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Selected AbstractsFibrocartilage at the entheses of the suprascapular (superior transverse scapular) ligament of man,a ligament spanning two regions of a single boneJOURNAL OF ANATOMY, Issue 5 2001B. MORIGGL The suprascapular ligament converts the suprascapular notch into a foramen separating the vessels and nerve of the same name. It connects 2 regions of the same bone and does not cross any joint, and no mechanical function has yet been attributed to it. Nevertheless, variations in its thickness and length, and its tendency to ossify, suggest that the ligament responds to changes in mechanical load. This should be reflected in the composition of the extracellular matrix. The primary purpose of the present study is to demonstrate that the suprascapular ligament has fibrocartilaginous entheses (i.e. insertion sites), even though there is no obvious change in insertional angle that directly results from joint movement. Such a change is more typical of tendons or ligaments that cross highly mobile joints. The complete ligament (including both entheses) was removed from 7 cadavers shortly after death and fixed in 90% methanol. Cryosections were immunolabelled with a panel of monoclonal antibodies against collagens (types I, II, III, VI), glycosaminoglycans (chondroitin 4 sulphate, chondroitin 6 sulphate, dermatan sulphate and keratan sulphates), proteoglycans (aggrecan and versican) and link protein. Both entheses were strongly fibrocartilaginous, and a moderately fibrocartilaginous matrix was also detected throughout the remainder of the ligament. The extracellular matrix of both entheses labelled strongly for type II collagen, aggrecan and link protein. The fibrocartilaginous character of the entheses suggests that the insertion sites of the ligament are subject to both compressive and tensile loading and are regions of stress concentration. This in turn probably reflects the complex shape of the scapula and the presence of a conspicuous indentation (the suprascapular notch) near the ligament. The loading patterns may reflect either the attachment of muscles and/or the forces transmitted to the suprascapular ligament from the neighbouring coracoclavicular ligament. [source] International Code of Area NomenclatureJOURNAL OF BIOGEOGRAPHY, Issue 7 2008Malte C. Ebach Abstract Biogeography needs a standard, coherent nomenclature. Currently, in biogeography, the same name is used for different areas of biological endemism, and one area of endemism is known by more than one name, which leads to conflict and confusion. The name ,Mediterranean', for example, may mean different things to different people , all or part of the sea, or the land in and around it. This results in ambiguity concerning the meaning of names and, more importantly, may lead to conflicts between inferences based on different aspects of a given name. We propose the International Code of Area Nomenclature (ICAN), a naming system that can be used to classify newly coined or existing names based on a standard. When fully implemented, the ICAN will improve communication among biogeographers, systematists, ecologists and conservation biologists. [source] Genetic variation and relationships among eight Indian riverine buffalo breedsMOLECULAR ECOLOGY, Issue 3 2006SATISH KUMAR Abstract Twenty-seven microsatellite loci were used to define genetic variation and relationships among eight Indian riverine buffalo breeds. The total number of alleles ranged from 166 in the Toda breed to 194 each in the Mehsana and the Murrah. Significant departures from the Hardy,Weinberg equilibrium were observed for 26 locus-breed combinations due to heterozygote deficiency. Breed differentiation was analysed by estimation of FST index (values ranging from 0.75% to 6.00%) for various breed combinations. The neighbour-joining tree constructed from chord distances, multidimensional scaling (MDS) display of FST values and Bayesian clustering approach consistently identified the Toda, Jaffarabadi, and Pandharpuri breeds as one lineage each, and the Bhadawari, Nagpuri, Surati, Mehsana and Murrah breeds as admixture. Analysis of molecular variance refuted the earlier classification of these breeds proposed on the basis of morphological and geographical parameters. The Toda buffaloes, reared by a tribe of the same name, represent an endangered breed from the Nilgiri hills in South India. Divergence time of the Toda buffaloes from the other main breeds, calculated from Nei's standard genetic distances based on genotyping data on seven breeds and 20 microsatellite loci, suggested separation of this breed approximately 1800,2700 years ago. The results of the present study will be useful for development of rational breeding and conservation strategies for Indian buffaloes. [source] Rapid model building of ,-helices in electron-density mapsACTA CRYSTALLOGRAPHICA SECTION D, Issue 3 2010Thomas C. Terwilliger A method for the identification of ,-helices in electron-density maps at low resolution followed by interpretation at moderate to high resolution is presented. Rapid identification is achieved at low resolution, where ,-helices appear as tubes of density. The positioning and direction of the ,-helices is obtained at moderate to high resolution, where the positions of side chains can be seen. The method was tested on a set of 42 experimental electron-density maps at resolutions ranging from 1.5 to 3.8,Å. An average of 63% of the ,-helical residues in these proteins were built and an average of 76% of the residues built matched helical residues in the refined models of the proteins. The overall average r.m.s.d. between main-chain atoms in the modeled ,-helices and the nearest atom with the same name in the refined models of the proteins was 1.3,Å. [source] Developing the Concept of Transparency for Use in Supply RelationshipsBRITISH JOURNAL OF MANAGEMENT, Issue 4 2004Richard Lamming Management concern surrounding the supply of goods and services from business to business, and the related attempts to understand the