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Selected AbstractsDisparity in regional and systemic circulatory capacities: do they affect the regulation of the circulation?ACTA PHYSIOLOGICA, Issue 4 2010J. A. L. Calbet Abstract In this review we integrate ideas about regional and systemic circulatory capacities and the balance between skeletal muscle blood flow and cardiac output during heavy exercise in humans. In the first part of the review we discuss issues related to the pumping capacity of the heart and the vasodilator capacity of skeletal muscle. The issue is that skeletal muscle has a vast capacity to vasodilate during exercise [,300 mL (100 g),1 min,1], but the pumping capacity of the human heart is limited to 20,25 L min,1 in untrained subjects and ,35 L min,1 in elite endurance athletes. This means that when more than 7,10 kg of muscle is active during heavy exercise, perfusion of the contracting muscles must be limited or mean arterial pressure will fall. In the second part of the review we emphasize that there is an interplay between sympathetic vasoconstriction and metabolic vasodilation that limits blood flow to contracting muscles to maintain mean arterial pressure. Vasoconstriction in larger vessels continues while constriction in smaller vessels is blunted permitting total muscle blood flow to be limited but distributed more optimally. This interplay between sympathetic constriction and metabolic dilation during heavy whole-body exercise is likely responsible for the very high levels of oxygen extraction seen in contracting skeletal muscle. It also explains why infusing vasodilators in the contracting muscles does not increase oxygen uptake in the muscle. Finally, when ,80% of cardiac output is directed towards contracting skeletal muscle modest vasoconstriction in the active muscles can evoke marked changes in arterial pressure. [source] Formaldehyde-releasers: relationship to formaldehyde contact allergy.CONTACT DERMATITIS, Issue 1 2010Part 2. This is the second part of a review article on formaldehyde-releasers used as durable press chemical finishes (DPCF) in textiles. The early finishes contained large amounts of free formaldehyde, which led to many cases of allergic contact dermatitis to clothes in the 1950s and 1960s. Currently, most finishes are based on modified dimethylol dihydroxyethyleneurea, which releases less formaldehyde. Nevertheless, recent studies in the United States and Israel have identified patients reacting to DPCF, considered to have allergic contact reactions to clothes, either from formaldehyde released by the DPCF therein or from the DPCF per se (in patients negative to formaldehyde). However, all studies had some weaknesses in design or interpretation and in not a single case has the clinical relevance been proven. The amount of free formaldehyde in most garments will likely be below the threshold for the elicitation of dermatitis for all but the most sensitive patients. The amount of free cyclized urea DPCF in clothes is unlikely to be high enough to cause sensitization. Patch test reactions to formaldehyde-releasing DPCF will in most cases represent a reaction to formaldehyde released from the test material. [source] Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergyCONTACT DERMATITIS, Issue 1 2010Part 1. In this part of a series of review articles on formaldehyde-releasers and their relationship to formaldehyde contact allergy, formaldehyde-releasers in cosmetics are discussed. In this first part of the article, key data are presented including frequency of sensitization and of their use in cosmetics. In Europe, low frequencies of sensitization have been observed to all releasers: 2-bromo-2-nitropropane-1,3-diol 0.4,1.2%, diazolidinyl urea 0.5,1.4%, imidazolidinyl urea 0.3,1.4%, quaternium-15 0.6,1.9% (for DMDM hydantoin no recent data are available). All releasers score (far) higher prevalences in the USA; the possible explanations for this are discussed. The relevance of positive patch test reactions has been insufficiently investigated. In the USA, approximately 20% of cosmetics and personal care products (stay-on products: 17%, rinse-off products 27%) contain a formaldehyde-releaser. The use of quaternium-15 is decreasing. For Europe, there are no comparable recent data available. In the second part of the article, the patch test relationship of the releasers in cosmetics to formaldehyde contact allergy will be reviewed and it will be assessed whether products preserved with formaldehyde-releasers may contain enough free formaldehyde to pose a threat to individuals who have contact allergy to formaldehyde. [source] Elementary Many-Particle Processes in Plasma MicrofieldsCONTRIBUTIONS TO PLASMA PHYSICS, Issue 3 2006M. Yu. Abstract The effect of electric and magnetic plasma microfields on elementary many-body processes in plasmas is considered. As detected first by Inglis and Teller in 1939, the electric microfield controls several elementary processes in plasmas as transitions, line shifts and line broadening. We concentrate here on the many-particle processes ionization, recombination, and fusion and study a wide area of plasma parameters. In the first part the state of art of investigations on microfield distributions is reviewed in brief. In the second part, various types of ionization processes are discussed with respect to the influence of electric microfields. It is demonstrated that the processes of tunnel and rescattering ionization by laser fields as well as the process of electron collisional ionization may be strongly influenced by the electric microfields in the plasma. The third part is devoted to processes of microfield action on fusion processes and the effects on three-body recombination are investigated. It is shown that there are regions of