various cellular processes, such as cell proliferation and survival, gene transcription and protein translation. In this review we will first highlight, using recent structural data, the ,potentially' active domain able to modulate the triggered intracellular response. We also will focus on the still emerging and promising results deciphering the diverse locations in which TF appears. We conclude with a description of an emerging and atypical use of tissue factor in platelet gel surgery for sinus augmentation. Copyright © 2007 John Wiley & Sons, Ltd. [source] Quantitation of Mandibular Symphysis Volume as a Source of Bone GraftingCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2 2010Fernando Verdugo DDS ABSTRACT Background: Autogenous intramembranous bone graft present several advantages such as minimal resorption and high concentration of bone morphogenetic proteins. A method for measuring the amount of bone that can be harvested from the symphysis area has not been reported in real patients. Purpose: The aim of the present study was to intrasurgically quantitate the volume of the symphysis bone graft that can be safely harvested in live patients and compare it with AutoCAD® (version 16.0, Autodesk, Inc., San Rafael, CA, USA) tomographic calculations. Materials and Methods: AutoCAD software program quantitated symphysis bone graft in 40 patients using computerized tomographies. Direct intrasurgical measurements were recorded thereafter and compared with AutoCAD data. The bone volume was measured at the recipient sites of a subgroup of 10 patients, 6 months post sinus augmentation. Results: The volume of bone graft measured by AutoCAD averaged 1.4 mL (SD 0.6 mL, range: 0.5,2.7 mL). The volume of bone graft measured intrasurgically averaged 2.3 mL (SD 0.4 mL, range 1.7,2.8 mL). The statistical difference between the two measurement methods was significant. The bone volume measured at the recipient sites 6 months post sinus augmentation averaged 1.9 mL (SD 0.3 mL, range 1.3,2.6 mL) with a mean loss of 0.4 mL. Conclusion: AutoCAD did not overestimate the volume of bone that can be safely harvested from the mandibular symphysis. The use of the design software program may improve surgical treatment planning prior to sinus augmentation. [source] The Buccofacial Wall of Maxillary Sinus: An Anatomical Consideration for Sinus AugmentationCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2009Hun-Mu Yang DDS ABSTRACT Purpose: This study aimed to quantify the thickness of the buccofacial wall of the maxillary sinus where sinus augmentations are often performed. Materials and Methods: Fourteen sites located 15 and 20 mm superior to the anatomical cervical line (named as groups H15 and H20, respectively) and along the long axes of the mid and the interproximal of two premolars and two molars were measured from 74 Korean hemiface cadavers. Results: The buccofacial wall of the maxillary sinus was thinnest at the area between the maxillary second premolar and first molar in groups H15 and H20. The lowest mean thickness was 1.2 mm in both groups. The walls were thicker in males than in females, with statistically significant gender differences found at four and two sites on the anterior horizontal reference in groups H15 and H20, respectively. However, the thickness did not differ significantly with age or laterality. Incomplete septa were found in seven of the 74 specimens, and they were present in the area between the first and second molars in six (86%) of these cases. Conclusions: These observations indicate that anatomical characteristics of the buccofacial wall thickness of the maxillary sinus need to be considered when performing a window opening procedure for sinus augmentation. [source] Combining Scaffolds and Osteogenic Cells in Regenerative Bone Surgery: A Preliminary Histological Report in Human Maxillary Sinus AugmentationCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2009Carlo Mangano DDS ABSTRACT Purpose: The following case series evaluated the maxillary sinus augmentation responses to tissue-engineered bone graft obtained by a culture of autogenous osteoblasts seeded on polyglycolic,polylactic scaffolds and calcium phosphate. Materials and Methods: Sinus floor augmentation was performed bilaterally in five patients (mean age 58.4 years) with tissue-engineered bone (test site , Oral Bone®, BioTissue, Freiburg, Germany) or calcium phosphate (control site , Biocoral, Novaxa Spa, Milan, Italy). Biopsies were harvested 6 months after sinus augmentation for histometric evaluation. Volumetric measurements were taken at baseline and 6 months after the surgical procedure. Results: The mean of vertical bone gain was 6.47 ± 1.39 mm and 9.14 ± 1.19 mm to test and control sites, respectively. The histological sections depicted mature bone with compact and cancellous areas. All biopsies contained varying percentages of newly formed bone and marrow spaces. The mean of bone tissue in the grafted area was 37.32 ± 19.59% and 54.65 ± 21.17% for tissue-engineered bone and calcium phosphate, respectively. Conclusion: Within the limits of the present report, the histological data in humans confirmed that tissue-engineered bone and calcium phosphate allowed newly formed bone