See Article (see + article)

Distribution by Scientific Domains


Selected Abstracts


Immunotherapy for Invasive Fungal Infections in Transplant Patients: Back to the Future?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2010
Hans H. Hirsch
For kidney transplant patients with life-threatening disseminated fungal infections and failure of modern antifungal therapies, exogenous interferon-gamma might represent an adjunct salvage therapy, but the risk-benefit ratio is not yet established. See Article by Armstrong-James et al on page 1796. [source]


Posttransplant Prophylaxis Strategies for Hepatitis B

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2010
E. Gane
Oral antivirals combined with low-dose hepatitis B immunoglobulin provide highly effective prophylaxis against recurrent hepatitis B following liver transplantation for chronic hepatitis B. See Article by Degertekin et al on page 1823. [source]


The Sleeping Giant Awakens,Liver Transplantation in China

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2010
J. Fung
The number of liver transplants in China continues to rise, but the challenge of increasing the use of donation after brain death remains daunting. See Article by Allam et al on page 1834. [source]


The Anti-LFA-1 Trial in Islet Transplantation

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2010
J. Oberholzer
The results of this small efalizumab study in islet transplantation are interesting but by no means definitive. See Article by Posselt et al on page 1870. [source]


Immunosuppressive Agents and CMV Risk in the VICTOR Study

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2010
R. K. Avery
Post-hoc analysis of the VICTOR trial data concerning immunosuppressive agents yields some anticipated and some unexpected results. See Article by ┼sberg et al on page 1881. [source]


Proinflammatory Events and HLA Antibodies: Nothing to Sneeze At

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 9 2009
K. E. Kokko
While proinflammatory events may lead to changes in HLA antibody profiles, it is not clear whether aggressive monitoring following any such event is appropriate. See Article by Locke et al on page 2136,2139. [source]


4D11: The Second Mouse?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2009
A. D. Kirk
The non-human primate experience with the human CD40-specific human monoclonal antibody 4D11 reported in this issue holds promise that this agent will be suitable for human clinical trials, provided that we remember the lessons learned from previous agents acting on this mechanism. See Article by Aoyagi et al on page 1732,1741. [source]


Is Downstaging Prior to Liver Transplantation Important in Hepatocellular Carcinoma?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2009
P. Lee
Downstaging hepatocellular carcinoma for liver transplantation is a procedure in evolution, but the results presented in this article for Yttrium-90 radioembolization are encouraging. See Article by Lewandowski et al on page 1920,1928. [source]


Lung Transplantation Outcomes: The Importance and Inadequacies of Assessing Survival

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2009
R. D. Yusen
In addition to assessing survival, comprehensive studies of donor allocation system outcomes should assess issues such as morbidity and quality of life. See Article by Titman et al on page 1640,1649. [source]


Does Early (CNI) Conversion Lead to Eternal (Renal) Salvation?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2010
G. McKenna
Early conversion from calcineurin inhibitors to m-TOR inhibitors may lead to improved renal function in liver transplant recipients, but further confirmation of the safety and efficacy is needed. See article by Masetti et al on page 2252. [source]


Prediction Model for Delayed Kidney Transplant Function: No Need for New Regulation

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2010
Stephen T. Bartlett
The proposed model to better predict the occurrence of DGF may miss the mark and further complicate the process of informed consent. See article by Irish et al on page 2279. [source]


Operational Tolerance After Liver Transplantation: Raising the Bar or Tripping Up?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2010
James F. Trotter
The randomized trial evaluating the occurrence of tolerance in liver transplant recipients reported in this issue represents an opportunity to learn lessons for future studies. See article by BenÝtez et al on page 2296. [source]


Liver Transplantation for Alcoholic Liver Disease: Knowing the Future Informs the Present

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2010
J. Neuberger
Knowing the likelihood, timing and pattern of alcohol consumption after liver transplantation allows a targeted therapeutic and behavioral approach to reducing the impact of recidivism. See article by DiMartini et al on page 2305. [source]


Editorial: Cold Machine Perfusion or Static Cold Storage of Kidneys: Why the Debate Continues

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 9 2010
W. D. Irish
The debate regarding the efficacy of cold machine perfusion versus static cold storage for prevention of delayed graft function in organs from deceased donors continues, despite the results of two well-designed clinical trials. See article by Watson et al on page 1991. [source]


Editorial: The Molecular Phenotype of Heart Transplant Biopsies

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 9 2010
C. C. Marboe
Molecular phenotyping of heart transplant biopsies could provide a better understanding of biopsy histology and cardiac dysfunction in allograft rejection. See article by Mengel et al on page 2105. [source]


