Sensitive Areas (sensitive + area)

Distribution by Scientific Domains


Selected Abstracts


Habitat models of bird species' distribution: an aid to the management of coastal grazing marshes

JOURNAL OF APPLIED ECOLOGY, Issue 5 2000
T. P. Milsom
1.,Coastal grazing marshes comprise an important habitat for wetland biota but are threatened by agricultural intensification and conversion to arable farmland. In Britain, the Environmentally Sensitive Area (ESA) scheme addresses these problems by providing financial incentives to farmers to retain their grazing marshes, and to follow conservation management prescriptions. 2.,A modelling approach was used to aid the development of management prescriptions for ground-nesting birds in the North Kent Marshes ESA. This ESA contains the largest area of coastal grazing marsh remaining in England and Wales (c. 6500 ha) and supports nationally important breeding populations of lapwing Vanellus vanellus and redshank Tringa totanus. 3.,Counts of ground-nesting birds, and assessments of sward structure, surface topography and wetness, landscape structure and sources of human disturbance were made in 1995 and again in 1996, on 19 land-holdings with a combined area of c. 3000 ha. The land-holdings varied from nature reserves at one extreme to an intensive dairy farm at the other. 4.,Models of relationship between the presence or absence of ground-nesting birds and the grazing marsh habitat in each of c. 430 marshes were constructed using a generalized linear mixed modelling (GLMM) method. This is an extension to the conventional logistic regression approach, in which a random term is used to model differences in the proportion of marshes occupied on different land-holdings. 5.,The combined species models predicted that the probability of marshes being occupied by at least one ground-nesting species increased concomitantly with the complexity of the grass sward and surface topography but decreased in the presence of hedgerows, roads and power lines. 6.,Models were also prepared for each of the 10 most widespread species, including lapwing and redshank. Their composition differed between species. Variables describing the sward were included in models for five species: heterogeneity of sward height tended to be more important than mean sward height. Surface topography and wetness were important for waders and wildfowl but not for other species. Effects of boundaries, proximity to roads and power lines were included in some models and were negative in all cases. 7.,Binomial GLMMs are useful for investigating habitat factors that affect the distribution of birds at two nested spatial scales, in this case fields (marshes) grouped within farms. Models of the type presented in this paper provide a framework for targeting of conservation management prescriptions for ground-nesting birds at the field scale on the North Kent Marshes ESA and on lowland wet grassland elsewhere in Europe. [source]


Instrument Insufficiency and Economic Stabilisation

THE AUSTRALIAN ECONOMIC REVIEW, Issue 3 2006
Roger J. Bowden
Recently concerns have been raised in New Zealand about the effectiveness of monetary policy in controlling inflation while avoiding damage to the economy from high exchange rates. This review examines the basis for concern and identifies the problem as a failure in the primary instrument, namely the Reserve Bank's official cash rate, to adequately impact further along the term structure curve, which has become the more sensitive area for aggregate demand. Direct control over expenditure is therefore weak, and too much leeway is left to the housing and other asset markets to sustain demand in the economy. Globalisation of credit availability and financial technology have helped to blunt the policy instrument in this respect, shifting the adjustment burden on to the exchange rate. Deft management of interest and currency expectations can help, but the problem may require closer coordination and cooperation between monetary and fiscal policy, restoring a stabilisation role for the latter. [source]


2134: Arachnoid cell changes following elevated pressure and oxidative stress: new implications for optic nerve degeneration

ACTA OPHTHALMOLOGICA, Issue 2010
A NEUTZNER
Purpose The study of meningothelial cells (MCs) and their connection to optic nerve function. MCs line the arachnoid layer of the meninges and form a barrier between the CSF and the blood circulation. A previous study revealed a significantly increased proliferation of MCs in the arachnoid surrounding the optic nerve glaucoma patients. Methods To explore a possible role of these cells in the pathogenesis of diseases of the optic nerve, we studied the effect of elevated hydrostatic pressure and oxidative stress on MCs using rotenone to inhibit mitochondrial function and compared them to untreated control cells. Cell viability and proliferation were measured using a MTS-based assay. As a measure of barrier function, we assessed the endocytotic activity of MCs by fluorescence and confocal microscopy following fluorescent-latex bead uptake. Results Exposure of MCs to elevated hydrostatic pressure caused significant cellular proliferation and a dramatic decrease in endocytotic activity. Furthermore, mild oxidative stress severely inhibited endocytosis, thus negatively impacting MC barrier function. Conclusion MCs surround the optic nerve, thereby shielding it from but also conditioning the microenvironment of this sensitive area. As elevated pressure and oxidative stress occur in patients with increased intracranial pressure who have papilledema and probably in some cases of normal-tension glaucoma, these phenomena may impact the function of MCs and thus, contribute to the loss of retinal ganglion cells in the course of these and, perhaps, other optic nerve diseases. [source]