plasma densities and temperatures, where the rate of nuclear fusion is accelerated by the electric microfields. This effect may be relevant for nuclear processes in stars. Further, fusion processes in ion clusters are studied. Finally we study in this section three-body recombination effects and show that an electric microfield influences the three-body electron-ion recombination via the highly excited states. In the fourth part, the distribution of the magnetic microfield is investigated for equilibrium, nonequilibrium, and non-uniform magnetized plasmas. We show that the field distribution in a neutral point of a non-relativistic ideal equilibrium plasma is similar to the Holtsmark distribution for the electrical microfield. Relaxation processes in nonequilibrium plasmas may lead to additional microfields. We show that in turbulent plasmas the broadening of radiative electron transitions in atoms and ions, without change of the principle quantum number, may be due to the Zeeman effect and may exceed Doppler and Stark broadening as well. Further it is shown that for optical radiation the effect of depolarization of a linearly polarized laser beams propagating through a magnetized plasma may be rather strong. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Green marketing philosophy: a study of Spanish firms with ecolabelsCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 1 2006Antonio Chamorro Abstract The current work attempts to highlight the importance of there being a true corporate commitment towards protecting the environment behind any green communication , i.e., that ecological awareness should be one of the values determining organizational culture. This implies that green marketing should be understood not solely as an activity, but also as a philosophy. In the first part of the article, we discuss the difficulty in measuring the environmental culture of a firm and we propose a series of indicators for this purpose. In the second part, we apply these indicators to the Spanish industrial firms that have at least one ecolabelled product, with a view to deciding whether ecolabels are used as simple sales pitch or, in contrast, there really exists a company behind them with a true environmental culture. Copyright © 2005 John Wiley & Sons, Ltd and ERP Environment. [source] Downstream from calcium signalling: mitochondria, vacuoles and pancreatic acinar cell damageACTA PHYSIOLOGICA, Issue 1 2009S. Voronina Abstract Ca2+ is one of the most ancient and ubiquitous second messengers. Highly polarized pancreatic acinar cells serve as an important cellular model for studies of Ca2+ signalling and homeostasis. Downstream effects of Ca2+ signalling have been and continue to be an important research avenue. The primary functions regulated by Ca2+ in pancreatic acinar cells , exocytotic secretion and fluid secretion , have been defined and extensively characterized in the second part of the last century. The role of cytosolic Ca2+ in cellular pathology and the related question of the interplay between Ca2+ signalling and bioenergetics are important current research lines in our and other laboratories. Recent findings in these interwoven research areas are discussed in the current review. [source] Gazing at the Hand: A Foucaultian View of the Teaching of Manipulative Skills to Introductory Chemistry Students in the United States and the Potential for Transforming Laboratory InstructionCURRICULUM INQUIRY, Issue 3 2005STEPHEN DEMEO ABSTRACT Many studies of chemistry have described the rise of the academic chemical laboratory and laboratory skills in the United States as a result of famous men, important discoveries, and international influences. What is lacking is a perspective of the manifestations of the balances of power and knowledge between teacher and student. A Foucaultian analysis of the teaching of manipulative skills to the introductory student in high school and college in the United States during the later half of the 19th and into the 20th century has provided such a perspective. The analysis focuses on the body, specifically students' hands, and how this body has been redescribed in terms of time, space, activity, and their combinations. It is argued in the first part of this article that the teaching of manipulative skills in the chemistry laboratory can be characterized by effects of differential forms of power and knowledge, such as those provided by Foucault's ideas of hierarchical observation, normalization, and the examination. Moreover, it is evident that disciplinary techniques primarily focused on the physical hands of the student have been recast to include a new cognitive-physiological space in which the teaching of manipulative skills currently takes place. In the second part of this article, the author describes his own professional development as a laboratory instructor through a series of reflective statements that are critiqued from a Foucaultian perspective. The personal narratives are presented in order to pro- vide science educators with an alternative way for their students to think about the relationship between one's manipulative skills and the quality of their data. The pedagogical approach is related to the maturation process of the chemist and contextualized in the current paradigm of laboratory practice, inquiry-based science education. [source] Stories of Schools/Teacher Stories: A Two-Part Invention on the Walls ThemeCURRICULUM INQUIRY, Issue 1 2000Cheryl J. Craig Patterned in the style of a musical invention, this work adopts Clandinin and Connelly's metaphor of a professional knowledge landscape (1995), Olson's conceptualization of the narrative authority (1993, 1995) of teacher knowledge, and my idea that teachers develop their knowledge in knowledge communities (Craig 1992, 