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Rise
Kinds of Rise Terms modified by Rise Selected AbstractsBEARING WITNESS: TOBACCO, PUBLIC HEALTH AND HISTORY THE CIGARETTE CENTURY: THE RISE, FALL AND DEADLY PERSISTENCE OF THE PRODUCT THAT DEFINED AMERICA.ADDICTION, Issue 7 20092000., Edited by A.M. Brandt MARKETING HEALTH: SMOKING AND THE DISCOURSE OF PUBLIC HEALTH IN BRITAIN First page of article [source] Reintegrative Shaming, Procedural Justice, and Recidivism: The Engagement of Offenders' Psychological Mechanisms in the Canberra RISE Drinking-and-Driving ExperimentLAW & SOCIETY REVIEW, Issue 3 2007Tom R. Tyler Advocates of restorative justice (RJ) hypothesize that the diversion of criminal cases to RJ conferences should be more effective in lowering the rate of reoffending than traditional prosecution in court processing because the conferences more effectively engage the psychological mechanisms of reintegrative shaming and procedural justice. This study uses longitudinal data from the drinking-and-driving study in the Australian Reintegrative Shaming Experiments (RISE) to evaluate the long-term impact of reintegrative shaming and procedural justice on support for the law and on later recidivism as assessed through the use of police records and by self-report. Analysis first suggests that there is no direct effect of experimental condition on later recidivism. However, it further suggests that both traditional court-based prosecution and RJ conferences increase support for the law and lower the rate of future reoffending when they engage the social psychological mechanisms of reintegrative shaming and procedural justice and thereby increase the legitimacy of the law. Hence, the results argue for the potential value of procedures such as the RJ conference but indicate that those procedures will only achieve their objectives if they are effectively designed and implemented. [source] THE RISE AND DECLINE OF THE TUTANKHAMUN-CLASS CHARIOTOXFORD JOURNAL OF ARCHAEOLOGY, Issue 2 2004BELA I. SANDOR Summary. The Tutankhamun-class chariot, the earliest high-performance machine, existed in its refined form for about five centuries. Eight complete vehicles have survived and support the argument that they surpass all monumental structures of the pharaohs in engineering sophistication. There is no evidence of chariot racing from that era, but these chariots have many technical features that imply a pedigree based on racing. Several elements hint of thoughtful invention, advanced physical modelling and experimentation, with results that sometimes drastically and favourably differ from our concepts of vehicle design. It is difficult for us to envision a substantially better chariot made with the ancient materials of construction even if we were to apply our most advanced formulas and methods. There are two major areas of chariot analysis from an engineering standpoint, and both are accessible to non-specialists. The complex suspension system of springs and shock absorbers has advantages in structural dynamics, ride quality and safety. An example of the latter is a dual-purpose anti-roll device. The chariots' wheels have aircraft-like damage tolerance, and have fundamentally more perfect spokes and joints for carrying multi-axial loads than the wooden spokes of any classic car. This paper covers the essential technical features and historical perspectives of these chariots for archaeologists. [source] RECTANGULARIZATION AND THE RISE IN LIMIT-LONGEVITY IN A SIMPLE OVERLAPPING GENERATIONS MODEL*THE MANCHESTER SCHOOL, Issue 1 2009GREGORY PONTHIERE Whereas overlapping generations (OLG) models with endogenous longevity do not distinguish between the rectangularization phenomenon and the rise in limit-longevity, these constitute two different demographic phenomena requiring a distinct modelling. This paper presents a two-period OLG model where the probability of survival from the first to the second period, as well as the maximum length of life, are endogenously determined and influenced by public policies. The issues of existence, uniqueness and stability of a steady state are studied. It is shown that the transition towards the steady state exhibits, under mild conditions, the observed succession of phases of rectangularization and derectangularization of survival curves. [source] Efficacy Beliefs in Coach,Athlete Dyads: Prospective Relationships Using Actor,Partner Interdependence ModelsAPPLIED PSYCHOLOGY, Issue 