Angiolymphoid Hyperplasia with Eosinophilia Successfully Treated with a Long-Pulsed Tunable Dye Laser

DERMATOLOGIC SURGERY, Issue 3 2000
Thomas E. Rohrer MD
Background. To date, both surgical excision and laser treatments for angiolymphoid hyperplasia with eosinophilia (ALHE) have resulted in scarring. Objective. Based on the principle of selective photothermolysis, we considered employing the newer long-pulsed tunable dye laser in the treatment of ALHE, as less scarring would be expected and deeper blood vessels could be ablated. Methods. After punch biopsy specimens confirmed the diagnosis, the patient was treated on two separate occasions, 2 months apart with a long-pulsed tunable dye laser. Results. The lesions flattened after the initial treatment and resolved after a second treatment. No scarring was detectable and no recurrence was noted in follow-up after 1 year. Conclusion. We conclude that the long-pulsed tunable dye laser can be employed successfully to treat superficial lesions of ALHE, particularly in cosmetically sensitive areas. [source]


Modeling past and future alpine permafrost distribution in the Colorado Front Range

EARTH SURFACE PROCESSES AND LANDFORMS, Issue 12 2005
Jason R. Janke
Abstract Rock glaciers, a feature associated with at least discontinuous permafrost, provide important topoclimatic information. Active and inactive rock glaciers can be used to model current permafrost distribution. Relict rock glacier locations provide paleoclimatic information to infer past conditions. Future warmer climates could cause permafrost zones to shrink and initiate slope instability hazards such as debris flows or rockslides, thus modeling change remains imperative. This research examines potential past and future permafrost distribution in the Colorado Front Range by calibrating an existing permafrost model using a standard adiabatic rate for mountains (0·5 °C per 100 m) for a 4 °C range of cooler and warmer temperatures. According to the model, permafrost currently covers about 12 per cent (326·1 km2) of the entire study area (2721·5 km2). In a 4 °C cooler climate 73·7 per cent (2004·4 km2) of the study area could be covered by permafrost, whereas in a 4°C warmer climate almost no permafrost would be found. Permafrost would be reduced severely by 93·9 per cent (a loss of 306·2 km2) in a 2·0 °C warmer climate; however, permafrost will likely respond slowly to change. Relict rock glacier distribution indicates that mean annual air temperature (MAAT) was once at least some 3·0 to 4·0 °C cooler during the Pleistocene, with permafrost extending some 600,700 m lower than today. The model is effective at identifying temperature sensitive areas for future monitoring; however, other feedback mechanisms such as precipitation are neglected. Copyright © 2005 John Wiley & Sons, Ltd. [source]


Nature conservation and urban development control in the Portuguese planning system: a new impetus against old praxis?

ENVIRONMENTAL POLICY AND GOVERNANCE, Issue 5 2008
Teresa Fidelis
Abstract Natura 2000 areas bring a new incentive to assess the performance of land-use planning in protecting environmental values from the impacts of development pressures. In the last decades, urban growth and consequent environmental impacts on natural areas have been a major concern for the Portuguese land-use planning system. Sprawl around sensitive areas has been revealed to be a persistent phenomenon in spite of the increasing challenges underlying land-use plans. This article critically analyses the content of three main documents recently adopted by the Portuguese government , the ,National Strategy for Sustainable Development', the ,National Policy Programme for Spatial Planning' and the ,Sector Plan for Natura 2000' , seeking prospects to innovate future plans at lower levels in order to prevent additional pressures on natural areas. First, the article reviews the recent theoretical debate on planning for the protection of natural areas. Results evidenced by recent EU evaluation reports are used to propose a set of guidelines to evaluate planning guidance at national level. Second, it critically analyses the three planning documents, bearing in mind the main features of the planning system and the proposed guidelines. The article is concluded with a discussion of their potential, exploring whether they bring a new impetus to the role of land-use planning against an outdated and persistent praxis, or whether, on the contrary, further efforts to strengthen planning guidance remain to be formulated. Copyright © 2008 John Wiley & Sons, Ltd and ERP Environment. [source]


Is the Open Method of Coordination Appropriate for Organising Activities at European Level in Sensitive Policy Areas?