1995a, 1995b, 1998). The first invention outlines the stories of school (Clandinin & Connelly 1996) that Riverview School and Evergreen School were given and the changes that take place over time. The second invention features beginning teacher, Benita Dalton, and her narratives of experience lived and told in the two school contexts. Relating the teacher's stories to the narrative accounts of the two campuses illustrates the extent to which context shapes teachers' practices and bounds their knowing. The work sheds much light on the subtle complexities of teachers' professional knowledge landscapes and adds to the conceptual base of a line of inquiry that focuses on the shaping effect of context on teachers' knowledge developments. An invention, loosely defined, involves the creation, through thought and/or action, of something that did not exist before. Written in the style of a musical invention, this piece is composed of two parts featuring the stories of two schools played against the evolving stories of a teacher who worked in both contexts. While the two parts of the invention both develop the walls theme, each unfolds in a different manner. The two variations which constitute the first part of the invention center on the stories of school (Clandinin & Connelly 1996) that Riverview School and Evergreen School were given and examines how these stories changed over time. The two variations that comprise the second part of the invention highlight beginning teacher, Benita Dalton, her stories of experience (Connelly & Clandinin 1990) lived and told at the two schools, and shifts that took place in her knowledge development. Connecting the fine-grained accounts of an individual with the coarse-grained accounts of schools reveals the extent to which stories of school influence teachers' practices, set the horizons of what is available for teachers to come to know, and adds to the conceptual base of a line of research that examines the how teachers' knowledge developments are influenced by context. The work begins with introductions to Benita Dalton and me, the teacher and the researcher in the study. Discussions of the research method and the theoretical framework appear next. These preliminary sketches prepare the reader for the two-part invention that follows. They lay the methodological groundwork as well as provide lenses with which to view, and a language with which to describe, contextual experiences. The next segment of the piece is Part I of the Invention comprised of Variation I: A Narrative Account of Riverview School, Variation II: A Narrative Account of Evergreen School, and a reflective coda on stories of schools. These passages bring the first part of the invention to closure. Next comes Invention II, the second movement of the piece, featuring Variation I: A Story of Benita's Experience at Riverview and Variation II: A Story of Benita's Experience at Evergreen. As with the first part of the invention, a reflective coda appears at the end of Benita's stories of experience that concludes the second part of the invention. The article ends with a grand finale, where the parallel stories developed in the invention's two parts are intentionally brought together for practical and theoretical purposes. These closing passages specifically address the principle question, the simple melody around which this two-part inquiry/invention has been constructed/composed: How does context affect teachers' knowledge developments? [source] Healing of 400 intra-alveolar root fractures.DENTAL TRAUMATOLOGY, Issue 4 2004Abstract,,, This is the second part of a retrospective study of 400 root-fractured permanent incisors. In this article, the effect of various treatment procedures is analyzed. Treatment delay, i.e. treatment later than 24 h after injury, did not change the root fracture healing pattern, healing with hard tissue between fragments (HH1), interposition of bone and/or periodontal ligament (PDL) or pulp necrosis (NEC). When initial displacement did not exceed 1 mm, optimal repositioning appeared to significantly enhance both the likelihood of pulpal healing and hard tissue repair (HH1). Significant differences in healing were found among the different splinting techniques. The lowest frequency of healing was found with cap splints and the highest with fiberglass or Kevlar® splints. The latter splinting procedure showed almost the same healing result as non-splinting. Comparison between non-splinting and splinting for non-displaced teeth was found to reveal no benefit from splinting. With respect to root fractures with displacement, too few cases were available for analysis. No beneficial effect of splinting periods greater than 4 weeks could be demonstrated. The administration of antibiotics had the paradoxical effect of promoting both HH1 and NEC. No explanation could be found. It was concluded that, optimal repositioning seems to favor healing. Furthermore, the chosen splinting method appears to be related to healing of root fractures, with a preference to pulp healing and healing fusion of fragments to a certain flexibility of the splint and possibly also non-traumatogenic splint application. Splinting for more than 4 weeks was not found to influence the healing pattern. A certain treatment delay (a few days) appears not to result in inferior healing. The role of antibiotics upon fracture healing is questionable. [source] Wildlife and Politics: CAMPFIRE in ZimbabweDEVELOPMENT AND CHANGE, Issue 3 2000Jocelyn Alexander CAMPFIRE programmes have been hailed internationally for the innovative ways in which they have sought to confront the challenges of some of Africa's most marginal regions through the promotion of local control over wildlife management. In Zimbabwe, CAMPFIRE has been cast as an antidote to the colonial legacy