after maxillary sinus augmentation. [source] Internal Sinus Manipulation (ISM) Procedure: A Technical ReportCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 3 2007Jason M. Yamada DDS ABSTRACT Background, The sinus augmentation procedure has facilitated dental implant treatment in the posterior maxilla where there is insufficient bone for implant placement. A modified Caldwell-Luc, lateral window technique can be applied in most cases needing sinus augmentation in order to create a larger bone volume. However, treatment morbidity can be a concern, especially in the form of postoperative swelling due to surgical trauma. Vertical augmentation using osteotomes has also been selected as a choice of treatment due to less invasive surgery and less postoperative trauma. Although the osteotome technique enables the surgeon to raise the sinus membrane internally through an implant osteotomy site, the quantity and predictability of bone augmentation can be limiting due to the elasticity of the Schneiderian sinus membrane, difficulty of the membrane to separate from the floor as well as the inability to have direct tactile access to "peel" the membrane off of the floor. Purpose, The objective of this report is to present a new, minimally invasive sinus augmentation technique, called the Internal Sinus Manipulation (ISM) procedure, which has been developed to facilitate sinus floor augmentation while reducing treatment morbidity and yet have direct tactile access to raise the membrane off of the sinus floor. Surgical Technique, Access to the Schneiderian sinus membrane is achieved without perforation of the membrane through a conventional osteotomy drilling procedure alone or combined with osteotome technique, followed by reflection of the membrane utilizing special ISM instrumentation and bone graft procedure laterally and vertically through the osteotomy site. A planned implant is then placed. Conclusion, The Internal Sinus Manipulation procedure can be used as an alternative treatment modality for sinus augmentation as compared to the external lateral window technique while reducing postoperative morbidity for the patients who need implant treatment in posterior maxillary areas. [source] Optimal microvessel density from composite graft of autogenous maxillary cortical bone and anorganic bovine bone in sinus augmentation: influence of clinical variablesCLINICAL ORAL IMPLANTS RESEARCH, Issue 2 2010Pablo Galindo-Moreno Abstract Objectives: The objectives of this study were to assess the microvessel density (MVD) of intra-sinus grafts after 6 months of wound healing and to study the relationship between revascularization processes and patient clinical variables and habits. Material and methods: We performed 45 maxillary sinus augmentations with different implant placements in 25 consecutive patients, obtaining bone cores of the grafted area for histological, histomorphometric and immunohistochemical study. Biopsies were also taken from pristine bone in the posterior maxilla (control). Results: All implants survived at 24 months. Biopsies of sinus augmentation areas showed significantly greater remodeling activity vs. pristine bone, with significantly more osteoid lines. The morphometry study revealed 34.88±15.2% vital bone, 32.02±15.1% non-mineralized tissue and 33.08±25.4% remnant anorganic bovine bone particles. The number of CD34-positive vessels was 86.28±55.52/mm2 in graft tissue vs. 31.52±13.69/mm2 in native tissue (P=0.002, Mann,Whitney U=46). The larger amount of non-mineralized tissue in grafts was directly correlated with a higher MVD (r=0.482, P=0.0001, Pearson's test). MVD was affected by the presence of periodontitis or tobacco and alcohol consumption. Conclusion: The angiogenesis and revascularization obtained by this type of graft achieve adequate tissue remodeling for osseointegration and are influenced by periodontal disease and tobacco or alcohol consumption. To cite this article: Galindo-Moreno P, Padial-Molina M, Fernández-Barbero JE, Mesa F, Rodríguez-Martínez D, O'Valle F. Optimal microvessel density from composite graft of autogenous maxillary cortical bone and anorganic bovine bone in sinus augmentation: influence of clinical variables. Clin. Oral Impl. Res. 21, 2010; 221,227 doi: 10.1111/j.1600-0501.2009.01827.x [source] Sinus augmentation analysis revised: the gradient of graft consolidationCLINICAL ORAL IMPLANTS RESEARCH, Issue 10 2009Dieter Busenlechner Abstract Objective: Graft consolidation follows a gradient that reflects the properties of bone substitutes at sites of sinus augmentation. Here we present an analytical method to investigate the process of graft consolidation taking the distance from the maxillary host bone into account. Material and methods: We therefore evaluated histological specimens, 6 and 12 weeks after the sinus of minipigs was augmented with Bio-Oss®, a deproteinized bovine bone mineral, and Ostim®, an aqueous paste of synthetic nanoparticular hydroxyapatite. A curve was drawn that represents the changes in histomorphometric parameters within a given distance from the maxillary host bone. Results: Based on this curve, three regions of interest were defined: R1 (0,1 mm) the bridging distance where new bone is laid onto the