2 2010Ben Jackson The overall purpose of the study was to investigate prospective actor and partner effects (cf. Kenny, Kashy, & Cook, 2006) of interpersonal efficacy beliefs in relation to relationship commitment, satisfaction, and effort within coach,athlete dyads. Fifty youth tennis players (mean age = 15.52 years, SD = 1.45) and their coaches (mean age = 40.17 years, SD = 13.71) provided data related to their self-efficacy, other-efficacy, and relation-inferred self-efficacy (RISE) beliefs mid-way through the competitive season. Three months later, participants provided data regarding personal effort, as well as relationship commitment and satisfaction. Actor,partner interdependence model analyses revealed positive actor effects for self-efficacy in relation to effort, and for other-efficacy in relation to commitment, effort, and satisfaction. Partner effects for other-efficacy were found in relation to relationship commitment and effort. Finally, actor and partner effects were also evident for RISE beliefs; however, these relationships were moderated by the individual's role (i.e. athlete or coach), such that the direction of actor and partner effects differed for athletes and coaches. Implications for fostering effective coach,athlete relationships are discussed. Cette recherche avait pour objectif général l'étude des retombées éventuelles sur l'acteur et son partenaire (Cf.: Kenny, Kashy & Cook, 2006) des croyances en l'efficience interpersonnelle en relation avec l'implication, la satisfaction et l'effort au sein de la dyade entraîneur-athlète. Cinquante jeunes joueurs de tennis (âge moyen = 15,52; ,= 1,45) et leurs entraîneurs (âge moyen = 40,17; ,= 13,71) ont fourni des données relatives à leurs représentations concernant l'auto-efficience, l'efficience d'autrui et l'auto-efficience émanant de la relation (RISE), cela au milieu de la période des compétitions. Trois mois plus tard, les sujets ont donné des informations se rapportant à leur effort personnel, leur implication relationnelle et leur satisfaction. Les analyses relevant du modèle de l'interdépendance acteur-partenaire ont révélé des conséquences positives pour l'acteur en ce qui concerne l'auto-efficience en relation avec l'effort et l'efficience d'autrui en relation avec l'implication, l'effort et la satisfaction. Les effets du partenaire pour l'efficacité d'autrui étaient en relation avec l'effort et l'implication relationnelle. Finalement, les effets du partenaire et de l'acteur apparaissaient également pour les croyances RISE; ces relations étaient toutefois modulées par les rôles individuels (athlète ou entraîneur), de telle sorte que le sens des effets acteur-partenaire différait pour les athlètes et les entraîneurs. On réfléchit aux applications permettant d'améliorer l'efficacité des relations athlète-entraîneur. [source] THE RISE OF THE COURT ARTIST: CAVALLINI AND GIOTTO IN FOURTEENTH-CENTURY NAPLESART HISTORY, Issue 4 2008CATHLEEN A. FLECK This article explores the ways in which the Roman artist Pietro Cavallini and the Florentine artist Giotto were received in Naples and subsequently influenced Neapolitan art. Using documents and monuments, it analyses their contribution to the artistic and political image of the Neapolitan court. A number of scholars have based their assessment of the oeuvres of Cavallini and Giotto on the writings of Lorenzo Ghiberti and Giorgio Vasari, circa one hundred and two hundred and fifty years, respectively, after the artists lived. This article considers the stylistic, aesthetic, technological and political reasons for the appointment of Cavallini and Giotto to the Angevin court, and the subsequent spread of their style in Naples. As Martin Warnke has discussed in The Court Artist (first published in German in 1985), the late medieval court gave dignities to an artist that affected his reputation. The evidence of this article indicates that the court of Naples in the fourteenth century recognized each artist's individual identity and influence, thus affirming his image and thereby promoting its own. [source] Muscle Fiber Regeneration in Human Permanent Lower Motoneuron Denervation: Relevance to Safety and Effectiveness of FES-Training, Which Induces Muscle Recovery in SCI SubjectsARTIFICIAL ORGANS, Issue 3 2005Ugo Carraro Abstract:, Morphologic characteristics of the long-term denervated muscle in animals suggest that some original fibers are lost and some of those seen are the result of