Research Advances (research + advance)

Distribution by Scientific Domains

Kinds of Research Advances

  • recent research advance


  • Selected Abstracts


    Educational and Research Advances Stemming from the Academic Emergency Medicine Consensus Conference in Knowledge Translation

    ACADEMIC EMERGENCY MEDICINE, Issue 8 2010
    Eddy S. Lang MD
    ACADEMIC EMERGENCY MEDICINE 2010; 17:865,869 © 2010 by the Society for Academic Emergency Medicine Abstract The 2007 Academic Emergency Medicine (AEM) consensus conference "Knowledge Translation in Emergency Medicine" yielded a number of initiatives in both education and research that directly reflected the conference's published objectives and recommendations. One research initiative, CONCERT, is a national consortium of chronic obstructive pulmonary disease (COPD) investigators who set forth an effort designed to optimize COPD care through the identification of gaps between research and practice in diagnosis and management of the chronic and acute care aspects of this disease. In addition to CONCERT, educational programs designed to identify barriers to evidence implementation and to develop solutions to achieve uptake through multidisciplinary collaboration have emerged that reflect the impact of the consensus conference. This article describes these initiatives and highlights the potential for future innovative opportunities. [source]


    Management of systemic lupus erythematosus in the coming decade: potentials and challenges

    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, Issue 4 2006
    Hiok Hee CHNG
    Abstract The management of systemic lupus erythematosus (SLE) has improved in the past 50 years, but there is still a 3,5-fold increased mortality compared to the general population, with major organ failure due to active disease, infection and cardiovascular disease as the major challenges for the coming decade. Research advances at cellular, molecular and genetic levels enhance our understanding of the immunopathogenic mechanisms of SLE, leading to the development of drugs targeting specific sites of immune dysregulation , with therapies directed at cytokines, B- and T-cells, and their interactions showing promise. Advances are expected in the field of haematopoietic stem cell transplant (HSCT) as a therapeutic option for a subset of patients. Furthermore, some non-traditional immunomodulating therapies like statins, leflunomide and tacrolimus may prove useful as alternative or adjunct treatment in some patients. A better understanding of how current immunosuppressants act at the cellular and molecular level should guide the re-evaluation of the indications, doses and duration of therapy in clinical trials using these agents, many of which have not been subjected to proper double-blinded placebo-controlled studies. Research on triggers of SLE onset and flare of activity continues to yield information helpful in prevention. The evidence on the impact of psychosocial and economic factors on the outcome of SLE is overwhelming and the rheumatology community should enlist the assistance of other healthcare professionals, patient advocates and local health authorities to address these issues pertinent to good patient care and outcome. [source]


    5.3 Global challenges in research and strategic planning

    EUROPEAN JOURNAL OF DENTAL EDUCATION, Issue 2002
    Bruce J. Baum
    Health sciences research is experiencing dramatic progress. How can dental schools throughout the world best make these research advances relevant for dental students, as well as providing them with the means to assess and utilize the research advances that will occur in the future? This complex question presents a critical challenge to the dental educational community. Research is clearly integral to the mission of dental education. By providing dental students with active learning strategies, dental educators can inculcate the ability for independent scientific thinking and thereby develop reflective as well as technically competent practitioners. However, there is a shortage of well-trained individuals to fill faculty and research positions in certain parts of the world. Global networks for mutual information exchange are imperative to overcome resource limitations in individual institutions, as is dedicated funding for research in the dental educational setting. [source]


    Reversible and High-Capacity Nanostructured Electrode Materials for Li-Ion Batteries

    ADVANCED FUNCTIONAL MATERIALS, Issue 10 2009
    Min Gyu Kim
    Abstract Reversible nanostructured electrode materials are at the center of research relating to rechargeable lithium batteries, which require high power, high capacity, and high safety. The higher capacities and higher rate capabilities for the nanostructured electrode materials than for the bulk counterparts can be attributed to the higher surface area, which reduces the overpotential and allows faster reaction kinetics at the electrode surface. These electrochemical enhancements can lead to versatile potential applications of the batteries and can provide breakthroughs for the currently limited power suppliers of mobile electronics. This Feature Article describes recent research advances on nanostructured cathode and anode materials, such as metals, metal oxides, metal phosphides and LiCoO2, LiNi1,xMxO2 with zero-, one-, two-, and three-dimensional morphologies. [source]


    New research advances for treating metastatic melanoma

    INTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 6 2010
    Ettore Minutilli MD
    No abstract is available for this article. [source]


    God's will, God's punishment, or God's limitations?

