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Selected AbstractsEffect of a dose of ethanol on acute tolerance and ethanol consumption in alcohol drinker(UChB) and non-drinker (UChA) ratsADDICTION BIOLOGY, Issue 3 2002Lutske Tampier Acute tolerance that develops within minutes of ethanol exposure appears to influence the apparent acute behavioral sensitivity of laboratory animals to ethanol actions. The existence of a correlation between voluntary ethanol consumption and the speed of acquiring acute tolerance has been proposed. In the present paper we investigated the effect of an acute dose of ethanol on tolerance development and on ethanol voluntary consumption in our two selected bred strains, UChA (low ethanol drinker) and UChB (high ethanol drinker) rats. Acute tolerance developed to motor impairment induced by a dose of ethanol of 2.3 g/kg. administered intraperitoneally was evaluated by the tilting plane test. Voluntary ethanol consumption was compared in rats receiving the ethanol dose, to rats receiving a saline intraperitoneal (i.p.) injection. The results show that UChB rats receiving an intoxicating dose of ethanol develop more tolerance and they significantly increased their ethanol consumption compared to the same line that received a saline injection, while no change in acute tolerance and voluntary ethanol consumption were obtained in UChA rats. In conclusion, a possible mechanism by which UChB rats drink high amounts of ethanol appears to be the development of tolerance to the pharmacological effects of ethanol. [source] EVOLUTION UNDER RELAXED SEXUAL CONFLICT IN THE BULB MITE RHIZOGLYPHUS ROBINIEVOLUTION, Issue 9 2006Magdalena Tilszer Abstract The experimental evolution under different levels of sexual conflict have been used to demonstrate antagonistic coevolution in muscids, but among other taxa a similar approach has not been employed. Here, we describe the results of 37 generations of evolution under either experimentally enforced monogamy or polygamy in the bulb mite Rhizoglyphus robini. Three replicates were maintained for each treatment. Monogamy makes male and female interests congruent; thus selection is expected to decrease harmfulness of males to their partners. Our results were consistent with this prediction in that females from monogamous lines achieved lower fecundity when housed with males from polygamous lines. Fecundity of polygamous females was not affected by mating system under which their partners evolved, which suggests that they were more resistant to male-induced harm. As predicted by the antagonistic coevolution hypothesis, the decrease in harmfulness of monogamous males was accompanied by a decline in reproductive competitiveness. In contrast, female fecundity and embryonic viability, which were not expected to be correlated with male harmfulness, did not differ between monogamous and polygamous lines. None of the fitness components assayed differed between individuals obtained from crosses between parents from the same line and those obtained from crosses between parents from different lines within the same mating system. This indicates that inbreeding depression did not confound our results. However, interpretation of our results is complicated by the fact that both males and females from monogamous lines evolved smaller body size compared to individuals from polygamous lines. Although a decrease in reproductive performance of males from monogamous lines was still significant when body size was taken into account, we were not able to separate the effects of male body size and mating system in their influence on fecundity of their female partners. [source] On the estimation of fatigue life in notches differentiating the phases of crack initiation and propagationFATIGUE & FRACTURE OF ENGINEERING MATERIALS AND STRUCTURES, Issue 1 2010J. VÁZQUEZ ABSTRACT Over the last three decades, a variety of models have been developed in order to predict the life of components under fatigue. Some of the models are based on the definition of the fatigue process as a combination of the phases of crack initiation and crack propagation, considering component life as the sum of the duration of each phase. Other models consider only one of the phases; some consider only initiation while others only propagation, though in this case, from cracks with lengths in the order of the microstructural dimensions. This article will carry out a comparative analysis of the methods that consider life as the sum of the duration of both phases. In this same line, it proposes yet another method, which simulates crack growth according to damage theories. In analysing the behaviour of each model, this paper will describe various elements: the prediction that each of them produces regarding notched specimens submitted to testing, the advantages and inconveniences of each, and lastly, the possibilities of applying each of the models to more realistic geometries. [source] Ireland's Foreign-Owned Technology Sector: Evolving Towards Sustainability?GROWTH AND CHANGE, Issue 3 2008PATRICK COLLINS ABSTRACT For some, Ireland's pursuit of an exogenous-led development model has proved to be the cornerstone of recent economic success. Others point to recent high-profile closures and argue that foreign-owned