of technocratic and authoritarian development which had undermined people's control over their environment and criminalized their use of game. This article explores why such a potentially positive programme went so badly wrong in the case of Nkayi and Lupane districts, raising points of wider significance for comparable initiatives. Local histories and institutional politics need careful examination. The first part of the article thus investigates the historical forces which shaped attitudes to game, while the second part considers the powerful institutional and economic forces which conspired to sideline these historically formed local views. CAMPFIRE in Nkayi and Lupane was further shaped by the legacies of post-independence state violence in this region, and the failure of earlier wildlife projects. This range of factors combined to create deep distrust of CAMPFIRE, and quickly led to open confrontation. [source] Adenocarcinoma in colonic brushing cytology: High-grade dysplasia as a diagnostic pitfallDIAGNOSTIC CYTOPATHOLOGY, Issue 5 2001Gordon H. Yu M.D. Abstract Cytologic evaluation of brushing specimens obtained from the colon may be useful in the diagnosis of neoplastic and inflammatory lesions, as previous studies have reported favorable sensitivity and specificity figures for this procedure. In this study, we report our experience with 80 colonic brushings examined over a 5-yr period. Thirty cases received an atypical or malignant cytologic diagnosis. Nineteen of 20 cases diagnosed cytologically as adenocarcinoma revealed adenocarcinoma on biopsy; one case showed only adenomatous epithelium on biopsy and subsequent resection. Cases diagnosed cytologically as "atypical" or "adenomatous" showed adenocarcinoma, adenoma, and inflammatory conditions upon biopsy. Slides from 30 atypical/malignant cases were retrospectively reviewed for a number of cytomorphologic features and were correlated with the histologic diagnosis. Cases from histologically confirmed adenocarcinoma tended to show greater degrees of altered nuclear polarity, nuclear pleomorphism, membrane irregularities, and chromatin pattern alterations than those from histologically proven adenomatous or inflammatory lesions. The most likely cause of a false-positive diagnosis in this setting is sampling of an adenoma with high-grade dysplasia which fails to meet histologic criteria for adenocarcinoma (invasion of the underlying muscularis mucosae). Thus, in the second part of the study, we examined histologic sections from surgically excised adenomas to determine the frequency with which profound nuclear atypia is at least focally present, potentially resulting in a false-positive cytology diagnosis upon brushing. Slides from 51 cases were reviewed; cytologic atypia beyond that typically observed in adenomas was not observed in 43% of cases. However, profound nuclear atypia was present in 6% of cases; cytologic evaluation of a brushing specimen from these lesions may have resulted in a false-positive diagnosis of adenocarcinoma, despite the histologic diagnosis of adenoma with severe dysplasia. The remaining cases demonstrated intermediate degrees of atypia. These findings serve to quantitate the frequency with which cytohistologic discrepancies might be expected for mass lesions of the colon. Diagn. Cytopathol. 24:364,368, 2001. © 2001 Wiley-Liss, Inc. [source] Screening for dyslexia, dyspraxia and Meares-Irlen syndrome in higher educationDYSLEXIA, Issue 1 2009S. A. Nichols Abstract This study reports a comparison of screening tests for dyslexia, dyspraxia and Meares-Irlen (M-I) syndrome in a Higher Education setting, the University of Worcester. Using a sample of 74 volunteer students, we compared the current tutor-delivered battery of 15 subtests with a computerized test, the Lucid Adult Dyslexia Screening test (LADS), and both of these with data on assessment outcomes. The sensitivity of this tutor battery was higher than LADS in predicting dyslexia, dyspraxia or M-I syndrome (91% compared with 66%) and its specificity was lower (79% compared with 90%). Stepwise logistic regression on these tests was used to identify a better performing subset of tests, when combined with a change in practice for M-I syndrome screening. This syndrome itself proved to be a powerful discriminator for dyslexia and/or dyspraxia, and we therefore recommend it as the first stage in a two-stage screening process. The specificity and sensitivity of the new battery, the second part of which comprises LADS plus four of the original tutor delivered subtests, provided the best overall performance: 94% sensitivity and 92% specificity. We anticipate that the new two-part screening process would not take longer to complete. Copyright © 2008 John Wiley & Sons, Ltd. [source] From episcopal conception to monastic compilation: Hemming's Cartulary in contextEARLY MEDIEVAL EUROPE, Issue 3 2002Francesca Tinti This article examines the structure and the contents of the late eleventh century Worcester cartulary which forms the second part of London, British Library, Cotton Tiberius A. XIII. Its sections are analysed and checked against the explanatory statements on the composition of the libellus provided by Hemming in his Enucleatio. This essay then contextualizes the composition of the cartulary through an analysis of its various components. Particular attention is paid to the development of the monastic community of Worcester in the late eleventh century and the ways in which the manuscript seems to reflect their acquisition of a specific and distinctive identity. The development, therefore, of their relationship with the bishop of Worcester is especially significant. The evidence provided by the cartulary suggests that, by the time the Norman Samson succeeded Bishop Wulfstan II in 1096, the