    JOURNAL OF CLINICAL PSYCHOLOGY, Issue 6 2007
    Religious coping strategies reported by young adults living with serious mental illness
    Qualitative research has demonstrated that religious meaning-making coping, defined as attributions of a stressful life event that involve the sacred, is particularly relevant to persons with serious mental illness. However, recent research advances in the study of religious coping have yet to be employed in clinical samples. This longitudinal study examines religious meaning-making coping in a sample of 48 young adults diagnosed with schizophrenia or bipolar disorder over a one-year period. Young adults with mental illness generally reported using religious meaning-making coping in levels comparable to nonpsychiatric samples. Reports of benevolent religious reappraisals were associated with perceptions of positive mental health, whereas punishing God reappraisals and reappraisals of God's power were associated with self-reported distress and personal loss. Religious coping variables accounted for variation in adults' reports of psychiatric symptoms and personal loss one year later over and above demographic and global religious variables. Implications of findings for clinical practice are discussed. © 2007 Wiley Periodicals, Inc. J Clin Psychol. [source]


    Cordyceps fungi: natural products, pharmacological functions and developmental products

    JOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 3 2009
    Professor Xuanwei Zhou
    Abstract Objectives Parasitic Cordyceps fungi, such as Cordyceps sinensis, is a parasitic complex of fungus and caterpillar, which has been used for medicinal purposes for centuries particularly in China, Japan and other Asian countries. This article gives a general idea of the latest developments in C. sinensis research, with regard to the active chemical components, the pharmacological effects and the research and development of products in recent years. Key findings The common names for preparations include DongChongXiaCao in Chinese, winter worm summer grass in English. It has many bioactive components, such as 3,-deoxyadenosine, cordycepic acid and Cordyceps polysaccharides. It is commonly used to replenish the kidney and soothe the lung, and for the treatment of fatigue. It also can be used to treat conditions such as night sweating, hyposexuality, hyperglycaemia, hyperlipidaemia, asthenia after severe illness, respiratory disease, renal dysfunction, renal failure, arrhythmias and other heart disease and liver disease. Because of its rarity and outstanding curative effects, several mycelia strains have been isolated from natural Cordyceps and manufactured by fermentation technology, and are commonly sold as health food products. In addition, some substitutes such as C. militaris and adulterants also have been used; therefore, quality control of C. sinensis and its products is very important to ensure their safety and efficacy. Summary Recent research advances in the study of Cordyceps, including Cordyceps mushrooms, chemical components, pharmacological functions and developmental products, has been reviewed and discussed. Developing trends in the field have also been appraised. [source]


    A primary care provider's guide to preventive and acute care management of adults and children with sickle cell disease

    JOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS, Issue 5 2009
    Ardie Pack-Mabien RNC, CRNP (Clinical Nurse Practitioner & Nurse Manager)
    Abstract Purpose: To familiarize primary care providers (PCPs) with the pathophysiological processes, diagnostic evaluation, and medical management of sickle hemoglobinopathies and their complications. Current standards of care, clinical research advances, and new treatment options will also be addressed to assist PCPs in the management of sickle cell disease (SCD). Data sources: A selective search and review of the current literature on SCD and the authors' experience. Conclusions: Management of individuals with SCD is very complex, requiring a multidisciplinary approach that includes the patient or parent, PCP, specialist, nurse, and social worker. More patients living with SCD are relying on PCPs in nonspecialty practices for comprehensive disease management. Implications for practice: Newborn screening detects new cases of SCD annually. The median life expectancy has more than doubled for individuals with sickle cell anemia. Healthcare providers are now in an era of increased routine screening, assessment, and management of chronic complications from this illness not previously seen in the care of adults with SCD. [source]