phenomena observed therein, appears to rest upon a broad range of incompatible perspectives, from political science (often limited to considerations of power) to the logistical (akin to manipulation of a great, benign but dynamic jigsaw puzzle). It appears that all perspectives abrade against the difficulties of exchanging information, knowledge and innovation within the relationships between buying and selling organizations and the apparent chronic systemic inefficiency that transactions often represent in this context. This article addresses these concerns, exploring the concept of transparency and the developments necessary for it to be useful in exchanging sensitive information and tacit knowledge in supply relationships. Our central concern is how the understanding of transparency and its commercial importance may change when it is expressed as a manageable element of the relationship between two organizations rather than as a general property of a broader system (e.g. a supply network, industrial sub-sector, geographical cluster) and what utility this differentiation might hold for managers. The conclusion to the article, and the implication for managers, is that transparency might indeed be created and usefully managed within supply relationships but that it would differ fundamentally in meaning from previously posited concepts, with the same name, in different contexts. [source] «Land of East Wind»: mise en forme d'une mémoire mi'gmaq,CANADIAN REVIEW OF SOCIOLOGY/REVUE CANADIENNE DE SOCIOLOGIE, Issue 2 2000P.D. Clarke This essay follows from an historical study of Heron Island (Baie des Chaleurs), and in particular, the relationship between the island and the members, past and present, of the Eel River Bar Band, from the reserve of the same name. It aims to explore elements brought to light through my observation of members of the band, and notably the processes by which the latter strive to fashion a renewed connection with Heron Island; that is, to Self and to the world. Purposefully multidisciplinary, this study focusses on the representation/construction of space and on the manner in which it acts upon its derivatives in the form of collective memory and identity. Situated at the intersection of the symbolic and material realms, this essay endeavours to shed light on the formation of the narratives that, in this instance, constitute the production (mise en scene) of a perspective space of symbolization and social objectification,a process articulated on the enunciation of goals related to socio-economic development and autonomy. At the same time, it is an attempt to account for a number of correlates to discourse, particularly practices related to social reconfiguration and the exercise of power, in a context marked by a quest for self-determination and revitalism. In short, it is an examination of a case of resistance and accommodation by a small indigenous group seeking a new world-vision. Le présent essai découle d'une étude historique portant sur l'île au Héron (Baie-des-Chaleurs) et en particulier sur les liens qui s'éta-blissent entre celle-ci et les membres, passés et présents, de la bande Eel River Bar, de la réserve du même nom. Il vise à explorer les éléments mis en relief par des observations faites dans le cadre de mes relations avec des membres de la bande, notamment les processus de l'élaboration d'un rapport renouveléà l'île au Héron, c'est-à-dire au Soi et au monde. Résolument multidisciplinaire, c'est une étude de cas qui porte sur la représentation/construction de l'espace et sur la façon dont celle-ci influe sur la mémoire collective et sur l'identité qui en dérive. Sis à l'intersection de l'univers symbolique et de l'univers matériel, cet essai cherche à mettre au jour la formation des récits qui, dans ce cas, constituent la mise en scène d'un espace perspectif de symbolisation et d'objectivation sociale, un processus articulé sur l'énonciation de desseins de développement socio-économique et d'autonomie. Parallèlement, il s'attache àéclairer les pratiques corrélatives au discursif, qui se nomment reconfiguration sociale et déploiement du pouvoir, dans un contexte de prise en main et de velléités revitalistes. En somme, il s'agit d'examiner un cas de résistance et d'accommodement de la part d'un groupe autochtone de petite taille, en mal de vision-monde. [source] Why do we need a biomechanical approach to the ocular rigidity concept?ACTA OPHTHALMOLOGICA, Issue 2009KE KOTLIAR Ocular rigidity in ophthalmology is generally assumed to be a measurable surrogate parameter related to the biomechanical properties of the whole globe. Clinical tonometry and tonography, as well as recently developed methods to assess the ocular pulse amplitude and pulsatile ocular blood flow and measurements with the ocular response analyzer are based on the concept of ocular rigidity. Clinical concepts of ocular rigidity describe a resulting effect without considerations of possible diverse morphology and material properties of the different ocular tissues. It is commonly accepted that ocular rigidity is related to the elasticity of the sclera. Many formulations are however dependent on the internal volume of the globe, intraocular pressure, corneal biomechanics and thickness of the corneoscleral shell. Sometimes this is extended to biomechanical properties of the ocular vasculature and perfusion pressure. Therefore ocular rigidity is expressed in various units and has different physical meanings but the same name is used which is confusing. Ocular biomechanics introduces parameters of elasticity and viscoelasticity of the sclera, cornea and other tissues which consider the morphology of the different tissues describing their mechanical properties such as: Young's modules of the sclera and Poisson's ratios of the cornea. When applying these rigorous statements and methods of biomechanical modeling a unified concept for ocular rigidity can be developed in order to link the limited clinical concepts, to improve them and to better understand the results of clinical measurements. [source] |