operations are attracted to Ireland solely because of the advantageous tax breaks and lucrative grants scheme offered by the Irish government. We pay tribute to both arguments by pushing the level of enquiry beyond that of supply and backward linkages to try and gauge the actual performance of affiliates themselves. This brings some interesting facets of the Irish foreign direct investment scene to light. We highlight complexity of process, attainment of broader investment remits, and the emergence of a managerial class as integral to the ability of affiliates to adapt to and exploit organisational change. By examining 10 case studies and making use of media searches and company interviews, we highlight evidence of Ireland's largest technology transnational corporation affiliates showing positive performance advances. With these movements come, what we term, increased nodal significance of Irish operations within the global production network of their corporations. We argue against policy and theories that see these movements as linear and provide evidence of how some Irish operations have leveraged control and gained significant regional and global remits that have resulted in their growing significance, both in the corporation and in the country in which they are based. In the same line we argue that embeddedness in terms of supply linkages does not fit the Irish case and instead employ the term "network anchoring" of affiliates as they increase their nodal weighting through increased mandates. [source] A phallus for free?JOURNAL OF EVOLUTIONARY BIOLOGY, Issue 1 2003Quantitative genetics of sexual trade-offs in the snail Bulinus truncatus Abstract Resource allocation is thought to play a key role in the coexistence of different sexual morphs within hermaphroditic species. Indeed, most models assume that sexual functions are subject to a balance between reproductive advantage and energetic cost. Various types of cost (e.g. organ construction, maintenance and utilization) and levels of trade-off (physiological and genetic) may be considered. We here examine physiological and genetic costs of phallus construction and maintenance in Bulinus truncatus, a snail species in which aphallic individuals (without phallus) coexist with regular hermaphrodites. We use a quantitative genetic design involving 37 inbred lines (four populations) known to produce different proportions of aphallics, to test for the existence of genetic and nongenetic correlations between aphally and a range of life-history traits over the totality of the life cycle. Our results show that aphallic and euphallic individuals of the same line do not show consistent differences in either growth, fecundity (including offspring survival), or longevity. Furthermore, none of these traits is genetically correlated across lines with the frequency of the aphallic morph. We conclude that the cost of the construction and maintenance of the phallus must be very low in this species. Future studies should investigate the cost associated with using the phallus (i.e. male outcrossing behaviour) to explain the maintenance of high frequencies of aphallic individuals in natural populations. [source] The Idea of LiteracyJOURNAL OF PHILOSOPHY OF EDUCATION, Issue 2 2000Jim MacKenzie In this paper I show that literacy is not, as is often thought, a necessary condition for civilisation; argue that it was not, as often thought, the crucial factor in enabling the modern world to emerge from earlier civilisations; report the disadvantages of literacy as expressed by Plato's character Socrates and Milne's character Piglet, and look at the relation of literacy to reasoning and to philosophy; trace the role of the idea of literacy in the nineteenth century protocol for creating national cultures, and speculate on further developments in the same line; and then discuss its role in the modern economy and in the future. [source] A coupled model of stomatal conductance, photosynthesis and transpirationPLANT CELL & ENVIRONMENT, Issue 7 2003A. TUZET ABSTRACT A model that couples stomatal conductance, photosynthesis, leaf energy balance and transport of water through the soil,plant,atmosphere continuum is presented. Stomatal conductance in the model depends on light, temperature and intercellular CO2 concentration via photosynthesis and on leaf water potential, which in turn is a function of soil water potential, the rate of water flow through the soil and plant, and on xylem hydraulic resistance. Water transport from soil to roots is simulated through solution of Richards' equation. The model captures the observed hysteresis in diurnal variations in stomatal conductance, assimilation rate and transpiration for plant canopies. Hysteresis arises because atmospheric demand for water from the leaves typically peaks in mid-afternoon and because of uneven distribution of soil matric potentials with distance from the roots. Potentials at the root surfaces are lower than in the bulk soil, and once soil water supply starts to limit transpiration, root potentials are substantially less negative in the morning than in the afternoon. This leads to higher stomatal conductances, CO2 assimilation and transpiration in the morning compared to later in the day. Stomatal conductance is sensitive