repeated cycles of fiber regeneration. Muscle biopsies from lower motoneuron denervated patients enrolled in the EU Project RISE show the characteristics of long-term denervation. They present a few atrophic or severely atrophic myofibers dispersed among adipocytes and connective tissue (denervated degenerated muscle, DDM). Monoclonal antibody for embryonic myosin shows that regenerative events are present from 1- to 37-years postspinal cord injury (SCI). After 2- to 10-years FES-training the muscle cryosections present mainly large round myofibers. In the FES-trained muscles the regenerative events are present, but at a lower rate than long-term denervated muscles (myofiber per mm2 of cryosection area: 0.8 ± 1.3 in FES vs. 2.3 ± 2.3 in DDM, mean ± SD, P = 0.011). In our opinion this is a sound additional evidence of effectiveness of the Kern's electrical stimulation protocol for FES of DDM. In any case, the overall results demonstrate that the FES-training is safe: at least it does not induce more myofiber damage/regeneration than denervation per se. [source] THE NEW ZEALAND PRESS ASSOCIATION 1880,2006: THE RISE AND FALL OF A CO-OPERATIVE MODEL FOR NEWS GATHERINGAUSTRALIAN ECONOMIC HISTORY REVIEW, Issue 1 2008Article first published online: 6 FEB 200, Grant Hannis co-operatives; monopoly; New Zealand; news media; transaction costs The establishment of New Zealand's press agency, the New Zealand Press Association (NZPA), as a co-operative news gathering agency in 1880 has traditionally been regarded as reflecting a pioneering spirit of newspaper unity or as being largely determined by the political situation of the time. But these explanations are insufficient. Applying economic and organisational theories of co-operatives to the history of NZPA, this paper reveals it was market conditions that led to the creation of NZPA as a co-operative news gathering service. Following profound changes in those market conditions, NZPA recently abandoned this co-operative news gathering model. [source] Biologically inspired climbing with a hexapedal robotJOURNAL OF FIELD ROBOTICS (FORMERLY JOURNAL OF ROBOTIC SYSTEMS), Issue 4-5 2008M. J. Spenko This paper presents an integrated, systems-level view of several novel design and control features associated with the biologically inspired, hexapedal, RiSE (Robots in Scansorial Environments) robot. RiSE is the first legged machine capable of locomotion on both the ground and a variety of vertical building surfaces including brick, stucco, and crushed stone at speeds up to 4 cm/s, quietly and without the use of suction, magnets, or adhesives. It achieves these capabilities through a combination of bioinspired and traditional design methods. This paper describes the design process and specifically addresses body morphology, hierarchical compliance in the legs and feet, and sensing and control systems that enable robust and reliable climbing on difficult surfaces. Experimental results illustrate the effects of various behaviors on climbing performance and demonstrate the robot's ability to climb reliably for long distances. © 2008 Wiley Periodicals, Inc. [source] Agrifood Sector Liberalisation and the Rise of Supermarkets in Former State-controlled Economies: A Comparative OverviewDEVELOPMENT POLICY REVIEW, Issue 5 2004Thomas Reardon Former state-controlled economies (FSCEs) have become the most important destination of global retail chain investments. These economies, which spread from North Africa, across Central and Eastern Europe, to East Asia, include more than one and a half billion consumers and a large share of the world's agricultural area and poor farmers. They have undergone an often radical transformation of their agrifood system over the past decade. The take-off of supermarkets in FSCEs started seriously in the mid-late 1990s, and is now moving fast. This article compares FSCE experience in the supermarket revolution and considers its implications for policy-makers and rural development practitioners. [source] Impact of the Rapid Rise of Supermarkets on Dairy Products Systems in ArgentinaDEVELOPMENT POLICY REVIEW, Issue 4 2002Graciela E. Gutman The reconfiguration and consolidation of food retailing in Argentina during the 1990s profoundly changed the marketing system for food and agricultural products. The new commercial requirements and ,rules of the game' imposed by supermarkets on their suppliers have caused a substantial restructuring of supply chains , a process in which some suppliers fail. This article describes the changes in the past decade in the Argentine retail sector, and then focuses on the effects of those changes (and related changes in processing) on milk products supply chains. Its conclusions focus on the challenges specific to small farms and firms in the face of this transformation. [source] Colonization of nascent, deep-sea hydrothermal vents by a novel Archaeal and Nanoarchaeal assemblageENVIRONMENTAL MICROBIOLOGY, Issue 1 2006Elizabeth A. McCliment Summary Active deep-sea hydrothermal vents are areas of intense mixing and severe thermal and chemical gradients, fostering a biotope rich in novel hyperthermophilic microorganisms and metabolic pathways. The goal of this study was to identify the earliest archaeal colonizers of nascent hydrothermal chimneys, organisms that may be previously uncharacterized as they are quickly replaced by a more stable climax community. During expeditions in 2001 and 2002 to the hydrothermal vents of the East Pacific Rise (EPR) (9°50,N, 104°17,W), we removed actively venting chimneys and in their place deployed mineral chambers and sampling units that promoted the growth of new, natural hydrothermal chimneys and allowed their collection within hours of formation. These samples were compared with those collected from established hydrothermal chimneys from EPR and Guaymas Basin vent sites. Using molecular and phylogenetic analysis of the 16S rDNA, we show here that at high temperatures, early colonization of a natural chimney is dominated by members of the archaeal genus Ignicoccus and its symbiont, Nanoarchaeum. We have identified 19 unique sequences closely related to the nanoarchaeal group, and five archaeal sequences that group closely with Ignicoccus. These organisms were found to colonize a natural, high temperature protochimney and vent-like mineral assemblages deployed over high temperature outflows within 92 h. When compared phylogenetically, several of these colonizing organisms form a unique clade independent of those found in mature chimneys and low-temperature mineral chamber samples. As a model ecosystem, the identification of pioneering consortia in deep-sea hydrothermal vents may help advance the understanding of how early microbial life forms gained a foothold in hydrothermal systems on early Earth and potentially on other planetary bodies. [source] Diversity of functional genes of methanogens, methanotrophs and sulfate reducers in deep-sea hydrothermal environmentsENVIRONMENTAL MICROBIOLOGY, Issue 1 2005Olivier Nercessian Summary To contribute to the identification of methanogens, methanotrophs and sulfate-reducing bacteria (SRB) in microbial communities from the 13°N (East Pacific Rise) and Rainbow (Mid-Atlantic Ridge) hydrothermal vent fields, we investigated the diversity of mcrA, pmoA and dsrAB genes sequences. Clone libraries were obtained using DNA isolated from fragments of diffuse vents, sediment and in situ samplers. The clones were categorized by restriction fragment length polymorphism, and representatives of each group were sequenced. Sequences were related to that of hyperthermophilic (order Methanopyrales and family Methanocaldococcaceae), thermophilic and mesophilic (family Methanococcaceae) methanogens, thermophilic (proposed genus ,Methylothermus') and mesophilic type I methanotrophs, and hyperthermophilic (order Archaeoglobales), thermophilic (order Thermodesulfobacteriales) and mesophilic (family Desulfobulbaceae) SRB. Several of the obtained sequences were distantly related to the genes of cultivated organisms, providing evidence of the existence of novel lineages in the three functional groups. This study provides for the first time an insight into the diversity of several functional genes of deep-sea hydrothermal system microorganisms. [source] Uncultured Archaea in a hydrothermal microbial assemblage: phylogenetic diversity and characterization of a genome fragment from a euryarchaeoteFEMS MICROBIOLOGY ECOLOGY, Issue 3 2006Hélène Moussard Abstract The polychaete Alvinella pompejana lives in organic tubes on the walls of active hydrothermal chimneys along the East Pacific Rise. To examine the diversity of the archaeal community associated with the polychaete tubes, we constructed libraries by direct PCR amplification and cloning of 16S rRNA genes. Almost half of the sequences of the 16S rRNA gene libraries clustered with uncultured archaeal groups. In an effort to