Editorial: The ,Two, One, Zero' Decision: What to Do with Suboptimal Deceased Donor Kidneys

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 9 2010
R. Shapiro
While it is feasible to transplant two ECD kidneys into a single recipient, we need better data to help us decide with confidence whether a given set of kidneys should be transplanted into two patients, one patient, or not at all. See article by Esker et al on page 2000. [source]


Just How Stable Is Allograft Tolerance?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2010
R. G. Gill
In some cases, an infection may trigger allograft rejection even after putative regulatory tolerance has been established, raising the question: is allograft tolerance ever really stable? See article by Wang et al on page 1524. [source]


Does Hematuria Contraindicate Kidney Donation?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2010
B. J. Nankivell
Whether to use kidneys from donors with asymptomatic microscopic hematuria necessitates a thoughtful nephrological approach. See article by Kido et al on page 1597. [source]


Evaluating Liver Transplantation in Childhood: Is Life-Style Attainment in Adulthood the Ultimate Measure of Transplant Success?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2010
M. A. Heneghan
Overall well-being and social integration should receive more attention then they currently receive. See article by Dommergues et al on page 1643. [source]


Unfair Priority for HCC: A Problem Whose Ideal Solution Remains Unsolved

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2010
M. L. Volk
The ideal solution to priority for HCC will require better tools to predict survival benefit from liver transplantation. See article by Washburn et al on page 1652. [source]


Dimensions of Antibody-Mediated Rejection

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 7 2010
R. B. Colvin
Alloantibody is widely accepted as a major cause of acute and chronic rejection in the kidney. Development of consensus criteria in other organ transplants, such as the pancreas and heart will accelerate progress. See article by de Kort et al on page 1669. [source]


Is Extracorporeal Support Becoming the New Standard for the Preservation of DCD Grafts?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 6 2010
C. Fondevila
While normothermic extracorporeal support is a promising alternative to reduce ischemic injury in DCD grafts, further clinical studies are needed to evaluate its true impact on outcomes. See article by Rojas-Pena et al on page 1365. [source]


The Importance of Skin Cancer Prevention in Organ Transplant Patients An Editorial to Paper by Salgo: ,Switch to Sirolimus in Long-Term Renal Transplant Recipients: Reduced Premalignancies and Nonmelanoma Skin Cancer in a Controlled, Prospective, Randomized, Blinded Study'

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 6 2010
C. Mitchell
Renal transplant patients should be managed by dermatologists to prevent and manage skin cancer, a common cause of morbidity and mortality in organ transplant patients. See article by Salgo et al on page 1385. [source]


Living Donor Kidney Donation in the United States: Quo Vadis?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 6 2010
G. Danovitch
Editorial comment on the ethical concerns raised by Woodle, et al regarding a policy of preferentially allocating kidneys from non-directed living donors to facilitate paired-exchange and chain transplantation. See article by Woodle et al on page 1460. [source]


Giving Birth to an Operation: Laparoscopic Live Donor Nephrectomy with Vaginal Extraction.

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 6 2010
Is This Misconceived?
Vaginal extraction of the kidney: the start of something new or only a case report? See article by Allaf et al on page 1473. [source]


Kidneys for Sale: Whose Attitudes Matter?

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 5 2010
D. L. Segev
The nuances of public opinion towards organ markets are the least of the obstacles faced by supporters of these markets. See article by Leider and Roth on page 1221. [source]


An Ongoing Issue Concerning Facial Transplantation

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 5 2010
C. Strong
The risk of chronic rejection in facial transplantation continues to cause concern. See article by Siemionow and Gordon on page 1290. [source]


Educating Kidney Transplant Professionals and Candidates May Improve Utilization, Allocation Efficiency and Lifetime Survival

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 4 2010
K. A. Andreoni
Is the answer to more appropriate use of ECD Kidney Grafts as reviewed by Grams et al in this publication better education of transplant professionals and patients? See article by Grams et al on page 802. [source]


Antibody-Based Immunosuppression Following Liver Transplantation: The Plot Thickens

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 3 2010
J. K. Heimbach
The role of antibody-based immunosuppression in liver transplant recipients remains an area in which prospective trials are needed. See article by Moonka et al on page 590. [source]


Allograft Fibrosis,Unmasking the Players at the Dance

AMERICAN JOURNAL OF TRANSPLANTATION, Issue 2 2010
R. B. Mannon
New data suggest that the pleiotropic cytokine interleukin-6 may be a key contributor to allograft fibrosis through a complex interaction with connective tissue growth factor (CTGF), a downstream effector of TGF-beta. See article by Booth et al on page 220. [source]