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Research Contexts (research + context)
Selected AbstractsRESEARCH VULNERABILITY: AN ILLUSTRATIVE CASE STUDY FROM THE SOUTH AFRICAN MINING INDUSTRYDEVELOPING WORLD BIOETHICS, Issue 3 2007LYN HORN ABSTRACT The concept of ,vulnerability' is well established within the realm of research ethics and most ethical guidelines include a section on ,vulnerable populations'. However, the term ,vulnerability', used within a human research context, has received a lot of negative publicity recently and has been described as being simultaneously ,too broad' and ,too narrow'.1 The aim of the paper is to explore the concept of research vulnerability by using a detailed case study , that of mineworkers in post-apartheid South Africa. In particular, the usefulness of Kipnis's taxonomy of research vulnerability will be examined.2 In recent years the volume of clinical research on human subjects in South Africa has increased significantly. The HIV and TB pandemics have contributed to this increase. These epidemics have impacted negatively on the mining industry; and mining companies have become increasingly interested in research initiatives that address these problems. This case study explores the potential research vulnerability of mineworkers in the context of the South African mining industry and examines measures that can reduce this vulnerability. [source] DECOLONIZING THE PRODUCTION OF GEOGRAPHICAL KNOWLEDGES?GEOGRAFISKA ANNALER SERIES B: HUMAN GEOGRAPHY, Issue 3 2006REFLECTIONS ON RESEARCH WITH INDIGENOUS MUSICIANS ABSTRACT. This paper contributes to debates on decolonizing geography, by reflecting on the ethical and political considerations involved in research on indigenous music in Australia. The research collaboration involved two non-indigenous researchers,an academic geographer and a music educator,engaging with indigenous music and musicians in a number of ways. The paper reflects on these engagements, and draws attention to a series of key binaries and boundaries that were highlighted and unsettled: ,outsider/insider'; ,traditional/contemporary'; ,authenticity/inauthenticity'. It also discusses the politics of publishing and draws attention to the ways in which the objects of our work,in this case a book,influence decisions about representation, subject matter, and interpretations of speaking positions. Rather than seeking validation for attempts to ,speak for' or ,speak to' indigenous musical perspectives, contemporary Aboriginality was understood as a field of intersubjective relations where multiple voices, representations and interventions are made. I discuss some ways in which the authors sought to situate their own musical, and geographical, knowledges in this problematic, and inherently political, research context. [source] Financial performance and the long-term link with HR practices, work climate and job stressHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 4 2005Marc van Veldhoven Using data front a large financial services organisation in the Netherlands, this article reports a longitudinal study at the business unit level. The study addresses the question of which longitudinal relations exist between survey data on perceived HR practices, work climate and job stress on the one hand, and prospective and retrospective financial performance on the other. Data from 223 business units were available for this study. Eight scales were selected from an employee survey answered by 18,142 respondents. These were aggregated to mean scores at the business unit level. Financial performance is operationalised by a yearly profits-to-costs ratio. Correcting for employee and business unit characteristics, the eight survey scales predict 22 per cent of the variance in business unit financial performance in the year after the survey.,Co-operation between departments' appears to be the most important predictor. Equally strong evidence was friund for a reverse causation sequence: business unit financial performance in the year before the survey was a significant predictor for four out of eight survey scales, especially for ,co-operation between departments' and ,job security'. The results underline the importance of studying variance in HR and performance variables within large organisatiuns, and the possibilities of using employee surveys in this research context. Limitations and implications of the findings are discussed. [source] High-sensitivity analysis of specific peptides in complex samples by selected MS/MS ion monitoring and linear ion trap mass spectrometry: Application to biological studiesJOURNAL OF MASS SPECTROMETRY (INCORP BIOLOGICAL MASS SPECTROMETRY), Issue 11 2007Inmaculada Jorge Abstract Mass spectrometry (MS) is a technique of paramount importance in Proteomics, and developments in this field have been possible owing to novel MS instrumentation, experimental strategies, and bioinformatics tools. Today it is possible to identify and determine relative expression levels of thousands of proteins in a biological system by MS analysis of peptides produced by proteolytic digestion. In some situations, however, the precise characterization of a particular peptide species in a very complex peptide mixture is needed. While single-fragment ion-based scanning modes such as selected ion reaction monitoring (SIRM) or consecutive reaction monitoring (CRM) may be highly sensitive, they do not produce MS/MS information and their actual specificity must be determined in advance, a prerequisite that is not usually met in a basic research context. In such cases, the MS detector may be programmed to perform continuous MS/MS spectra on the peptide ion of interest in order to obtain structural information. This selected MS/MS ion monitoring (SMIM) mode has a number of advantages that are fully exploited by MS detectors that, like the linear ion trap, are characterized by high scanning speeds. In this work, we show some applications of this technique in the context of biological studies. These results were obtained by selecting an appropriate combination of scans according to the purpose of each one of these research scenarios. They include