EUROPEAN LAW JOURNAL, Issue 1 2002
Caroline de la Porte
This article addresses the question of the relevance of the most recent soft policy instrument of the EU, the open method of coordination (OMC), for organising actions at European level in politically sensitive areas. In addition to describing its origins and operational principles, we will compare its application to the areas of employment and social inclusion. Two hypotheses make up the structure of the text. The first is that the discourses produced in the framework of OMC in the areas of employment and social inclusion are broad enough to cater to the different welfare models, but that the changes to be made by the Member States to be in line with the European discourses differ considerably, depending on their welfare state family and their initial situation. The second is that the form of OMC is variable, depending on policy area. Our conclusions confirm both of these hypotheses. [source]


Highway alignment optimization through feasible gates

JOURNAL OF ADVANCED TRANSPORTATION, Issue 2 2007
Min Wook Kang
Abstract An efficient optimization approach, called feasible gate (FG), is developed to enhance the computation efficiency and solution quality of the previously developed highway alignment optimization (HAO) model. This approach seeks to realistically represent various user preferences and environmentally sensitive areas and consider them along with geometric design constraints in the optimization process. This is done by avoiding the generation of infeasible solutions that violate various constraints and thus focusing the search on the feasible solutions. The proposed method is simple, but improves significantly the model's computation time and solution quality. Such improvements are demonstrated with two test examples from a real road project. [source]


Inundative release of coccinellid beetles into eucalypt plantations for biological control of chrysomelid leaf beetles

AGRICULTURAL AND FOREST ENTOMOLOGY, Issue 2 2003
Susan C. Baker
Abstract 1,Inundative augmentative releases of adult coccinellid beetles were assessed for their potential to effectively supplement biological control of outbreak populations of the Eucalyptus leaf beetle Chrysophtharta bimaculata in Eucalyptus nitens plantations. 2,Mixed groups of two species of overwintering coccinellids, Cleobora mellyi and Harmonia conformis, were collected from the field then fed three diets in the laboratory prior to release. Both species were released in the summer into two E. nitens plantations with economically damaging Chrysophtharta populations. 3,Differences between dispersal of coccinellids fed the three diets were slight; beetles brought straight out of overwintering before release were initially slower moving onto trees. 4,Numbers of coccinellids on trees in monitoring plots decreased exponentially with time, and populations had returned to prerelease levels 7 days after release. The number of coccinellids recaptured decreased with increasing distance from the release point with very few coccinellids per tree at 70 m distance. Dispersal of C. mellyi away from the release plot was slower than that of H. conformis. 5,Numbers of coccinellids on trees were significantly related to predation levels of C. bimaculata with a large decrease in the C. bimaculata population to below the economic damage threshold in plots where the numbers of coccinellids were high. 6,The results of this study suggest that inundative release of laboratory reared coccinellids is possible for biological control of C. bimaculata, although it may only be economically viable in small, environmentally sensitive areas. [source]


How patients experience psoriasis: results from a European survey

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 2005
S Fouéré
ABSTRACT Background, Most of the psoriasis that affects the European population is treated with topical preparations. Compliance rates, however, are known to be quite low. Objective, To provide an update on how psoriasis is experienced by patients and how well these patients comply with prescribed topical treatment. Methods, This was an observational and transversal survey conducted in 1281 patients with psoriasis. Patient input alone formed the basis of the study. Participants were contacted through the national psoriasis patient associations in France, the United Kingdom, Belgium, Germany and the Netherlands. Results, The study showed that 32% of the patients suffer currently from psoriasis in the face, skin folds and genital areas , areas very sensitive to topical treatments. Most of the patients (74%) considered their psoriasis as at least moderately severe, and 73% stated not to comply with their current treatment. Lack of efficacy and messiness of the treatment were the main reasons for non-compliance, an element that is especially important for the use in sensitive areas such as the face, skin folds and genitalia. Conclusion, The present survey confirmed that cosmetic acceptability is, together with efficacy and safety, a very important aspect of a successful treatment of psoriasis. [source]


