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Selected AbstractsData Preparation for Real-time High Quality Rendering of Complex ModelsCOMPUTER GRAPHICS FORUM, Issue 3 2006Reinhard Klein The capability of current 3D acquisition systems to digitize the geometry reflection behaviour of objects as well as the sophisticated application of CAD techniques lead to rapidly growing digital models which pose new challenges for interaction and visualization. Due to the sheer size of the geometry as well as the texture and reflection data which are often in the range of several gigabytes, efficient techniques for analyzing, compressing and rendering are needed. In this talk I will present some of the research we did in our graphics group over the past years motivated by industrial partners in order to automate the data preparation step and allow for real-time high quality rendering e.g. in the context of VR-applications. Strength and limitations of the different techniques will be discussed and future challenges will be identified. The presentation will go along with live demonstrations. [source] Splitting a large software repository for easing future software evolution,an industrial experience report,JOURNAL OF SOFTWARE MAINTENANCE AND EVOLUTION: RESEARCH AND PRACTICE, Issue 2 2009Marco Glorie Abstract Philips Medical Systems produces medical diagnostic imaging products, such as magnetic resonance, X-ray and computed tomography systems. The software of these devices is complex, has been evolving for several decades and is currently a multi-MLOC monolithic software repository. In this paper we report on splitting a single software repository into multiple smaller repositories so that these can be developed independently, easing the software's evolution. For splitting the single software repository, we set up two experiments that involve well-known analysis techniques, namely formal concept analysis and clustering. Because of the sheer size of the monolithic software repository, we also propose to use a ,leveled approach', which implies that the analysis technique is applied in several iterations, whereby in some iterations only part of the application is subjected to the analysis technique. Unfortunately, both analysis techniques failed to produce an acceptable partitioning of the monolithic software repository, even if they are combined with our newly proposed leveled approach. We provide a number of valuable lessons learned, which might prevent others from falling into the same pitfalls. Copyright © 2009 John Wiley & Sons, Ltd. [source] TRP channels as therapeutic targets: hot property, or time to cool down?NEUROGASTROENTEROLOGY & MOTILITY, Issue 8 2006G. A. Hicks Abstract,Transient receptor potential (TRP) channels are involved in a wide range of processes ranging from osmoregulation, thermal, chemical and sensory signalling, and potentially in the pathophysiology associated with several diseases. Patents for TRPV1 antagonists alone span diseases ranging across chronic pain, neuropathies, headache, bladder disorders, irritable bowel syndrome (IBS), gastro-oesophageal reflux disease (GORD), and cough amongst others. Most research is currently focused around those TRP channels involved in sensory processes, with the neurogastroenterology and motility field playing a major role, for example, through recent discoveries of differential roles for TRPV receptor subtypes in chemosensitivity and mechanosensitivity of visceral afferents. At this time, however, the understanding of the role of even TRPV1, let alone most of the other TRP channels in disease pathophysiology is only just beginning, and although enthusiasm around the therapeutic potential for modulators of these channels is understandable, based largely upon the experience of the effects of natural ligands, such as capsaicin, the sheer size and complexity of the TRP family as a whole must serve as a warning against expecting too much too soon from drug discovery efforts. [source] Remote visualisation of Labrador convection in large oceanic datasetsATMOSPHERIC SCIENCE LETTERS, Issue 4 2005L. J. West Abstract The oceans relinquish O(1PW) of heat into the atmosphere at high latitudes, the lion's share of which originates in localised ,hotspots' of violent convective mixing, but despite their small horizontal scale,O(10,100km),these features may penetrate deeply into the thermocline and are vital in maintaining the Atlantic Meridional Overturning Circulation (MOC). Accurate modelling of the MOC, therefore, requires a large-scale numerical model with very fine resolution. The global high-resolution ocean model, Ocean Circulation Climate Advanced Model (OCCAM) has been developed and run at the Southampton Oceanography Centre (SOC) for many years. It was configured to resolve the energetic scales of oceanic motions, and its output is stored at the Manchester Supercomputer Centre. Although this community resource represents a treasure trove of potential new insights into the nature of the world ocean, it remains relatively unexploited for a number of reasons, not the least of which is its sheer size. A system being developed at SOC under the auspices of the Grid for Ocean Diagnostics, Interactive Visualisation and Analysis (GODIVA) project makes the remote visualisation of very large volumes of data on modest hardware (e.g. a laptop with no special graphics capability) a present reality. The GODIVA system is enabling the unresolved question of oceanic convection and its relationship to large-scale flows to be investigated; a question that lies at the heart of many current climate change issues. In this article, one aspect of the GODIVA is presented, and used to locate and visualise regions of convective mixing in the OCCAM Labrador Sea. Copyright © 2006 Royal Meteorological Society [source] | ||||||||||