access genomic information from uncultured archaeal members we further constructed a fosmid library from the same DNA source. One of the clones, Alv-FOS5, was sequenced completely. Its sequence analysis revealed an incomplete rRNA operon and 32 predicted ORFs. Seventeen of these ORFs have been assigned putative functions, including transcription and translation, cellular processes and signalling, transport systems and metabolic pathways. Phylogenetic analyses of the 16S rRNA gene suggested that Alv-FOS5 formed a new lineage related to members of Deep-Sea Hydrothermal Vent Euryarchaeota group II. Phylogenetic analyses of predicted proteins revealed the existence of likely cases of horizontal gene transfer, both between Crenarchaeota and Euryarchaeota and between Archaea and Bacteria. This study is the first step in using genomics to reveal the physiology of an as yet uncultured group of archaea from deep-sea hydrothermal vents. [source] Microbial diversity of a sulphide spire located in the Edmond deep-sea hydrothermal vent field on the Central Indian RidgeGEOBIOLOGY, Issue 2 2003Joost Hoek ABSTRACT A culture-independent molecular phylogenetic survey was carried out for a bacterial and archaeal community of a mineralized crust coating a sulphide spire, which was collected from the Edmond vent field (23° S, 69° E, 3300 m depth) on the Central Indian Ridge. Small-subunit rRNA genes (16S rDNA) were amplified from environmental DNA by PCR utilizing Bacteria-specific, and Archaea-specific 16S rDNA primers. PCR products were cloned and 26 bacterial and nine archaeal unique sequence types (phylotypes) were identified from 150 clones analysed by restriction fragment length polymorphism, representing eight and four distinct lineages, respectively. The majority (>90%) of the bacterial phylotypes group with the ,-Proteobacteria and confirms the global prevalence of ,-Proteobacteria in deep-sea hydrothermal environments. Among the ,-Proteobacteria, >40% of the phylotypes were closely related to the recently isolated deep-sea vent thermophilic chemolithoautotrophic sulphur-reducer, Nautilia lithotrophica. A single bacterial sequence was nearly identical (99% similarity) to the thermophilic hydrogen-oxidizing Hydrogenobacter thermolithotrophum, and is the first report of Hydrogenobacter at deep-sea hydrothermal vents. A majority (97%) of the archaeal phylotypes grouped with the ,Deep-sea Hydrothermal Vent Euryarchaeotal Group', a phylogenetic lineage of uncultured Archaea that have only been reported from other deep-sea hydrothermal vents on the Mid-Atlantic Ridge, East Pacific Rise, Juan de Fuca Ridge, Isu,Ogasawara Arc, Okinawa Trough and the Manus Basin. A single sequence was closely related to the hyperthermophilic sulphur-reducing Thermococcales frequently found in diverse deep-sea vent environments. Scanning electron micrographs of the mineralized crust reveal abundant filamentous, rod and coccoidal forms encased in sulphur and sulphide mineral precipitate, suggesting that the thermophilic chemolithoautorophs and sulphide-producing heterotrophs may influence the architecture and sulphur cycling of the sulphide spire. [source] Br/Cl signature of hydrothermal fluids: liquid,vapour fractionation of bromine revisitedGEOFLUIDS (ELECTRONIC), Issue 2 2006A. LIEBSCHER Abstract Br/Cl ratios of hydrothermal fluids are widely used as geochemical tracers in marine hydrothermal systems to prove fluid phase separation processes. However, previous results of the liquid,vapour fractionation of bromine are ambiguous. Here we report new experimental results of the liquid,vapour fractionation of bromine in the system H2O,NaCl,NaBr at 380,450°C and 22.9,41.7 MPa. Our data indicate that bromine is generally more enriched than chlorine in the liquid phase. Calculated exchange coefficients KD(Br-Cl)liquid-vapour for the reaction Brvapour + Clliquid = Brliquid + Clvapour are between 0.94 ± 0.08 and 1.66 ± 0.14 within the investigated P,T range. They correlate positively with DClliquid-vapour and suggest increasing bromine,chlorine fractionation with increasing opening of the liquid,vapour solvus, i.e. increasing distance to the critical curve in the H2O,NaCl system. An empirical fit of the form KD(Br-Cl)liquid-vapour = a*ln[b*(DClliquid-vapour,1) + e1/a] yields a = 0.349 and b = 1.697. Based on this empirical fit and the well-constrained phase relations in the H2O,NaCl system we calculated the effect of fluid phase separation on the