monks' attitude towards their bishop had noticeably changed from the time when Wulfstan had first suggested the cartulary's composition. [source] Simplified inelastic seismic analysis of base-isolated structures using the N2 methodEARTHQUAKE ENGINEERING AND STRUCTURAL DYNAMICS, Issue 9 2010Vojko Kilar Abstract In the paper a simplified nonlinear method has been applied to the analysis of base-isolated structures. In the first part, a three-linear idealization of the capacity curve is proposed. The initial stiffness is defined based on the first yielding point in the superstructure, whereas the secondary slope depends on the failure mechanism of the superstructure. A consequence is a much more pronounced secondary slope, which does not correspond to the presumptions used in the originally proposed N2 method. A parametric nonlinear dynamic study of single degree of freedom systems with different hardening slopes and damping has been performed for an ensemble of seven EC8 spectrum-compatible artificial accelerograms. It was concluded that, in the long-period range, the equal displacement rule could be assumed also for the proposed systems with non-zero post-yield stiffness. In the second part, the proposed idealization was used for the analysis of isolated RC frame buildings that were isolated with different (lead) rubber-bearing isolation systems. The stiffness of the isolators was selected for three different protection levels and for three different ground motion intensities, which have resulted in elastic as well as moderately and fully damaged superstructure performance levels. Three different lateral load distributions were investigated. It was observed that a triangular distribution, with an additional force at the base, works best in the majority of practical cases. It was concluded that the N2 method can, in general, provide a reasonably accurate prediction of the actual top displacement, as well as of the expected damage to the superstructure. Copyright © 2009 John Wiley & Sons, Ltd. [source] A diversity of beta diversities: straightening up a concept gone awry.ECOGRAPHY, Issue 1 2010Part 1. The term beta diversity has been used to refer to a wide variety of phenomena. Although all of these encompass some kind of compositional heterogeneity between places, many are not related to each other in any predictable way. The present two-part review aims to put the different phenomena that have been called a beta component of diversity into a common conceptual framework, and to explain what each of them measures. In this first part, the focus is on defining beta diversity. This involves deciding what diversity is and how the observed total or gamma diversity (,) is partitioned into alpha (,) and beta (,) components. Several different definitions of "beta diversity" that result from these decisions have been used in the ecological literature. True beta diversity is obtained when the total effective number of species in a dataset (true gamma diversity,) is multiplicatively partitioned into the effective number of species per compositionally distinct virtual sampling unit (true alpha diversity,d) and the effective number of such compositional units (,Md=,/,d). All true diversities quantify the effective number of types of entities. Because the other variants of "beta diversity" that have been used by ecologists quantify other phenomena, an alternative nomenclature is proposed here for the seven most popular beta components: regional-to-local diversity ratio, two-way diversity ratio, absolute effective species turnover (=regional diversity excess), Whittaker's effective species turnover, proportional effective species turnover, regional entropy excess and regional variance excess. In the second part of the review, the focus will be on how to quantify these phenomena in practice. This involves deciding how the sampling units that contribute to total diversity are selected, and whether the entity that is quantified is all of "beta diversity", a specific part of "beta diversity", the rate of change in "beta diversity" in relation to a given external factor, or something else. [source] Alcohol: No Ordinary Commodity , a summary of the second editionADDICTION, Issue 5 2010Alcohol, Public Policy Group ABSTRACT This article summarizes the contents of Alcohol: No Ordinary Commodity (2nd edn). The first part of the book describes why alcohol is not an ordinary commodity, and reviews epidemiological data that establish alcohol as a major contributor to the global burden of disease, disability and death in high-, middle- and low-income countries. This section also documents how international beer and spirits production has been consolidated recently by a small number of global corporations that are expanding their operations in Eastern Europe, Asia, Africa and Latin America. In the second part of the book, the scientific evidence for strategies and interventions that can prevent or minimize alcohol-related harm is reviewed critically in seven key areas: pricing and taxation, regulating the physical availability of alcohol, modifying the drinking context, drink-driving countermeasures, restrictions on marketing, education and persuasion strategies, and treatment and early intervention services. Finally, the book addresses the policy-making process at the local, national and international levels and provides ratings of the effectiveness of strategies and interventions from a public health perspective. Overall, the strongest, most cost-effective strategies include taxation that increases prices, restrictions on the physical availability of alcohol, drink-driving countermeasures, brief interventions with at risk drinkers and treatment of drinkers with alcohol dependence. [source] Electrochemistry of Nucleic Acids at Solid Electrodes and Its