    Program: Twenty Fourth Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson's Disease and Other Movement Disorders

    MOVEMENT DISORDERS, Issue 6 2010
    Article first published online: 26 APR 2010
    The symposium will consist of current issues in genetic and environmental contributions to Parkinson's disease and other movement disorders with peer-reviewed platform and poster presentations designed to communicate recent research advances, including new pharmacological and non-pharmacological treatment options, in the field of Parkinson's disease, Huntington's disease, ataxia, dystonia, myoclonus, Tourette's syndrome, tremor and other movement disorders thereby enhancing patient care. [source]


    Program: Twenty Third Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson's Disease and Other Movement Disorders

    MOVEMENT DISORDERS, Issue 12 2009
    Article first published online: 11 SEP 200
    The symposium will consist of two keynote speakers and peer-reviewed platform and poster presentations designed to communicate recent research advances, including new pharmacological and non-pharmacological treatment options, in the field of Parkinson's disease, Huntington disease, ataxia, dystonia, myoclonus, Tourette's syndrome, Essential Tremor and other movement disorders thereby enhancing patient care. Professionals in neurology and related disciplines as well as practitioners, psychologists, educators, and researchers are invited to attend. The gaps in clinical practice we wish to address are the unmet needs pertaining to the translational and clinical evaluation, along with the care and treatment of patients and families affected by Parkinson's disease and other movement disorders. At the conclusion of this session, participants should be able to: 1) Identify and describe by scholarly review, oral presentation and group discussion the current research into the diagnosis, prevention and treatment of Parkinson's disease (PD) and Essential Tremor (ET) which may be relevant to current treatment or which may lead to the development of further research protocols; 2) Distinguish and assess the important advances in research and clinical treatments relating to Parkinson's disease and Essential Tremor in terms of available treatment options or new methodologies for clinical research; 3) Explain new pharmacological and non-pharmacological treatment options available for Parkinson's disease and other movement disorders in connection with their clinical practice or with regard to further clinical research methods; 4) Interpret the mechanisms (genetic, environmental, pathophysiology, neurobiology) linked to Parkinson's disease and other movement disorders when assessing Parkinson's disease or other movement disorder patients or when developing new research protocols; and 5) Employ diagnostic approaches and tools available for assessing Parkinson's disease and Essential Tremor when diagnosing new patients or when conducting clinical research. [source]


    Thirty Years of Mergers and Acquisitions Research: Recent Advances and Future Opportunities

    BRITISH JOURNAL OF MANAGEMENT, Issue S1 2006
    Susan Cartwright
    The complex phenomenon that mergers and acquisitions (M&As) represent has attracted substantial interest from a variety of management disciplines over the past 30 years. Three primary streams of enquiry can be identified within the strategic and behavioural literature, which focus on the issues of strategic fit, organizational fit and the acquisition process itself. The recent achievements within each of these research streams are briefly reviewed. However, in parallel to these research advances, the failure rates of mergers and acquisitions have remained consistently high. Possible reasons for this dichotomy are discussed, which in turn highlight the significant opportunities that remain for future M&A research. [source]


    Perils and Promise in Defining and Measuring Mindfulness: Observations From Experience

    CLINICAL PSYCHOLOGY: SCIENCE AND PRACTICE, Issue 3 2004
    Kirk Warren Brown
    As mindfulness research advances on a variety of fronts, it has become increasingly important to carefully define and measure the construct. In this commentary, we draw from our recent research experience on these topics in addressing four issues of primary concern to Bishop et al: The nature of mindfulness, the role of acceptance in the phenomenon, the relation between mindfulness and meditation, and the measurement of mindfulness in meditative and other contexts. [source]