Br/Cl signature of a hydrothermal fluid with initial seawater composition for closed and open adiabatic ascents along the 4.5 and 4.8 J g,1 K,1 isentropes. The calculations indicate that fluid phase separation can significantly alter the Br/Cl ratio in hydrothermal fluids. The predicted Br/Cl evolutions are in accord with the Br/Cl signatures in low-salinity vent fluids from the 9 to 10°N East Pacific Rise. [source] Hailing with an Invisible Hand: A ,Cosy' Political Dispute amid the Rise of Neoliberal Politics in Modern IrelandGOVERNMENT AND OPPOSITION, Issue 4 2002George Taylor First page of article [source] E. coli Not on Rise in CanadaGROUND WATER MONITORING & REMEDIATION, Issue 3 2000Article first published online: 22 FEB 200 No abstract is available for this article. [source] The E-economy and the Rise of Technocapitalism: Networks, Firms, and TransportationGROWTH AND CHANGE, Issue 4 2003Luis Suarez-Villa ABSTRACT The e-economy is part of a larger phenomenon, technocapitalism, that is transforming business organizations and the ways in which they transact, produce, and ship their goods. Technocapitalism is an evolution of market capitalism that is rooted in technological innovation and supported by such intangibles as creativity and knowledge. This paper considers first the main characteristics of networks that support the e-economy and its source phenomenon, the emergence of technocapitalism. Networks are thought to be the main vehicle through which the e-economy spreads, and they have major effects on the organization of business firms. The culture of technocapitalism, with its emphasis on continuous innovation and rapid adjustment, is largely behind the rising importance of networks. A second section then considers the deconstruction of business firms and its relation to networks, the e-economy, and the rise of technocapitalism. A historical perspective is provided to show the contrast with previous eras. The deconstruction of business organizations involves a major transformation of the norms and ways in which firms are run and structured. Finally, the likely implications for transportation and shipping of the rise of the e-economy, its networks, and the deconstruction of firms are discussed. The logistics, pricing, and infrastructure of shipping are likely to be substantially affected by the spread of the e-economy, its networks, and the deconstruction of firms. [source] Money and the Rise of the Modern Papacy: Financing the Vatican, 1850,1950 By John F. PollardHISTORY, Issue 303 2006NICK CARTER No abstract is available for this article. [source] Joseph Kinmont Hart and Vanderbilt University: Academic Freedom and the Rise and Fall of a Department of Education, 1930,1934HISTORY OF EDUCATION QUARTERLY, Issue 4 2003Deron R. Boyles No one can follow the history of academic freedom, without wondering at the fact that any society, interested in the immediate goals of solidarity and self-preservation, should possess the vision to subsidize free criticism and inquiry, and without feeling that the academic freedom we still possess is one of the remarkable achievements of man. At the same time,one cannot but be disheartened by the cowardice and self-deception that frail men use who want to be both safe and free.1 [source] An Odd Thing Happened on the Way to Balancing: East Asian States' Reactions to China's RiseINTERNATIONAL STUDIES REVIEW, Issue 3 2010Steve Chan Are East Asian states reacting to China's rise according to balance-of-power expectations? This review discusses the pertinent debate and presents overtime data germane to this question. It raises several issues of theoretical argumentation and historical purview pertaining to this debate, and concludes that the conduct of China's neighbors thus far is anomalous from the traditional balance-of-power perspective. [source] The Global Implications of China's RiseINTERNATIONAL STUDIES REVIEW, Issue 4 2008Scott L. Kastner First page of article [source] The Boys from Bothaville, or the Rise and Fall of King Maize: A South African StoryJOURNAL OF AGRARIAN CHANGE, Issue 4 2004HENRY BERNSTEIN This paper tells the story, for the first time, of a maverick maize farmers' association in South Africa during the period of apartheid. NAMPO (National Maize Producers' Organization), that grew out of SAMPI (South African Maize Producers' Institute), ultimately achieved a unique, if short-lived, breach in the normal operations of ,organized agriculture': a set