ApplicationsELECTROANALYSIS, Issue 15 2004Patricia de-los-Santos-Álvarez Abstract The knowledge of the redox chemistry of nucleic acids (NA) is of paramount importance in cancer and aging research. Charge migration through DNA is also involved in biologically relevant functions such as DNA damage and repair. In the first part of this article the main aspects of the electrochemistry of nucleic acids at solid electrodes are revised, including redox processes, photoelectroactivity and electrical conductivity. In the second part, an overview of its applications is presented. Methods for electrochemical detection of NA, NA-based biosensors for detection of nonnucleic acid molecules, studies on the nature and dynamics of interactions and structural conformations of NA, are some applications that take advantage of NA electrochemistry at solid electrodes. [source] Cover Picture: Electrophoresis 16/2008ELECTROPHORESIS, Issue 16 2008Article first published online: 13 AUG 200 Issue no. 16 is a Special Issue on "Affinity and Immunoaffinity CE and CEC" consisting of 23 papers that are arranged into five parts. The first part has 4 review articles followed by a selection of 5 papers in the second part on the application of affinity CE and CEC assembled . The third part comprises a series of papers on more specialized applications of ACE and the fourth part deals with immunoaffinity applications. Finally, the fifth part is a collection of chip-based applications. [source] Erythropoiesis and red cell function in vertebrate embryosEUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Issue 2005R. Baumann Abstract All vertebrate embryos produce a specific erythroid cell population , primitive erythrocytes , early in development. These cells are characterized by expression of the specific embryonic haemoglobins. Many aspects of primitive erythropoiesis and the physiological function of primitive red cells are still enigmatic. Nevertheless, recent years have seen intensive efforts to characterize in greater detail the molecular events underlying the initiation of erythropoiesis in vertebrate embryos. Several key genes have been identified that are necessary for primitive and the subsequent definitive erythropoiesis, which differs in several aspect from primitive erythropoiesis. This review gives in its first part a short overview dealing with comparative aspects of primitive and early definitive erythropoiesis in higher and lower vertebrates and in the second part we discuss the physiological function of primitive red cells based mainly on results from mammalian and avian embryos. [source] The Education Lending Policy of the European Investment BankEUROPEAN JOURNAL OF EDUCATION, Issue 1 2009ALBERT TUIJNMAN The purpose of this article is to present the latest Education Lending Policy (ELP) of the European Investment Bank (EIB), adopted by the Board of Governors in 2008. It is structured in two parts. The first briefly presents the EIB in general and the evolution of its education lending portfolio in particular. This sets the stage for the second part of the article, which reproduces the Bank's new ELP , only the second such formal education sector policy statement adopted by the institution to date. [source] Experimental Research and the Managerial Attitude: a tension to be resolved?EUROPEAN JOURNAL OF EDUCATION, Issue 3 2008MARTIN BENNINGHOFF This article analyses some typical consequences of a specific research policy on experimental research in biology. The policy is conducted by a national funding agency , the Swiss National Science Foundation , through a particular programme, the ,National Centres of Competence in Research' which is designed to promote both ,scientific excellence'and,managerial professionalism'. To study the possible tension between the two objectives, as a practical matter for researchers, the proposed analysis focuses on the interaction between two laboratory scientists and the administrators of a genomic platform. Access to the instruments of this platform is granted through a preliminary interview with those in charge of the platform. During that interview, researchers are required to explain why they want to use the platform services and what their expectations concerning their envisaged activities are. A tape-recorded interview is analysed in order to describe how turns at talking by the various parties, as well as the formulation of the problems encountered by a researcher, prove category-bound. The first part of the meeting (,problem exposition') is structured by the categorical device ,generalist researcher vs. specialist researcher', whilst the second part (,problem solving') is organised by the categorical device ,manager vs. user of the platform'. The ,scientific' problem becomes a ,technical' one and the choice of technique is partly based on financial reasons. The situation shows how managerial injunctions of research policy are not without practical consequences for research activities in situ. [source] Enthalpy/Entropy Compensation in the Melting of Thermotropic Nitrogen-Containing Chelating Ligands and Their Lanthanide Complexes: Successes and Failures,,EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 18 2010Aude Escande Abstract In this short overview dedicated to the thermodynamics of liquid crystalline chelating nitrogen-containing ligands and their lanthanide complexes (i.e., lanthanidomesogens), we first go through the initial successes obtained with the introduction of the concept of enthalpy/entropy compensation for rationalizing and programming melting and clearing temperatures in thermotropic mesophases. In the second part, the failures encountered during our attempts for switching from a qualitative toward a quantitative interpretation of the melting processes in polycatenar lanthanidomesogens