highly specific identification of proteins present in low amounts, characterization and relative quantification of post-translational modifications such as phosphorylation and S -nitrosylation and species-specific peptide identification. Copyright © 2007 John Wiley & Sons, Ltd. [source] Recommendations on Use of Biomarkers in Alcoholism Treatment TrialsALCOHOLISM, Issue 10 2003John P. Allen Background: Biochemical markers of heavy drinking are playing increasingly prominent roles in alcohol treatment efficacy studies, especially in those designed to evaluate medications. Among these roles are serving as inclusion or exclusion criteria for research participants, corroboration of self-report of drinking status, assessment of the safety of the agent being evaluated, and determination of treatment outcome. Methods: Recent alcohol medication development trials that included biomarker information were reviewed and critiqued from the perspectives of how biomarker measures were used and how findings on them were reported. Results: Although generally the application of biomarkers as inclusion criteria is not recommended, they may aid in exclusion of potential subjects (e.g., elevated liver function measures in trials of agents that could result in liver damage). Biomarkers are most commonly used as indicators of outcome, usually serving as secondary outcome variables. The relationship of outcome findings on biomarker and self-report measures is positive, but only moderate. As used to date, biomarkers of drinking tend to be less sensitive than well-standardized and properly administered self-report measures. Nevertheless, they do provide a useful, unique source of information on drinking status. Conclusions: The contribution of biomarkers to alcoholism clinical research would be enhanced if certain design strategies were incorporated into their application and if critical information were included in the research publication. This article offers a series of recommendations to improve on their use in a research context. [source] Guidelines for mechanical lung function measurements in psychophysiologyPSYCHOPHYSIOLOGY, Issue 5 2002Thomas Ritz Studies in psychophysiology and behavioral medicine have uncovered associations among psychological processes, behavior, and lung function. However, methodological issues specific to the measurement of mechanical lung function have rarely been discussed. This report presents an overview of the physiology, techniques, and experimental methods of mechanical lung function measurements relevant to this research context. Techniques to measure lung volumes, airflow, airway resistance, respiratory resistance, and airflow perception are introduced and discussed. Confounding factors such as ventilation, medication, environmental factors, physical activity, and instructional and experimenter effects are outlined, and issues specific to children and clinical groups are discussed. Recommendations are presented to increase the degree of standardization in the research application and publication of mechanical lung function measurements in psychophysiology. [source] Examination of attitudes towards teaching online courses based on theory of reasoned action of university faculty in TaiwanBRITISH JOURNAL OF EDUCATIONAL TECHNOLOGY, Issue 5 2006Tzy-Ling Chen This study examined attitudes of university faculty specialising in the field of human resource (HR) in Taiwan towards participation in the teaching of online courses using the theory of reasoned action (TRA). The population targeted for investigation consisted of the full-time university faculty in the HR field in Taiwan regardless of their experience in the teaching online courses of any kind. Survey development included a detailed literature review to identify beliefs that guided measurement construction and followed the guidelines recommended by Ajzen and Fishbein (1980) to ensure construct validity. Data were collected on TRA constructs and demographic variables using the questionnaire mailed to 278 faculty members targeted for the study. A 42% (n = 116) response rate was achieved after one round of the follow-up through emailing. The significant predictor variables, attitude and subjective social norm were confirmed. In other words, results of analyses evidenced the contribution of TRA to explaining the underlying beliefs that enhance or thwart participation. Additionally, faculty in this study possessed positive attitudes towards the participation in online teaching, and further analyses supported the use of TRA in this research context. [source] The value of the PedsQLTM in assessing quality of life in survivors of childhood cancerCHILD: CARE, HEALTH AND DEVELOPMENT, Issue 2 2003C. Eiser Abstract Aims To determine differences in ratings of quality of life (QOL) depending on respondent (mother or child) and implications for the validity of measures of QOL, and interpretation of scores. Method Forty-five survivors of acute lymphoblastic leukaemia (ALL) and 23 survivors of central nervous system (CNS) tumours and their mothers completed a generic measure of QOL: the Pediatric Quality of Life Inventory TM Version 4.0 (PedsQLTM4.0; Varni et al., 2001). Results Although correlations between mother and survivor ratings were largely moderate to good, further analyses showed that mothers reported QOL to be worse than survivors. Both mothers and survivors rated physical health worse than psychological health, and survivors of a CNS tumour had poorer QOL than survivors of ALL. Although survivors of ALL reported reasonably good physical health, their psychosocial health was more adversely affected. Conclusions Implications for further use of the PedsQLTM 4.0 in the clinical or research context are discussed. Incidental findings highlight some limitations of the PedsQLTM4.0 for work with this population. [source] Are forest birds categorised as "edge species" strictly associated with edges?ECOGRAPHY, Issue 4 2003Louis Imbeau In recent years, studies of bird-habitat relationships undertaken in the context of habitat fragmentation have led to the widespread use of species categorisation according to their response to edge alongside