Complications of fractional CO2 laser resurfacing: Four cases

LASERS IN SURGERY AND MEDICINE, Issue 3 2009
Douglas J. Fife MD
Abstract Background and Objective Fractional ablative laser therapy is a new modality which will likely be widely used due to its efficacy and limited side-effect profile. It is critical to recognize, characterize, and report complications in order to acknowledge the limits of therapeutic efficacy and to improve the safety of these devices. Study Design/Materials and Methods The photographs, treatment parameters, and clinical files of four female patients aged 54,67 who had scarring or ectropion after fractional CO2 laser resurfacing on the face or neck were carefully reviewed to search for any possible linking factors. Results Patient 1 developed erosions and swelling of the right lower eyelid 2 days postoperatively, which developed into scarring and an ectropion. Patient 2 developed linear erosions and beefy red swelling on the right side of the neck which developed into a tender, band-like scar over 1-month. Patient 3 developed stinging and yellow exudate in multiple areas of the neck 3 days postoperatively. Cultures grew methicillin-resistant Staphylococcus aureus. Despite appropriate treatment, she developed multiple areas of irregular texture and linear streaking which developed into scars. Patient 4 developed an asymptomatic patchy, soft eschar with yellowish change on the left side of the neck. Azithromycin was started, however at 2-week follow-up she had fibrotic streaking which developed into horizontal scars and a vertical platysmal band. The treatment and final outcome of each patient are described. Conclusion Scarring after fractional CO2 laser therapy may be due to overly aggressive treatments in sensitive areas (including excessive energy, density, or both), lack of technical finesse, associated infection, or idiopathic. Care should be taken when treating sensitive areas such as the eyelids, upper neck, and especially the lower neck and chest by using lower energy and density. Postoperative infections may lead to scarring and may be prevented by careful taking of history, vigilant postoperative monitoring and/or prophylactic antibiotics. Lasers Surg. Med. 41:179,184, 2009. © 2009 Wiley-Liss, Inc. [source]


Rare Earth Deposits of North America

RESOURCE GEOLOGY, Issue 4 2008
Stephen B. Castor
Abstract Rare earth elements (REE) have been mined in North America since 1885, when placer monazite was produced in the southeast USA. Since the 1960s, however, most North American REE have come from a carbonatite deposit at Mountain Pass, California, and most of the world's REE came from this source between 1965 and 1995. After 1998, Mountain Pass REE sales declined substantially due to competition from China and to environmental constraints. REE are presently not mined at Mountain Pass, and shipments were made from stockpiles in recent years. Chevron Mining, however, restarted extraction of selected REE at Mountain Pass in 2007. In 1987, Mountain Pass reserves were calculated at 29 Mt of ore with 8.9% rare earth oxide based on a 5% cut-off grade. Current reserves are in excess of 20 Mt at similar grade. The ore mineral is bastnasite, and the ore has high light REE/heavy REE (LREE/HREE). The carbonatite is a moderately dipping, tabular 1.4-Ga intrusive body associated with ultrapotassic alkaline plutons of similar age. The chemistry and ultrapotassic alkaline association of the Mountain Pass deposit suggest a different source than that of most other carbonatites. Elsewhere in the western USA, carbonatites have been proposed as possible REE sources. Large but low-grade LREE resources are in carbonatite in Colorado and Wyoming. Carbonatite complexes in Canada contain only minor REE resources. Other types of hard-rock REE deposits in the USA include small iron-REE deposits in Missouri and New York, and vein deposits in Idaho. Phosphorite and fluorite deposits in the USA also contain minor REE resources. The most recently discovered REE deposit in North America is the Hoidas Lake vein deposit, Saskatchewan, a small but incompletely evaluated resource. Neogene North American placer monazite resources, both marine and continental, are small or in environmentally sensitive areas, and thus unlikely to be mined. Paleoplacer deposits also contain minor resources. Possible future uranium mining of Precambrian conglomerates in the Elliott Lake,Blind River district, Canada, could yield by-product HREE and Y. REE deposits occur in peralkaline syenitic and granitic rocks in several places in North America. These deposits are typically enriched in HREE, Y, and Zr. Some also have associated Be, Nb, and Ta. The largest such deposits are at Thor Lake and Strange Lake in Canada. A eudialyte syenite deposit at Pajarito Mountain in New Mexico is also probably large, but of lower grade. Similar deposits occur at Kipawa Lake and Lackner Lake in Canada. Future uses of some REE commodities are expected to increase, and growth is likely for REE in new technologies. World reserves, however, are probably sufficient to meet international demand for most REE commodities well into the 21st century. Recent experience shows that Chinese producers are capable of large amounts of REE production, keeping prices low. Most refined REE prices are now at approximately 50% of the 1980s price levels, but there has been recent upward price movement for some REE compounds following Chinese restriction of exports. Because of its grade, size, and relatively simple metallurgy, the Mountain Pass deposit remains North America's best source of LREE. The future of REE production at Mountain Pass is mostly dependent on REE price levels and on domestic REE marketing potential. The development of new REE deposits in North America is unlikely in the near future. Undeveloped deposits with the most potential are probably large, low-grade deposits in peralkaline igneous rocks. Competition with established Chinese HREE and Y sources and a developing Australian deposit will be a factor. [source]