are discussed, together with the delicate correlations established between the thermodynamic parameters of intermolecular cohesion measured in noncoordinating solvents and those operating in pure mesophases. [source] The Causal Exclusion PuzzleEUROPEAN JOURNAL OF PHILOSOPHY, Issue 1 2002David Pineda The article is divided into two parts. The first part offers a careful reconstruction and detailed discussion of the argument of causal exclusion, as well as of the implications it has for physicalism. In its second part the article examines two important objections to the causal exclusion argument: the generalization objection, which holds that the argument is unacceptable since it confers causal efficacy only to ultimate basic properties, which arguably might not exist; and Yablo's objection, according to which underlying the argument of causal exclusion there is a principle of causal parsimony which leads to strong counterintuitive results and should therefore be abandoned. The article offers grounds for rejecting both objections as well as a new diagnosis of the problem for mental causation generated by the causal exclusion argument. [source] New regionalism in five Swiss metropolitan areas: An assessment of inclusiveness, deliberation and democratic accountabilityEUROPEAN JOURNAL OF POLITICAL RESEARCH, Issue 4 2007DANIEL KÜBLER In the first, theoretical, part it draws upon the debate on old and new routes towards regionalism in order to identify four different types of metropolitan governance. It then develops two working hypotheses , an optimistic and a pessimistic one , in order to analyse the implications of various types of metropolitan governance on inclusiveness, modes of decision making and democratic accountability. In the second part, these hypotheses are tested on the basis of comparative case studies on twenty schemes of area-wide policy coordination in five Swiss metropolitan areas in the fields of water supply, public transport, social services for drug users and cultural amenities. The results suggest that ,governance' is superior to ,government' in terms of inclusiveness, that it cannot be seen as significantly linked to the fostering of deliberative decision making, and that it can present serious flaws in terms of accountability. It is noted, however, that a shift ,from government to governance' does not intrinsically imply democratic drawbacks. Contextual factors play a strong conditioning role. [source] Communicating expectancies about othersEUROPEAN JOURNAL OF SOCIAL PSYCHOLOGY, Issue 6 2006Daniël H. J. Wigboldus The linguistic expectancy bias hypothesis predicts that, in general, person impressions are shared with others via subtle differences in the level of linguistic abstraction that is used to communicate expected and unexpected information about an individual. In a two-part communication experiment, we examined this hypothesis. In the first part of the experiment communicators were asked to provide a description of an event where a good friend had behaved in an expected or unexpected way. In the second part, recipients of these stories who were blind to the conditions under which the description was generated judged whether the story target's behavior was due to dispositional or situational factors. Behaviors in expected events were judged to be more dispositional relative to behaviors in unexpected events. As predicted, the level of linguistic abstraction mediated this effect. It is concluded that person impressions may be transmitted and formed at an interpersonal level via differential language use. Copyright © 2006 John Wiley & Sons, Ltd. [source] Implicit and explicit measures of prejudice and stereotyping: do they assess the same underlying knowledge structure?EUROPEAN JOURNAL OF SOCIAL PSYCHOLOGY, Issue 6 2004Michaël Dambrun Do implicit and explicit measures of ethnic attitudes assess the same underlying knowledge structure in long term memory? This study uses both a correlational and an experimental design (N,=,133) in order to address this central question. In the first part, we suggest that self-presentational strategies can partly explain why the relation between implicit and explicit measures is inconsistent in the existing literature. More specifically, we show that when there are strong norms against prejudice, implicit and explicit measures are significantly negatively related. In the second part, an experimental manipulation of relative gratification (RG), the opposite of relative deprivation, reveals that when the level of explicit prejudice increases (RG condition), a similar effect is also observed at the implicit level. Together, these results suggest that implicit and explicit measures assess similar knowledge structure. Copyright © 2004 John Wiley & Sons, Ltd. [source] A European Constitution in a Multinational Europe or a Multinational Constitution for Europe?EUROPEAN LAW JOURNAL, Issue 3 2006Vito Breda How can we transcend our divisions without marginalising those who believe in them? This article critically analyses the theoretical bases of the Treaty Establishing a Constitution for Europe and tries to explain why its ratification is so problematic. Authors such as Habermas have argued that a new European model of social cohesion is needed, and Habermas suggests that the sense of ,community' in a democratic Europe should be founded exclusively on the acceptance of a patriotic constitution. However, this view is criticised by authors such as Weiler and MacCormick. In this article, I explain the limits of these theoretical analyses. I will argue that a European constitutional project can be more than formally legal only if two normative conditions are satisfied: it is the result of public debate and the European Constitution includes the procedures for the recognition of