to soil and plant hydraulic properties and to root length density only after approximately 10 d of soil drying, when supply of water by the soil to the roots becomes limiting. High atmospheric demand causes transpiration rates, LE, to decline at a slightly higher soil water content, ,s, than at low atmospheric demand, but all curves of LE versus ,s fall on the same line when soil water supply limits transpiration. Stomatal conductance cannot be modelled in isolation, but must be fully coupled with models of photosynthesis/respiration and the transport of water from soil, through roots, stems and leaves to the atmosphere. [source] The compound Poisson process perturbed by a diffusion with a threshold dividend strategyAPPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY, Issue 1 2009Kam C. Yuen Abstract In this paper, we consider the compound Poisson process perturbed by a diffusion in the presence of the so-called threshold dividend strategy. Within this framework, we prove the twice continuous differentiability of the expected discounted value of all dividends until ruin. We also derive integro-differential equations for the expected discounted value of all dividends until ruin and obtain explicit expressions for the solution to the equations. Along the same line, we establish explicit expressions for the Laplace transform of the time of ruin and the Laplace transform of the aggregate dividends until ruin. In the case of exponential claims, some examples are provided. Copyright © 2008 John Wiley & Sons, Ltd. [source] Fluoride-Free Hiyama and Copper- and Amine-Free Sonogashira Coupling in Air in a Mixed Aqueous Medium by a Series of PEPPSI-Themed Precatalysts,EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 12 2009Chandrakanta Dash Abstract A new series of robust, user-friendly, and highly active PEPPSI-themed (pyridine-enhanced precatalyst preparation, stabilization and initiation) (NHC)PdX2(pyridine)-type (X = Cl, Br) precatalysts of C4,C5 saturated imidazole- (1,4) and triazole-based (5 and 6) N-heterocyclic carbenes for the Hiyama and Sonogashira couplings under amenable conditions are reported. Specifically 1,6 efficiently catalyze the fluoride-free Hiyama coupling of aryl halides with PhSi(OMe)3 and CH2=CHSi(OMe)3 in air in the presence of NaOH as a base in a mixed aqueous medium (dioxane/H2O, 2:1 v/v). Along the same lines, these 1,6 precatalysts also promote the Cu-free and amine-free Sonogashira coupling of aryl bromides and iodides with phenylacetylene in air and in a mixed aqueous medium (DMF/H2O, 3/1 v/v). The complexes 1,6 were synthesized by the direct reaction of the respective imidazolinium and triazolium halide salts with PdCl2 in pyridine in the presence of K2CO3 as a base. DFT studies on the catalytically relevant palladium(0) (NHC)Pd(pyridine) precursors 1a,6a reveal significant donation from the N-heterocyclic carbene lone pair onto the unfilled ,* orbital of the trans Pd,pyridine bond. This weakens the Pd-bound "throwaway" pyridine ligand, and its dissociation marks the initiation of the catalytic cycle.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source] Surface abundances of light elements for a large sample of early B-type stars , III.MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 2 2004An analysis of helium lines in spectra of 102 stars ABSTRACT Non-local thermodynamic equilibrium analysis of He i lines in spectra of 102 B stars is implemented in order to derive the helium abundance He/H, the microturbulent parameter Vt and the projected rotation velocity v sin i. A simultaneous determination of He/H and Vt for the stars is effected by analysing equivalent widths of the 4471- and 4922-Å lines primarily as indicators of He/H and the 4713-, 5016-, 5876- and 6678-Å lines primarily as indicators of Vt. The rotation velocities v sin i are found from profiles of the same lines. It is shown that, when Vt > 7 km s,1, the Vt(He i) values determined from He i lines are systematically overestimated as compared with the Vt(O ii, N ii) values derived from O ii and N ii lines. This discrepancy is especially appreciable for hot evolved B giants with Vt(He i) = 16,23 km s,1 and may indicate a failure of classical model atmospheres to represent the strong He i lines for these stars. Two programme stars, HR 1512 and 7651, are found to be helium-weak stars. The remaining 100 stars are divided into three groups according to their masses M. The microturbulent parameter Vt(He i) is low for all stars of group A (M= 4.1,6.9 M,) and for all stars with the relative ages t/tMS < 0.8 of group B (M= 7.0,11.2 M,). Their Vt(He i) values are within the 0 to 5 km s,1 range, as a rule; the mean value is Vt= 1.7 km s,1. Only evolved giants of group B, which are close to the termination of the main-sequence (MS) evolutionary phase (t/tMS > 0.8), show Vt(He i) up to 11 km s,1. The helium abundance He/H is correlated with the relative age t/tMS in both groups; the averaged He/H enhancement during the MS phase is 26 per cent. For group C, containing the most massive stars (M= 12.4,18.8 M,), the Vt(He i) values display a correlation with t/tMS, varying from 4 to 23 km s,1. The He/H determination for hot evolved B giants of the group with Vt(He i) > 15 km s,1 depends on a choice between the Vt(He