host bone, R2 (2,3 mm) a region of osteoconduction where new bone exclusively grows on the biomaterial, R3 (4,5 mm) and a region of osteoconduction where bone formation has reached its maximal extension. Qualitative and quantitative analysis of the three regions can reveal differences in graft consolidation, depending on the bone substitutes and the observation period [Bone volume (BV) per tissue volume after 6 weeks: R1: 19±8.4% for Bio-Oss® and 42.9±13.2% for Ostim® (P=0.03), R2: 3±2.4% for Bio-Oss® and 14.7±9.5% for Ostim® (P=0.03), R3: 5±4.1% for Bio-Oss® and 5.3±5.3% for Ostim® (P=0.86). BV per tissue volume after 12 weeks: R1: 38.0±13.3% for Bio-Oss® and 53.3±6.6 for Ostim® (P=0.04), R2: 14±12.2 for Bio-Oss® and 26.4±11 for Ostim® (P=0.18), R3: 6.6±7 for Bio-Oss® and 10.7±5.8 for Ostim® (P=0.32) after 12 weeks]. Conclusion: Based on the graft consolidation gradient, the impact of bone substitutes to modulate the process of bone formation and the kinetic of degradation within a distinct region of the augmented sinus can be investigated. [source] Injectable calcium phosphate cement as a graft material for maxillary sinus augmentation: an experimental pilot studyCLINICAL ORAL IMPLANTS RESEARCH, Issue 6 2008Ali Aral Abstract Objectives: The aim of the present study was to evaluate the efficiency of injectable CaP cement as a graft material around dental implants in the maxillary sinus augmentation procedure. Material and methods: Bilateral sinus augmentation process was carried out in three sheep and two implants were inserted during the same session. Out of a total of 12 installed implants, eight belonged to the so-called experimental group. In the experimental group, injectable CaP cement was used as augmentation material while autologous bone served as control. Results: Histological examination revealed that newly formed bone surrounded the cement completely without an intervening fibrous tissue layer. Following a healing period of 12 weeks, mean bone-to-implant contact (BIC) values in the experimental and control groups were 36±5 and 37±3, respectively. The percentage of BIC was comparable with other experimental sinus augmentation studies. Further, it appeared that the thickness of the cortical bone that covered the outer surface of the maxillary sinus was <2,3 mm, which affected the primary stability of the implants negatively. Conclusion: CaP cement is indeed effective to stimulate bone formation in the sinus elevation procedure. Nevertheless, additional improvements in the cement composition are required to allow final clinical utilization of the material. [source] Osteotomy and membrane elevation during the maxillary sinus augmentation procedureCLINICAL ORAL IMPLANTS RESEARCH, Issue 5 2008A comparative study: piezoelectric device vs. conventional rotative instruments Abstract Objectives: The aim of the present study was to investigate in a randomized-controlled clinical trial the performance of rotary instruments compared with a piezoelectric device during maxillary sinus floor elevation. Materials and methods: Thirteen patients who required a bilateral maxillary sinus augmentation for implant,prosthetic rehabilitation were included in this study. A within-patient control study was carried out. The osteotomy for sinus access was performed on one side of the maxilla using the piezosurgery (test sites) and on the other side using conventional rotary diamond burs (control sites). The parameters recorded were as follows: bony window length (L), bony window height (H), bone thickness (T) and osteotomy area (A) , calculated by multiplying L and H. In addition, the time necessary for the osteotomy and sinus membrane elevation as well as the number of surgical complications were calculated. Results: The mean length and height of the bone window were similar in both groups. The osteotomy area (A) obtained by multiplying L and H was wider in the control group (151.2 ± 20.4 mm2) compared with the test group (137 ± 24.2 mm2). The time necessary for the osteotomy and the sinus membrane elevation with conventional instruments was 10.2 ± 2.4 min, while with the piezoelectric device it was 11.5 ± 3.8 min. Moreover, membrane perforation occurred in 30% of the maxillary sinuses in the test group and in 23% of the control group. None of the differences observed between the two groups reached a level of significance. Conclusions: Within the limits of the present study, it may be concluded that piezosurgery and conventional instruments did not show any differences in the clinical parameters investigated for the maxillary sinus floor elevation. [source] Freeze-dried bone for maxillary sinus augmentation in sheepCLINICAL ORAL IMPLANTS RESEARCH, Issue 6 2002Part II: Biomechanical findings Abstract: This study examines the biomechanical loading capacity of dental implants placed in the posterior maxilla in conjunction with subantral augmentation with either homogeneous demineralized freeze-dried bone from sheep (s-DFDB) or heterogeneous demineralized freeze-dried human bone (h-DFDB) as grafting material in sheep. In 36 adult female mountain sheep, the Schneiderian membrane was elevated extraorally in both maxillary sinuses, and two titanium plasma-flame-sprayed cylindrical implants