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Seasonal Affective Disorder (seasonal + affective_disorder)

Distribution by Scientific Domains

Medical Sciences	80%

Selected Abstracts

Lux vs. wavelength in light treatment of Seasonal Affective Disorder

ACTA PSYCHIATRICA SCANDINAVICA, Issue 3 2009
J. L. Anderson
Objective:, Published dosing guidelines for treatment of Seasonal Affective Disorder (SAD) refer to photopic lux, which is not appropriate for short-wavelength light. Short wavelengths are most potent for many non-visual responses to light. If SAD therapy were similarly mediated, standards utilizing lux risk overestimating necessary dose. We investigated antidepressant responses to light using two light-emitting diode (LED) sources, each emitting substantial short-wavelength light, but <2500 lux. Method:, A randomized, double-blind trial investigated 3-week 45 min/day out-patient treatment with blue-appearing (goLITE®) or blue-enriched white-appearing light in 18 moderately-depressed adults (12F, 49.1 ± 9.5 years). Equivalent numbers of photons within the short-wavelength range were emitted, but the white source emitted twice as many photons overall and seven-fold more lux. Results:, Depression ratings (SIGH-ADS; http://www.cet.org) decrease averaged 82% (SD = 17%) from baseline (P < 0.0001) in both white- and blue-light groups. Both sources were well tolerated. Conclusion:, Short-wavelength LED light sources may be effective in SAD treatment at fewer lux than traditional fluorescent sources. [source]

Seasonal Affective Disorder: Practice and Research.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 4 2005
A. Magnusson., T. Partonen
No abstract is available for this article. [source]

Nutritional Interventions for Treatment of Seasonal Affective Disorder

CNS: NEUROSCIENCE AND THERAPEUTICS, Issue 1 2010
Lawrence A. Palinkas
There is a need for further investigation of the effects of carbohydrate consumption as an alternative treatment for seasonal affective disorder [source]

Bright light therapy for seasonal affective disorder in Israel (latitude 32.6°N): a single case placebo-controlled study

ACTA PSYCHIATRICA SCANDINAVICA, Issue 3 2006
L. Moscovici
Introduction:, We describe a patient diagnosed as having seasonal affective disorder (SAD, winter depression), an unlikely condition in Israel (latitude 32.6°N), a country with relatively minor daylight photoperiodic changes between seasons. Method:, Case report. Results:, A 46-year-old woman with a clinical picture of depression (Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria for ,major depression with seasonal pattern') reacted positively to 3 weeks of daily bright light therapy of 10 000 lux/wide spectrum. She was asked to wear dark sunglasses during placebo sessions to accommodate an A-B-C single-case-design. The intervention resulted in an improvement of 74,80% in the Hamilton anxiety and depression scales (clinician-rated) and the Beck depression inventory, similar to results obtained in high latitude regions. The depression and anxiety levels returned close to baseline levels following 1 week of the placebo intervention. Conclusion:, Seasonal affective disorder is apparently not limited to certain latitudes. The effect of light therapy was short-lived after discontinuation of the treatment, with rapid relapse occurring in the placebo phase. [source]

A validation analysis of two self-reported HAM-D6 versions

ACTA PSYCHIATRICA SCANDINAVICA, Issue 4 2009
P. Bech
Objective:, The six items of the clinician-administrated Hamilton Depression Scale (HAM-D6) cover the core items of depressive states reflecting the antidepressive effect of medication. In this study, the two self-reported versions of the HAM-D6 have been psychometrically validated to ensure the unidimensionality of this administration form in patients with mild-to-moderate depression. Method:, The item response theory analysis of Mokken was used to test the unidimensionality of both the Interactive Voice Recording System (IVRS) version of the HAM-D6 and a paper-and-pencil self-reported version (S-HAM-D6). Patients with typical major depression and with seasonal affective disorder were included. Results:, The Mokken analysis showed that the two self-reported versions of the HAM-D6 obtained coefficients of homogeneity above 0.40, similar to the clinician-rated HAM-D6 and thus implying unidimensionality. By contrast, the full HAM-D17 versions (self-reported as well as clinician-rated) obtained coefficients of homogeneity below 0.40, implying that the HAM-D17 is a multidimensional scale. Conclusion:, The analysis show that both the IVRS version and the S-HAM-D6 version are unidimensional self-rating scales for the measurement of depressive states. [source]

Bright light therapy for seasonal affective disorder in Israel (latitude 32.6°N): a single case placebo-controlled study

CLOCK gene 3111C/T polymorphism is not associated with seasonal variations in mood and behavior in Korean college students

PSYCHIATRY AND CLINICAL NEUROSCIENCES, Issue 1 2007
JONG-WOO PAIK md
Abstract, The present study tested the potential association between the 3111C/T polymorphism of the CLOCK gene and seasonal variations in mood and behavior. A total of 297 Korean college students were genotyped for the CLOCK polymorphism and the seasonal variation was evaluated using the Seasonal Pattern Assessment Questionnaire (SPAQ). The seasonality scores were not different between CLOCK gene variants (P > 0.05). Comparison between seasonals (syndromal plus subsyndromal seasonal affective disorder according to SPAQ) and non-seasonals found no significant difference in frequencies of genotypes (P > 0.05). These findings suggest that the CLOCK polymorphism does not play a major role in susceptibility to seasonal variations in a Korean population. [source]