The value of observations.

THE QUARTERLY JOURNAL OF THE ROYAL METEOROLOGICAL SOCIETY, Issue 628 2007
III: Influence of weather regimes on targeting
Abstract This paper assesses the value of targeted observations over the North Atlantic Ocean for different meteorological flow regimes. It shows that during tropical cyclone activity and particularly tropical cyclone transition to extratropical characteristics, removing observations in sensitive regions, indicated by singular vectors optimized on the 2-day forecast over Europe, degrades the skill of a given forecast more so than excluding observations in randomly selected regions. The maximum downstream degradation computed in terms of spatially and temporally averaged root-mean-square error of 500 hPa geopotential height is about 13%, a value which is 6 times larger than when removing observations in randomly selected areas. The forecast impact for these selected periods, resulting from degrading the observational coverage in sensitive areas, was similar to the impact found (elsewhere in other weather forecast systems) for the observational targeting campaigns carried out over recent years, and it was larger than the average impact obtained by considering a larger set of cases covering various seasons. Copyright © 2007 Royal Meteorological Society [source]


Analysis of RET, ZEB2, EDN3 and GDNF Genomic Rearrangements in Central Congenital Hyperventilation Syndrome Patients by Multiplex Ligation-dependent Probe Amplification

ANNALS OF HUMAN GENETICS, Issue 4 2010
Alexandre Serra
Summary Central congenital hypoventilation syndrome (CCHS) is an autonomous control disease producing hypoventilation, high PaCO2, and low PaO2 during quiet sleep. The main gene variants detected in CCHS are mutations in the PHOX2b gene in up to 97% of isolated cases. However, CCHS is sometimes associated with autonomic diseases such as Hirschsprung disease (HSCR). Since genomic rearrangements in particularly sensitive areas of the RET protooncogene and/or associated genes may account for the CCHS/HSCR phenotype in patients without other detectable RET variants, the aim of the present study was to identify rearrangements in the coding sequence of RET as well as in three HSCR-associated genes (ZEB2, EDN3 and GDNF) in CCHS/HSCR patients by using Multiplex Ligation-dependent Probe Amplification (MLPA). We have screened 27 CCHS and 11 CCHS/HSCR patients for genomic rearrangements in RET, ZEB2, EDN3 and GDNF and did not identify any deletion or amplification in these four genes in all patients. We conclude that genomic rearrangements in RET are rare and were not responsible for the CCHS/HSCR phenotype in individuals without identifiable germline RET variants in our group of patients, yet this possibility cannot be excluded altogether given the size of the cohort. [source]


Analysis of RET, ZEB2, EDN3 and GDNF Genomic Rearrangements in 80 Patients with Hirschsprung Disease (Using multiplex ligation-dependent probe amplification)