were inserted in each lateral antral wall. Three groups of 18 maxillary sinuses each were augmented with s-DFDB, h-DFDB and autogenous bone from the illiac crest, respectively. In the remaining 18 sinuses, the subantral hollow space was left empty. Pull-out tests were carried out after intervals of 12, 16 and 26 weeks. The mean pull-out force needed, irrespective of time, was 259.3 N in the empty control group, 356.7 N in the group augmented with autogenous bone, 278.1 N in the test group augmented with h-DFDB and 365.2 N in the group augmented with s-DFDB, revealing no significant difference between the individual groups (P > 0.05). The implants of the group augmented with autogenous bone showed an increase in the mean pull-out force from 223.8 N after 12 weeks to 523.7 N after 26 weeks. The nonaugmented control group yielded values of 248 N after 12 weeks, which rose to 269.8 N at the last test, while the values of the h-DFDB group increased from 275.4 N to 325.4 N. The highest initial pull-out values were obtained in the s-DFDB group. They amounted to 310.5 N after 12 weeks and rose to 481.4 N after 26 weeks. Time thus proved to have a significant influence on the pull-out forces (P = 0.014) with a statistically proven linear trend (P = 0.007). The findings of this experimental study indicate that the use of homogeneous DFDB in one-stage sinus lift procedures results in a mechanical loading capacity of implants comparable to that achieved by autogenous cancellous bone from the iliac crest. In contrast, the use of heterogenous-DFDB resulted in only slightly higher pull-out forces than those observed in the nonaugmented control group after 26 weeks. [source] The Buccofacial Wall of Maxillary Sinus: An Anatomical Consideration for Sinus AugmentationCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2009Hun-Mu Yang DDS ABSTRACT Purpose: This study aimed to quantify the thickness of the buccofacial wall of the maxillary sinus where sinus augmentations are often performed. Materials and Methods: Fourteen sites located 15 and 20 mm superior to the anatomical cervical line (named as groups H15 and H20, respectively) and along the long axes of the mid and the interproximal of two premolars and two molars were measured from 74 Korean hemiface cadavers. Results: The buccofacial wall of the maxillary sinus was thinnest at the area between the maxillary second premolar and first molar in groups H15 and H20. The lowest mean thickness was 1.2 mm in both groups. The walls were thicker in males than in females, with statistically significant gender differences found at four and two sites on the anterior horizontal reference in groups H15 and H20, respectively. However, the thickness did not differ significantly with age or laterality. Incomplete septa were found in seven of the 74 specimens, and they were present in the area between the first and second molars in six (86%) of these cases. Conclusions: These observations indicate that anatomical characteristics of the buccofacial wall thickness of the maxillary sinus need to be considered when performing a window opening procedure for sinus augmentation. [source] Optimal microvessel density from composite graft of autogenous maxillary cortical bone and anorganic bovine bone in sinus augmentation: influence of clinical variablesCLINICAL ORAL IMPLANTS RESEARCH, Issue 2 2010Pablo Galindo-Moreno Abstract Objectives: The objectives of this study were to assess the microvessel density (MVD) of intra-sinus grafts after 6 months of wound healing and to study the relationship between revascularization processes and patient clinical variables and habits. Material and methods: We performed 45 maxillary sinus augmentations with different implant placements in 25 consecutive patients, obtaining bone cores of the grafted area for histological, histomorphometric and immunohistochemical study. Biopsies were also taken from pristine bone in the posterior maxilla (control). Results: All implants survived at 24 months. Biopsies of sinus augmentation areas showed significantly greater remodeling activity vs. pristine bone, with significantly more osteoid lines. The morphometry study revealed 34.88±15.2% vital bone, 32.02±15.1% non-mineralized tissue and 33.08±25.4% remnant anorganic bovine bone particles. The number of CD34-positive vessels was 86.28±55.52/mm2 in graft tissue vs. 31.52±13.69/mm2 in native tissue (P=0.002, Mann,Whitney U=46). The larger amount of non-mineralized tissue in grafts was directly correlated with a higher MVD (r=0.482, P=0.0001, Pearson's test). MVD was affected by the presence of periodontitis or tobacco and alcohol consumption. Conclusion: The angiogenesis and revascularization obtained by this type of graft achieve adequate tissue remodeling for osseointegration and are influenced by periodontal disease and tobacco or alcohol consumption. To cite this article: Galindo-Moreno P, Padial-Molina M, Fernández-Barbero JE, Mesa F, Rodríguez-Martínez D, O'Valle F. Optimal microvessel density from composite graft of autogenous maxillary cortical bone and anorganic bovine bone in sinus augmentation: influence of clinical variables. Clin. Oral Impl. Res. 21, 2010; 221,227 doi: 10.1111/j.1600-0501.2009.01827.x [source] | ||||||||||