mature forest patches (edge species, interior species, interior-edge generalist species). In other research contexts, especially in less fragmented landscapes dominated by a forested land base in various age classes, bird-habitat relationships are often described in relation to their use of various successional stages (early-successional species, mature forest species, generalist species). A simple comparison of these two commonly-used classifications schemes in a close geographical range for 60 species in eastern North America as well as for 36 species in north-western Europe clearly reveals that in these two particular biomes the two classifications are not independent. We believe that this association is not only a semantic issue and has important ecological consequences. For example, almost all edge species are associated with early-successional habitats when a wide range of forest age-classes are found in a given area. Accordingly, we suggest that most species considered to prefer edge habitats in agricultural landscapes are in fact only early-successional species that could not find shrubland conditions apart from the exposed edges of mature forest fragments. To be considered a true edge species, a given species should require the simultaneous availability of more than one habitat type and consequently should be classified as a habitat generalist in its use of successional stages. However, 28 out of 30 recognised edge species were considered habitat specialists in terms of successional status. Based on these results, we conclude that "real edge species" are probably quite rare and that we should make a difference between true edge species and species which in some landscapes, happen to find their habitat requirements on edges. [source] The nurse,family partnership: An evidence-based preventive interventionINFANT MENTAL HEALTH JOURNAL, Issue 1 2006David L. Olds Pregnancy and the early years of the child's life offer an opportune time to prevent a host of adverse maternal, child, and family outcomes that are important in their own right, but that also reflect biological, behavioral, and social substrates in the child and family that affect family formation and future life trajectories. This article summarizes a 27-year program of research that has attempted to improve early maternal and child health and future life options with prenatal and infancy home visiting by nurses. The program is designed for low-income mothers who have had no previous live births. The home-visiting nurses have three major goals: to improve the outcomes of pregnancy by helping women improve their prenatal health, to improve the child's health and development by helping parents provide more sensitive and competent care of the child, and to improve parental life course by helping parents plan future pregnancies, complete their education, and find work. The program has been tested in three separate large-scale, randomized controlled trials with different populations living in different contexts. Results from these trials indicate that the program has been successful in achieving two of its most important goals: (a) the improvement of parental care of the child as reflected in fewer injuries and ingestions that may be associated with child abuse and neglect and better infant emotional and language development; and (b) the improvement of maternal life course, reflected in fewer subsequent pregnancies, greater work-force participation, and reduced dependence on public assistance and food stamps. The impact on pregnancy outcomes is equivocal. In the first trial, the program also produced long-term effects on the number of arrests, convictions, emergent substance use, and promiscuous sexual activity of 15-year-old children whose nurse-visited mothers were low-income and unmarried when they registered in the study during pregnancy. In general, the impact of the program was greater on those segments of the population at greater risk for the particular outcome domain under examination. Since 1996, the program has been offered for public investment outside of research contexts. Careful attention has been given to ensuring that organizational and community contexts are favorable for development of the program, to providing excellent training and guidance to the nurses in their use of the program's visit-by-visit guidelines, to monitoring the functioning of the program with a comprehensive clinical information system, and to improving the performance of the programs over time with continuous improvement strategies. [source] DSM categories and dimensions in clinical and research contextsINTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue S1 2007Helena Chmura Kraemer Abstract An enhancement to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) is currently under consideration, one that would enhance both the reliability and validity of the Diagnostic and Statistical Manual (DSM) diagnoses: the addition of a dimensional adjunct to each of the traditional categorical diagnoses of the DSM. We first review the history and context of this proposal and define the concepts on which this dimensional proposal is based. The advantages of dimensional measures over categorical measures have long been known, but we here illustrate what is known with a theoretical and a practical demonstration of the potential effects of this addition. Possible objections to the proposal are discussed, concluding with some general criteria for implementing this proposal. Copyright © 2007 John Wiley & Sons, Ltd. [source] Emotional arousal and gender differences in aggression: A meta-analysisAGGRESSIVE BEHAVIOR, Issue 5 2002George P. Knight Abstract This meta-analysis investigated the possibility that gender differences in aggression, and the variability in these differences, are a function of gender differences in the regulation of arousal generated in emotionally evocative contexts. The sample of studies for this analysis was based on an exhaustive search of the relevant research reports from 1965,1999. Studies were excluded from the sample if they were case studies; investigated spousal/familial or societal violence, war, suicide, or political violence; involved clinical or deviant participants; included fewer than 10 participants; included all male, all female, all non-Caucasian, or non-US/non-Canadian participants. Based on previous evidence that males may be more easily aroused by aggressive-relevant emotional stimuli than females, and that males may have more difficulty regulating emotionally arousing states than females, we hypothesized that the magnitude of the gender differences in aggression would covary, in a nonlinear manner, with the emotional evocativeness of the study context. Consistent with our hypothesis, the magnitude of gender differences in aggression was relatively small in research contexts that appeared to produce no or large increments in emotional arousal and larger (favoring males) in contexts that appeared to produce small or medium increments in emotional arousal. Aggr. Behav. 