of relations and practices that bound together white farmers, the National Party and the state. The paper provides an account of SAMPI/NAMPO's project of ,King Maize' and an explanation of its fall after a brief period of victory from 1981 to 1985. This explanation draws on broader patterns of agrarian change in contemporary capitalism combined with the fracturing of the original agrarian bloc of apartheid in the 1980s, marking the end of a ,second moment' of South Africa's version of a Prussian path of capitalist development. [source] SOUTH AFRICA: Bad Debts are on the RiseAFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 2 2009Article first published online: 7 APR 200 No abstract is available for this article. [source] Pain and Anatomical Locations of Radiofrequency Ablation as Predictors of Esophageal Temperature Rise During Pulmonary Vein IsolationJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 1 2008ARASH ARYANA M.D. Introduction: Esophageal temperature rise (ETR) during ablation inside left atrium has been reported as a marker for esophageal thermal injury. We sought to investigate the possible relationships between chest pain and ETR during radiofrequency (RF) ablation, and ETR and locations of RF application, in patients undergoing pulmonary vein (PV) isolation under moderate sedation. Methods and Results: We analyzed anatomical locations of each RF application and its association with esophageal temperature and presence/absence of pain. Data from 40 consecutive patients (mean age: 56 ± 10 years) were analyzed. There were a total of 4,071 RF applications resulting in 291 episodes of pain (7.1%) and 223 ETRs (5.5%). Thirty-five patients (87.5%) experienced at least one pain episode and 32 (80.0%) had at least one ETR. While 77.4% of posterior wall applications that caused pain also corresponded to an ETR (P < 0.0001), only 0.8% of pain-free posterior wall applications were associated with ETRs (P < 0.0001). The sensitivity and specificity of pain during ablation for ETR were 94% and 98%, respectively. No ETRs were observed during anterior wall applications. ETRs occurred more frequently during ablation on the left (86.1%) versus the right (13.9%), and in inferior (70.4%) versus superior (29.6%) segments. Conclusion: In patients undergoing PV isolation, ETR was encountered when ablating in the posterior left atrium with the distribution left > right and inferior > superior. Pain during ablation was associated with ETR, and lack of pain was strongly associated with absence of ETR. Pain during RF ablation may thus serve as a predictor of esophageal heating and potential injury. [source] Uncertainty and the Rise of the Work-Family DilemmaJOURNAL OF MARRIAGE AND FAMILY, Issue 1 2001Mark Evan Edwards Existing research argues that women's wages, consumerism, and changing attitudes dismantled the male bread-winner system. Families' economic need is dismissed with the suggestion that mothers' rhetoric of "need" was a smoke screen to defend against social stigma for working mothers. Drawing on biennial data from 1965 to 1987, I suggest that consumptive certainty of the 1950s and 1960s gave way to economic uncertainty in the 1970s and beyond. Economic uncertainty provided impetus, legitimacy, and justification for young families to adopt new work-family arrangements. Hence, economic uncertainty is conceptualized as a real circumstance that substantiates families' reasonable perceptions of need. [source] Palaeoproterozoic high-pressure granulite overprint of the Archean continental crust: evidence for homogeneous crustal thickening (Man Rise, Ivory Coast)JOURNAL OF METAMORPHIC GEOLOGY, Issue 1 2010P. PITRA Abstract The character of mountain building processes in Palaeoproterozoic times is subject to much debate. Based on the discovery of high-pressure granulites in the Man Rise (Côte d'Ivoire), several authors have argued that Eburnean (Palaeoproterozoic) reworking of the Archean basement was achieved by modern-style thrust-dominated tectonics. A mafic granulite of the Kouibli area (Archean part of the Man Rise, western Ivory Coast) displays a primary assemblage (M1) containing garnet, diopsidic clinopyroxene, red-brown pargasitic amphibole, plagioclase (andesine), rutile, ilmenite and quartz. This assemblage is associated with a subvertical regional foliation. Symplectites that developed at the expense of the M1 assemblage contain orthopyroxene, clinopyroxene, plagioclase (bytownite), green