ANNALS OF HUMAN GENETICS, Issue 2 2009
A. Serra
Summary Hirschsprung disease (HSCR) is transmitted in a complex pattern of inheritance and is mostly associated with variants in the RET proto-oncogene. However, RET mutations are only identified in 15,20% of sporadic HSCR cases and solely in 50% of the familial cases. Since genomic rearrangements in particularly sensitive areas of the RET proto-oncogene and/or associated genes may account for the HSCR phenotype in patients without other detectable RET variants, the aim of the present study was to identify rearrangements in the coding sequence of RET as well as in three HSCR-associated genes (ZEB2, EDN3 and GDNF) in HSCR patients by using Multiplex Ligation-dependent Probe Amplification (MLPA). We have screened 80 HSCR patients for genomic rearrangements in RET, ZEB2, EDN3 and GDNF and did not identify any deletion or amplification in these four genes in all patients. We conclude that genomic rearrangements in RET are rare and were not responsible for the HSCR phenotype in individuals without identifiable germline RET variants in our group of patients, yet this possibility cannot be excluded altogether because the confidence to identify variation in at least two percent of the individuals was only 95%. [source]


Thoroughness of skin examination by melanoma patients: Influence of age, sex and partner

AUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 3 2009
Susan L Boone
ABSTRACT The aim of this study was to determine the thoroughness of deliberate skin examination by people with a history of melanoma. Patients were randomized into one of two conditions: either to receive the brief educational and skills training intervention alone or as a couple with their spouse or cohabiting partner. Subjects recorded concerning lesions on body maps. At the 4-month visit, a total body skin examination was performed by a dermatologist blinded to the subjects' condition and to their recorded responses. The skin surface was divided according to the region's visibility during skin self-examination and sexual connotations: visible/not sexually sensitive, non-visible/not sexually sensitive and sexually sensitive. The primary point of comparison was missed lesions, defined as the difference between lesions recorded by the subjects and their partners and those recorded by the dermatologist. Among 130 participants, 56 subjects reported partner assistance while performing SSE. Participants missed more lesions in sexually sensitive areas than in the other regions. With the increasing age of the patient, the number of missed lesions in non-visible/not sexually sensitive and sexually sensitive areas decreased. Male patients assisted by female partners missed fewer lesions in all three regions than female patients assisted by male partners. In easily visible areas, male patients missed significantly fewer lesions than female patients (P = 0.01). Older couples performed more thorough partner-assisted skin examinations in non-visible and sexually sensitive areas than younger couples. Male patients who were assisted by female partners performed more thorough partner-assisted skin examinations than female patients assisted by male partners. [source]


Vitiligo-like depigmentation induced by imiquimod treatment of superficial basal cell carcinoma

AUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 3 2009
Kavita Sriprakash
ABSTRACT A 61-year-old man was treated with imiquimod 5% cream for superficial basal cell carcinoma, five times per week for 13 weeks. This resulted in vitiligo-like depigmentation and poliosis in the area of treatment. This rare side-effect has been noted in previous case reports of imiquimod treatment for both genital warts and superficial basal cell carcinoma. This highlights the importance of such a side-effect being discussed with the patient who is to be treated with imiquimod, particularly in cosmetically sensitive areas. [source]


Service user participation in diverse child protection contexts: principles for practice

CHILD & FAMILY SOCIAL WORK, Issue 4 2009
Karen Healy
ABSTRACT Promoting the participation of children and parents in child protection practice is one of the most complex and sensitive areas of social work practice. Increasingly, child protection legislation and policy in many parts of the world enshrines ideals of service user participation. Yet, with the exception of extensive discussion about family group conferencing, the principles and methods for achieving participatory practices in child protection work remain underdeveloped. We use the term ,child protection' to refer to a broad spectrum of child and family welfare services aimed at prevention of (or intervention to address) child abuse and neglect. This spectrum of services includes intensive family support, family support, domestic violence, statutory child protection and child and family advocacy services. In this paper, we present findings from the first phase of a 3-year study into participatory practice in child protection. In this paper, we present findings from a qualitative analysis of interviews with 28 child protection practitioners across five domains of child protection work. Our analysis reveals three core principles of participatory practice underpinning these practitioners' accounts as well as contextual differences among them. We conclude with a discussion of the educational implications of our findings. [source]