28:366,393, 2002. © 2002 Wiley-Liss, Inc. [source] Developing an audit tool to assess genetic servicesNURSING & HEALTH SCIENCES, Issue 2 2005Heather Skirton phd The aim of this study was to use clients' accounts and factor analysis to develop a robust assessment and audit tool for clinical genetic services. Qualitative data abstracted from published studies were used to generate a number of statements (n = 57) related to outcomes of genetic services. The resulting questionnaire was mailed to clients of the Wales genetic service, who were asked to rank each statement on a 7-point Likert type scale. Ninety-seven anonymised responses were received (73% response rate) and subjected to factor analysis. Six main factors were found to contribute to the outcome of the service and were labeled (i) enhanced understanding; (ii) positive psychological change; (iii) respect for autonomy; (iv) adaptation; (v) disequilibrium; and (vi) value of contact. The tool will be validated for use in clinical and research contexts. [source] Compound Democracy and the Control of Corruption: A Cross-Country InvestigationPOLICY STUDIES JOURNAL, Issue 4 2004Alok K. Bohara In this article we evaluate the influence of democracy on perceived levels of corruption. We argue that the control of corruption depends on the compensation and accountability of public officials, and on an open and competitive economy. We analyze the influence of democracy, controlling for the influence of other political and economic factors including federalism, economic development, and economic competition. The findings for the importance of economic factors are consistent. The finding in earlier research that federalism increases corruption is not robust. The findings for democracy are influenced importantly by the way that democracy is measured, but we do find that citizens' repetitive participation in competitive elections increases the control of corruption. In doing so, we move beyond the composite indices of democracy in constructing an alternative compound measure of democracy, which we argue is likely to be useful in other research contexts [source] Assessment of child problem behaviors by multiple informants: a longitudinal study from preschool to school entryTHE JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES, Issue 10 2007David C.R. Kerr Background:, Children's early problem behavior that manifests in multiple contexts is often more serious and stable. The concurrent and predictive validity of ratings of externalizing and internalizing by four informants was examined at preschool and early school age in an at-risk sample. Methods:, Two hundred forty children were assessed by mothers and fathers (Child Behavior Checklist (CBCL)), and teachers and laboratory examiners (Teacher Report Form (TRF)) at ages 3 and 5 years. Results:, All informants' ratings of externalizing converged on a common factor at ages 3 and 5 that showed strong stability over time (, = .80). All informants' age 3 externalizing ratings significantly predicted the problem factor at age 5; mothers', fathers', and teachers' ratings were independently predictive. Ratings of internalizing (except by examiners at age 3) also converged at both ages; the problem factor showed medium stability (, = .39) over time. Only fathers' ratings of age 3 internalizing predicted the age 5 problem factor. Conclusions:, Findings support the value of multi-informant assessment, uphold calls to include fathers in childhood research, and suggest that examiners provide valid, though non-unique assessment data. Examiner contributions may prove useful in many research contexts. [source] Does Memory Development Belong on an Endangered Topic List?CHILD DEVELOPMENT, Issue 1 2000Deanna Kuhn Although memory has long been regarded as a central and well-defined topic within the field of cognitive development, developments in and related to the study of memory increasingly suggest that the study of memory needs to be situated in a number of broader conceptual and research contexts. Four of these contexts are identified here and the ways they accommodate memory phenomena are examined: (1) knowledge (what is remembered?); (2) comprehension (what does it mean?); (3) context/function (why remember?); and (4) strategy (how to remember?). Memories, it is suggested, are best examined as knowledge structures that are the product of efforts to understand and to know, and memorizing is a socially situated activity undertaken in the service of individual or social goals. [source] Peer Led Focus Groups and Young PeopleCHILDREN & SOCIETY, Issue 4 2006Cathy Murray Peer led focus groups, a qualitative social science research method, and their use with young people are examined. The paper outlines three developments that have contributed to their emergence, namely: traditional focus groups, peer education and participatory research. Drawing on a study in progress, the advantages and challenges associated with peer led focus groups are discussed. A key benefit is that the power differential between the adult researcher and the researched is removed, at least at the point of data collection, rendering peer led focus groups one of few research contexts in which young people can speak collectively with no adult present. [source] | ||||||||||||||||