European national diversity. I suggest that a theory of constitutional multinationalism, similar to the one proposed by Tully, might provide an attractive model for a European social integration. The article is divided in two parts. In the first, I explain why Habermas' constitutional patriotism or MacCormick's states based Europe cannot provide a convincing theoretical model for a socially and constitutionally integrated Europe. In the second part, I will give an outline of Tully's idea of multinational democracy as a model for a European constitutional integration. [source] The Treaty of Nice: The Sharing of Power and the Institutional Balance in the European Union,A Continental PerspectiveEUROPEAN LAW JOURNAL, Issue 3 2001Xenophon A. Yataganas This paper presents an initial response to the conclusions of the Nice Summit and the new EU Treaty which emerged from it. It consists of two parts: in the first I discuss the climate in which the Intergovernmental Conference (IGC) took place and the opening positions of the Institutions, the Member States, and the applicant countries. The results achieved at Nice are set out in the second part, with special emphasis on the themes that mark a shift of power within the Community's institutional architecture; i.e. the extension of qualified-majority voting in the Council and the co-decision procedure with the European Parliament, the reweighting of votes and the composition of the Institutions with a view to an enlargement which is both imminent and unprecedented in the history of the EU. I conclude that while the results of the IGC and the new Treaty of Nice fall short of what is needed in an EU with ambitions on a continental scale, they do mark another stage in the process of European integration and the permanent evolution of its constitution. In this sense, the balance of power is likely to be different from what it has been in the past. The Franco-German axis has been severely weakened, the UK and Spain seem to be determined to play a central role, and the smaller countries are seeking to retain some influence over how the process works. New alliances are likely to emerge, particularly after enlargement, with Germany in search of a dominant position, France desperately trying to preserve the status quo, and the UK wanting to influence the direction of moves towards integration from the inside. Nice seems to mark an interim stage in this process. A new IGC has already been scheduled for 2004. There is no doubt that the post-Nice period will be one of transition towards a new distribution of power within the EU, sanctioned by a new, highly constitutional treaty. [source] High-frequency behavior of power inductor windings using an accurate multiconductor transmission line model: input impedance evaluationEUROPEAN TRANSACTIONS ON ELECTRICAL POWER, Issue 5 2008J. A. Brandão Faria Abstract This research and tutorial paper is the second part of a work dedicated to the analysis and computation of the electromagnetic behavior of inductor windings operating at high-frequency regimes,a critical issue for very fast transient overvoltage studies. The inductor winding, wound around a ferromagnetic core, containing a total number of N dielectric coated cylindrical turns, is modeled by using a multiconductor transmission line (MTL) approach (proximity effects being accounted) whose constitution and characterization was presented in a former paper. In the present work, we make use of the R, G, L, and C constitutive matrices of the structure in order to develop a modal analysis technique-based formulation aimed at the evaluation of the winding's input impedance in the frequency-domain. Results obtained show that the input impedance critically depends not only on the number of layers of the winding but also, and, more importantly, on the frequency, where resonance phenomena play a key role. Frequency-domain analysis is complemented with simulation results in the time-domain that clearly illustrate how critical and sensitive the system response can be under minute changes of the winding's excitation current. Copyright © 2007 John Wiley & Sons, Ltd. [source] Tuning and parameter variation effects in MRAS based speed estimator for sensorless vector controlled induction motor drivesEUROPEAN TRANSACTIONS ON ELECTRICAL POWER, Issue 3 2002M. Wang A frequently applied method of speed-sensorless rotor flux oriented control of induction machines relies on utilisation of model reference adaptive system (MRAS) based speed estimation, where the outputs of the reference and the adjustable model are selected as rotor flux space phasors. Accuracy of the method heavily depends on correct setting of the machine parameters and adjustment of the filter and Pl controller parameters within the estimator. The paper at first describes tuning of various parameters of the estimator, using purely experimental data. The speed estimator is operated in parallel with a commercially available rotor flux oriented induction motor drive with speed sensor and sampled stator voltages and currents are used to tune induction motor parameters, various filters and the Pl controller within the estimator. The procedure is described and illustrated using a comparison between the measured actual speed response during acceleration transients and the corresponding speed estimate obtained from the speed estimator. In the second part of the paper, speed estimation error that will take place in the base speed region due to incorrect setting and/or variation of the parameters of the machine (stator resistance, rotor resistance and magnetising inductance) within the speed estimator is assessed using experimentally recorded data. The experimental results are found to be in very good agreement with previously published theoretical results. [source] |