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Scottish Society (scottish + society)

Distribution by Scientific Domains
Medical Sciences60%
Humanities and Social Sciences40%

Selected Abstracts

Efficacy and complications of adalimumab treatment for medically-refractory Crohn's disease: analysis of nationwide experience in Scotland (2004,2008)

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 5 2009
G. T. HO
Summary Background, Adalimumab is a second generation humanized anti-tumour necrosis factor (TNF) monoclonal antibody with established efficacy in Crohn's disease (CD). Aims, To evaluate the efficacy and safety of adalimumab on a nationwide clinical setting. Methods, We used the Scottish Society of Gastroenterology network to identify and follow up the clinical outcomes of patients with CD treated with adalimumab over a 4-year period (2004,2008). Results, A total of 98 patients received adalimumab - 100.5 patient follow-up years were recorded (64.3% females; median age at diagnosis of 20.7 years; 88.8% treated with 80/40 mg induction regimen. Eighty eight (89.8%) had previous infliximab with 29 (32.9%) primary nonresponders; 32 (32.6%) were corticosteroid-dependent; 47 (47.9%) were intolerant/resistant to most immunosuppressive therapies (two or more). In all, 60% of patients were in clinical remission at 1-year follow-up, with 30% and 55% requiring dose escalation to weekly therapy at 1-and 2-year follow-up respectively. Overall, 29 (29.6%) patients developed complications with eight nonfatal serious (8.2%) adverse events and 2 (2.0%) case fatalities (sepsis following perforation and disseminated colorectal cancer, respectively). Conclusions, Adalimumab is efficacious in severe and refractory CD in the clinical setting, although there remain significant therapy- and disease-related risks of serious complications. [source]

Annual Spring Meeting of the Scottish Society of Anaesthetists in Peebles, April 2010

ANAESTHESIA, Issue 9 2010
Article first published online: 21 JUL 2010
First page of article [source]

Annual Spring Meeting of the Scottish Society of Anaesthetists in Peebles, April 2010

ANAESTHESIA, Issue 9 2010
Article first published online: 20 JUL 2010
First page of article [source]

Patriotism, Universalism and the Scottish Conventions, 1792,1794

HISTORY, Issue 295 2004
GORDON PENTLAND
Scottish radicalism in the 1790s was informed by indigenous ideologies and traditions and by the more universalist ideology associated with the American and French revolutions and with the writings of Thomas Paine. Scottish, English and Irish radicals also operated in a British context, and throughout the decade they contested the language of British patriotism with the state and loyalists who sought to represent all radicals as essentially foreign. This article investigates the radical conventions held in Edinburgh between 1792 and 1794, which culminated in the British Convention. The majority of delegates who attended were from Scottish societies, but English radicals played prominent roles in its proceedings. The British Convention sat in the context of war with revolutionary France, when patriotism was at a premium, and was broken up by the government, who tried its leaders for sedition. At the convention, delegates appealed to a British ,constitutional idiom' to justify and legitimize their actions. This language was not only flexible enough to incorporate aspects of other ideological justifications for political reform, both secular and religious, but also allowed radicals to articulate an alternative British patriotism to that espoused by loyalists. [source]

Advocates unlimited: the numerus clausus and the college of justice in Scotland

HISTORICAL RESEARCH, Issue 216 2009
John Finlay
The college of justice established in Edinburgh in 1532 provides an interesting case study of the operation of the numerus clausus rule by which a limit was placed on the number of advocates permitted to practise there. Such a rule is found in a number of European jurisdictions; however in Scotland's central court it was unusually short-lived, and lasted for less than two decades. The focus of this article is on why the rule was so briefly employed and what consequences this had for the legal profession, the court and wider Scottish society. As well as analysis of the contemporary court record, and consideration of the growth of the legal profession subsequent to the relaxation of the rule, discussion of some of the relevant considerations is informed by a debate on the same issue to be found in some inferior courts in the eighteenth century. [source]