i) and Vt(O ii, N ii) scales. The mean He/H enrichment by 67 per cent during the MS phase is found, if the abundances He/H are based on the Vt(O ii, N ii) scale; however, two evolved giants with especially high v sin i, HR 7446 and 7993, show the He/H enhancement by about a factor of 2.5. When using the same Vt scale, we found a trend of He/H with projected rotational velocities v sin i; a large dispersion for v sin i > 150 km s,1 can result from differences in masses M. A comparison with the stellar model computations with rotationally induced mixing shows that the observed helium enrichment during the MS phase can be explained by rotation with initial velocities 250,400 km s,1. The He/H distribution on M and v sin i based on the Vt(O ii, N ii) scale seems to be in better agreement with the theory than one based on the Vt(He i) scale. The mean value He/H = 0.10 derived for stars in the zero age main sequence (ZAMS) vicinity can be adopted as the typical initial helium abundance for early B stars in the solar neighbourhood. [source] Pyramiding of genes conferring resistance to Tomato yellow leaf curl virus from different wild tomato speciesPLANT BREEDING, Issue 6 2008F. Vidavski Abstract Tomato (Solanum lycopersicum) production in tropical and subtropical regions of the world is limited by the endemic presence of Tomato yellow leaf curl virus (TYLCV). Breeding programmes aimed at producing TYLCV-resistant tomato cultivars have utilized resistance sources derived from wild tomato species. So far, all reported breeding programmes have introgressed TYLCV resistance from a single wild tomato source. Here, we tested the hypothesis that pyramiding resistances from different wild tomato species might improve the degree of resistance of the domesticated tomato to TYLCV. We have crossed TYLCV-resistant lines that originated from different wild tomato progenitors, Solanum chilense, Solanum peruvianum, Solanum pimpinellifolium, and Solanum habrochaites. The various parental resistant lines and the F1 hybrids were inoculated in the greenhouse using viruliferous whiteflies. Control, non-inoculated plants of the same lines and hybrids were exposed to non-viruliferous whiteflies. Following inoculation, the plants were scored for disease symptom severity, and transplanted to the field. Resistance was assayed by comparing yield of inoculated plants to those of the control non-inoculated plants of the same variety. Results showed that the F1 hybrids between the resistant lines and the susceptible line suffered major yield reduction because of infection, but all hybrids were more resistant than the susceptible parent. All F1 hybrids resulting from a cross between two resistant parents, showed a relatively high level of resistance, which in most cases was similar to that displayed by the more resistant parent. In some cases, the hybrids displayed better levels of resistance than both parents, but the differences were not statistically significant. The F1 hybrid between a line with resistance from S. habrochaites and a line with resistance from S. peruvianum (HAB and 72-PER), exhibited the lowest yield loss and the mildest level of symptoms. Although the resistance level of this F1 hybrid was not statistically different from the level of resistance displayed by the 72-PER parent itself, it was statistically better than the level of resistance displayed by the F1 hybrids between 72-PER and any other resistant or susceptible line. [source] Artificial infestation of sorghum spikelets with eggs of Stenodiplosis sorghicola (Coquillett) (Diptera: Cecidomyiidae) by water injectionAUSTRALIAN JOURNAL OF ENTOMOLOGY, Issue 4 2001Adam T Hardy Abstract A technique for artificially infesting sorghum spikelets with eggs of sorghum midge is described and compared with natural oviposition achieved in a glasshouse cage trial. This technique was developed to facilitate antibiosis resistance related studies of midge biology, and to overcome the reduced and inconsistent oviposition achieved in sorghum lines that contain ovipositional-antixenosis resistance. Injecting an aqueous suspension of exactly two midge eggs between the glumes of individual sorghum spikelets using a micropipette produced consistent, low egg densities across five lines of varying resistance (0.8,1.2 eggs per spikelet; 50,70% infestation), while water injection of four to six eggs per spikelet in the same lines produced high and consistent egg densities (two to three eggs per spikelet; > 80% infestation). In contrast to both of the water-injection treatments, natural oviposition within the same five lines produced inconsistent egg densities, even when midge densities were adjusted to account for the variable levels of ovipositional antixenosis present in each line (one to four eggs per spikelet; 40,80% infestation). A bioassay was also conducted to determine the effect of suspending midge eggs in water on egg hatch, neonate survival and fitness. Aqueous suspensions of midge eggs stored for 4 h at room temperature produced 79% egg hatch. However, aqueous egg suspensions refrigerated at 4°C for 1,7 days reduced egg hatch (41,64%), lowered larval longevity and reduced maximum movement of neonate larvae. No eggs hatched after 14 days of refrigerated storage. [source] | ||||||||||