pargasitic amphibole, ilmenite and magnetite (M2). Multiequilibrium thermobarometric calculations and P,T pseudosections calculated with thermocalc suggest granulite facies conditions of , 13 kbar, 850 °C and <7 kbar, 700,800 °C for M1 and M2, respectively. In agreement with the qualitative information obtained from reaction textures and chemical zoning of minerals, this suggests an evolution dominated by decompression accompanied by moderate cooling. A Sm,Nd garnet , whole-rock age of 2.03 Ga determined on this sample indicates that this evolution occurred during the Palaeoproterozoic. It is argued that from the geodynamic point of view the observed features are best explained by homogeneous thickening of the margin of the Archean craton, re-heated and softened due to the accretion of hot, juvenile Palaeoproterozoic crust, as well as coeval intrusion of juvenile magmas. Crustal shortening was mainly accommodated by transpressive shear zones and by lateral crustal spreading rather than large-scale thrust systems. [source] Role of Protein Kinases in the Prolactin-Induced Intracellular Calcium Rise in Chinese Hamster Ovary Cells Expressing the Prolactin ReceptorJOURNAL OF NEUROENDOCRINOLOGY, Issue 9 2000B. Sorin Abstract There is still only limited understanding of the early steps of prolactin signal transduction in target cells. It has been shown that prolactin actions are associated with cell protein phosphorylation, Ca2+ increases, and so on. However, the link between the activation of kinases and calcium influx or intracellular Ca2+ mobilization has not yet been clearly established. Chinese hamster ovary (CHO) cells, stably transfected with the long form of rabbit mammary gland prolactin receptor (PRL-R) cDNA were used for PRL-R signal transduction studies. Spectrofluorimetric techniques were used to measure intracellular calcium ([Ca2+]i) in cell populations with Indo1 as a calcium fluorescent probe. We demonstrate that, although protein kinase C activation (PMA or DiC8) caused a calcium influx in CHO cells, prolactin-induced PKC activation was not responsible for the early effect of prolactin on [Ca2+]i. Activation of protein kinase A (PKA) or protein kinase G did not modify [Ca2+]i and inhibition of PKA pathway did not affect the prolactin response. In the same way, phosphatidylinositol-3 kinaseinhibition had no effect on the prolactin-induced Ca2+ increase. On the other hand, tyrosine kinase inhibitors (herbimycin A, lavendustin A, and genistein) completely blocked the effect of prolactin on [Ca2+]i (influx and release). W7, a calmodulin-antagonist, and a specific inhibitor of calmodulin kinases (KN-62), only blocked prolactin-induced Ca2+ influx but had no significant effect on Ca2+ release. Using pharmacological agents, we present new data concerning the involvement of protein phosphorylations in the early effects of prolactin on ionic channels in CHO cells expressing the long form of PRL-R. Our results suggest that, at least in the very early steps of prolactin signal transduction, serine-threonine phosphorylation does not participate in the prolactin-induced calcium increase. On the other hand, tyrosine phosphorylation is a crucial, very early step, since it controls K+ channel activation, calcium influx, and intracellular calcium mobilization. Calmodulin acts later, since its inhibition only blocks the prolactin-induced Ca2+ influx. [source] Religious Ethics, History, and the Rise of Modern Moral Philosophy: Focus IntroductionJOURNAL OF RELIGIOUS ETHICS, Issue 2 2000Jennifer A. Herdt In this introduction to a cluster of three articles on eighteenth-century ethics written by Mark Larrimore, John Bowlin, and Mark Cladis, the author maintains that although the broad narrative tracing the emergence of a religiously neutral or naturalistic moral language in the eighteenth century is a familiar one, many central questions concerning this development remain unanswered and require further historical study. Against those who contend that historical study is antecedent to, but not part of, the proper substance of religious ethics, the author argues that historical and normative studies are interdependent, each helping to define the questions central to the other. The introduction concludes with an overview of the three articles and suggests ways in which religious ethicists can, in the future, make a distinctive contribution to the history of ethics. [source] | |||||||||||||||||||||||||||||||||||||